Published in BMC Proc on December 15, 2009
A new gene-based association test for genome-wide association studies. BMC Proc (2009) 1.37
Genome-wide association studies: quality control and population-based measures. Genet Epidemiol (2009) 1.14
Effect of population stratification on the identification of significant single-nucleotide polymorphisms in genome-wide association studies. BMC Proc (2009) 1.11
Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS. Genet Epidemiol (2010) 0.99
The challenge of detecting epistasis (G x G interactions): Genetic Analysis Workshop 16. Genet Epidemiol (2009) 0.99
Incorporating group correlations in genome-wide association studies using smoothed group Lasso. Biostatistics (2012) 0.98
Risk estimation and risk prediction using machine-learning methods. Hum Genet (2012) 0.98
Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses. BMC Proc (2009) 0.91
Nonparametric Risk and Nonparametric Odds in Quantitative Genetic Association Studies. Sci Rep (2015) 0.87
Fisher's method of combining dependent statistics using generalizations of the gamma distribution with applications to genetic pleiotropic associations. Biostatistics (2013) 0.82
Analysis of multiple phenotypes. Genet Epidemiol (2009) 0.81
Accounting for linkage disequilibrium in genome-wide association studies: A penalized regression method. Stat Interface (2013) 0.81
Genetic Analysis Workshop 16: introduction to workshop summaries. Genet Epidemiol (2009) 0.81
Accelerating haplotype-based genome-wide association study using perfect phylogeny and phase-known reference data. PLoS One (2011) 0.81
A network-based kernel machine test for the identification of risk pathways in genome-wide association studies. Hum Hered (2014) 0.80
Haplotype association analysis of North American Rheumatoid Arthritis Consortium data using a generalized linear model with regularization. BMC Proc (2009) 0.79
Genome-wide association studies for discrete traits. Genet Epidemiol (2009) 0.78
A novel kernel for correcting size bias in the logistic kernel machine test with an application to rheumatoid arthritis. Hum Hered (2013) 0.77
A powerful score-based test statistic for detecting gene-gene co-association. BMC Genet (2016) 0.76
Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium. Sci Rep (2015) 0.76
Power Calculation of Multi-step Combined Principal Components with Applications to Genetic Association Studies. Sci Rep (2016) 0.75
Robust joint analysis with data fusion in two-stage quantitative trait genome-wide association studies. Comput Math Methods Med (2013) 0.75
Improving the signal-to-noise ratio in genome-wide association studies. Genet Epidemiol (2009) 0.75
A two-phase procedure for non-normal quantitative trait genetic association study. BMC Bioinformatics (2016) 0.75
Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies. Comput Math Methods Med (2017) 0.75
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum (1987) 14.21
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet (2004) 13.71
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med (2007) 12.24
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med (2007) 9.80
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum (2006) 9.52
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet (2005) 6.61
Analysis and application of European genetic substructure using 300 K SNP information. PLoS Genet (2008) 6.42
European population substructure: clustering of northern and southern populations. PLoS Genet (2006) 5.27
The New York Cancer Project: rationale, organization, design, and baseline characteristics. J Urban Health (2004) 5.21
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis Rheum (2005) 5.18
The prognostic value of anti-cyclic citrullinated peptide antibody in patients with recent-onset rheumatoid arthritis. Arthritis Rheum (2000) 4.10
PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. Am J Hum Genet (2005) 3.95
A review of the MHC genetics of rheumatoid arthritis. Genes Immun (2004) 3.77
Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet (2008) 3.18
The genetics revolution and the assault on rheumatoid arthritis. Arthritis Rheum (1999) 2.92
Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles. Arthritis Rheum (2005) 2.88
New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility. Arthritis Rheum (2005) 2.48
Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. Am J Hum Genet (2002) 2.47
Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations. Arthritis Rheum (2009) 1.92
Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene. Proc Natl Acad Sci U S A (2007) 1.29
The shared epitope hypothesis in rheumatoid arthritis: evaluation of alternative classification criteria in a large UK Caucasian cohort. Arthritis Rheum (2008) 1.16
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Strong association of de novo copy number mutations with autism. Science (2007) 27.84
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet (2008) 16.17
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet (2004) 13.71
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med (2007) 12.24
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci U S A (2003) 11.65
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med (2007) 9.80
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (2010) 9.61
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med (2008) 9.61
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet (2009) 8.39
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet (2006) 6.98
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet (2005) 6.61
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet (2008) 6.42
Analysis and application of European genetic substructure using 300 K SNP information. PLoS Genet (2008) 6.42
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med (2006) 6.17
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). Annu Rev Immunol (2009) 5.91
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet (2008) 5.43
European population substructure: clustering of northern and southern populations. PLoS Genet (2006) 5.27
The New York Cancer Project: rationale, organization, design, and baseline characteristics. J Urban Health (2004) 5.21
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis Rheum (2005) 5.18
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet (2012) 5.11
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet (2008) 5.08
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes. Am J Hum Genet (2005) 5.00
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum (2002) 4.98
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med (2009) 4.97
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med (2011) 4.81
Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study. Arthritis Rheum (2004) 4.77
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A (2007) 4.71
Early-onset stroke and vasculopathy associated with mutations in ADA2. N Engl J Med (2014) 4.70
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. Hum Mutat (2009) 4.65
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet (2004) 4.46
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet (2012) 4.46
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nat Genet (2012) 4.41
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nat Genet (2008) 4.33