Published in BMC Proc on December 15, 2009
A machine learning pipeline for quantitative phenotype prediction from genotype data. BMC Bioinformatics (2010) 0.95
The role of phenotype in gene discovery in the whole genome sequencing era. Hum Genet (2012) 0.89
Genetic Analysis Workshop 16: introduction to workshop summaries. Genet Epidemiol (2009) 0.81
Systems biology data analysis methodology in pharmacogenomics. Pharmacogenomics (2011) 0.80
Genetics Analysis Workshop 16 Problem 2: the Framingham Heart Study data. BMC Proc (2009) 2.31
Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data. BMC Proc (2009) 2.12
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA (2005) 23.44
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Mammographic density and the risk and detection of breast cancer. N Engl J Med (2007) 14.32
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet (2011) 9.10
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. PLoS One (2010) 7.48
A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22
Statistical analysis of rare sequence variants: an overview of collapsing methods. Genet Epidemiol (2011) 6.18
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Gene map of the extended human MHC. Nat Rev Genet (2004) 6.01
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol (2013) 5.89
Asthma in exercising children exposed to ozone: a cohort study. Lancet (2002) 5.84
Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol (2012) 5.70
Exploiting gene-environment interaction to detect genetic associations. Hum Hered (2007) 5.63
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Stem cell gene expression programs influence clinical outcome in human leukemia. Nat Med (2011) 5.24
Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation (2008) 5.20
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
Age-related lobular involution and risk of breast cancer. J Natl Cancer Inst (2006) 5.12
Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
An integrated epigenetic and genetic approach to common human disease. Trends Genet (2004) 4.89
Inhibitors of factor VIII in black patients with hemophilia. N Engl J Med (2009) 4.82
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54
Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet (2010) 4.51
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet (2009) 4.38
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Gene-environment interaction in genome-wide association studies. Am J Epidemiol (2008) 3.96
Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol (2003) 3.87
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. JAMA (2012) 3.85
Personalized epigenomic signatures that are stable over time and covary with body mass index. Sci Transl Med (2010) 3.81
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
A testing framework for identifying susceptibility genes in the presence of epistasis. Am J Hum Genet (2005) 3.69
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage (2009) 3.66
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. Nat Genet (2010) 3.63
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int J Epidemiol (2012) 3.62
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet (2013) 3.42
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
Breast tissue composition and susceptibility to breast cancer. J Natl Cancer Inst (2010) 3.39
BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst (2003) 3.37
No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. Am J Psychiatry (2008) 3.23
Sparse canonical correlation analysis with application to genomic data integration. Stat Appl Genet Mol Biol (2009) 3.22
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Predicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trials. Stroke (2008) 3.21
A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet (2002) 3.19
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data. Bioinformatics (2010) 3.09
Ultrasound imaging for lumbar punctures and epidural catheterisations: systematic review and meta-analysis. BMJ (2013) 3.02
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
Mammographic density and breast cancer risk: current understanding and future prospects. Breast Cancer Res (2011) 2.86
Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am J Psychiatry (2007) 2.84
Health effects of the 2003 Southern California wildfires on children. Am J Respir Crit Care Med (2006) 2.81
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
US or CT for Diagnosis of Appendicitis in Children and Adults? A Meta-Analysis. Radiology (2006) 2.74
Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis. J Mol Med (Berl) (2007) 2.69
Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial. Lancet (2011) 2.62
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
Effect of fructose on body weight in controlled feeding trials: a systematic review and meta-analysis. Ann Intern Med (2012) 2.58
Features of effective computerised clinical decision support systems: meta-regression of 162 randomised trials. BMJ (2013) 2.58
Preterm birth and low birth weight among in vitro fertilization singletons: a systematic review and meta-analyses. Eur J Obstet Gynecol Reprod Biol (2009) 2.52
Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet (2006) 2.49
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study. Lancet Oncol (2013) 2.48
Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A (2002) 2.47
Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet (2010) 2.47
Psychiatric genetics: a survey of psychiatrists' knowledge, opinions, and practice patterns. J Clin Psychiatry (2005) 2.46
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes (2004) 2.46
Body size, mammographic density, and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2006) 2.44
Genetic and environmental factors influencing the human factor H plasma levels. Immunogenetics (2004) 2.43
Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium. J Natl Cancer Inst (2014) 2.40
Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and meta-analyses. BMJ (2010) 2.37