Published in N Engl J Med on February 01, 2007
A Communication Strategy for Families of Patients Dying in the ICU | NCT00331877
End-of-life Decision-making in Patients With Sepsis-related Organ Failure (EIDECS) | NCT01247792
Family Information Management in the Intensive Care Unit (ICU-Families) | NCT02931851
Prospective Evaluation of Family Care Rituals in the ICU (FCR) | NCT02875912
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness | NCT02445937
Improving Patient and Family Centered Care in Advanced Critical Illness (PARTNER) | NCT01844492
Stress Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU | NCT04476914
Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA (2008) 11.32
The impact of advance care planning on end of life care in elderly patients: randomised controlled trial. BMJ (2010) 5.88
Expectations and outcomes of prolonged mechanical ventilation. Crit Care Med (2009) 3.77
Effect of a quality-improvement intervention on end-of-life care in the intensive care unit: a randomized trial. Am J Respir Crit Care Med (2010) 2.94
Practical guidance for evidence-based ICU family conferences. Chest (2008) 2.68
Models for structuring a clinical initiative to enhance palliative care in the intensive care unit: a report from the IPAL-ICU Project (Improving Palliative Care in the ICU). Crit Care Med (2010) 2.49
Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debate. Am J Respir Crit Care Med (2009) 2.46
A prognostic model for one-year mortality in patients requiring prolonged mechanical ventilation. Crit Care Med (2008) 2.44
Chronic critical illness. Am J Respir Crit Care Med (2010) 2.42
Voices of African American, Caucasian, and Hispanic surrogates on the burdens of end-of-life decision making. J Gen Intern Med (2008) 2.17
Posttraumatic stress and complicated grief in family members of patients in the intensive care unit. J Gen Intern Med (2008) 2.12
In their own words: patients and families define high-quality palliative care in the intensive care unit. Crit Care Med (2010) 2.08
A randomized trial of two methods to disclose prognosis to surrogate decision makers in intensive care units. Am J Respir Crit Care Med (2010) 2.07
ICU care associated with symptoms of depression and posttraumatic stress disorder among family members of patients who die in the ICU. Chest (2010) 1.98
Integrating palliative and critical care: evaluation of a quality-improvement intervention. Am J Respir Crit Care Med (2008) 1.96
How clinicians discuss critically ill patients' preferences and values with surrogates: an empirical analysis. Crit Care Med (2015) 1.82
Comparing clinician ratings of the quality of palliative care in the intensive care unit. Crit Care Med (2011) 1.81
Depressive symptoms in spouses of older patients with severe sepsis. Crit Care Med (2012) 1.78
Scope and outcomes of surrogate decision making among hospitalized older adults. JAMA Intern Med (2014) 1.77
I don't want to be the one saying 'we should just let him die': intrapersonal tensions experienced by surrogate decision makers in the ICU. J Gen Intern Med (2012) 1.76
Identifying family members who may struggle in the role of surrogate decision maker. Crit Care Med (2012) 1.75
Predictors of symptoms of posttraumatic stress and depression in family members after patient death in the ICU. Chest (2009) 1.74
Randomized Trial of Communication Facilitators to Reduce Family Distress and Intensity of End-of-Life Care. Am J Respir Crit Care Med (2016) 1.71
Hospital variation and temporal trends in palliative and end-of-life care in the ICU. Crit Care Med (2013) 1.70
Estimating the effect of palliative care interventions and advance care planning on ICU utilization: a systematic review. Crit Care Med (2015) 1.68
Families with limited English proficiency receive less information and support in interpreted intensive care unit family conferences. Crit Care Med (2009) 1.68
The effect of emotion and physician communication behaviors on surrogates' life-sustaining treatment decisions: a randomized simulation experiment. Crit Care Med (2013) 1.57
Pediatric intensive care unit family conferences: one mode of communication for discussing end-of-life care decisions. Pediatr Crit Care Med (2011) 1.53
Predictors and correlates of dissatisfaction with intensive care. Crit Care Med (2012) 1.53
Meeting standards of high-quality intensive care unit palliative care: clinical performance and predictors. Crit Care Med (2012) 1.52
Perceptions of "futile care" among caregivers in intensive care units. CMAJ (2007) 1.48
How the relationships between general practitioners and intensivists can be improved: the general practitioners' point of view. Crit Care (2010) 1.45
