Published in Mol Vis on January 13, 2010
Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders. Pharmacol Ther (2010) 1.39
Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells. Cell Res (2011) 1.13
Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis. PLoS One (2012) 0.98
Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism. Mol Immunol (2012) 0.86
EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell-mediated immunotherapy. Mol Vis (2012) 0.85
AP2 transcription factor induces apoptosis in retinoblastoma cells. Genes Chromosomes Cancer (2010) 0.85
GSK3 inhibitor-BIO regulates proliferation of immortalized pancreatic mesenchymal stem cells (iPMSCs). PLoS One (2012) 0.84
Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol (2011) 0.83
Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation. BMC Cancer (2012) 0.82
Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling. FASEB J (2015) 0.79
Reduced photoreceptor death and improved retinal function during retinal degeneration in mice lacking innate immunity adaptor protein MyD88. Exp Neurol (2015) 0.78
Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation. PLoS One (2015) 0.77
Lithium chloride has a biphasic effect on prostate cancer stem cells and a proportional effect on midkine levels. Oncol Lett (2016) 0.76
Role of Wnt signaling on proliferation of menstrual blood derived stem cells. J Stem Cells Regen Med (2013) 0.75
Acceleration of bone regeneration by activating Wnt/β-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis. Sci Rep (2017) 0.75
Lithium chloride promotes neuronal differentiation of rat neural stem cells and enhances neural regeneration in Parkinson's disease model. Cytotechnology (2017) 0.75
Regulated differentiation of WERI-Rb-1 cells into retinal neuron-like cells. Int J Mol Med (2017) 0.75
Hypoxia stimulates neural stem cell proliferation by increasing HIF‑1α expression and activating Wnt/β-catenin signaling. Cell Mol Biol (Noisy-le-grand) (2017) 0.75
Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17
Stem cells, cancer, and cancer stem cells. Nature (2001) 50.27
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature (2006) 27.91
Wnt signalling in stem cells and cancer. Nature (2005) 19.26
Tumour stem cells and drug resistance. Nat Rev Cancer (2005) 15.21
Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res (2005) 13.89
Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature (2003) 12.54
Socializing with the neighbors: stem cells and their niche. Cell (2004) 9.40
Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol (1998) 9.24
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell (2003) 7.93
A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res (2005) 7.86
Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta (2003) 7.85
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. Science (2000) 7.25
Tumor heterogeneity. Cancer Res (1984) 6.17
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol (2001) 6.12
Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature (2008) 5.59
Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol (2007) 4.75
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60
Retinal stem cells in the adult mammalian eye. Science (2000) 3.97
Biological diversity in metastatic neoplasms: origins and implications. Science (1982) 3.95
Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis. J Clin Oncol (2008) 3.84
Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human. Dev Dyn (2004) 3.13
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat Med (2005) 2.60
Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors. Science (1985) 2.49
The incidence of retinoblastoma in the United States: 1974 through 1985. Arch Ophthalmol (1990) 2.43
Wnt signaling promotes regeneration in the retina of adult mammals. J Neurosci (2007) 2.29
Identification of neural progenitors in the adult mammalian eye. Biochem Biophys Res Commun (2000) 1.95
Neural stem cell properties of Müller glia in the mammalian retina: regulation by Notch and Wnt signaling. Dev Biol (2006) 1.92
Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina. Neuron (2005) 1.80
Cancer stem cell characteristics in retinoblastoma. Mol Vis (2005) 1.77
Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus. Int J Cancer (2005) 1.75
The search for the retinoblastoma cell of origin. Nat Rev Cancer (2005) 1.72
Human embryonic and neuronal stem cell markers in retinoblastoma. Mol Vis (2007) 1.66
Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth. Oncogene (2004) 1.54
Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development (2003) 1.46
Lithium neuroprotection: molecular mechanisms and clinical implications. Expert Rev Mol Med (2004) 1.44
Metastatic and nonmetastatic models of retinoblastoma. Am J Pathol (2000) 1.41
Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development (2006) 1.40
Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med (2006) 1.40
Wnt signalling and the mechanistic basis of tumour development. J Pathol (2005) 1.36
Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Invest Ophthalmol Vis Sci (2004) 1.33
Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling. Dev Biol (2007) 1.22
Wnt signaling in eye organogenesis. Organogenesis (2008) 1.21
Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. Int J Cancer (2005) 1.20
Stem cell-like cancer cells in cancer cell lines. Cancer Biomark (2007) 1.11
SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a. Stem Cells (2007) 1.09
Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin. Stem Cells (2005) 1.03
Retinal stem cells in vertebrates: parallels and divergences. Int J Dev Biol (2004) 1.02
Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes. Stem Cells (2008) 0.95
The canonical Wnt pathway regulates retinal stem cells/progenitors in concert with Notch signaling. Dev Neurosci (2008) 0.90
The Wnt signaling pathway has tumor suppressor properties in retinoblastoma. Biochem Biophys Res Commun (2006) 0.89
Phenotypic characterization of retinoblastoma for the presence of putative cancer stem-like cell markers by flow cytometry. Invest Ophthalmol Vis Sci (2008) 0.89
Investigation of mRNA expression for secreted frizzled-related protein 2 (sFRP2) in chick embryos. J Reprod Dev (2007) 0.81
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol (2002) 2.50
Human embryonic and neuronal stem cell markers in retinoblastoma. Mol Vis (2007) 1.66
Evaluation of in vitro effects of bevacizumab (Avastin) on retinal pigment epithelial, neurosensory retinal, and microvascular endothelial cells. Retina (2006) 1.25
Multiple RIBEYE-RIBEYE interactions create a dynamic scaffold for the formation of synaptic ribbons. J Neurosci (2008) 1.22
Toxicity of triamcinolone acetonide on retinal neurosensory and pigment epithelial cells. Invest Ophthalmol Vis Sci (2006) 1.16
Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina. BMC Cell Biol (2007) 1.13
The gap-startle paradigm for tinnitus screening in animal models: limitations and optimization. Hear Res (2012) 1.13
Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression. Int J Mol Med (2004) 1.13
Evidence of apoptotic cell death in keratoconus. Cornea (2002) 1.12
Gene expression variation in the adult human retina. Hum Mol Genet (2003) 1.12
Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray. Invest Ophthalmol Vis Sci (2003) 1.11
Evolutionarily conserved ELOVL4 gene expression in the vertebrate retina. Invest Ophthalmol Vis Sci (2003) 1.11
Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. Biochem Pharmacol (2011) 1.10
Trypan blue: effect on retinal pigment epithelial and neurosensory retinal cells. Invest Ophthalmol Vis Sci (2005) 1.07
Increased expression of iron-regulating genes in monkey and human glaucoma. Invest Ophthalmol Vis Sci (2004) 1.07
Analysis of Dickkopf3 interactions with Wnt signaling receptors. Growth Factors (2010) 1.05
RIBEYE recruits Munc119, a mammalian ortholog of the Caenorhabditis elegans protein unc119, to synaptic ribbons of photoreceptor synapses. J Biol Chem (2008) 1.04
Immunoreactivity of ICAM-1 in human tumors, metastases and normal tissues. Int J Clin Exp Pathol (2009) 0.98
Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis. PLoS One (2012) 0.98
Retinal precursor cells express functional ionotropic glutamate and GABA receptors. Neuroreport (2002) 0.97
