Published in PLoS Genet on January 08, 2010
Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration. J Clin Invest (2013) 1.83
Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a. PLoS One (2010) 1.49
Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission. J Cell Biol (2017) 1.47
Epigenetics, epidemiology and mitochondrial DNA diseases. Int J Epidemiol (2012) 1.36
Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta (2013) 1.29
MicroRNAs in apoptosis, autophagy and necroptosis. Oncotarget (2015) 1.17
Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury. Front Physiol (2011) 1.14
Downregulation of microRNA-30 facilitates podocyte injury and is prevented by glucocorticoids. J Am Soc Nephrol (2013) 1.12
Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage. Blood (2011) 1.12
A combined array-based comparative genomic hybridization and functional library screening approach identifies mir-30d as an oncomir in cancer. Cancer Res (2011) 1.10
Transforming growth factor-β, bioenergetics, and mitochondria in renal disease. Semin Nephrol (2012) 1.09
mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells. Biochem Biophys Res Commun (2012) 1.08
Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species. Free Radic Biol Med (2011) 1.06
Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death. J Neurosci (2013) 0.99
Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution. PLoS One (2012) 0.99
p53 and mitochondrial function in neurons. Biochim Biophys Acta (2014) 0.97
MicroRNAs in pancreatic cancer metabolism. Nat Rev Gastroenterol Hepatol (2012) 0.97
Compromised autophagy by MIR30B benefits the intracellular survival of Helicobacter pylori. Autophagy (2012) 0.96
miR-30b, down-regulated in gastric cancer, promotes apoptosis and suppresses tumor growth by targeting plasminogen activator inhibitor-1. PLoS One (2014) 0.95
Micro-RNA30c negatively regulates REDD1 expression in human hematopoietic and osteoblast cells after gamma-irradiation. PLoS One (2012) 0.95
MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3. PLoS One (2013) 0.94
The miR-30 microRNA family targets smoothened to regulate hedgehog signalling in zebrafish early muscle development. PLoS One (2013) 0.93
The targeting and functions of miRNA-383 are mediated by FMRP during spermatogenesis. Cell Death Dis (2013) 0.93
Control of mitochondrial activity by miRNAs. J Cell Biochem (2012) 0.92
Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes. PLoS One (2013) 0.90
Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model. PLoS One (2012) 0.90
miR-19b promotes tumor growth and metastasis via targeting TP53. RNA (2014) 0.90
Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo. Biochem J (2014) 0.89
The altered expression profile of microRNAs in cardiopulmonary bypass canine models and the effects of mir-499 on myocardial ischemic reperfusion injury. J Transl Med (2013) 0.89
MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells. PLoS One (2012) 0.89
hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3. Cancer Cell Int (2014) 0.89
New insights into mechanisms of cardioprotection mediated by thyroid hormones. J Thyroid Res (2013) 0.88
Small molecules, big effects: the role of microRNAs in regulation of cardiomyocyte death. Cell Death Dis (2014) 0.88
Estrogen regulates the tumour suppressor MiRNA-30c and its target gene, MTA-1, in endometrial cancer. PLoS One (2014) 0.88
Mitochondrial morphology-emerging role in bioenergetics. Free Radic Biol Med (2012) 0.87
New insights into p53 functions through its target microRNAs. J Mol Cell Biol (2014) 0.87
p53 as guardian of the mitochondrial genome. FEBS Lett (2016) 0.87
Metabolic regulation of oxygen and redox homeostasis by p53: lessons from evolutionary biology? Free Radic Biol Med (2012) 0.86
Mitochondria as key targets of cardioprotection in cardiac ischemic disease: role of thyroid hormone triiodothyronine. Int J Mol Sci (2015) 0.86
Mitofusin 1 is negatively regulated by microRNA 140 in cardiomyocyte apoptosis. Mol Cell Biol (2014) 0.86
Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis. Biochim Biophys Acta (2015) 0.86
MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes. J Clin Invest (2015) 0.86
Mitochondrial network in the heart. Protein Cell (2012) 0.85
Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN. Sci Rep (2015) 0.85
Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia. BMC Genomics (2014) 0.85
MicroRNA and MET in lung cancer. Ann Transl Med (2015) 0.84
miR-361-regulated prohibitin inhibits mitochondrial fission and apoptosis and protects heart from ischemia injury. Cell Death Differ (2014) 0.84
MiRNA-30a inhibits AECs-II apoptosis by blocking mitochondrial fission dependent on Drp-1. J Cell Mol Med (2014) 0.84
Modulated expression of human peripheral blood microRNAs from infancy to adulthood and its role in aging. Aging Cell (2014) 0.83
Genetic networks lead and follow tumor development: microRNA regulation of cell cycle and apoptosis in the p53 pathways. Biomed Res Int (2014) 0.82
miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor. Exp Mol Med (2014) 0.82
The use of microRNAs to modulate redox and immune response to stroke. Antioxid Redox Signal (2015) 0.81
Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Sci Rep (2016) 0.81
Stage-Wise Identification and Analysis of miRNA from Root-Knot Nematode Meloidogyne incognita. Int J Mol Sci (2016) 0.81
High dose ionizing radiation regulates micro RNA and gene expression changes in human peripheral blood mononuclear cells. BMC Genomics (2014) 0.81
miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One (2015) 0.81
Effect of high sugar levels on miRNA expression. Studies with galactosemic mice lenses. Mol Vis (2012) 0.81
Overview of MicroRNAs in Cardiac Hypertrophy, Fibrosis, and Apoptosis. Int J Mol Sci (2016) 0.80
Cardiomyocyte-specific miRNA-30c over-expression causes dilated cardiomyopathy. PLoS One (2014) 0.80
The Role of microRNAs in Mitochondria: Small Players Acting Wide. Genes (Basel) (2014) 0.80
microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis. Oncotarget (2016) 0.79
MicroRNAs in Kidney Transplantation: Living up to Their Expectations? J Transplant (2015) 0.79
MiR-106b-mediated Mfn2 suppression is critical for PKM2 induced mitochondrial fusion. Am J Cancer Res (2016) 0.79
E2F1-regulated miR-30b suppresses Cyclophilin D and protects heart from ischemia/reperfusion injury and necrotic cell death. Cell Death Differ (2014) 0.79
Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects. Br J Pharmacol (2014) 0.79
MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting Mitofusin-2. Cancer Sci (2016) 0.78
Effect of p53 on mitochondrial morphology, import, and assembly in skeletal muscle. Am J Physiol Cell Physiol (2014) 0.78
Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission. J Cell Mol Med (2015) 0.78
miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3. Oncotarget (2016) 0.77
A critical evaluation of neuroprotective and neurodegenerative MicroRNAs in Alzheimer's disease. Biochem Biophys Res Commun (2016) 0.77
A Systematic Analysis on mRNA and MicroRNA Expression in Runting and Stunting Chickens. PLoS One (2015) 0.77
Mitochondrial Activity in Human White Adipocytes Is Regulated by the Ubiquitin Carrier Protein 9/microRNA-30a Axis. J Biol Chem (2016) 0.77
Mesenchymal Stromal Cells Derived Extracellular Vesicles Ameliorate Acute Renal Ischemia Reperfusion Injury by Inhibition of Mitochondrial Fission through miR-30. Stem Cells Int (2016) 0.76
Mitochondrial death functions of p53. Mol Cell Oncol (2014) 0.76
Looking into a conceptual framework of ROS-miRNA-atrial fibrillation. Int J Mol Sci (2014) 0.76
miRNAs in Sera of Tunisian patients discriminate between inflammatory breast cancer and non-inflammatory breast cancer. Springerplus (2014) 0.76
Unveiling the principle of microRNA-mediated redundancy in cellular pathway regulation. RNA Biol (2015) 0.76
Mitochondrial fission and fusion in secondary brain damage after CNS insults. J Cereb Blood Flow Metab (2016) 0.76
Sprint-interval but not continuous exercise increases PGC-1α protein content and p53 phosphorylation in nuclear fractions of human skeletal muscle. Sci Rep (2017) 0.75
Morphological control of mitochondrial bioenergetics. Front Biosci (Landmark Ed) (2015) 0.75
miR-30b inhibits autophagy to alleviate hepatic ischemia-reperfusion injury via decreasing the Atg12-Atg5 conjugate. World J Gastroenterol (2016) 0.75
Non-coding RNAs: the dark side of nuclear-mitochondrial communication. EMBO J (2017) 0.75
miR-30a as Potential Therapeutics by Targeting TET1 through Regulation of Drp-1 Promoter Hydroxymethylation in Idiopathic Pulmonary Fibrosis. Int J Mol Sci (2017) 0.75
