Published in Chem Biol Interact on January 11, 2010
Butyrylcholinesterase is associated with β-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease. J Neuropathol Exp Neurol (2012) 0.95
Whole-exome sequencing to decipher the genetic heterogeneity of hearing loss in a Chinese family with deaf by deaf mating. PLoS One (2014) 0.85
Xylans Provide the Structural Driving Force for Mucilage Adhesion to the Arabidopsis Seed Coat. Plant Physiol (2016) 0.82
Three-step procedure for preparation of pure Bacillus altitudinis ribonuclease. FEBS Open Bio (2016) 0.80
Evolution of neurodegeneration. Curr Biol (2012) 0.79
Characterization of a novel BCHE "silent" allele: point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium. PLoS One (2014) 0.78
Perioperative dynamics and significance of amino acid profiles in patients with cancer. J Transl Med (2015) 0.77
It all starts at the ends: multifaceted involvement of C- and N-terminally modified cholinesterases in Alzheimer's disease. Rambam Maimonides Med J (2010) 0.75
Function of alternative splicing. Gene (2004) 5.95
Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression. Bioinformatics (2004) 2.47
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity (2009) 2.33
RACK1 has the nerve to act: structure meets function in the nervous system. Prog Neurobiol (2006) 1.56
Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO Mol Med (2013) 1.54
Chronic cholinergic imbalances promote brain diffusion and transport abnormalities. FASEB J (2005) 1.50
A network-based method for predicting disease-causing genes. J Comput Biol (2009) 1.49
MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leuk Res (2005) 1.49
Virtues and woes of AChE alternative splicing in stress-related neuropathologies. Trends Neurosci (2006) 1.45
Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science (2002) 1.39
Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol (2002) 1.28
Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. J Biol Chem (2009) 1.23
Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products. J Biol Chem (2004) 1.20
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proc Natl Acad Sci U S A (2010) 1.20
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proc Natl Acad Sci U S A (2012) 1.16
Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci (2009) 1.16
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study. Proc Natl Acad Sci U S A (2004) 1.09
Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. EMBO Mol Med (2012) 1.09
The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. FASEB J (2003) 1.08
Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci U S A (2006) 1.08
Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell Tissue Res (2006) 1.07
Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. Proc Natl Acad Sci U S A (2002) 1.07
Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain (2007) 1.06
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol (2005) 1.05
Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase. Plant Biotechnol J (2010) 1.05
Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortality. Mol Med (2010) 1.04
Pre-mRNA splicing modulations in senescence. Aging Cell (2002) 1.03
Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements. Eur J Biochem (2002) 1.02
Purification of transgenic plant-derived recombinant human acetylcholinesterase-R. Chem Biol Interact (2005) 0.98
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. PLoS One (2008) 0.98
MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease. Inflamm Bowel Dis (2013) 0.97
Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes. Neurodegener Dis (2011) 0.96
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice. Curr Alzheimer Res (2005) 0.96
Gene-environment interactions in sporadic Parkinson's disease. J Neurochem (2006) 0.95
Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia (2012) 0.95
Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Front Mol Neurosci (2013) 0.94
The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology. J Biol Chem (2009) 0.94
Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease. J Mol Neurosci (2013) 0.93
Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease. FASEB J (2005) 0.93
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses. J Immunol (2006) 0.93
Global coevolution of human microRNAs and their target genes. Mol Biol Evol (2014) 0.93
Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patients. J Neuroimmunol (2008) 0.92
Erythropoietin attenuates hyperoxia-induced oxidative stress in the developing rat brain. Brain Behav Immun (2009) 0.91
The stress-associated acetylcholinesterase variant AChE-R is expressed in human CD34(+) hematopoietic progenitors and its C-terminal peptide ARP promotes their proliferation. Exp Hematol (2002) 0.91
Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults. Toxicology (2006) 0.91
Cholinesterase-Targeting microRNAs Identified in silico Affect Specific Biological Processes. Front Mol Neurosci (2011) 0.90
Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions. Front Mol Neurosci (2012) 0.90
Heterogeneous nuclear ribonucleoprotein A1 in health and neurodegenerative disease: from structural insights to post-transcriptional regulatory roles. Mol Cell Neurosci (2012) 0.90
Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma "readthrough" acetylcholinesterase. J Mol Neurosci (2003) 0.89
Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome. PLoS One (2011) 0.89
RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons. Neurodegener Dis (2005) 0.89
Antisense treatment for myasthenia gravis: experience with monarsen. Ann N Y Acad Sci (2008) 0.88
Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis. Front Mol Neurosci (2012) 0.88
Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation. Curr Alzheimer Res (2012) 0.88
Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development. Cereb Cortex (2005) 0.88
Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath. FASEB J (2007) 0.88
Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex. J Neurosci (2013) 0.88
Complex regulation of acetylcholinesterase gene expression in human brain tumors. Oncogene (2002) 0.88
Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load. Curr Alzheimer Res (2013) 0.87
Inherited and acquired interactions between ACHE and PON1 polymorphisms modulate plasma acetylcholinesterase and paraoxonase activities. J Neurochem (2005) 0.87
Runx1/AML1 in leukemia: disrupted association with diverse protein partners. Leuk Res (2002) 0.87
AChE and RACK1 promote the anti-inflammatory properties of fluoxetine. J Mol Neurosci (2013) 0.87
Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons. J Neurosci (2004) 0.87
Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis. Blood (2005) 0.87
The thymic theme of acetylcholinesterase splice variants in myasthenia gravis. Blood (2007) 0.86
CREB regulates AChE-R-induced proliferation of human glioblastoma cells. Neoplasia (2004) 0.86
Predictors for poststroke outcomes: the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study protocol. Int J Stroke (2011) 0.86
Cellular stress reactions as putative cholinergic links in Alzheimer's disease. Neurochem Res (2005) 0.85
Modulated splicing-associated gene expression in P19 cells expressing distinct acetylcholinesterase splice variants. J Neurochem (2006) 0.85
microRNAs in nociceptive circuits as predictors of future clinical applications. Front Mol Neurosci (2013) 0.85
The structural basis of amyloid formation. Curr Alzheimer Res (2008) 0.85
Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations. Neurobiol Dis (2010) 0.84
Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways. Neurobiol Dis (2011) 0.84
Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure. FASEB J (2006) 0.84
Alternate AChE-R variants facilitate cellular metabolic activity and resistance to genotoxic stress through enolase and RACK1 interactions. Chem Biol Interact (2008) 0.83
Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays. PLoS One (2008) 0.83
The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice. Behav Brain Res (2008) 0.83
Translational control of recombinant human acetylcholinesterase accumulation in plants. BMC Biotechnol (2007) 0.82
A novel isoform of acetylcholinesterase exacerbates photoreceptors death after photic stress. Invest Ophthalmol Vis Sci (2007) 0.82
From brain to blood: alternative splicing evidence for the cholinergic basis of Mammalian stress responses. Ann N Y Acad Sci (2004) 0.82
Blood-cell-specific acetylcholinesterase splice variations under changing stimuli. Int J Dev Neurosci (2004) 0.81
Pro-apoptotic protein-protein interactions of the extended N-AChE terminus. J Neural Transm (Vienna) (2009) 0.80
Acetylcholinesterase modulates stress-induced motor responses through catalytic and noncatalytic properties. Biol Psychiatry (2006) 0.80
Butyrylcholinesterase interactions with amylin may protect pancreatic cells in metabolic syndrome. J Cell Mol Med (2011) 0.80
Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats. Eur J Neurosci (2008) 0.80
ARP, the cleavable C-terminal peptide of "readthrough" acetylcholinesterase, promotes neuronal development and plasticity. J Mol Neurosci (2006) 0.80
Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson's patients leukocytes. BMC Genomics (2013) 0.80
Neuromuscular therapeutics by RNA-targeted suppression of ACHE gene expression. Ann N Y Acad Sci (2006) 0.80
Cytokines and cholinergic signals co-modulate surgical stress-induced changes in mood and memory. Brain Behav Immun (2007) 0.79
Peripheral site acetylcholinesterase blockade induces RACK1-associated neuronal remodeling. Neurodegener Dis (2007) 0.79
Deep brain stimulation induces rapidly reversible transcript changes in Parkinson's leucocytes. J Cell Mol Med (2012) 0.79
Acetylcholinesterase variants in Alzheimer's disease: from neuroprotection to programmed cell death. Neurodegener Dis (2010) 0.79
Tissue distribution of cholinesterases and anticholinesterases in native and transgenic tomato plants. Plant Mol Biol (2004) 0.79
Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling. J Cell Mol Med (2012) 0.79
Adaptive alternative splicing correlates with less environmental risk of parkinsonism. Neurodegener Dis (2011) 0.78
Impaired hippocampal plasticity and errors in cognitive performance in mice with maladaptive AChE splice site selection. Eur J Neurosci (2007) 0.78
Stereotactic injection of microRNA-expressing lentiviruses to the mouse hippocampus ca1 region and assessment of the behavioral outcome. J Vis Exp (2013) 0.78