Published in JAMA on January 27, 2010
Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock (COIITSS) | NCT00320099
Design and conduct of the activated protein C and corticosteroids for human septic shock (APROCCHSS) trial. Ann Intensive Care (2016) 1.39
Lactate clearance for death prediction in severe sepsis or septic shock patients during the first 24 hours in Intensive Care Unit: an observational study. Ann Intensive Care (2013) 1.15
Corticosteroids for severe sepsis: an evidence-based guide for physicians. Ann Intensive Care (2011) 1.04
The Japanese guidelines for the management of sepsis. J Intensive Care (2014) 0.99
Glucocorticoids in sepsis: dissecting facts from fiction. Crit Care (2011) 0.97
Glucose control in critical care. World J Diabetes (2015) 0.93
Intensive insulin therapy in critically ill hospitalized patients: making it safe and effective. J Diabetes Sci Technol (2011) 0.92
Control groups in recent septic shock trials: a systematic review. Intensive Care Med (2016) 0.92
Quantifying the improvement in sepsis diagnosis, documentation, and coding: the marginal causal effect of year of hospitalization on sepsis diagnosis. Ann Epidemiol (2015) 0.90
Procalcitonin levels to guide antibiotic therapy in adults with non-microbiologically proven apparent severe sepsis: a randomised controlled trial. BMJ Open (2013) 0.88
Beneficial effects of stress-dose corticosteroid therapy in canines depend on the severity of staphylococcal pneumonia. Intensive Care Med (2012) 0.85
Management of sepsis in neutropenic patients: 2014 updated guidelines from the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO). Ann Hematol (2014) 0.84
Low-dose corticosteroid treatment and mortality in refractory abdominal septic shock after emergency laparotomy. Ann Intensive Care (2015) 0.84
Therapeutic strategies for high-dose vasopressor-dependent shock. Crit Care Res Pract (2013) 0.82
Association of hyperglycemia, glucocorticoids, and insulin use with morbidity and mortality in the pediatric intensive care unit. J Diabetes Sci Technol (2012) 0.82
Glucose Control in the ICU: A Continuing Story. J Diabetes Sci Technol (2016) 0.82
The effects of moderate-dose steroid therapy in sepsis: A placebo-controlled, randomized study. J Res Med Sci (2011) 0.81
Surviving Sepsis in High HIV Prevalence Settings. Med J Zambia (2010) 0.81
Associations between bolus infusion of hydrocortisone, glycemic variability and insulin infusion rate variability in critically Ill patients under moderate glycemic control. Ann Intensive Care (2015) 0.81
Hyperglycemia in aneurysmal subarachnoid hemorrhage: a potentially modifiable risk factor for poor outcome. J Cereb Blood Flow Metab (2010) 0.80
Clinical controversies in the management of critically ill patients with severe sepsis: resuscitation fluids and glucose control. Virulence (2013) 0.80
Intensive insulin therapy to control hyperglycemia in the critically ill: a look back at the evidence shapes the challenges ahead. Crit Care (2010) 0.79
What is the optimal blood glucose target in critically ill patients? A nested cohort study. Ann Thorac Med (2011) 0.79
Combined biomarkers discriminate a low likelihood of bacterial infection among surgical intensive care unit patients with suspected sepsis. Diagn Microbiol Infect Dis (2016) 0.78
Residual rates of mortality in patients with severe sepsis: a fatality or a new challenge? Ann Intensive Care (2013) 0.78
Hyporeninemic hypoaldosteronism and diabetes mellitus: Pathophysiology assumptions, clinical aspects and implications for management. World J Diabetes (2016) 0.78
Tight glycemic control in critically ill patients. JAMA (2010) 0.78
The Role of ACTH and Corticosteroids for Sepsis and Septic Shock: An Update. Front Endocrinol (Lausanne) (2016) 0.78
Intensive insulin therapy for septic patients: a meta-analysis of randomized controlled trials. Biomed Res Int (2014) 0.77
Tight glycemic control: what do we really know, and what should we expect? Crit Care (2010) 0.76
Low doses of fludrocortisone and hydrocortisone, alone or in combination, on vascular responsiveness to phenylephrine in healthy volunteers. Br J Clin Pharmacol (2013) 0.75
ACP Journal Club. Intensive insulin therapy did not reduce mortality more than conventional therapy in septic shock treated with corticosteroids. Ann Intern Med (2010) 0.75
Should glucocorticoid-induced hyperglycemia be treated in patients with septic shock? JAMA (2010) 0.75
