Published in Oncogene on January 11, 2010
Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anticancer agents. Mol Cancer Res (2011) 1.13
A mortalin/HSPA9-mediated switch in tumor-suppressive signaling of Raf/MEK/extracellular signal-regulated kinase. Mol Cell Biol (2013) 1.02
Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells. Aging Cell (2011) 0.99
The HSP90 inhibitor NVP-AUY922 radiosensitizes by abrogation of homologous recombination resulting in mitotic entry with unresolved DNA damage. PLoS One (2012) 0.98
Endoplasmic reticulum stress, genome damage, and cancer. Front Oncol (2015) 0.90
Phenotypic identification of the redox dye methylene blue as an antagonist of heat shock response gene expression in metastatic melanoma cells. Int J Mol Sci (2013) 0.81
Sp1-mediated transcriptional activation of miR-205 promotes radioresistance in esophageal squamous cell carcinoma. Oncotarget (2016) 0.80
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicol Appl Pharmacol (2011) 0.78
C/EBPδ deficiency sensitizes mice to ionizing radiation-induced hematopoietic and intestinal injury. PLoS One (2014) 0.78
Induction of Hsp70 in tumor cells treated with inhibitors of the Hsp90 activity: A predictive marker and promising target for radiosensitization. PLoS One (2017) 0.75
Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells. Cancer Res (2016) 0.75
The chaperone function of hsp70 is required for protection against stress-induced apoptosis. Mol Cell Biol (2000) 2.69
Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance. J Biol Chem (1997) 2.31
Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72. Mol Cell Biol (1999) 1.75
Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins in Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.69
Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis. J Biol Chem (1998) 1.67
Role of Hsp70 in regulation of stress-kinase JNK: implications in apoptosis and aging. FEBS Lett (1998) 1.57
Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis. Oncogene (2010) 1.45
Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death. Mol Cell Biol (2000) 1.42
Oncogenic potential of Hsp72. Oncogene (1999) 1.42
The molecular chaperone Ydj1 is required for the p34CDC28-dependent phosphorylation of the cyclin Cln3 that signals its degradation. Mol Cell Biol (1996) 1.30
Role of molecular chaperones in neurodegenerative disorders. Int J Hyperthermia (2005) 1.16
Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis. Oncogene (2011) 1.06
The function of HSP72 in suppression of c-Jun N-terminal kinase activation can be dissociated from its role in prevention of protein damage. J Biol Chem (1999) 1.05
Suppression of stress kinase JNK is involved in HSP72-mediated protection of myogenic cells from transient energy deprivation. HSP72 alleviates the stewss-induced inhibition of JNK dephosphorylation. J Biol Chem (2000) 1.02
The molecular chaperone DnaJ is required for the degradation of a soluble abnormal protein in Escherichia coli. J Biol Chem (2000) 1.01
Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1. J Cell Biol (2001) 1.00
Reduced thermotolerance in aged cells results from a loss of an hsp72-mediated control of JNK signaling pathway. Cell Stress Chaperones (1998) 0.97
ATPase activity of the heat shock protein hsp72 is dispensable for its effects on dephosphorylation of stress kinase JNK and on heat-induced apoptosis. FEBS Lett (1999) 0.93
HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK. Cell Stress Chaperones (2000) 0.92
Adjuvant potential of aggregate-forming polyglutamine domains. Vaccine (2008) 0.92
Development of an XTT tetrazolium salt-based assay for detection of specific hyperthermia sensitizers in a high-flux screening programme. Int J Hyperthermia (2002) 0.81
Interrelation between taxis and sporulation systems. FEBS Lett (1982) 0.75