PubRank

Yurii S Aulchenko

Author PubWeight™ 263.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
3 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
4 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
5 Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010 9.52
6 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
7 Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010 6.49
8 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
9 New loci associated with kidney function and chronic kidney disease. Nat Genet 2010 5.58
10 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 2012 5.48
11 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009 5.32
12 Genomewide association studies of stroke. N Engl J Med 2009 5.29
13 Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 2009 4.78
14 Predictive testing for complex diseases using multiple genes: fact or fiction? Genet Med 2006 4.48
15 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
16 A genomic background based method for association analysis in related individuals. PLoS One 2007 3.46
17 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
18 NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet 2009 3.18
19 The empirical power of rare variant association methods: results from sanger sequencing in 1,998 individuals. PLoS Genet 2012 2.86
20 Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med 2009 2.80
21 The effect of genetic drift in a young genetically isolated population. Ann Hum Genet 2005 2.75
22 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
23 Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum Mol Genet 2008 2.66
24 Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat Genet 2010 2.35
25 Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet 2010 2.30
26 Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA 2009 2.10
27 Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. Am J Hum Genet 2008 2.09
28 A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Hum Mol Genet 2009 2.03
29 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
30 A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nat Genet 2010 1.94
31 Rapid variance components-based method for whole-genome association analysis. Nat Genet 2012 1.89
32 A genome-wide association study of optic disc parameters. PLoS Genet 2010 1.87
33 Genome-wide association study of smoking initiation and current smoking. Am J Hum Genet 2009 1.87
34 Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes. J Hypertens 2007 1.85
35 Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet 2010 1.83
36 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet 2012 1.79
37 Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis 2009 1.78
38 PredictABEL: an R package for the assessment of risk prediction models. Eur J Epidemiol 2011 1.73
39 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
40 Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012 1.68
41 Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet 2010 1.67
42 A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci 2010 1.65
43 Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations. BMC Genet 2010 1.59
44 A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population. Am J Hum Genet 2007 1.55
45 Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet 2010 1.52
46 Migraine is not associated with enhanced atherosclerosis. Cephalalgia 2012 1.49
47 Genome-wide linkage analysis of serum creatinine in three isolated European populations. Kidney Int 2009 1.48
48 Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke 2009 1.47
49 Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet 2009 1.41
50 A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. Circ Cardiovasc Genet 2009 1.35
51 Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet 2012 1.33
52 Genetic contributions to glaucoma: heritability of intraocular pressure, retinal nerve fiber layer thickness, and optic disc morphology. Invest Ophthalmol Vis Sci 2007 1.31
53 Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays. Am J Hum Genet 2008 1.27
54 An approach for cutting large and complex pedigrees for linkage analysis. Eur J Hum Genet 2008 1.26
55 Genetic architecture of plasma adiponectin overlaps with the genetics of metabolic syndrome-related traits. Diabetes Care 2010 1.21
56 Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: the Erasmus Rucphen Family Study. Eur J Epidemiol 2007 1.20
57 Association of the gene encoding neurogranin with schizophrenia in males. J Psychiatr Res 2006 1.16
58 Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet 2012 1.14
59 Prevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families. Breast Cancer Res Treat 2010 1.08
60 Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins. Hum Mol Genet 2009 1.08
61 Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J 2011 1.08
62 Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis. J Hum Genet 2009 1.08
63 An R package "VariABEL" for genome-wide searching of potentially interacting loci by testing genotypic variance heterogeneity. BMC Genet 2012 1.05
64 Meta-analysis of genome-wide association for migraine in six population-based European cohorts. Eur J Hum Genet 2011 1.04
65 A study of the SORL1 gene in Alzheimer's disease and cognitive function. J Alzheimers Dis 2009 1.02
66 Maternal transmission of multiple sclerosis in a dutch population. Arch Neurol 2008 1.01
67 Rapid and robust association mapping of expression quantitative trait loci. BMC Proc 2007 1.01
68 A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. BMC Med Genet 2010 1.00
69 The apolipoprotein E gene and its age-specific effects on cognitive function. Neurobiol Aging 2008 0.99
70 A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genet 2011 0.97
71 Region-based association analysis of human quantitative traits in related individuals. PLoS One 2013 0.97
72 Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. Neurobiol Aging 2011 0.95
73 Association between type 2 diabetes loci and measures of fatness. PLoS One 2010 0.93
74 Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiol Aging 2010 0.93
75 The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease. Neurogenetics 2007 0.93
76 Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity. Stroke 2004 0.93
77 Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. Obesity (Silver Spring) 2009 0.93
78 Chromosome-wise dissection of the genome of the extremely big mouse line DU6i. Genetics 2005 0.92
79 Heritability estimates of body size in fetal life and early childhood. PLoS One 2012 0.91
80 Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease. J Neuroinflammation 2009 0.89
81 The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project. BMC Med Genet 2010 0.88
82 The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis. Ann Hum Genet 2010 0.86
83 Association of FGFR2 gene polymorphisms with the risk of breast cancer in population of West Siberia. Eur J Hum Genet 2009 0.85
84 Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum high-density lipoprotein cholesterol levels. J Clin Endocrinol Metab 2007 0.84
85 A powerful genome-wide feasible approach to detect parent-of-origin effects in studies of quantitative traits. Eur J Hum Genet 2009 0.84
86 A genome-wide screen for depression in two independent Dutch populations. Biol Psychiatry 2010 0.83
87 Detecting low frequent loss-of-function alleles in genome wide association studies with red hair color as example. PLoS One 2011 0.83
88 Genetic factors influence the clustering of depression among individuals with lower socioeconomic status. PLoS One 2009 0.83
89 Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study. J Neurol 2008 0.83
90 Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study. Psychiatr Genet 2008 0.83
91 Hearing impairment in Dutch patients with connexin 26 (GJB2) and connexin 30 (GJB6) mutations. Int J Pediatr Otorhinolaryngol 2005 0.83
92 Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol 2013 0.82
93 Role of shared genetic and environmental factors in symptoms of depression and body composition. Psychiatr Genet 2009 0.82
94 PedStr software for cutting large pedigrees for haplotyping, IBD computation and multipoint linkage analysis. Ann Hum Genet 2009 0.81
95 Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands. Hum Genet 2005 0.81
96 Genetic architecture of open angle glaucoma and related determinants. J Med Genet 2010 0.81
97 ParallABEL: an R library for generalized parallelization of genome-wide association studies. BMC Bioinformatics 2010 0.81
98 Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors. J Affect Disord 2009 0.81
99 Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project. J Neural Transm (Vienna) 2011 0.80
100 A genetic epidemiologic study of candidate genes involved in the optic nerve head morphology. Invest Ophthalmol Vis Sci 2012 0.80
101 Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. Eur J Hum Genet 2012 0.79
102 Low-density lipoprotein receptor mutations generate synthetic genome-wide associations. Eur J Hum Genet 2012 0.78
103 The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes. Diabetes 2006 0.78
104 Breaking loops in large complex pedigrees. Hum Hered 2007 0.78
105 Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2. Hum Genet 2012 0.77
106 Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project. Int J Mol Epidemiol Genet 2012 0.77
107 MQScore_SNP software for multipoint parametric linkage analysis of quantitative traits in large pedigrees. Ann Hum Genet 2010 0.76
108 A deletion in DJ-1 and the risk of dementia--a population-based survey. Neurosci Lett 2004 0.76
109 Solution for underflow problem in linkage and segregation analysis. Comput Biol Chem 2006 0.75
110 Ped_Outlier software for automatic identification of within-family outliers. Comput Biol Chem 2010 0.75