Genomic scale analysis of racial impact on response to IFN-alpha.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMC 2818915)

Published in Proc Natl Acad Sci U S A on December 22, 2009

Authors

Zoltan Pos1, Silvia Selleri, Tara L Spivey, Jeanne K Wang, Hui Liu, Andrea Worschech, Marianna Sabatino, Alessandro Monaco, Susan F Leitman, Andras Falus, Ena Wang, Harvey J Alter, Francesco M Marincola

Author Affiliations

1: Infectious Disease and Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, and Center for Human Immunology, National Institutes of Health, Bethesda, MD 20892, USA. posz@cc.nih.gov

Articles citing this

The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women. AIDS (2011) 1.94

Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis. J Transl Med (2011) 1.15

Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age- and race-associated differences in immune signaling pathway activation. J Immunol (2012) 1.10

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2. Br J Cancer (2013) 1.06

Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes. J Immunol (2011) 1.00

Widely divergent transcriptional patterns between SLE patients of different ancestral backgrounds in sorted immune cell populations. J Autoimmun (2015) 0.86

Racial differences in B cell receptor signaling pathway activation. J Transl Med (2012) 0.84

Therapeutic cancer vaccines and translating vaccinomics science to the global health clinic: emerging applications toward proof of concept. OMICS (2011) 0.83

Melanoma NOS1 expression promotes dysfunctional IFN signaling. J Clin Invest (2014) 0.81

Inter-donor variation in cell subset specific immune signaling responses in healthy individuals. Am J Clin Exp Immunol (2012) 0.76

Advances in hepatology: current developments in the treatment of hepatitis and hepatobiliary disease. Gastroenterol Hepatol (N Y) (2010) 0.75

Articles cited by this

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature (2009) 26.47

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet (2009) 14.16

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature (2009) 13.99

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet (2009) 13.03

Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol (2005) 11.57

The genetic structure and history of Africans and African Americans. Science (2009) 10.65

Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol (2005) 9.00

Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites. N Engl J Med (2004) 8.12

The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. J Leukoc Biol (2004) 2.81

Viral dynamics and response differences in HCV-infected African American and white patients treated with IFN and ribavirin. Hepatology (2003) 2.50

Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (2006) 2.03

Impaired interferon signaling is a common immune defect in human cancer. Proc Natl Acad Sci U S A (2009) 1.66

Racial differences in responses to therapy with interferon in chronic hepatitis C. Consensus Interferon Study Group. Hepatology (1999) 1.59

RNA amplification for successful gene profiling analysis. J Transl Med (2005) 1.55

Differences in treatment outcome for hepatitis C among ethnic groups. Am J Med (2004) 1.48

Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon Alfa immunotherapy. J Natl Cancer Inst (2004) 1.42

ISG15, a ubiquitin-like interferon-stimulated gene, promotes hepatitis C virus production in vitro: implications for chronic infection and response to treatment. J Gen Virol (2009) 1.40

Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the response to interferon therapy for chronic hepatitis C. J Hepatol (2008) 1.17

Mechanisms of HCV survival in the host. Nat Rev Gastroenterol Hepatol (2009) 1.07

Intrahepatic MxA and PKR protein expression in chronic hepatitis C virus infection. J Med Virol (2002) 0.97

Articles by these authors

Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 24.41

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol (2008) 10.13

The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19

A human memory T cell subset with stem cell-like properties. Nat Med (2011) 7.47

Peripheral-blood stem cells versus bone marrow from unrelated donors. N Engl J Med (2012) 6.30

Chromatin structure analyses identify miRNA promoters. Genes Dev (2008) 5.40

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med (2007) 5.18

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med (2011) 5.15

Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science (2013) 5.09

Retracted Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors. Proc Natl Acad Sci U S A (2010) 4.31

A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma. J Immunother (2002) 4.31

Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma. J Clin Oncol (2002) 4.15

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet (2008) 3.76

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. Nat Immunol (2005) 3.23

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours. J Pathol (2014) 3.21

Heterosexual transmission of HIV in China: a systematic review of behavioral studies in the past two decades. Sex Transm Dis (2005) 3.10

Unlocking the barley genome by chromosomal and comparative genomics. Plant Cell (2011) 3.03

Serum vascular endothelial growth factor and fibronectin predict clinical response to high-dose interleukin-2 therapy. J Clin Oncol (2009) 3.02

Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics. Dev Cell (2004) 2.96

Tumour immunity: effector response to tumour and role of the microenvironment. Lancet (2008) 2.94

Cancer classification using the Immunoscore: a worldwide task force. J Transl Med (2012) 2.88

The continuum of cancer immunosurveillance: prognostic, predictive, and mechanistic signatures. Immunity (2013) 2.86

You make me sick: marital quality and health over the life course. J Health Soc Behav (2006) 2.81