Novel Insights into Insect-Microbe Interactions-Role of Epigenomics and Small RNAs. Front Plant Sci (2016) 0.75
Identification of common tumor signatures based on gene set enrichment analysis. In Silico Biol (2012) 0.75
The Role and Molecular Mechanism of Non-Coding RNAs in Pathological Cardiac Remodeling. Int J Mol Sci (2017) 0.75
Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice. Exp Gerontol (2017) 0.75
Metadherin facilitates podocyte apoptosis in diabetic nephropathy. Cell Death Dis (2016) 0.75
MicroRNA and hyperglycemic memory in the diabetic heart. J Thorac Dis (2016) 0.75
Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse. Sci Rep (2016) 0.75
Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability. Oncotarget (2016) 0.75
Heterogeneous nuclear ribonucleoprotein A1 post-transcriptionally regulates Drp1 expression in neuroblastoma cells. Biochim Biophys Acta (2015) 0.75
microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases. Front Med (Lausanne) (2017) 0.75
Mitochondrial protein 18 (MTP18) plays a pro-apoptotic role in chemotherapy-induced gastric cancer cell apoptosis. Oncotarget (2017) 0.75
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MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene (2007) 10.79
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Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
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Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function. Clin Immunol (2009) 1.11
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MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells. J Biol Chem (2007) 1.05
Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4. J Biol Chem (2010) 1.04
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Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene. Cancer Res (2008) 0.97
Targeted engagement of CTLA-4 prevents autoimmune thyroiditis. Int Immunol (2003) 0.97
The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis. J Immunol (2013) 0.95
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Human monoclonal antibodies against highly conserved HR1 and HR2 domains of the SARS-CoV spike protein are more broadly neutralizing. PLoS One (2012) 0.93
The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. J Gen Virol (2009) 0.92
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Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease. J Med Chem (2009) 0.92
IG20, a MADD splice variant, increases cell susceptibility to gamma-irradiation and induces soluble mediators that suppress tumor cell growth. Cancer Res (2003) 0.92
Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors. Bioorg Med Chem Lett (2008) 0.92
Correlation between chemosensitivity to anticancer drugs and Bcl-2 expression in gastric cancer. Int J Clin Exp Pathol (2013) 0.91
TNF-α, erectile dysfunction, and NADPH oxidase-mediated ROS generation in corpus cavernosum in high-fat diet/streptozotocin-induced diabetic rats. J Sex Med (2012) 0.91
Nanodisc-incorporated hemagglutinin provides protective immunity against influenza virus infection. J Virol (2010) 0.91
Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity. J Interferon Cytokine Res (2011) 0.91
TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure. Hepatology (2012) 0.91
Prevalence of antibody to hepatitis E virus among pet dogs in the Jiang-Zhe area of China. Scand J Infect Dis (2009) 0.90
OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells. J Immunol (2013) 0.90
The gamma 1 34.5 protein of herpes simplex virus 1 is required to interfere with dendritic cell maturation during productive infection. J Virol (2009) 0.90
GM-CSF-induced regulatory T cells selectively inhibit anti-acetylcholine receptor-specific immune responses in experimental myasthenia gravis. J Neuroimmunol (2011) 0.90
Identification of human cell responses to benzene and benzene metabolites. Genomics (2007) 0.89
miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor. Free Radic Biol Med (2013) 0.89
Functional, morphological, and apoptotic alterations in skeletal muscle of ARC deficient mice. Apoptosis (2015) 0.89
Absence of IL-4, and not suppression of the Th2 response, prevents development of experimental autoimmune Graves' disease. J Immunol (2003) 0.89
Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells. Am J Obstet Gynecol (2011) 0.89
Ovarian mucinous cystic tumor with sarcoma-like mural nodules and multifocal anaplastic carcinoma: a case report. Int J Clin Exp Pathol (2013) 0.89
Human monoclonal antibodies to SARS-coronavirus inhibit infection by different mechanisms. Virology (2009) 0.88
Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes. J Immunol (2010) 0.88
Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis. J Clin Endocrinol Metab (2009) 0.88
Identification of human cell responses to hexavalent chromium. Environ Mol Mutagen (2007) 0.87
MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells. PLoS One (2013) 0.86
Mitofusin 1 is negatively regulated by microRNA 140 in cardiomyocyte apoptosis. Mol Cell Biol (2014) 0.86
Mitochondrial fission controls DNA fragmentation by regulating endonuclease G. Free Radic Biol Med (2010) 0.86
CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties. Int Immunol (2003) 0.86
Generation and characterization of human monoclonal neutralizing antibodies with distinct binding and sequence features against SARS coronavirus using XenoMouse. Virology (2006) 0.85
Functional defect in regulatory T cells in myasthenia gravis. Ann N Y Acad Sci (2012) 0.84
Highly efficient piezotronic strain sensors with symmetrical Schottky contacts on the monopolar surface of ZnO nanobelts. Nanoscale (2015) 0.84
DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency. Eur J Immunol (2014) 0.84
IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells. PLoS One (2011) 0.84
Strategies for treating autoimmunity: novel insights from experimental myasthenia gravis. Ann N Y Acad Sci (2008) 0.84
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Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential. Rev Med Virol (2011) 0.83
Cytotoxic polyketide derivatives from the South China Sea sponge Plakortis simplex. J Nat Prod (2013) 0.82
Transcription factor Foxo3a prevents apoptosis by regulating calcium through the apoptosis repressor with caspase recruitment domain. J Biol Chem (2013) 0.82
Transfusion of nonobese diabetic mice with allogeneic newborn blood ameliorates autoimmune diabetes and modifies the expression of selected immune response genes. J Immunol (2010) 0.81
Mitochondrial fission leads to Smac/DIABLO release quenched by ARC. Apoptosis (2010) 0.81
Modulation of dendritic cell function and cytokine production to prevent thyroid autoimmunity. Autoimmunity (2003) 0.81
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Acetylcholine receptor-alpha subunit expression in myasthenia gravis: a role for the autoantigen in pathogenesis? Muscle Nerve (2009) 0.80
The p53-induced Siva-1 plays a significant role in cisplatin-mediated apoptosis. J Carcinog (2009) 0.80
Activation of NF-κB in CD8+ dendritic cells Ex Vivo by the γ134.5 null mutant correlates with immunity against herpes simplex virus 1. J Virol (2011) 0.80
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Characterization of a recombinant Yersinia enterocolitica lipoprotein; implications for its role in autoimmune response against thyrotropin receptor. Autoimmunity (2004) 0.79
Developmental expression pattern of a novel gene, TSG23/Tsg23, suggests a role in spermatogenesis. Mol Hum Reprod (2009) 0.78
IG20/MADD plays a critical role in glucose-induced insulin secretion. Diabetes (2013) 0.78
Multicystic meningioangiomatosis. BMC Neurol (2014) 0.78
Expression of the ring ligase PRAJA2 in thyroid cancer. J Clin Endocrinol Metab (2012) 0.78
A unique composite follicular lymphoma and mantle cell lymphoma with a mixed cell pattern and aggressive course. Am J Clin Pathol (2014) 0.78
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Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model. Biochem Biophys Res Commun (2010) 0.77
Diversity in the complementarity-determining region 3 (CDR3) of antibodies from mice with evolving anti-thyroid-stimulating hormone receptor antibody responses. Endocrinology (2006) 0.77
Upon thyrotropin binding the thyrotropin receptor is internalized and localized to endosome. Endocrinology (2003) 0.77
Taurochenodeoxycholic acid induces apoptosis of fibroblast-like synoviocytes. Eur J Pharmacol (2013) 0.76
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