Published in J Neurochem on December 01, 2009
ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels. J Neurochem (2011) 1.52
The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. J Neuroimmune Pharmacol (2012) 1.13
Gap junctions in inherited human disorders of the central nervous system. Biochim Biophys Acta (2011) 1.05
Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. Front Pharmacol (2013) 1.02
Bmcc1s, a novel brain-isoform of Bmcc1, affects cell morphology by regulating MAP6/STOP functions. PLoS One (2012) 0.84
Cannabinoid modulation of neuroinflammatory disorders. Curr Neuropharmacol (2012) 0.80
Prenatal nicotine exposure enhances Cx43 and Panx1 unopposed channel activity in brain cells of adult offspring mice fed a high-fat/cholesterol diet. Front Cell Neurosci (2014) 0.78
The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α. J Biol Chem (2012) 0.78
Connexins and their channels in inflammation. Crit Rev Biochem Mol Biol (2016) 0.77
Upregulation of connexins 30 and 32 gap junctions in rat hippocampus at transcription level by chronic central injection of lipopolysaccharide. Iran Biomed J (2012) 0.75
Intracerebroventricular injection of lipopolysaccharide increases gene expression of connexin32 gap junction in rat hippocampus. Basic Clin Neurosci (2013) 0.75
Connexins and Pannexins: New Insights into Microglial Functions and Dysfunctions. Front Mol Neurosci (2016) 0.75
Connexin Channels at the Glio-Vascular Interface: Gatekeepers of the Brain. Neurochem Res (2017) 0.75
Astroglial metabolic networks sustain hippocampal synaptic transmission. Science (2008) 3.49
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proc Natl Acad Sci U S A (2001) 3.17
Gating and regulation of connexin 43 (Cx43) hemichannels. Proc Natl Acad Sci U S A (2003) 2.79
New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci (2003) 2.25
Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential. Hum Mol Genet (2003) 2.17
Astrocyte calcium waves: what they are and what they do. Glia (2006) 2.17
Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia. J Neurosci (2007) 2.06
S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: induction by oxidant stress and reversal by reducing agents. Proc Natl Acad Sci U S A (2006) 1.74
Astroglial networks scale synaptic activity and plasticity. Proc Natl Acad Sci U S A (2011) 1.56
Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Res Brain Res Rev (2004) 1.54
ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels. J Neurochem (2011) 1.52
TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses. J Immunol (2003) 1.46
Control and plasticity of intercellular calcium waves in astrocytes: a modeling approach. J Neurosci (2002) 1.37
Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxid Redox Signal (2009) 1.34
Cell membrane permeabilization via connexin hemichannels in living and dying cells. Exp Cell Res (2010) 1.34
Deletion of astroglial connexins weakens the blood-brain barrier. J Cereb Blood Flow Metab (2012) 1.30
Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential. Proc Natl Acad Sci U S A (2007) 1.30
FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels. Proc Natl Acad Sci U S A (2010) 1.30
Amyloid β-induced death in neurons involves glial and neuronal hemichannels. J Neurosci (2011) 1.28
Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: potentiation by beta-amyloid. FASEB J (2006) 1.28
Electrical and chemical transmission between striatal GABAergic output neurones in rat brain slices. J Physiol (2004) 1.25
Gap junction-mediated astrocytic networks in the mouse barrel cortex. J Neurosci (2008) 1.21
Expression of connexins during differentiation and regeneration of skeletal muscle: functional relevance of connexin43. J Cell Sci (2004) 1.19
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala. FASEB J (2012) 1.17
A role of the (pro)renin receptor in neuronal cell differentiation. Am J Physiol Regul Integr Comp Physiol (2009) 1.16
Connexin hemichannel composition determines the FGF-1-induced membrane permeability and free [Ca2+]i responses. Mol Biol Cell (2008) 1.15
Currently used methods for identification and characterization of hemichannels. Cell Commun Adhes (2008) 1.13
The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. J Neuroimmune Pharmacol (2012) 1.13
Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective. Mol Cell Neurosci (2010) 1.12
Glucose increases intracellular free Ca(2+) in tanycytes via ATP released through connexin 43 hemichannels. Glia (2011) 1.11
Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Res (2012) 1.10
