Published in Lancet on August 25, 2007
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis. Crit Care Med (2008) 3.73
Recommendations for sepsis management in resource-limited settings. Intensive Care Med (2012) 2.03
Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Crit Care (2009) 1.87
Part 10: Pediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation (2010) 1.50
The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg (2017) 1.38
Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study. Crit Care (2013) 1.31
WSES consensus conference: Guidelines for first-line management of intra-abdominal infections. World J Emerg Surg (2011) 1.29
Advances in the management of sepsis and the understanding of key immunologic defects. Anesthesiology (2011) 1.21
Catecholamine treatment for shock--equally good or bad? Lancet (2007) 1.13
Timing of vasopressor initiation and mortality in septic shock: a cohort study. Crit Care (2014) 1.05
Surviving sepsis: going beyond the guidelines. Ann Intensive Care (2011) 1.02
Diagnosis and treatment of severe sepsis. Crit Care (2007) 1.01
The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients. Intensive Care Med (2010) 0.95
Timing of antibiotics, volume, and vasoactive infusions in children with sepsis admitted to intensive care. Crit Care (2015) 0.95
Severe sepsis and septic shock: management and performance improvement. Virulence (2013) 0.94
Use of inotropes and vasopressor agents in critically ill patients. Br J Pharmacol (2012) 0.93
Control groups in recent septic shock trials: a systematic review. Intensive Care Med (2016) 0.92
Quantifying the improvement in sepsis diagnosis, documentation, and coding: the marginal causal effect of year of hospitalization on sepsis diagnosis. Ann Epidemiol (2015) 0.90
Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status. Crit Care (2009) 0.89
Vasopressors for the Treatment of Septic Shock: Systematic Review and Meta-Analysis. PLoS One (2015) 0.88
Procalcitonin levels to guide antibiotic therapy in adults with non-microbiologically proven apparent severe sepsis: a randomised controlled trial. BMJ Open (2013) 0.88
Therapeutic plasma exchange as rescue therapy in severe sepsis and septic shock: retrospective observational single-centre study of 23 patients. BMC Anesthesiol (2014) 0.87
Personalizing blood pressure management in septic shock. Ann Intensive Care (2015) 0.86
Pediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Pediatrics (2010) 0.85
Sepsis and ARDS: The Dark Side of Histones. Mediators Inflamm (2015) 0.83
Therapeutic strategies for high-dose vasopressor-dependent shock. Crit Care Res Pract (2013) 0.82
An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial. Trials (2014) 0.82
Another nail in the hammer's coffin? Crit Care (2011) 0.82
[Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy]. Anaesthesist (2017) 0.82
Disturbances of the hypothalamic-pituitary-adrenal axis and plasma electrolytes during experimental sepsis. Ann Intensive Care (2011) 0.81
Use of pressors in the management of septic shock. Lancet (2007) 0.79
Catecholamine dosing and survival in adult intensive care unit patients. World J Surg (2013) 0.79
Norepinephrine supplemented with dobutamine or epinephrine for the cardiovascular support of patients with septic shock. Indian J Crit Care Med (2012) 0.79
Residual rates of mortality in patients with severe sepsis: a fatality or a new challenge? Ann Intensive Care (2013) 0.78
Vasopressors in septic shock: a systematic review and network meta-analysis. Ther Clin Risk Manag (2015) 0.78
Pharmacological optimization of tissue perfusion. Br J Anaesth (2009) 0.78
Long-term mortality after critical care: what is the starting point? Crit Care (2013) 0.77
Challenges with Diagnosing and Managing Sepsis in Older Adults. Expert Rev Anti Infect Ther (2016) 0.76
Norepinephrine: more of a neurohormone than a vasopressor. Crit Care (2010) 0.76
Vascular Dilation, Tachycardia, and Increased Inotropy Occur Sequentially with Increasing Epinephrine Dose Rate, Plasma and Myocardial Concentrations, and cAMP. Heart Lung Circ (2015) 0.75
Adrenaline aggravates lung injury caused by liver ischemia-reperfusion and high-tidal-volume ventilation in rats. J Intensive Care (2016) 0.75
Use of pressors in the management of septic shock. Lancet (2007) 0.75
Recently published papers: more about EGDT, experimental therapies and some inconvenient truths. Crit Care (2007) 0.75
Choice of vasopressor in septic shock: does it matter? Crit Care (2007) 0.75
Epinephrine: what place in sepsis? Curr Infect Dis Rep (2008) 0.75
Vasoactive agents for the treatment of sepsis. Ann Transl Med (2016) 0.75
Vasopressor and Inotropic Management Of Patients With Septic Shock. P T (2015) 0.75
Does the Mean Arterial Pressure Influence Mortality Rate in Patients with Acute Hypoxemic Respiratory Failure under Mechanical Ventilation? Tuberc Respir Dis (Seoul) (2015) 0.75
