Published in PLoS One on January 18, 2010
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Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition. PLoS One (2011) 1.07
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Autophagy inhibition by sustained overproduction of IL6 contributes to arsenic carcinogenesis. Cancer Res (2014) 0.99
Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells. PLoS One (2010) 0.98
Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts. Autophagy (2012) 0.95
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Endothelial secreted factors suppress mitogen deprivation-induced autophagy and apoptosis in glioblastoma stem-like cells. PLoS One (2014) 0.86
The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death. Autophagy (2012) 0.86
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Autophagic activity in the mouse urinary bladder urothelium as a response to starvation. Protoplasma (2012) 0.77
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Rab7 is required for the normal progression of the autophagic pathway in mammalian cells. J Cell Sci (2004) 3.66
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Changes in the proteolytic activities of proteasomes and lysosomes in human fibroblasts produced by serum withdrawal, amino-acid deprivation and confluent conditions. Biochem J (2003) 1.89
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Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells. Cell Death Differ (2000) 1.64
Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells. J Neurochem (2005) 1.27
Fluorescence properties and staining behavior of monodansylpentane, a structural homologue of the lysosomotropic agent monodansylcadaverine. J Histochem Cytochem (2001) 1.07
Growth factor deprivation induces an alternative non-apoptotic death mechanism that is inhibited by Bcl2 in cells derived from neural precursor cells. J Hematother Stem Cell Res (2003) 0.97
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Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils. J Clin Invest (2005) 2.82
The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. Mol Cell (2004) 2.79
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Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members. J Cell Biol (2009) 1.83
Bax activation and mitochondrial insertion during apoptosis. Apoptosis (2007) 1.77
Nonredundant role of Bax and Bak in Bid-mediated apoptosis. Mol Cell Biol (2003) 1.52
Adhesion and osteogenic differentiation of human mesenchymal stem cells on titanium nanopores. Eur Cell Mater (2011) 1.52
Mitochondria as the target of the pro-apoptotic protein Bax. Biochim Biophys Acta (2006) 1.49
The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation. J Biol Chem (2013) 1.49
Deprivation indices, population health and geography: an evaluation of the spatial effectiveness of indices at multiple scales. J Urban Health (2007) 1.46
The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death. Cancer Res (2006) 1.45
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Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells. PLoS One (2010) 1.37
Influence of oxygen tension on CD133 phenotype in human glioma cell cultures. Cancer Lett (2007) 1.34
The N-terminal end of Bax contains a mitochondrial-targeting signal. J Biol Chem (2003) 1.29
Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption. Cancer Res (2007) 1.26
Ectopic bone formation by microporous calcium phosphate ceramic particles in sheep muscles. Bone (2005) 1.25
Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex. Oncogene (2005) 1.15
Assessment of a serum assay for quantification of abdominal aortic calcification. Arterioscler Thromb Vasc Biol (2006) 1.14
Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins. J Biol Chem (2003) 1.14
Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner. PLoS One (2012) 1.14
Distinct domains control the addressing and the insertion of Bax into mitochondria. J Biol Chem (2004) 1.11
Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process. Cancer Res (2010) 1.10
Novel biomaterials for bisphosphonate delivery. Biomaterials (2005) 1.04
The role of caspases in cell death and differentiation. Drug Resist Updat (2005) 1.03
The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients. Hum Mol Genet (2002) 1.03
Micro-architecture of calcium phosphate granules and fibrin glue composites for bone tissue engineering. Biomaterials (2005) 1.00
Basal autophagy decreased during the differentiation of human adult mesenchymal stem cells. Stem Cells Dev (2012) 0.99
Impact of pH on Bax alpha conformation, oligomerisation and mitochondrial integration. FEBS Lett (2004) 0.99
Dnmt1/Transcription factor interactions: an alternative mechanism of DNA methylation inheritance. Genes Cancer (2010) 0.99
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Carotid and femoral atherosclerotic plaques show different morphology. Atherosclerosis (2011) 0.96
Mitochondrial localization of the low level p53 protein in proliferative cells. Biochem Biophys Res Commun (2009) 0.96
Comparison of spheroids formed by rat glioma stem cells and neural stem cells reveals differences in glucose metabolism and promising therapeutic applications. J Biol Chem (2012) 0.96
Evidence for a mitochondrial localization of the retinoblastoma protein. BMC Cell Biol (2009) 0.95