Time-Limited Trials of Intensive Care for Critically Ill Patients With Cancer: How Long Is Long Enough? JAMA Oncol (2016) 1.45
Development and validation of a printed information brochure for families of chronically critically ill patients. Crit Care Med (2012) 1.43
Neglect of quality-of-life considerations in intensive care unit family meetings for long-stay intensive care unit patients. Crit Care Med (2012) 1.43
Communication about chronic critical illness. Arch Intern Med (2007) 1.42
Prospective study of a proactive palliative care rounding intervention in a medical ICU. Intensive Care Med (2015) 1.40
Family Conferences in the Neonatal ICU: Observation of Communication Dynamics and Contributions. Pediatr Crit Care Med (2016) 1.40
Communication about cancer near the end of life. Cancer (2008) 1.40
Integrating palliative care into the PICU: a report from the Improving Palliative Care in the ICU Advisory Board. Pediatr Crit Care Med (2014) 1.39
Effectiveness trial of an intensive communication structure for families of long-stay ICU patients. Chest (2010) 1.38
Family member satisfaction with end-of-life decision making in the ICU. Chest (2008) 1.26
End-of-life care in the intensive care unit: can we simultaneously increase quality and reduce costs? Am J Respir Crit Care Med (2012) 1.20
Family meetings in palliative care: Multidisciplinary clinical practice guidelines. BMC Palliat Care (2008) 1.20
The intensive care unit family meeting: making it happen. J Crit Care (2009) 1.19
Duration of withdrawal of life support in the intensive care unit and association with family satisfaction. Am J Respir Crit Care Med (2008) 1.18
Physicians' experience with surrogate decision making for hospitalized adults. J Gen Intern Med (2009) 1.15
Integrating Palliative Care in the ICU: The Nurse in a Leading Role. J Hosp Palliat Nurs (2011) 1.15
Communication with relatives and collusion in palliative care: a cross-cultural perspective. Indian J Palliat Care (2009) 1.13
The changing role of palliative care in the ICU. Crit Care Med (2014) 1.10
Does palliative care improve quality? A survey of bereaved family members. J Pain Symptom Manage (2008) 1.09
The quality of care provided to hospitalized patients at the end of life. Arch Intern Med (2010) 1.07
Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med (2014) 1.05
Family meetings made simpler: a toolkit for the intensive care unit. J Crit Care (2009) 1.04
Improving medical communication with patients and families: Skills for a complex (and multilingual) clinical world. Can Respir J (2014) 1.04
Interprofessional communication skills training for serious illness: evaluation of a small-group, simulated patient intervention. J Palliat Med (2013) 1.03
Communication practices in physician decision-making for an unstable critically ill patient with end-stage cancer. J Palliat Med (2010) 1.03
Communication in critical care: family rounds in the intensive care unit. Am J Crit Care (2010) 0.99
Weighing the benefits and burdens of witnessed resuscitation. N Engl J Med (2013) 0.99
A systematic review of communication quality improvement interventions for patients with advanced and serious illness. J Gen Intern Med (2012) 0.98
Learned helplessness among families and surrogate decision-makers of patients admitted to medical, surgical, and trauma ICUs. Chest (2012) 0.98
Development and evaluation of an interprofessional communication intervention to improve family outcomes in the ICU. Contemp Clin Trials (2012) 0.96
Palliative care in COPD: an unmet area for quality improvement. Int J Chron Obstruct Pulmon Dis (2015) 0.93
Communicating with clinicians: the experiences of surrogate decision-makers for hospitalized older adults. J Am Geriatr Soc (2012) 0.92
CAESAR: a new tool to assess relatives' experience of dying and death in the ICU. Intensive Care Med (2016) 0.92
Is it safe? Talking to teens with HIV/AIDS about death and dying: a 3-month evaluation of Family Centered Advance Care (FACE) planning - anxiety, depression, quality of life. HIV AIDS (Auckl) (2010) 0.92
The quality of supportive care among inpatients dying with advanced cancer. Support Care Cancer (2012) 0.90
A universal decision support system. Addressing the decision-making needs of patients, families, and clinicians in the setting of critical illness. Am J Respir Crit Care Med (2014) 0.89
The healing power of listening in the ICU. N Engl J Med (2007) 0.89
The use and abuse of multiple outcomes in randomized controlled depression trials. Contemp Clin Trials (2010) 0.89
Family-centered care in the pediatric intensive care unit. Pediatr Clin North Am (2013) 0.89
Therapeutic Alliance between the Caregivers of Critical Illness Survivors and Intensive Care Unit Clinicians. Ann Am Thorac Soc (2015) 0.88