Epinephrine: is it really the black sheep of vasoactive agents? Crit Care (2010) 0.75
Genomics and pharmacogenomics of sepsis: so close and yet so far. Crit Care (2016) 0.75
Comparative safety and efficacy of vasopressors for mortality in septic shock: A network meta-analysis. J Intensive Care Soc (2015) 0.75
Cerebral Blood Flow Autoregulation in Sepsis for the Intensivist: Why Its Monitoring May Be the Future of Individualized Care. J Intensive Care Med (2016) 0.75
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA (2002) 16.37
High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med (2015) 10.15
A communication strategy and brochure for relatives of patients dying in the ICU. N Engl J Med (2007) 10.13
High versus low blood-pressure target in patients with septic shock. N Engl J Med (2014) 7.37
Septic shock. Lancet (2005) 6.67
Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med (2005) 6.52
Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumonia. N Engl J Med (2004) 5.74
Use of high-flow nasal cannula oxygen therapy to prevent desaturation during tracheal intubation of intensive care patients with mild-to-moderate hypoxemia. Crit Care Med (2015) 5.40
Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Lancet (2009) 5.31
Family presence during cardiopulmonary resuscitation. N Engl J Med (2013) 4.74
Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review. JAMA (2009) 4.73
A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med (2009) 4.13
DALI: defining antibiotic levels in intensive care unit patients: are current β-lactam antibiotic doses sufficient for critically ill patients? Clin Infect Dis (2014) 3.99
High level of burnout in intensivists: prevalence and associated factors. Am J Respir Crit Care Med (2007) 3.92
12-h pretreatment with methylprednisolone versus placebo for prevention of postextubation laryngeal oedema: a randomised double-blind trial. Lancet (2007) 3.80
Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function. Crit Care Med (2005) 3.68
Burnout syndrome in critical care nursing staff. Am J Respir Crit Care Med (2006) 3.62
Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trial. JAMA (2010) 3.50
Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med (2011) 3.43
Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Crit Care Med (2011) 3.34
Combination biomarkers to diagnose sepsis in the critically ill patient. Am J Respir Crit Care Med (2012) 3.24
Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians. JAMA (2011) 3.11
Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis. Ann Intern Med (2004) 3.03
American College of Chest Physicians/La Société de Réanimation de Langue Française statement on competence in critical care ultrasonography. Chest (2009) 3.03
Induced hypothermia in severe bacterial meningitis: a randomized clinical trial. JAMA (2013) 2.97
Influence of gender on the outcome of severe sepsis: a reappraisal. Chest (2007) 2.96
Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients*. Crit Care Med (2014) 2.86
An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units. Am J Respir Crit Care Med (2015) 2.86
High-altitude pulmonary edema at moderate altitude (< 2,400 m; 7,870 feet): a series of 52 patients. Chest (2003) 2.82
Burnout syndrome among critical care healthcare workers. Curr Opin Crit Care (2007) 2.82
A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J Exp Med (2004) 2.80
De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial. Intensive Care Med (2014) 2.77
Effect of low doses of corticosteroids in septic shock patients with or without early acute respiratory distress syndrome. Crit Care Med (2006) 2.69
Amphotericin B deoxycholate for candidiasis in intensive care unit patients revisited: medical, ethical, and financial implications. Am J Respir Crit Care Med (2013) 2.63
Protective ventilation influences systemic inflammation after esophagectomy: a randomized controlled study. Anesthesiology (2006) 2.62
Early tracheotomy versus prolonged endotracheal intubation in unselected severely ill ICU patients. Intensive Care Med (2008) 2.57
Right ventricular function during high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome. Crit Care Med (2012) 2.56
Effect of neuromuscular blocking agents on gas exchange in patients presenting with acute respiratory distress syndrome. Crit Care Med (2004) 2.55
Systemic antifungal therapy in critically ill patients without invasive fungal infection*. Crit Care Med (2012) 2.55
Ultrasonographic identification and semiquantitative assessment of unloculated pleural effusions in critically ill patients by residents after a focused training. Intensive Care Med (2014) 2.53
Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center. Crit Care Med (2012) 2.51
Humidified high flow nasal oxygen during respiratory failure in the emergency department: feasibility and efficacy. Respir Care (2012) 2.48
Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trial. Am J Respir Crit Care Med (2002) 2.44
