Published in Genes Dev on March 01, 1991
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev (2002) 3.80
A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol (2002) 3.09
Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol Cell Biol (1998) 3.09
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J Cell Biol (1993) 2.95
The Wnts. Genome Biol (2001) 2.90
Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev (2003) 2.34
Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev (2002) 2.01
A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse. BMC Dev Biol (2010) 1.92
Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol Cell Biol (1992) 1.88
Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development. Development (2008) 1.87
The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Mol Cell Biol (1992) 1.75
Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A (1994) 1.54
Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells. Nature (2011) 1.50
Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line. Mol Biol Cell (1992) 1.39
Diversification of the Wnt gene family on the ancestral lineage of vertebrates. Proc Natl Acad Sci U S A (1992) 1.18
Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction. Development (2009) 1.14
Wnt/frizzled-2 signaling induces aggregation and adhesion among cardiac myocytes by increased cadherin-beta-catenin complex. J Cell Biol (2000) 1.05
A fast and sensitive alternative for β-galactosidase detection in mouse embryos. Development (2012) 1.04
Wnt-1-inducing factor-1: a novel G/C box-binding transcription factor regulating the expression of Wnt-1 during neuroectodermal differentiation. Mol Cell Biol (1993) 1.03
Interaction of Wnt-1 proteins with the binding protein BiP. Mol Cell Biol (1992) 1.00
Delineating a conserved genetic cassette promoting outgrowth of body appendages. PLoS Genet (2013) 0.99
Developmental abnormalities in cultured mouse embryos deprived of retinoic by inhibition of yolk-sac retinol binding protein synthesis. Proc Natl Acad Sci U S A (1996) 0.99
Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol (2009) 0.98
Zebrafish wnt3 is expressed in developing neural tissue. Dev Dyn (2009) 0.96
The genesis of avian neural crest cells: a classic embryonic induction. Proc Natl Acad Sci U S A (1996) 0.92
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
Shared signaling pathways in normal and breast cancer stem cells. J Carcinog (2011) 0.91
Functional genetic targeting of embryonic kidney progenitor cells ex vivo. J Am Soc Nephrol (2014) 0.90
Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. Development (2015) 0.88
A role for Quox-8 in the establishment of the dorsoventral pattern during vertebrate development. Proc Natl Acad Sci U S A (1992) 0.87
Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum. Dev Biol (2008) 0.87
WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. PLoS One (2013) 0.86
Estrogen regulation of Dkk1 and Wnt/β-Catenin signaling in neurodegenerative disease. Brain Res (2012) 0.84
Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system. Stem Cells (2015) 0.84
Wnt5a controls neurite development in olfactory bulb interneurons. ASN Neuro (2011) 0.82
Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube. Dev Dyn (2010) 0.81
Signalling through the type 1 insulin-like growth factor receptor (IGF1R) interacts with canonical Wnt signalling to promote neural proliferation in developing brain. ASN Neuro (2012) 0.78
QTL analysis of modifiers for pigmentary disorder in rats carrying Ednrb(sl) mutations. Sci Rep (2016) 0.75
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1991) 0.75
Supt20 is required for development of the axial skeleton. Dev Biol (2016) 0.75
Wnt signaling: a common theme in animal development. Genes Dev (1997) 12.94
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell (1982) 9.29
Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol (1998) 9.24
A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature (1996) 7.04
Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature (1984) 5.53
Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer. N Engl J Med (1988) 4.06
Information access. Building a "GenBank" of the published literature. Science (2001) 3.95
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell (1987) 3.78
Beta-catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev (1998) 3.65
A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature (1999) 3.22
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity (2000) 3.19
Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene. Mol Cell Biol (1987) 2.96
Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev (1999) 2.78
Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell (1989) 2.61
The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev (1994) 2.50
The dishevelled protein is modified by wingless signaling in Drosophila. Genes Dev (1995) 2.46
Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact. Cell (1984) 2.44
dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature (1994) 2.29
Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell (1998) 2.23
Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells. Nature (1994) 2.20
Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes Dev (2001) 2.16
WNT signaling in the control of hair growth and structure. Dev Biol (1999) 2.13
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J (1993) 2.12
Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J (1997) 1.97
Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. Proc Natl Acad Sci U S A (1990) 1.94
Wnts as ligands: processing, secretion and reception. Oncogene (2006) 1.90
Mammary tumor induction loci in GR and DBAf mice contain one provirus of the mouse mammary tumor virus. Cell (1981) 1.89
Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev Biol (1994) 1.89
Transfection of the int-1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity. EMBO J (1987) 1.69
A new nomenclature for int-1 and related genes: the Wnt gene family. Cell (1991) 1.67
A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development (1999) 1.61
Structural analysis of a 1.7-kilobase mouse mammary tumor virus-specific RNA. J Virol (1983) 1.55
Signaling by wingless in Drosophila. Dev Biol (1994) 1.53
The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development (1992) 1.52
Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless. Mol Cell (2000) 1.49
Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma. Oncogene (2009) 1.48
The status of Wnt signalling regulates neural and epidermal fates in the chick embryo. Nature (2001) 1.43
The int genes in mammary tumorigenesis and in normal development. Trends Genet (1988) 1.43
Translation of mouse mammary tumor virus RNA: precursor polypeptides are phosphorylated during processing. Virology (1978) 1.38
The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases. Curr Biol (1998) 1.35
Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development (1999) 1.34
The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences. EMBO J (1985) 1.34
Activation of int-1 and int-2 mammary oncogenes in hormone-dependent and -independent mammary tumors of GR mice. J Virol (1987) 1.29
Involvement of mouse mammary tumor virus in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains. J Virol (1978) 1.26
Impaired maturation of mouse mammary tumor virus precursor polypeptides in lymphoid leukemia cells, producing intracytoplasmic A particles and no extracellular B-type virions. J Virol (1979) 1.17
Localization of a gene for expression of mouse mammary tumor virus antigens in the GR/Mtv-2- mouse strain. J Exp Med (1980) 1.17
Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein. Proc Natl Acad Sci U S A (1997) 1.16
DWnt-2, a Drosophila Wnt gene required for the development of the male reproductive tract, specifies a sexually dimorphic cell fate. Genes Dev (1998) 1.14
The Drosophila Wnt protein DWnt-3 is a secreted glycoprotein localized on the axon tracts of the embryonic CNS. Dev Biol (1995) 1.12
Developmental biology. Making head or tail of Dickkopf. Nature (2001) 1.11
Translating insights from development into regenerative medicine: the function of Wnts in bone biology. Semin Cell Dev Biol (2008) 1.11
A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23. Hum Mol Genet (1997) 1.10
Immunologic, virologic, and genetic aspects of mammary tumor virus-induced cell-surface antigens: presence of these antigens and the Thy 1.2 antigen on murine mammary gland and tumor cells. J Natl Cancer Inst (1975) 1.08
Isolation and expression of two novel Wnt/wingless gene homologues in Drosophila. Development (1992) 1.07
wingless signaling in the Drosophila eye and embryonic epidermis. Development (1996) 1.06
Immunohistochemical detection of the neu protein in tissue sections of human breast tumors with amplified neu DNA. Oncogene (1988) 1.05
Transient expression of the proto-oncogene int-1 during differentiation of P19 embryonal carcinoma cells. Mol Cell Biol (1989) 1.03
Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer. Semin Cancer Biol (1995) 1.02
Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells. Development (1994) 0.99
Amplification and proviral activation of several Wnt genes during progression and clonal variation of mouse mammary tumors. Oncogene (1992) 0.98
Phorbol ester-inducible T-cell-specific expression of variant mouse mammary tumor virus long terminal repeats. J Virol (1989) 0.97
Construction of a retroviral cDNA version of the int-1 mammary oncogene and its expression in vitro. Nucleic Acids Res (1986) 0.95
Molecular cloning and chromosomal assignment of the human homolog of int-1, a mouse gene implicated in mammary tumorigenesis. Mol Cell Biol (1984) 0.95
Regional expression of the Wnt-3 gene in the developing mouse forebrain in relationship to diencephalic neuromeres. Mech Dev (1992) 0.94
Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos. Dev Suppl (1993) 0.94
The activation of cellular oncogenes by proviral insertion in murine mammary cancer. Cancer Treat Res (1988) 0.94
An ancient cluster of Wnt paralogues. Trends Genet (2001) 0.93
The molecular biology of breast cancer. Biochim Biophys Acta (1991) 0.92
Quantitation of virus-induced (MLr) and normal (Thy.1.2) cell surface antigens in isolated plasma membranes and the extracellular ascites fluid of mouse leukemia cells. Cancer Res (1975) 0.92
Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression. Development (1998) 0.91
Analysis of secondary modifications of mouse mammary tumor virus proteins by two-dimensional gel electrophoresis. J Virol (1980) 0.89
Differentiation-dependent expression of provirus-activated int-1 oncogene in clonal cell lines derived from a mouse mammary tumor. Oncogene (1990) 0.88
Mutation of the human neu protein facilitates down-modulation by monoclonal antibodies. Oncogene (1990) 0.88
Mouse mammary tumor virus expression and mammary tumor development. Curr Top Microbiol Immunol (1983) 0.88
Induction of mouse mammary tumor virus RNA in mammary tumors of BALB/c mice treated with urethane, X-irradiation, and hormones. J Virol (1979) 0.88
Amplification and over-expression of the neu oncogene in human breast carcinomas. Eur J Surg Oncol (1988) 0.86
Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene. Genomics (1993) 0.85
Retroviral insertional mutagenesis in murine mammary cancer. Proc R Soc Lond B Biol Sci (1985) 0.85
Oncogene activation in human myeloid leukemia. Cancer Res (1985) 0.84
Quantification of mouse mammary tumor virus structural proteins in hormone-induced mammary tumors of low mammary tumor mouse strains. Int J Cancer (1980) 0.84
Distribution and antibody-induced redistribution of a mammary tumor virus-induced and a normal antigen on the surface of mouse leukemia cells. J Natl Cancer Inst (1975) 0.83
Patching up Hedgehog. Nature (1996) 0.82
Autogenous antibodies against the murine mammary tumor virus in strains of mice with low incidences of mammary tumors. J Natl Cancer Inst (1979) 0.81
Antigenic modulation of mammary tumour virus envelope antigen or GR thymic lymphoma cells in relation to expressions of H-2, TL cell-surface antigens and THY1. Br J Cancer (1980) 0.80
Wnt meeting 1996. Biochim Biophys Acta (1997) 0.79
Differential requirements for segment polarity genes in wingless signaling. Mech Dev (1995) 0.79
Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea. Mol Cell Biol (1986) 0.75
Highlights of the 1998 Wnt meeting, Cambridge, MA, January 9-11. Biochim Biophys Acta (1998) 0.75
Localization of the oncogene c-Ha-ras1 outside the aniridia-Wilms' tumor-associated deletion of chromosome 11(del 11p13) using somatic cell hybrids. Cancer Genet Cytogenet (1985) 0.75
H-2L locus: alleles, products, and specificities. Transplant Proc (1979) 0.75