Emotional disorders in pairs of patients and their family members during and after ICU stay. PLoS One (2015) 0.88
Identifying elements of ICU care that families report as important but unsatisfactory: decision-making, control, and ICU atmosphere. Chest (2012) 0.87
A conceptual model of the role of communication in surrogate decision making for hospitalized adults. Patient Educ Couns (2011) 0.87
Visitation policies and practices in US ICUs. Crit Care (2013) 0.86
End-of-Life Care Interventions: An Economic Analysis. Ont Health Technol Assess Ser (2014) 0.86
Research priorities for geriatric palliative care: goals, values, and preferences. J Palliat Med (2013) 0.85
A brief educational intervention to teach residents shared decision making in the intensive care unit. J Palliat Med (2013) 0.85
Coping Strategies and Posttraumatic Stress Symptoms in Post-ICU Family Decision Makers. Crit Care Med (2015) 0.85
Clearance of fear memory from the hippocampus through neurogenesis by omega-3 fatty acids: a novel preventive strategy for posttraumatic stress disorder? Biopsychosoc Med (2011) 0.85
Intensive care unit visitation policies in Brazil: a multicenter survey. Rev Bras Ter Intensiva (2015) 0.85
Life-sustaining treatment decisions in the ICU for patients with ESLD: a prospective investigation. Res Nurs Health (2012) 0.84
[Palliative therapy concepts in intensive care medicine]. Anaesthesist (2017) 0.82
Preliminary data from an advanced dementia consult service: integrating research, education, and clinical expertise. J Am Geriatr Soc (2013) 0.82
Involvement of ICU families in decisions: fine-tuning the partnership. Ann Intensive Care (2014) 0.82
The use of family conferences in the pediatric intensive care unit. J Palliat Med (2013) 0.82
Improving social work in intensive care unit palliative care: results of a quality improvement intervention. J Palliat Med (2010) 0.82
Amniotic fluid embolism. Int J Crit Illn Inj Sci (2013) 0.81
Physician reimbursement for critical care services integrating palliative care for patients who are critically ill. Chest (2012) 0.81
The quality of dying and death: is it ready for use as an outcome measure? Chest (2013) 0.80
The importance and challenge of measuring family experience with end-of-life care in the ICU. Intensive Care Med (2016) 0.80
What information do parents need when facing end-of-life decisions for their child? A meta-synthesis of parental feedback. BMC Palliat Care (2015) 0.80
Fidelity to a behavioral intervention to improve goals of care decisions for nursing home residents with advanced dementia. Clin Trials (2016) 0.80
Limited family members/staff communication in intensive care units in the Czech and Slovak Republics considerably increases anxiety in patients' relatives--the DEPRESS study. BMC Psychiatry (2014) 0.80
Recognizing, naming, and measuring a family intensive care unit syndrome. Ann Am Thorac Soc (2014) 0.80
Impact of critical care medicine training programs' palliative care education and bedside tools on ICU use at the end of life. J Grad Med Educ (2014) 0.80
Integration of palliative care in chronic critical illness management. Respir Care (2012) 0.79
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA (2002) 16.37
Prone positioning in severe acute respiratory distress syndrome. N Engl J Med (2013) 12.37
High versus low blood-pressure target in patients with septic shock. N Engl J Med (2014) 7.37
Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med (2005) 6.52
Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Lancet (2009) 5.31
Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA (2003) 4.84
Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet (2007) 4.81
Family presence during cardiopulmonary resuscitation. N Engl J Med (2013) 4.74
Association between acute care and critical illness hospitalization and cognitive function in older adults. JAMA (2010) 4.36
Epidemiologic study of in-hospital cardiopulmonary resuscitation in the elderly. N Engl J Med (2009) 4.23
Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study. Lancet (2012) 4.03
High level of burnout in intensivists: prevalence and associated factors. Am J Respir Crit Care Med (2007) 3.92
Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American College [corrected] of Critical Care Medicine. Crit Care Med (2008) 3.85
Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer. J Clin Oncol (2002) 3.69
Early use of the pulmonary artery catheter and outcomes in patients with shock and acute respiratory distress syndrome: a randomized controlled trial. JAMA (2003) 3.64
Hyperbaric oxygen therapy for radionecrosis of the jaw: a randomized, placebo-controlled, double-blind trial from the ORN96 study group. J Clin Oncol (2004) 3.64
Burnout syndrome in critical care nursing staff. Am J Respir Crit Care Med (2006) 3.62
