Published in Acta Crystallogr D Biol Crystallogr on December 21, 2009
Stereochemical restraints revisited: how accurate are refinement targets and how much should protein structures be allowed to deviate from them? Acta Crystallogr D Biol Crystallogr (2007) 4.51
Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage. Mol Cell (2005) 4.11
Stabilizing isopeptide bonds revealed in gram-positive bacterial pilus structure. Science (2007) 4.10
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat Struct Mol Biol (2005) 2.50
The DCX-domain tandems of doublecortin and doublecortin-like kinase. Nat Struct Biol (2003) 2.22
A crystallographic study of bright far-red fluorescent protein mKate reveals pH-induced cis-trans isomerization of the chromophore. J Biol Chem (2008) 1.98
The crystal structure of the endothelial protein C receptor and a bound phospholipid. J Biol Chem (2002) 1.84
The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds. Proc Natl Acad Sci U S A (2009) 1.79
Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alpha. J Biol Chem (2003) 1.79
Triclinic lysozyme at 0.65 A resolution. Acta Crystallogr D Biol Crystallogr (2007) 1.77
Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease. J Biol Chem (2004) 1.74
Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures. FEBS J (2007) 1.70
A flexible and economical medium-throughput strategy for protein production and crystallization. Acta Crystallogr D Biol Crystallogr (2005) 1.67
The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance. J Mol Biol (2003) 1.65
B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins (2006) 1.47
The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle. Structure (2004) 1.45
Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes. J Biol Chem (2009) 1.45
Dealing with iron: common structural principles in proteins that transport iron and heme. Proc Natl Acad Sci U S A (2003) 1.44
Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis. Proc Natl Acad Sci U S A (2004) 1.44
Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity. Structure (2010) 1.33
The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site. J Biol Chem (2003) 1.33
Intramolecular isopeptide bonds: protein crosslinks built for stress? Trends Biochem Sci (2010) 1.31
Structural effects of radiation damage and its potential for phasing. Acta Crystallogr D Biol Crystallogr (2004) 1.28
The TB structural genomics consortium: providing a structural foundation for drug discovery. Curr Drug Targets Infect Disord (2002) 1.28
The Three-dimensional structure of a superantigen-like protein, SET3, from a pathogenicity island of the Staphylococcus aureus genome. J Biol Chem (2002) 1.28
The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily. J Bacteriol (2009) 1.27
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism. Proc Natl Acad Sci U S A (2006) 1.27
Numerology versus reality: a voice in a recent dispute. Acta Crystallogr D Biol Crystallogr (2007) 1.26
PDZ tandem of human syntenin: crystal structure and functional properties. Structure (2003) 1.21
Structure and assembly of Gram-positive bacterial pili: unique covalent polymers. Curr Opin Struct Biol (2012) 1.21
The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution. Acta Crystallogr D Biol Crystallogr (2002) 1.21
Radiation-induced site-specific damage of mercury derivatives: phasing and implications. Acta Crystallogr D Biol Crystallogr (2005) 1.18
Aminoglycoside antibiotic resistance by enzymatic deactivation. Curr Drug Targets Infect Disord (2002) 1.17
Locating the anomalous scatterer substructures in halide and sulfur phasing. Acta Crystallogr D Biol Crystallogr (2002) 1.17
Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring. J Biol Chem (2010) 1.16
A new Gateway vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis. Protein Expr Purif (2007) 1.14
Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation. Structure (2005) 1.13
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding. J Biol Chem (2008) 1.12
Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin. J Mol Biol (2005) 1.11
The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase. J Bacteriol (2006) 1.11
Phasing on anomalous signal of sulfurs: what is the limit? Acta Crystallogr D Biol Crystallogr (2003) 1.10
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system. Protein Expr Purif (2007) 1.10
Structural basis for phototoxicity of the genetically encoded photosensitizer KillerRed. J Biol Chem (2009) 1.09
(2R)-8-Benzyl-2-[(S)-hy-droxy(phen-yl)meth-yl]-8-aza-bicyclo-[3.2.1]octan-3-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.09
The crystal structure of Rv1347c, a putative antibiotic resistance protein from Mycobacterium tuberculosis, reveals a GCN5-related fold and suggests an alternative function in siderophore biosynthesis. J Biol Chem (2005) 1.08
The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition. Mol Microbiol (2007) 1.07
Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon. Proteins (2008) 1.07
Understanding blue-to-red conversion in monomeric fluorescent timers and hydrolytic degradation of their chromophores. J Am Chem Soc (2010) 1.07
Phase determination using halide ions. Methods Mol Biol (2007) 1.06