Corticosteroids in septic shock: a systematic review and network meta-analysis. Crit Care (2017) 0.75
Acute severe illness in diabetes patients: is tolerating hyperglycemia beneficial? J Thorac Dis (2016) 0.75
Corticosteroids for sepsis: registry versus Cochrane systematic review! Crit Care (2010) 0.75
Hyperglycemia in Critically Ill Patients: Management and Prognosis. Med Arch (2015) 0.75
Mortality trends in U.S. adults with septic shock, 2005-2011: a serial cross-sectional analysis of nationally-representative data. BMC Infect Dis (2016) 0.75
A liberal glycemic target in critically ill patients with poorly controlled diabetes? Ann Transl Med (2016) 0.75
Experimental and clinical evidences for glucose control in intensive care: is infused glucose the key point for study interpretation? Crit Care (2014) 0.75
Hyperglycaemia in critically ill patients: the immune system's sweet tooth. Crit Care (2017) 0.75
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA (2002) 16.37
Hydrocortisone therapy for patients with septic shock. N Engl J Med (2008) 15.85
High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med (2015) 10.15
A communication strategy and brochure for relatives of patients dying in the ICU. N Engl J Med (2007) 10.13
Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med (2005) 6.52
Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Lancet (2009) 5.31
Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med (2008) 5.30
Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA (2003) 4.84
Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet (2007) 4.81
Family presence during cardiopulmonary resuscitation. N Engl J Med (2013) 4.74
A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med (2009) 4.13
Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study. Lancet (2012) 4.03
Diagnosis of adrenal insufficiency in severe sepsis and septic shock. Am J Respir Crit Care Med (2006) 4.02
Noninvasive ventilation improves preoxygenation before intubation of hypoxic patients. Am J Respir Crit Care Med (2006) 4.01
Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96
High level of burnout in intensivists: prevalence and associated factors. Am J Respir Crit Care Med (2007) 3.92
Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer. J Clin Oncol (2002) 3.69
Early use of the pulmonary artery catheter and outcomes in patients with shock and acute respiratory distress syndrome: a randomized controlled trial. JAMA (2003) 3.64
Hyperbaric oxygen therapy for radionecrosis of the jaw: a randomized, placebo-controlled, double-blind trial from the ORN96 study group. J Clin Oncol (2004) 3.64
Burnout syndrome in critical care nursing staff. Am J Respir Crit Care Med (2006) 3.62
Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med (2011) 3.43
Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Crit Care Med (2011) 3.34
Half the family members of intensive care unit patients do not want to share in the decision-making process: a study in 78 French intensive care units. Crit Care Med (2004) 3.31
The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock. Intensive Care Med (2009) 3.30
Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium--a groupe de recherche respiratoire en réanimation onco-hématologique study. J Clin Oncol (2013) 3.14
Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians. JAMA (2011) 3.11
Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol (2014) 3.06
Induced hypothermia in severe bacterial meningitis: a randomized clinical trial. JAMA (2013) 2.97
Influence of gender on the outcome of severe sepsis: a reappraisal. Chest (2007) 2.96
Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest: insights from the PROCAT (Parisian Region Out of hospital Cardiac ArresT) registry. Circ Cardiovasc Interv (2010) 2.91
Impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial. Intensive Care Med (2014) 2.89
An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units. Am J Respir Crit Care Med (2015) 2.86
DECOPI (DEsobstruction COronaire en Post-Infarctus): a randomized multi-centre trial of occluded artery angioplasty after acute myocardial infarction. Eur Heart J (2004) 2.85
Burnout syndrome among critical care healthcare workers. Curr Opin Crit Care (2007) 2.82
Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice. Exp Hematol (2004) 2.81
The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults. Am J Respir Crit Care Med (2002) 2.79
Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine. Resuscitation (2014) 2.76
Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis (2002) 2.71
Short- and long-term outcome in elderly patients after out-of-hospital cardiac arrest: a cohort study. Crit Care Med (2014) 2.70
Diagnostic strategy for hematology and oncology patients with acute respiratory failure: randomized controlled trial. Am J Respir Crit Care Med (2010) 2.62
Early tracheotomy versus prolonged endotracheal intubation in unselected severely ill ICU patients. Intensive Care Med (2008) 2.57
Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data. Crit Care Med (2008) 2.56
Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood (2008) 2.55
Systemic antifungal therapy in critically ill patients without invasive fungal infection*. Crit Care Med (2012) 2.55
Influence of overweight on ICU mortality: a prospective study. Chest (2004) 2.54
Fumagillin treatment of intestinal microsporidiosis. N Engl J Med (2002) 2.52
Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center. Crit Care Med (2012) 2.51
Clinical and electrophysiological predictors of respiratory failure in Guillain-Barré syndrome: a prospective study. Lancet Neurol (2006) 2.50
Extracorporeal membrane oxygenation for pandemic influenza A(H1N1)-induced acute respiratory distress syndrome: a cohort study and propensity-matched analysis. Am J Respir Crit Care Med (2012) 2.45
Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trial. Am J Respir Crit Care Med (2002) 2.44
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia. Blood (2013) 2.42
Predictors of noninvasive ventilation failure in patients with hematologic malignancy and acute respiratory failure. Crit Care Med (2008) 2.42
Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. BMJ (2004) 2.39
Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Respir Crit Care Med (2011) 2.39
Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease. Blood (2007) 2.36
High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: long-term results of a randomized control trial from the Group Myelome-Autogreffe. J Clin Oncol (2005) 2.35
Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med (2004) 2.33
ICU physicians should abandon the use of etomidate! Intensive Care Med (2005) 2.32
Tracheal intubation using the Airtraq in morbid obese patients undergoing emergency cesarean delivery. Anesthesiology (2007) 2.31
Predicting survival with good neurological recovery at hospital admission after successful resuscitation of out-of-hospital cardiac arrest: the OHCA score. Eur Heart J (2006) 2.30
Renal perfusion assessment by renal Doppler during fluid challenge in sepsis. Crit Care Med (2013) 2.28
Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest. J Am Coll Cardiol (2002) 2.27
Outcome of acute mesenteric ischemia in the intensive care unit: a retrospective, multicenter study of 780 cases. Intensive Care Med (2015) 2.25
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]. Crit Care (2004) 2.25
Important questions asked by family members of intensive care unit patients. Crit Care Med (2011) 2.22
Circulating vasopressin levels in septic shock. Crit Care Med (2003) 2.22
The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases. Blood (2008) 2.21
Can phrenic stimulation protect the diaphragm from mechanical ventilation-induced damage? Eur Respir J (2013) 2.21
Time course of organ dysfunction in thrombotic microangiopathy patients receiving either plasma perfusion or plasma exchange. Crit Care Med (2006) 2.21
Interobserver and intraobserver reproducibility in the histopathology of follicular thyroid carcinoma. Hum Pathol (2003) 2.20
Transient and Persistent Acute Kidney Injury and the Risk of Hospital Mortality in Critically Ill Patients: Results of a Multicenter Cohort Study. Crit Care Med (2015) 2.16
Epidemiology and outcome of thrombocytopenic patients in the intensive care unit: results of a prospective multicenter study. Intensive Care Med (2013) 2.16
Characteristics and prognosis of sudden cardiac death in Greater Paris: population-based approach from the Paris Sudden Death Expertise Center (Paris-SDEC). Intensive Care Med (2014) 2.16
Prognostic factors and outcome of human herpesvirus 8-associated primary effusion lymphoma in patients with AIDS. J Clin Oncol (2005) 2.16
Survival in neutropenic patients with severe sepsis or septic shock. Crit Care Med (2012) 2.15