Characterization of Wnt signaling during photoreceptor degeneration. Invest Ophthalmol Vis Sci (2007) 0.97
Autofluorescence and infrared retinal imaging in patients and obligate carriers with neuronal ceroid lipofuscinosis. Ophthalmic Genet (2009) 0.96
Oxysterol-induced toxicity in R28 and ARPE-19 cells. Neurochem Res (2003) 0.93
Cisplatin-induced ototoxicity is mediated by nitroxidative modification of cochlear proteins characterized by nitration of Lmo4. J Biol Chem (2012) 0.92
Latanoprost rescues retinal neuro-glial cells from apoptosis by inhibiting caspase-3, which is mediated by p44/p42 mitogen-activated protein kinase. Exp Eye Res (2006) 0.91
The Wnt signaling pathway protects retinal ganglion cell 5 (RGC-5) cells from elevated pressure. Cell Mol Neurobiol (2011) 0.91
Cisplatin ototoxicity in rat cochlear organotypic cultures. Hear Res (2011) 0.90
Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Invest Ophthalmol Vis Sci (2004) 0.89
The Wnt signaling pathway has tumor suppressor properties in retinoblastoma. Biochem Biophys Res Commun (2006) 0.89
The Wnt/β-catenin pathway cross-talks with STAT3 signaling to regulate survival of retinal pigment epithelium cells. PLoS One (2012) 0.88
An investigation of the neuroprotective effects of tetracycline derivatives in experimental models of retinal cell death. Mol Pharmacol (2004) 0.86
Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism. Mol Immunol (2012) 0.86
A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina. Vision Res (2010) 0.86
Expression of brain-derived neurotrophic factor is regulated by the Wnt signaling pathway. Neuroreport (2012) 0.84
A novel behavioral assay for the assessment of acute tinnitus in rats optimized for simultaneous recording of oscillatory neural activity. J Neurosci Methods (2013) 0.83
cAMP-responsive element binding protein mediates a cGMP/protein kinase G-dependent anti-apoptotic signal induced by nitric oxide in retinal neuro-glial progenitor cells. Exp Eye Res (2006) 0.83
Differential effects of nicotine on retinal and vascular cells in vitro. Toxicology (2009) 0.82
Toxicity of indocyanine green (ICG) in combination with light on retinal pigment epithelial cells and neurosensory retinal cells. Curr Eye Res (2005) 0.80
Chromatin structure and expression of synapsin I and synaptophysin in retinal precursor cells. Neurochem Int (2008) 0.80
The effects of commercially available preservative-free FDA-approved triamcinolone (Triesence®) on retinal cells in culture. J Ocul Pharmacol Ther (2011) 0.80
Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells. Biomark Insights (2008) 0.79
Gene Transfer of Glutamic Acid Decarboxylase 67 by Herpes Simplex Virus Vectors Suppresses Neuropathic Pain Induced by Human Immunodeficiency Virus gp120 Combined with ddC in Rats. Anesth Analg (2015) 0.79
Effects of benzo(e)pyrene on the retinal neurosensory cells and human microvascular endothelial cells in vitro. Curr Eye Res (2009) 0.79
Inhibition of Mitochondrial Fission Protein Reduced Mechanical Allodynia and Suppressed Spinal Mitochondrial Superoxide Induced by Perineural Human Immunodeficiency Virus gp120 in Rats. Anesth Analg (2016) 0.79
Translation of genetic discoveries into clinical therapies. Ann Intern Med (2008) 0.78
HIV-1 Tat-mediated neurotoxicity in retinal cells. J Neuroimmune Pharmacol (2011) 0.78
Effects of hydroquinone on retinal and vascular cells in vitro. Indian J Ophthalmol (2012) 0.77
Mechanical allodynia induced by nucleoside reverse transcriptase inhibitor is suppressed by p55TNFSR mediated by herpes simplex virus vector through the SDF1α/CXCR4 system in rats. Anesth Analg (2014) 0.77
RB116: an RB1+ retinoblastoma cell line expressing primitive markers. Mol Vis (2012) 0.77
Basic fibroblast growth factor impact on retinoblastoma progression and survival. Invest Ophthalmol Vis Sci (2008) 0.76
Effect of bevacizumab (Avastin (TM) ) on mitochondrial function of in vitro retinal pigment epithelial, neurosensory retinal and microvascular endothelial cells. Indian J Ophthalmol (2013) 0.75
Application of Scanning Electron Microscopy With Energy-Dispersive X-Ray Spectroscopy for Analyzing Ocular Surface Particles on Schirmer Strips. Cornea (2017) 0.75