The immune score as a new possible approach for the classification of cancer. J Transl Med (2012) 2.79

The dragon strikes: lessons from the Wenchuan earthquake. Anesth Analg (2010) 2.78

Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nat Genet (2004) 2.77

Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus. Cancer Res (2007) 2.69

Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science (2009) 2.68

Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease. Arterioscler Thromb Vasc Biol (2004) 2.65

Emerging HIV-1 epidemic in China in men who have sex with men. Lancet (2003) 2.62

Comparison of unilateral versus bilateral pedicle screw fixation in lumbar interbody fusion: a meta-analysis. Eur Spine J (2013) 2.57

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J Exp Med (2010) 2.57

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles. J Am Chem Soc (2004) 2.54

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci U S A (2012) 2.51

MicroRNA expression differentiates histology and predicts survival of lung cancer. Clin Cancer Res (2010) 2.48

Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology (2003) 2.45

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol Cell Proteomics (2011) 2.43

SLAF-seq: an efficient method of large-scale de novo SNP discovery and genotyping using high-throughput sequencing. PLoS One (2013) 2.36

BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Nature (2013) 2.36

Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32

Defining the critical hurdles in cancer immunotherapy. J Transl Med (2011) 2.32

Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells. Nat Med (2010) 2.30

Interleukin-10 and the immune response against cancer: a counterpoint. J Leukoc Biol (2005) 2.24

Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness. Cancer Res (2002) 2.21

Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: a longitudinal analysis. Hepatology (2013) 2.17

Genome-wide SNP discovery and linkage analysis in barley based on genes responsive to abiotic stress. Mol Genet Genomics (2005) 2.16

Matrix metalloproteinase 2 expression and survival of patients with osteosarcoma: a meta-analysis. Tumour Biol (2013) 2.16

AnimalTFDB: a comprehensive animal transcription factor database. Nucleic Acids Res (2011) 2.15

Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines. Clin Cancer Res (2002) 2.14

Extensive HLA class I allele promiscuity among viral CTL epitopes. Eur J Immunol (2007) 2.10

Vesicle trafficking plays a novel role in erythroblast enucleation. Blood (2010) 2.07

Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome. Proc Natl Acad Sci U S A (2002) 2.04

Lost in Translation: Obstacles to Translational Medicine. J Transl Med (2004) 2.03

A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades. Proc Natl Acad Sci U S A (2002) 2.02

The role of BRAF V600 mutation in melanoma. J Transl Med (2012) 2.00

A signature of immune function genes associated with recurrence-free survival in breast cancer patients. Breast Cancer Res Treat (2011) 1.99

Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1. Proc Natl Acad Sci U S A (2011) 1.97

Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program. Blood (2009) 1.96

Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum Gene Ther (2002) 1.96

Genome-wide association mapping to candidate polymorphism resolution in the unsequenced barley genome. Proc Natl Acad Sci U S A (2010) 1.96

Gene expression profiling of cutaneous wound healing. J Transl Med (2007) 1.91

Two residues in the hemagglutinin of A/Fujian/411/02-like influenza viruses are responsible for antigenic drift from A/Panama/2007/99. Virology (2005) 1.91

The scorpions of Yunnan (China): updated identification key, new record and redescriptions of Euscorpiops kubani and E. shidian (Arachnida, Scorpiones). Zookeys (2011) 1.91

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors. J Clin Invest (2011) 1.90

Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy. Blood (2009) 1.88

Quantitative real-time PCR: a powerful ally in cancer research. Trends Mol Med (2003) 1.88

MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells. J Transl Med (2009) 1.85

What's next in translational medicine? Clin Sci (Lond) (2007) 1.85

In support of descriptive studies; relevance to translational research. J Transl Med (2007) 1.82

Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization. Proc Natl Acad Sci U S A (2008) 1.82

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest (2013) 1.81

Risk factors for sexually transmitted disease among rural-to-urban migrants in China: implications for HIV/sexually transmitted disease prevention. AIDS Patient Care STDS (2005) 1.81

Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma. Clin Cancer Res (2009) 1.81

A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers". J Transl Med (2008) 1.77

High prevalence of HIV-1 and hepatitis C virus coinfection among injection drug users in the southeastern region of Yunnan, China. J Acquir Immune Defic Syndr (2002) 1.75

Primary pleomorphic liposarcoma of pericardium. Interact Cardiovasc Thorac Surg (2010) 1.74

Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration. Genome Biol (2002) 1.74

Global transcriptome analysis of human bone marrow stromal cells (BMSC) reveals proliferative, mobile and interactive cells that produce abundant extracellular matrix proteins, some of which may affect BMSC potency. Cytotherapy (2011) 1.73

Immunotherapy for melanoma: current status and perspectives. J Immunother (2010) 1.72