Expanding the paradigm of the physician's role in surrogate decision-making: an empirically derived framework. Crit Care Med (2010) 3.54
Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trial. JAMA (2010) 3.50
Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med (2011) 3.43
Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Crit Care Med (2011) 3.34
Half the family members of intensive care unit patients do not want to share in the decision-making process: a study in 78 French intensive care units. Crit Care Med (2004) 3.31
The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock. Intensive Care Med (2009) 3.30
Family satisfaction with family conferences about end-of-life care in the intensive care unit: increased proportion of family speech is associated with increased satisfaction. Crit Care Med (2004) 3.18
Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium--a groupe de recherche respiratoire en réanimation onco-hématologique study. J Clin Oncol (2013) 3.14
Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians. JAMA (2011) 3.11
Clinician statements and family satisfaction with family conferences in the intensive care unit. Crit Care Med (2006) 3.08
Open lung biopsy in nonresolving ARDS frequently identifies diffuse alveolar damage regardless of the severity stage and may have implications for patient management. Intensive Care Med (2014) 3.03
Induced hypothermia in severe bacterial meningitis: a randomized clinical trial. JAMA (2013) 2.97
Influence of gender on the outcome of severe sepsis: a reappraisal. Chest (2007) 2.96
Prognostication during physician-family discussions about limiting life support in intensive care units. Crit Care Med (2007) 2.96
Impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial. Intensive Care Med (2014) 2.89
An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units. Am J Respir Crit Care Med (2015) 2.86
DECOPI (DEsobstruction COronaire en Post-Infarctus): a randomized multi-centre trial of occluded artery angioplasty after acute myocardial infarction. Eur Heart J (2004) 2.85
Burnout syndrome among critical care healthcare workers. Curr Opin Crit Care (2007) 2.82
Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice. Exp Hematol (2004) 2.81
The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults. Am J Respir Crit Care Med (2002) 2.79
Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis (2002) 2.71
Quality of dying in the ICU: is it worse for patients admitted from the hospital ward compared to those admitted from the emergency department? Intensive Care Med (2014) 2.71
Diagnostic strategy for hematology and oncology patients with acute respiratory failure: randomized controlled trial. Am J Respir Crit Care Med (2010) 2.62
Decisions to limit life-sustaining treatment for critically ill patients who lack both decision-making capacity and surrogate decision-makers. Crit Care Med (2006) 2.61
Discrepancies between perceptions by physicians and nursing staff of intensive care unit end-of-life decisions. Am J Respir Crit Care Med (2003) 2.57
Toward shared decision making at the end of life in intensive care units: opportunities for improvement. Arch Intern Med (2007) 2.56
Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data. Crit Care Med (2008) 2.56
Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood (2008) 2.55
Fumagillin treatment of intestinal microsporidiosis. N Engl J Med (2002) 2.52
Year in review in Intensive Care Medicine 2011: III. ARDS and ECMO, weaning, mechanical ventilation, noninvasive ventilation, pediatrics and miscellanea. Intensive Care Med (2012) 2.52
L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study. Crit Care Med (2006) 2.51
Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center. Crit Care Med (2012) 2.51
Prospective study of arterial and central venous catheter colonization and of arterial- and central venous catheter-related bacteremia in intensive care units. Crit Care Med (2005) 2.49
Models for structuring a clinical initiative to enhance palliative care in the intensive care unit: a report from the IPAL-ICU Project (Improving Palliative Care in the ICU). Crit Care Med (2010) 2.49
Seeking worldwide professional consensus on the principles of end-of-life care for the critically ill. The Consensus for Worldwide End-of-Life Practice for Patients in Intensive Care Units (WELPICUS) study. Am J Respir Crit Care Med (2014) 2.46
Extracorporeal membrane oxygenation for pandemic influenza A(H1N1)-induced acute respiratory distress syndrome: a cohort study and propensity-matched analysis. Am J Respir Crit Care Med (2012) 2.45
Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trial. Am J Respir Crit Care Med (2002) 2.44