Published in Proc Natl Acad Sci U S A on March 15, 1991
Tissue distribution and subcellular localization of mammalian myosin I. J Cell Biol (1992) 2.09
Immunochemical analysis of kinesin light chain function. Mol Biol Cell (1997) 1.72
Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome. Mol Cell Biol (1995) 1.62
Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules. J Cell Biol (1992) 1.36
Dissociation and Reassembly of the Vacuolar H-ATPase Complex from Oat Roots. Plant Physiol (1992) 1.35
Dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll. Mol Cell Biol (1994) 1.28
Antisense ribosomes: rRNA as a vehicle for antisense RNAs. Proc Natl Acad Sci U S A (1996) 1.22
Calmodulin and calmodulin-binding proteins in hair bundles. Proc Natl Acad Sci U S A (1993) 1.21
Intermolecular cleavage by UmuD-like mutagenesis proteins. Proc Natl Acad Sci U S A (1998) 1.21
Transcriptional activation by the parvoviral nonstructural protein NS-1 is mediated via a direct interaction with Sp1. Mol Cell Biol (1995) 1.20
Cryptosporidium parvum apical complex glycoprotein CSL contains a sporozoite ligand for intestinal epithelial cells. Infect Immun (1999) 0.99
Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo. EMBO J (1993) 0.92
Dufulin activates HrBP1 to produce antiviral responses in tobacco. PLoS One (2012) 0.85
Monoclonal antibodies against recombinant Der f 3 reveal localization of Der f 3 in the gut and faecal pellets of Dermatophagoides farinae. Exp Appl Acarol (2010) 0.77
Neural regulation of the formation of skeletal muscle phosphorylase kinase holoenzyme in adult and developing rat muscle. Biochem J (1997) 0.76
Suppression of proline-directed protein kinase F(A) expression inhibits the growth of human chronic myeloid leukaemia cells. Br J Cancer (2000) 0.75
Effect of human and bovine serum albumin on kinetic chemiluminescence of Mn (III)-Tetrakis (4-sulfonatophenyl) porphyrin-luminol-hydrogen peroxide system. ScientificWorldJournal (2012) 0.75
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem (1981) 71.15
The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Biochem J (1973) 22.93
A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots. Anal Biochem (1984) 22.53
An enzymic method for the trace iodination of immunoglobulins and other proteins. Biochem J (1969) 14.06
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell (1985) 13.73
A novel brain ATPase with properties expected for the fast axonal transport motor. Nature (1985) 5.30
Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line. Proc Natl Acad Sci U S A (1988) 3.19
Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes. Nature (1980) 2.99
Protein contaminants of sodium dodecyl sulfate-polyacrylamide gels. Anal Biochem (1983) 2.47
Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. J Cell Biol (1989) 2.38
Phosphorylation determines two distinct species of Tau in the central nervous system. Cell Motil Cytoskeleton (1987) 2.18
Protein biotinylation. Methods Enzymol (1990) 1.89
A SPECTROPHOTOMETRIC ASSAY FOR AVIDIN AND BIOTIN BASED ON BINDING OF DYES BY AVIDIN. Biochem J (1965) 1.57
Identification of surface proteins on bovine leukocytes by a biotin-avidin protein blotting technique. J Immunol Methods (1985) 1.55
Protein complement of rod outer segments of frog retina. Biochemistry (1986) 1.54
High-purity isolation of bullfrog hair bundles and subcellular and topological localization of constituent proteins. J Cell Biol (1991) 1.48
Sensitive visualization of antigen-antibody reactions in dot and blot immune overlay assays with immunogold and immunogold/silver staining. J Immunol Methods (1984) 1.47
Light-based detection of biomolecules. Nature (1990) 1.31
1,2-dioxetanes: novel chemiluminescent enzyme substrates. Applications to immunoassays. J Biolumin Chemilumin (1989) 1.26
Quantitative electrotransfer of proteins from sodium dodecyl sulfate-polyacrylamide gels onto positively charged nylon membranes. Anal Biochem (1987) 1.19
Chemiluminescence lights up. Nature (1989) 1.17