Predictors of noninvasive ventilation failure in patients with hematologic malignancy and acute respiratory failure. Crit Care Med (2008) 2.42
Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. BMJ (2004) 2.39
Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Respir Crit Care Med (2011) 2.39
Ventilator-associated pneumonia: breaking the vicious circle of antibiotic overuse. Crit Care Med (2007) 2.38
Renal effects of norepinephrine in septic and nonseptic patients. Chest (2004) 2.37
Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study. Lancet (2005) 2.35
The effect of waiving consent on enrollment in a sepsis trial. Intensive Care Med (2004) 2.34
Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med (2004) 2.33
Impact of the administration of probiotics on mortality in critically ill adult patients: a meta-analysis of randomized controlled trials. Chest (2013) 2.30
Renal perfusion assessment by renal Doppler during fluid challenge in sepsis. Crit Care Med (2013) 2.28
Oral nystatin prophylaxis of Candida spp. colonization in ventilated critically ill patients. Intensive Care Med (2005) 2.27
Outcome of acute mesenteric ischemia in the intensive care unit: a retrospective, multicenter study of 780 cases. Intensive Care Med (2015) 2.25
Important questions asked by family members of intensive care unit patients. Crit Care Med (2011) 2.22
Time course of organ dysfunction in thrombotic microangiopathy patients receiving either plasma perfusion or plasma exchange. Crit Care Med (2006) 2.21
CHOP alone compared with CHOP plus radiotherapy for localized aggressive lymphoma in elderly patients: a study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol (2007) 2.17
Incidence and prognosis of sustained arrhythmias in critically ill patients. Am J Respir Crit Care Med (2008) 2.17
Survival in neutropenic patients with severe sepsis or septic shock. Crit Care Med (2012) 2.15
Risk factors for late-onset ventilator-associated pneumonia in trauma patients receiving selective digestive decontamination. Intensive Care Med (2004) 2.13
Type III procollagen is a reliable marker of ARDS-associated lung fibroproliferation. Intensive Care Med (2014) 2.12
Symptoms of anxiety and depression in family members of intensive care unit patients before discharge or death. A prospective multicenter study. J Crit Care (2005) 2.12
Calibration and discrimination by daily Logistic Organ Dysfunction scoring comparatively with daily Sequential Organ Failure Assessment scoring for predicting hospital mortality in critically ill patients. Crit Care Med (2002) 2.07
Candida as a risk factor for mortality in peritonitis. Crit Care Med (2006) 2.07
Randomized controlled trial of sevoflurane for intubation in neonates. Paediatr Anaesth (2007) 2.06
Early antibiotic treatment for BAL-confirmed ventilator-associated pneumonia: a role for routine endotracheal aspirate cultures. Chest (2005) 2.05
Airway fungal colonization compromises the immune system allowing bacterial pneumonia to prevail. Crit Care Med (2013) 2.05
The ICU trial: a new admission policy for cancer patients requiring mechanical ventilation. Crit Care Med (2007) 2.05
Time-course of sTREM (soluble triggering receptor expressed on myeloid cells)-1, procalcitonin, and C-reactive protein plasma concentrations during sepsis. Crit Care Med (2005) 2.02
Terlipressin or norepinephrine in hyperdynamic septic shock: a prospective, randomized study. Crit Care Med (2005) 1.95
Active cytomegalovirus infection is common in mechanically ventilated medical intensive care unit patients. Crit Care Med (2009) 1.92
Early identification of patients at risk for difficult intubation in the intensive care unit: development and validation of the MACOCHA score in a multicenter cohort study. Am J Respir Crit Care Med (2013) 1.90
Echocardiography in the intensive care unit: from evolution to revolution? Intensive Care Med (2007) 1.90
Empirical antimicrobial therapy of septic shock patients: adequacy and impact on the outcome. Crit Care Med (2003) 1.89
Decompressive craniectomy for severe traumatic brain injury: Evaluation of the effects at one year. Crit Care Med (2003) 1.88
Tracheostomy does not improve the outcome of patients requiring prolonged mechanical ventilation: a propensity analysis. Crit Care Med (2007) 1.87
Severe imported falciparum malaria: a cohort study in 400 critically ill adults. PLoS One (2010) 1.86
Selected medical errors in the intensive care unit: results of the IATROREF study: parts I and II. Am J Respir Crit Care Med (2009) 1.85
NH2 terminal pro-brain natriuretic peptide plasma level as an early marker of prognosis and cardiac dysfunction in septic shock patients. Crit Care Med (2005) 1.85
On the physiologic and clinical relevance of lung-borne cytokines during ventilator-induced lung injury. Am J Respir Crit Care Med (2003) 1.84
Impact of adverse events on outcomes in intensive care unit patients. Crit Care Med (2008) 1.84