Published in Mol Biosyst on October 12, 2009
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Single-cell multiplex gene detection and sequencing with microfluidically generated agarose emulsions. Angew Chem Int Ed Engl (2011) 1.06
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Influences of electric field on living cells in a charged water-in-oil droplet under electrophoretic actuation. Biomicrofluidics (2011) 0.87
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Controlling droplet incubation using close-packed plug flow. Biomicrofluidics (2011) 0.82
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Ultrahigh-throughput-directed enzyme evolution by absorbance-activated droplet sorting (AADS). Proc Natl Acad Sci U S A (2016) 0.75
Enrichment of mutations in multiple DNA sequences using COLD-PCR in emulsion. PLoS One (2012) 0.75
Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis. Nano Converg (2014) 0.75
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Picoliter cell lysate assays in microfluidic droplet compartments for directed enzyme evolution. Chem Biol (2012) 1.87
Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation. J Biol Chem (2006) 1.82
Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays. Lab Chip (2008) 1.59
Directed evolution of a gatekeeper domain in nonribosomal peptide synthesis. Chem Biol (2011) 1.45
Development of quantitative cell-based enzyme assays in microdroplets. Anal Chem (2008) 1.29
Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets. Anal Chem (2009) 1.19
What makes an enzyme promiscuous? Curr Opin Chem Biol (2010) 1.17
Controlling the retention of small molecules in emulsion microdroplets for use in cell-based assays. Anal Chem (2009) 1.13
Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments. J Am Chem Soc (2009) 1.11
An efficient, multiply promiscuous hydrolase in the alkaline phosphatase superfamily. Proc Natl Acad Sci U S A (2010) 1.07
An integrated device for monitoring time-dependent in vitro expression from single genes in picolitre droplets. Chembiochem (2008) 1.06
A double droplet trap system for studying mass transport across a droplet-droplet interface. Lab Chip (2010) 1.04
Microfluidic droplets: new integrated workflows for biological experiments. Curr Opin Chem Biol (2010) 1.03
A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site. Proc Natl Acad Sci U S A (2006) 1.00
Ultrarapid generation of femtoliter microfluidic droplets for single-molecule-counting immunoassays. ACS Nano (2013) 0.99
New genotype-phenotype linkages for directed evolution of functional proteins. Curr Opin Struct Biol (2005) 0.98
The human histone acetyltransferase P/CAF is a promiscuous histone propionyltransferase. Chembiochem (2008) 0.98
One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution. Anal Chem (2014) 0.98
An efficient method to assemble linear DNA templates for in vitro screening and selection systems. Nucleic Acids Res (2009) 0.98
Efficient catalytic promiscuity in an enzyme superfamily: an arylsulfatase shows a rate acceleration of 10(13) for phosphate monoester hydrolysis. J Am Chem Soc (2008) 0.98
Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes. J Am Chem Soc (2008) 0.97
An integrated cell culture lab on a chip: modular microdevices for cultivation of mammalian cells and delivery into microfluidic microdroplets. Lab Chip (2009) 0.97
Efficient catalytic promiscuity for chemically distinct reactions. Angew Chem Int Ed Engl (2009) 0.95
Removal of background signals from fluorescence thermometry measurements in PDMS microchannels using fluorescence lifetime imaging. Lab Chip (2009) 0.92
In vitro affinity screening of protein and peptide binders by megavalent bead surface display. Protein Eng Des Sel (2013) 0.89
A single mutation in the core domain of the lac repressor reduces leakiness. Microb Cell Fact (2013) 0.89
A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets. Lab Chip (2012) 0.88
Efficient, crosswise catalytic promiscuity among enzymes that catalyze phosphoryl transfer. Biochim Biophys Acta (2012) 0.88