S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK. Eur J Neurosci (2006) 1.07
Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization. Am J Physiol Cell Physiol (2010) 1.05
Glucose metabolism and proliferation in glia: role of astrocytic gap junctions. J Neurochem (2006) 1.04
Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. Front Pharmacol (2013) 1.02
Metabolic inhibition increases activity of connexin-32 hemichannels permeable to Ca2+ in transfected HeLa cells. Am J Physiol Cell Physiol (2009) 1.02
Lysosomes are the major vesicular compartment undergoing Ca2+-regulated exocytosis from cortical astrocytes. J Neurosci (2008) 1.01
Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes. Glia (2008) 1.01
Identification of second messengers that induce expression of functional gap junctions in microglia cultured from newborn rats. Brain Res (2002) 1.01
Functional gap junctions facilitate melanoma antigen transfer and cross-presentation between human dendritic cells. J Immunol (2007) 1.01
Connexin-based intercellular communication and astrocyte heterogeneity. Brain Res (2012) 1.00
Gap junction intercellular communication mediated by connexin43 in astrocytes is essential for their resistance to oxidative stress. J Biol Chem (2013) 0.99
Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo. Am J Physiol Heart Circ Physiol (2008) 0.97
Understanding risk factors for Alzheimer's disease: interplay of neuroinflammation, connexin-based communication and oxidative stress. Arch Med Res (2012) 0.95
Plasticity of astroglial networks in olfactory glomeruli. Proc Natl Acad Sci U S A (2011) 0.94
Neurons set the tone of gap junctional communication in astrocytic networks. Neurochem Int (2004) 0.94
De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy. Proc Natl Acad Sci U S A (2013) 0.92
Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Mol Biol Cell (2012) 0.92
Detecting fluorescent protein expression and co-localisation on single secretory vesicles with linear spectral unmixing. Eur Biophys J (2006) 0.92
Connexin43 is involved in the effect of endothelin-1 on astrocyte proliferation and glucose uptake. Glia (2009) 0.92
Glial hemichannels and their involvement in aging and neurodegenerative diseases. Rev Neurosci (2012) 0.91
Shapes of astrocyte networks in the juvenile brain. Neuron Glia Biol (2006) 0.91
Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion. J Membr Biol (2007) 0.90
Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins. Hum Mol Genet (2009) 0.90
The formation of skeletal muscle myotubes requires functional membrane receptors activated by extracellular ATP. Brain Res Brain Res Rev (2004) 0.89
Regulation of hepatic connexins in cholestasis: possible involvement of Kupffer cells and inflammatory mediators. Am J Physiol Gastrointest Liver Physiol (2002) 0.89
Gap junctions at the dendritic cell-T cell interface are key elements for antigen-dependent T cell activation. J Immunol (2009) 0.89
Regulation of intercellular calcium signaling through calcium interactions with connexin-based channels. Adv Exp Med Biol (2012) 0.88
ATP is required and advances cytokine-induced gap junction formation in microglia in vitro. Mediators Inflamm (2013) 0.88
FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7). J Cell Physiol (2013) 0.88
Inflammatory conditions induce gap junctional communication between rat Kupffer cells both in vivo and in vitro. Cell Immunol (2007) 0.87
Association of Caspr/paranodin with tumour suppressor schwannomin/merlin and beta1 integrin in the central nervous system. J Neurochem (2003) 0.87
Presence and importance of connexin43 during myogenesis. Cell Commun Adhes (2003) 0.87
Cation permeation through connexin 43 hemichannels is cooperative, competitive and saturable with parameters depending on the permeant species. Biochem Biophys Res Commun (2011) 0.87
Activation of human polymorphonuclear cells induces formation of functional gap junctions and expression of connexins. Med Sci Monit (2002) 0.86
Functioning of cx43 hemichannels demonstrated by single channel properties. Cell Commun Adhes (2003) 0.86
Spontaneous synaptic activity is primarily GABAergic in vestibular nucleus neurons of the chick embryo. J Neurophysiol (2003) 0.86
Reduced connexin43 expression correlates with c-Src activation, proliferation, and glucose uptake in reactive astrocytes after an excitotoxic insult. Glia (2012) 0.85
Connexin- and pannexin-based channels in normal skeletal muscles and their possible role in muscle atrophy. J Membr Biol (2012) 0.85
Glial connexin expression and function in the context of Alzheimer's disease. Biochim Biophys Acta (2011) 0.85