Targeting metabolism to induce cell death in cancer cells and cancer stem cells. Int J Cell Biol (2013) 0.94
Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma. Oncotarget (2014) 0.94
The safety and efficacy of an injectable bone substitute in dental sockets demonstrated in a human clinical trial. Biomaterials (2007) 0.94
Yeast as a tool to study Bax/mitochondrial interactions in cell death. FEMS Yeast Res (2003) 0.92
Relationship between CT anthropometric measurements, adipokines and abdominal aortic calcification. Atherosclerosis (2007) 0.92
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The p18 truncated form of Bax behaves like a Bcl-2 homology domain 3-only protein. J Biol Chem (2003) 0.92
Substitutions of potentially phosphorylatable serine residues of Bax reveal how they may regulate its interaction with mitochondria. J Biol Chem (2007) 0.92
A triple-mutated allele of granzyme B incapable of inducing apoptosis. Proc Natl Acad Sci U S A (2003) 0.91
Investigation of the role of the C-terminus of Bax and of tc-Bid on Bax interaction with yeast mitochondria. Cell Death Differ (2003) 0.91
Infrared radiation affects the mitochondrial pathway of apoptosis in human fibroblasts. J Invest Dermatol (2004) 0.90
Impact of proapoptotic proteins Bax and Bak in tumor progression and response to treatment. Expert Rev Anticancer Ther (2003) 0.90
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Osteogenic properties of calcium phosphate ceramics and fibrin glue based composites. J Mater Sci Mater Med (2007) 0.89
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Differentiation-related response to DNA breaks in human mesenchymal stem cells. Stem Cells (2013) 0.88
Bone tissue formation in sheep muscles induced by a biphasic calcium phosphate ceramic and fibrin glue composite. J Mater Sci Mater Med (2007) 0.88
Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation. PLoS One (2011) 0.88
Cell-specific effects of TNF-α and IL-1β on alkaline phosphatase: implication for syndesmophyte formation and vascular calcification. Lab Invest (2011) 0.87
Proximity ligation in situ assay for monitoring the global DNA methylation in cells. BMC Biotechnol (2011) 0.87
Bax inserts into the mitochondrial outer membrane by different mechanisms. FEBS Lett (2008) 0.87
Control of Bax homodimerization by its carboxyl terminus. J Biol Chem (2007) 0.86
Calcium phosphate scaffold and bone marrow for bone reconstruction in irradiated area: a dog study. Bone (2005) 0.85
Evaluating potential spatial access to trauma center care by severely injured patients. Health Place (2012) 0.85
Specific inhibition of one DNMT1-including complex influences tumor initiation and progression. Clin Epigenetics (2013) 0.85
Alveolar bone regeneration for immediate implant placement using an injectable bone substitute: an experimental study in dogs. J Periodontol (2004) 0.84
HA14-1, a small molecule inhibitor of Bcl-2, bypasses chemoresistance in leukaemia cells. Leuk Res (2007) 0.84
MBCP biphasic calcium phosphate granules and tissucol fibrin sealant in rabbit femoral defects: the effect of fibrin on bone ingrowth. J Mater Sci Mater Med (2005) 0.84
Physico-chemical-mechanical and in vitro biological properties of calcium phosphate cements with doped amorphous calcium phosphates. Biomaterials (2006) 0.84
Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle. Cell Div (2012) 0.84
Activation of Bax by BH3 domains during apoptosis: the unfolding of a deadly plot. Cell Cycle (2005) 0.84
Pomegranate seed oil prevents bone loss in a mice model of osteoporosis, through osteoblastic stimulation, osteoclastic inhibition and decreased inflammatory status. J Nutr Biochem (2013) 0.84
Pomegranate and its derivatives can improve bone health through decreased inflammation and oxidative stress in an animal model of postmenopausal osteoporosis. Eur J Nutr (2014) 0.83
Increase in intracellular PGE2 induces apoptosis in Bax-expressing colon cancer cell. BMC Cancer (2011) 0.83
Mice with hypomorphic expression of the sodium-phosphate cotransporter PiT1/Slc20a1 have an unexpected normal bone mineralization. PLoS One (2013) 0.83
In vivo bone augmentation in an osteoporotic environment using bisphosphonate-loaded calcium deficient apatite. Biomaterials (2010) 0.83
C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1. J Biol Chem (2009) 0.83
Drug-eluting stents in bifurcations: bench study of strut deformation and coating lesions. Circ Cardiovasc Interv (2010) 0.83
Size dependent bioaccumulation and ecotoxicity of gold nanoparticles in an endobenthic invertebrate: the Tellinid clam Scrobicularia plana. Environ Pollut (2012) 0.82
Folic acid, vitamin B12, MTHFR genotypes, and plasma homocysteine. Clin Chem (2006) 0.82
In vitro biological effects of titanium rough surface obtained by calcium phosphate grid blasting. Biomaterials (2005) 0.82
The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response. PLoS One (2011) 0.82
A comparison between bone reconstruction following the use of mesenchymal stem cells and total bone marrow in association with calcium phosphate scaffold in irradiated bone. Biomaterials (2008) 0.82
Hybrid composites of calcium phosphate granules, fibrin glue, and bone marrow for skeletal repair. J Biomed Mater Res A (2007) 0.81