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. J Mol Biol (2005) 1.04
Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis. J Mol Biol (2004) 1.04
Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo. Endocrinology (2004) 1.04
The TB Structural Genomics Consortium: a decade of progress. Tuberculosis (Edinb) (2011) 1.03
Lactoferrin and iron: structural and dynamic aspects of binding and release. Biometals (2004) 1.03
Radiation-damage-induced phasing with anomalous scattering: substructure solution and phasing. Acta Crystallogr D Biol Crystallogr (2004) 1.03
Roles of minor pilin subunits Spy0125 and Spy0130 in the serotype M1 Streptococcus pyogenes strain SF370. J Bacteriol (2010) 1.03
High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A. Nucleic Acids Res (2011) 1.02
Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins. J Mol Biol (2007) 1.02
Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects. J Biol Chem (2008) 1.02
Metabolic engineering of cofactor F420 production in Mycobacterium smegmatis. PLoS One (2010) 1.01
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Biol Chem (2010) 1.00
Citations in supplementary material. Acta Crystallogr D Biol Crystallogr (2010) 1.00
Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination. FEBS J (2013) 0.99
Structure and function of GlmU from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr (2009) 0.99
Rotational order-disorder structure of fluorescent protein FP480. Acta Crystallogr D Biol Crystallogr (2009) 0.99
Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation. Biochemistry (2003) 0.99
Refined crystal structures of red and green fluorescent proteins from the button polyp Zoanthus. Acta Crystallogr D Biol Crystallogr (2007) 0.99
Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin. Proc Natl Acad Sci U S A (2013) 0.98
Crystal structure of Spy0129, a Streptococcus pyogenes class B sortase involved in pilus assembly. PLoS One (2011) 0.98
Structural origins of the functional divergence of human insulin-like growth factor-I and insulin. Biochemistry (2002) 0.97
Crystal structure of XMRV protease differs from the structures of other retropepsins. Nat Struct Mol Biol (2011) 0.97
Structure of DraD invasin from uropathogenic Escherichia coli: a dimer with swapped beta-tails. Acta Crystallogr D Biol Crystallogr (2006) 0.96
Atomic-resolution crystal structure of the antiviral lectin scytovirin. Protein Sci (2007) 0.96
Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry. Biopolymers (2009) 0.95
The laminin-binding protein Lbp from Streptococcus pyogenes is a zinc receptor. J Bacteriol (2009) 0.95
Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation. Mol Microbiol (2014) 0.95
Atomic resolution structure of Erwinia chrysanthemi L-asparaginase. Acta Crystallogr D Biol Crystallogr (2002) 0.95
Structural model for covalent adhesion of the Streptococcus pyogenes pilus through a thioester bond. J Biol Chem (2013) 0.95
The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism. Structure (2004) 0.94
Structure of the full-length major pilin from Streptococcus pneumoniae: implications for isopeptide bond formation in gram-positive bacterial pili. PLoS One (2011) 0.93
Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Mol Biol (2012) 0.92
Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes. Biochemistry (2009) 0.92
Structural basis for bathochromic shift of fluorescence in far-red fluorescent proteins eqFP650 and eqFP670. Acta Crystallogr D Biol Crystallogr (2012) 0.92
Defining the potassium binding region in an apple terpene synthase. J Biol Chem (2009) 0.92
In defence of our science--validation now! Acta Crystallogr D Biol Crystallogr (2010) 0.92
Crystal structure of a putative methyltransferase from Mycobacterium tuberculosis: misannotation of a genome clarified by protein structural analysis. J Bacteriol (2003) 0.91
Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms. Acta Crystallogr D Biol Crystallogr (2005) 0.91
Histidine phosphorylation in biological systems. Biochim Biophys Acta (2007) 0.91
High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon. Biochemistry (2007) 0.91
A structural perspective on lactoferrin function. Biochem Cell Biol (2012) 0.91
Crystallographic study of red fluorescent protein eqFP578 and its far-red variant Katushka reveals opposite pH-induced isomerization of chromophore. Protein Sci (2011) 0.91
The quality and validation of structures from structural genomics. Methods Mol Biol (2014) 0.90
On the reproducibility of protein crystal structures: five atomic resolution structures of trypsin. Acta Crystallogr D Biol Crystallogr (2013) 0.90
Structure of a Bacillus halmapalus family 13 alpha-amylase, BHA, in complex with an acarbose-derived nonasaccharide at 2.1 A resolution. Acta Crystallogr D Biol Crystallogr (2005) 0.89
Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain. FEBS J (2006) 0.89
Novel fold of VirA, a type III secretion system effector protein from Shigella flexneri. Protein Sci (2008) 0.89
To scavenge or not to scavenge: that is the question. Acta Crystallogr D Biol Crystallogr (2009) 0.89
Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP. Acta Crystallogr D Biol Crystallogr (2008) 0.89