Chemiluminescent substrates for alkaline phosphatase: application to ultrasensitive enzyme-linked immunoassays and DNA probes. Clin Chem (1989) 1.17
Immunogold for detection of antigen on nitrocellulose paper. Anal Biochem (1984) 1.06
Imaging of DNA sequences with chemiluminescence. Proc Natl Acad Sci U S A (1990) 1.04
Analysis of differences between coomassie blue stain and silver stain procedures in polyacrylamide gels: conditions for the detection of calmodulin and troponin C. Anal Biochem (1983) 1.01
Transducin activation in electropermeabilized frog rod outer segments is highly amplified, and a portion equivalent to phosphodiesterase remains membrane-bound. J Biol Chem (1990) 0.97
Rapid and sensitive detection of DNA in Southern blots with chemiluminescence. Biotechniques (1990) 0.88
Immunochemical detection of proteins biotinylated on nitrocellulose replicas. J Immunol Methods (1986) 0.81
Chemically modified porous silica gel as a bioadsorbent and a biocatalyst. Anal Biochem (1979) 0.78
Electrophoretic transfer of viral proteins to nitrocellulose sheets and detection with peroxidase-bound lectins and protein A. J Immunol Methods (1983) 0.77
Movement of microtubules by single kinesin molecules. Nature (1989) 7.31
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell (2000) 5.73
Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli. Proc Natl Acad Sci U S A (1977) 5.14
Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell. Neuron (1988) 5.04
Kinetics of the receptor current in bullfrog saccular hair cells. J Neurosci (1983) 4.62
Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells. J Neurosci (1990) 4.62
Ionic basis of the receptor potential in a vertebrate hair cell. Nature (1979) 4.22
Mechanical relaxation of the hair bundle mediates adaptation in mechanoelectrical transduction by the bullfrog's saccular hair cell. Proc Natl Acad Sci U S A (1987) 4.02
Voltage- and ion-dependent conductances in solitary vertebrate hair cells. Nature (1983) 3.44
Essential nonlinearities in hearing. Phys Rev Lett (2000) 3.02
Ca2+ current-driven nonlinear amplification by the mammalian cochlea in vitro. Nat Neurosci (2005) 3.00
Adaptation of mechanoelectrical transduction in hair cells of the bullfrog's sacculus. J Neurosci (1987) 2.98
Active hair-bundle movements can amplify a hair cell's response to oscillatory mechanical stimuli. Proc Natl Acad Sci U S A (1999) 2.91
Extracellular current flow and the site of transduction by vertebrate hair cells. J Neurosci (1982) 2.82
Mechanoelectrical transduction by hair cells. Annu Rev Biophys Biophys Chem (1988) 2.71
Spontaneous oscillation by hair bundles of the bullfrog's sacculus. J Neurosci (2003) 2.61
Gap junctions between electrotonically coupled cells in tissue culture and in brown fat. Proc Natl Acad Sci U S A (1971) 2.59
The transduction channel of hair cells from the bull-frog characterized by noise analysis. J Physiol (1986) 2.47
A model for amplification of hair-bundle motion by cyclical binding of Ca2+ to mechanoelectrical-transduction channels. Proc Natl Acad Sci U S A (1998) 2.42
Mechanical properties of sensory hair bundles are reflected in their Brownian motion measured with a laser differential interferometer. Proc Natl Acad Sci U S A (1989) 2.38
Transfer characteristics of the hair cell's afferent synapse. Proc Natl Acad Sci U S A (2006) 2.33
Negative hair-bundle stiffness betrays a mechanism for mechanical amplification by the hair cell. Proc Natl Acad Sci U S A (2000) 2.30
Rapid, active hair bundle movements in hair cells from the bullfrog's sacculus. J Neurosci (1996) 2.29
Ultrastructural correlates of mechanoelectrical transduction in hair cells of the bullfrog's internal ear. Cold Spring Harb Symp Quant Biol (1990) 2.19
Analysis of the microphonic potential of the bullfrog's sacculus. J Neurosci (1983) 2.15
Plasma membrane Ca2+-ATPase extrudes Ca2+ from hair cell stereocilia. J Neurosci (1998) 2.14
Coherent motion of stereocilia assures the concerted gating of hair-cell transduction channels. Nat Neurosci (2006) 2.11
Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nat Genet (1998) 2.04
Localization of the hair cell's transduction channels at the hair bundle's top by iontophoretic application of a channel blocker. Neuron (1991) 2.01
Blockage of the transduction channels of hair cells in the bullfrog's sacculus by aminoglycoside antibiotics. Hear Res (1989) 2.00
Compressive nonlinearity in the hair bundle's active response to mechanical stimulation. Proc Natl Acad Sci U S A (2001) 1.97
Comparison of a hair bundle's spontaneous oscillations with its response to mechanical stimulation reveals the underlying active process. Proc Natl Acad Sci U S A (2001) 1.96
Stereocilia mediate transduction in vertebrate hair cells (auditory system/cilium/vestibular system). Proc Natl Acad Sci U S A (1979) 1.95
The unitary event underlying multiquantal EPSCs at a hair cell's ribbon synapse. J Neurosci (2009) 1.93
Clustering of Ca2+ channels and Ca(2+)-activated K+ channels at fluorescently labeled presynaptic active zones of hair cells. Proc Natl Acad Sci U S A (1994) 1.89
Regulation of free Ca2+ concentration in hair-cell stereocilia. J Neurosci (1998) 1.88
Detection of Ca2+ entry through mechanosensitive channels localizes the site of mechanoelectrical transduction in hair cells. Proc Natl Acad Sci U S A (1995) 1.86
The cellular basis of hearing: the biophysics of hair cells. Science (1985) 1.85
Response latency of vertebrate hair cells. Biophys J (1979) 1.84
RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels. Neuron (2002) 1.81
Mechanical stimulation and micromanipulation with piezoelectric bimorph elements. J Neurosci Methods (1980) 1.76
Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken's cochlea. Neuron (1997) 1.75
Mechanoelectrical transduction by hair cells in the acousticolateralis sensory system. Annu Rev Neurosci (1983) 1.73
The spatial pattern of cochlear amplification. Neuron (2012) 1.72
Directional sensitivity of individual vertebrate hair cells to controlled deflection of their hair bundles. Ann N Y Acad Sci (1981) 1.69
Identification of a 120 kd hair-bundle myosin located near stereociliary tips. Neuron (1993) 1.67
Displacement-clamp measurement of the forces exerted by gating springs in the hair bundle. Proc Natl Acad Sci U S A (1993) 1.67
Hair-bundle movements elicited by transepithelial electrical stimulation of hair cells in the sacculus of the bullfrog. Proc Natl Acad Sci U S A (2003) 1.63
Gating-spring models of mechanoelectrical transduction by hair cells of the internal ear. Annu Rev Biophys Biomol Struct (1995) 1.60
A two-step mechanism underlies the planar polarization of regenerating sensory hair cells. Proc Natl Acad Sci U S A (2006) 1.59
Hair cells: transduction, tuning, and transmission in the inner ear. Annu Rev Cell Biol (1988) 1.59
Effects of extracellular Ca2+ concentration on hair-bundle stiffness and gating-spring integrity in hair cells. Proc Natl Acad Sci U S A (1997) 1.59
Auditory illusions and the single hair cell. Nature (1993) 1.57
The selectivity of the hair cell's mechanoelectrical-transduction channel promotes Ca2+ flux at low Ca2+ concentrations. Proc Natl Acad Sci U S A (1997) 1.54
Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. J Neurosci (2008) 1.48
High-purity isolation of bullfrog hair bundles and subcellular and topological localization of constituent proteins. J Cell Biol (1991) 1.48
Retracted The remarkable cochlear amplifier. Hear Res (2010) 1.47
Parvalbumin 3 is an abundant Ca2+ buffer in hair cells. J Assoc Res Otolaryngol (2002) 1.47
Directional cell migration establishes the axes of planar polarity in the posterior lateral-line organ of the zebrafish. Dev Cell (2004) 1.45
Mechanical responses of the organ of corti to acoustic and electrical stimulation in vitro. Biophys J (2005) 1.32
Molecular markers for cell types of the inner ear and candidate genes for hearing disorders. Proc Natl Acad Sci U S A (1998) 1.30
A micromechanical contribution to cochlear tuning and tonotopic organization. Science (1983) 1.29
Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells. Proc Natl Acad Sci U S A (2004) 1.29
Specificity of afferent synapses onto plane-polarized hair cells in the posterior lateral line of the zebrafish. J Neurosci (2008) 1.28
Predominance of the alpha1D subunit in L-type voltage-gated Ca2+ channels of hair cells in the chicken's cochlea. Proc Natl Acad Sci U S A (1997) 1.28
Analysis and functional evaluation of the hair-cell transcriptome. Proc Natl Acad Sci U S A (2007) 1.27
Hair-bundle stiffness dominates the elastic reactance to otolithic-membrane shear. Hear Res (1993) 1.27
Establishment of tight junctions between epithelial cells. Proc Natl Acad Sci U S A (1975) 1.25
Vitamin A deprivation and Drosophila photopigments. Nature (1977) 1.25
Coexistence of gap and sseptate junctions in an invertebrate epithelium. J Cell Biol (1971) 1.24
Direct interaction with a nuclear protein and regulation of gene silencing by a variant of the Ca2+-channel beta 4 subunit. Proc Natl Acad Sci U S A (2002) 1.24
Expression and phylogeny of claudins in vertebrate primordia. Proc Natl Acad Sci U S A (2001) 1.21
Calmodulin and calmodulin-binding proteins in hair bundles. Proc Natl Acad Sci U S A (1993) 1.21
A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping. Genomics (2000) 1.19
A nonsense mutation in the gene encoding a zebrafish myosin VI isoform causes defects in hair-cell mechanotransduction. Proc Natl Acad Sci U S A (2004) 1.17
Passive signal propagation and membrane properties in median photoreceptors of the giant barnacle. J Physiol (1977) 1.15
The ionic channels of a vertebrate hair cell. Hear Res (1986) 1.15
Myosin-I nomenclature. J Cell Biol (2001) 1.14
Adenine nucleoside diphosphates block adaptation of mechanoelectrical transduction in hair cells. Proc Natl Acad Sci U S A (1993) 1.14
Controlled bending of high-resistance glass microelectrodes. Am J Physiol (1978) 1.13
Radixin is a constituent of stereocilia in hair cells. Proc Natl Acad Sci U S A (2004) 1.13
Supernumerary neuromasts in the posterior lateral line of zebrafish lacking peripheral glia. Proc Natl Acad Sci U S A (2005) 1.12
The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish. Proc Natl Acad Sci U S A (2009) 1.09
The entry and clearance of Ca2+ at individual presynaptic active zones of hair cells from the bullfrog's sacculus. Proc Natl Acad Sci U S A (1996) 1.09
Molecular anatomy of the hair cell's ribbon synapse. J Neurosci (2010) 1.08
Morphology and responses to light of the somata, axons, and terminal regions of individual photoreceptors of the giant barnacle. J Physiol (1977) 1.07
Forces between clustered stereocilia minimize friction in the ear on a subnanometre scale. Nature (2011) 1.06
Calmodulin controls adaptation of mechanoelectrical transduction by hair cells of the bullfrog's sacculus. Proc Natl Acad Sci U S A (1996) 1.04
Effects of salicylates and aminoglycosides on spontaneous otoacoustic emissions in the Tokay gecko. Proc Natl Acad Sci U S A (2000) 1.04
Hair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochlea. Proc Natl Acad Sci U S A (1997) 1.03
Vital staining of specific monoamine-containing cells in the leech nervous system. Cell Tissue Res (1974) 1.02
A ratchet mechanism for amplification in low-frequency mammalian hearing. Proc Natl Acad Sci U S A (2010) 1.01
Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous system. Mol Cell Neurosci (2003) 1.01
Two deaf mice, two deaf mice... Nat Med (1998) 0.99
Adaptive shift in the domain of negative stiffness during spontaneous oscillation by hair bundles from the internal ear. Proc Natl Acad Sci U S A (2005) 0.99
Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line. Proc Natl Acad Sci U S A (2014) 0.97
Modeling the active process of the cochlea: phase relations, amplification, and spontaneous oscillation. Biophys J (1995) 0.95
Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient. Mol Cell Biol (2010) 0.94
Association of beta-catenin with the alpha-subunit of neuronal large-conductance Ca2+-activated K+ channels. Proc Natl Acad Sci U S A (2003) 0.94