Simultaneous measurement of reactions in microdroplets filled by concentration gradients. Lab Chip (2009) 0.88
Mapping the limits of substrate specificity of the adenylation domain of TycA. Chembiochem (2009) 0.86
A covalent chemical genotype-phenotype linkage for in vitro protein evolution. Chembiochem (2007) 0.86
A fully unsupervised compartment-on-demand platform for precise nanoliter assays of time-dependent steady-state enzyme kinetics and inhibition. Anal Chem (2013) 0.85
An optimized ATP/PP(i)-exchange assay in 96-well format for screening of adenylation domains for applications in combinatorial biosynthesis. Biotechnol J (2007) 0.83
Droplets as reaction compartments for protein nanotechnology. Methods Mol Biol (2013) 0.82
Controlling the contents of microdroplets by exploiting the permeability of PDMS. Lab Chip (2011) 0.82
Kinetic analysis of beta-phosphoglucomutase and its inhibition by magnesium fluoride. J Am Chem Soc (2009) 0.82
Interfacing microwells with nanoliter compartments: a sampler generating high-resolution concentration gradients for quantitative biochemical analyses in droplets. Anal Chem (2014) 0.81
SNAP display: in vitro protein evolution in microdroplets. Methods Mol Biol (2012) 0.81
Peptide dendrimer/lipid hybrid systems are efficient DNA transfection reagents: structure--activity relationships highlight the role of charge distribution across dendrimer generations. ACS Nano (2013) 0.81
Flexibility and reactivity in promiscuous enzymes. Chembiochem (2013) 0.81
Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice. PLoS One (2013) 0.81
Monitoring a reaction at submillisecond resolution in picoliter volumes. Anal Chem (2011) 0.81
One-pot deracemization of sec-alcohols: enantioconvergent enzymatic hydrolysis of alkyl sulfates using stereocomplementary sulfatases. Angew Chem Int Ed Engl (2013) 0.81
Polyethylene imine derivatives ('synzymes') accelerate phosphate transfer in the absence of metal. J Am Chem Soc (2007) 0.80
SNAP dendrimers: multivalent protein display on dendrimer-like DNA for directed evolution. Chembiochem (2011) 0.80
Fluid phase endocytosis contributes to transfection of DNA by PEI-25. Mol Ther (2009) 0.80
Relating chemical and biological diversity space: a tunable system for efficient gene transfection. Chembiochem (2008) 0.80
SNAP display - an in vitro method for the selection of protein binders. Curr Pharm Des (2013) 0.79
Combining medium effects and cofactor catalysis: metal-coordinated synzymes accelerate phosphate transfer by 10(8). Chemistry (2009) 0.79
Isothermal DNA amplification using the T4 replisome: circular nicking endonuclease-dependent amplification and primase-based whole-genome amplification. Nucleic Acids Res (2010) 0.79
Biochemistry: Enzymes under the nanoscope. Nature (2008) 0.78
Kinetic and computational evidence for an intermediate in the hydrolysis of sulfonate esters. Org Biomol Chem (2012) 0.77
Molecular recognition of DNA by rigid [N]-polynorbornane-derived bifunctional intercalators: synthesis and evaluation of their binding properties. J Med Chem (2007) 0.77
Just (protein) engineering? Curr Opin Struct Biol (2013) 0.77
Hitting a moving target?--Understanding how conformational diversity impacts enzymatic catalysis. Curr Opin Chem Biol (2010) 0.76
USER friendly DNA recombination (USERec): gene library construction requiring minimal sequence homology. Methods Mol Biol (2014) 0.75
Directed evolution of a histone acetyltransferase--enhancing thermostability, whilst maintaining catalytic activity and substrate specificity. FEBS J (2008) 0.75
peri-Dimethylamino substituent effects on proton transfer at carbon in α-naphthylacetate esters: a model for mandelate racemase. Org Biomol Chem (2011) 0.75
European Symposium of Bio-Organic Chemistry 2003 (ESBOC): the evolution of catalysis. Chembiochem (2004) 0.75
Assembling linear DNA templates for in vitro transcription and translation. Methods Mol Biol (2012) 0.75
From fascination to function. Curr Opin Biotechnol (2011) 0.75