PubRank

Allan Balmain

Author PubWeight™ 82.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 2009 6.03
2 Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. Nature 2004 4.35
3 FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Science 2008 3.78
4 Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 2003 3.70
5 Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat Cell Biol 2002 3.52
6 Stem-cell hierarchy in skin cancer. Nat Rev Cancer 2003 2.36
7 Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer. Am J Pathol 2007 2.23
8 Kras regulatory elements and exon 4A determine mutation specificity in lung cancer. Nat Genet 2008 2.05
9 Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays. Nat Biotechnol 2002 2.04
10 Genomic segmental polymorphisms in inbred mouse strains. Nat Genet 2004 1.93
11 Genetic architecture of mouse skin inflammation and tumour susceptibility. Nature 2009 1.89
12 A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice. Nat Genet 2006 1.79
13 Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res 2005 1.71
14 Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis 2005 1.61
15 Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice. Cancer Cell 2007 1.59
16 HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proc Natl Acad Sci U S A 2007 1.58
17 Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. Mol Cell Biol 2002 1.56
18 Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature 2007 1.54
19 Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back. Am J Med Genet A 2010 1.36
20 Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression. Genes Dev 2004 1.31
21 Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol 2013 1.30
22 Genetic interactions between Pten and p53 in radiation-induced lymphoma development. Oncogene 2003 1.28
23 Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice. Cancer Res 2003 1.27
24 Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition. Cancer Res 2006 1.25
25 Keratin 16 regulates innate immunity in response to epidermal barrier breach. Proc Natl Acad Sci U S A 2013 1.16
26 Characterizing the protective component of the alphabeta T cell response to transplantable squamous cell carcinoma. J Invest Dermatol 2004 1.11
27 Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer. J Clin Oncol 2010 1.10
28 Genomic approaches to identification of tumour-susceptibility genes using mouse models. Curr Opin Genet Dev 2003 1.08
29 Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility. Genome Biol 2011 1.08
30 Systems genetics analysis of cancer susceptibility: from mouse models to humans. Nat Rev Genet 2009 1.06
31 Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development. Mol Cancer Res 2012 1.05
32 A gain of function TGFB1 polymorphism may be associated with late stage prostate cancer. Cancer Epidemiol Biomarkers Prev 2004 1.04
33 p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo. Oncogene 2005 1.04
34 Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway. Cancer Res 2005 1.00
35 Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2004 0.98
36 Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes Dev 2011 0.98
37 Developing novel oncolytic adenoviruses through bioselection. J Virol 2003 0.97
38 Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility. Proc Natl Acad Sci U S A 2006 0.97
39 Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer. Mol Cancer Res 2011 0.96
40 Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas. Nat Commun 2013 0.95
41 Genomic instability in radiation-induced mouse lymphoma from p53 heterozygous mice. Oncogene 2005 0.95
42 Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression. Genes Dev 2013 0.94
43 High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling. J Biol Chem 2002 0.92
44 Crosstalk between Pten and Ras signaling pathways in tumor development. Cell Cycle 2005 0.89
45 Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility. PLoS One 2012 0.88
46 Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus. BMC Genomics 2008 0.88
47 The genetics of cancer susceptibility: from mouse to man. Toxicol Pathol 2004 0.87
48 Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice. J Invest Dermatol 2012 0.86
49 Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity. Genome 2004 0.85
50 Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants. J Virol 2003 0.85
51 Cancer: new-age tumour suppressors. Nature 2002 0.83
52 Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis. Proc Natl Acad Sci U S A 2010 0.82
53 Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas. Blood 2011 0.81
54 Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology. J Invest Dermatol 2013 0.79
55 Novel approaches to identify low-penetrance cancer susceptibility genes using mouse models. Recent Results Cancer Res 2003 0.78
56 Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes. Clin Cancer Res 2013 0.78
57 C/EBPδ: friend or foe? a novel role for C/EBPδ in metastasis. EMBO J 2010 0.76
58 Cancer: dangerous liaisons. Nature 2004 0.75