Published in J Biol Chem on January 27, 2010
Controlling reaction specificity in pyridoxal phosphate enzymes. Biochim Biophys Acta (2011) 1.06
The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design. BMC Microbiol (2011) 0.91
Roles of quaternary structure and cysteine residues in the activity of human serine racemase. BMC Biochem (2011) 0.83
Crystal structure of Escherichia coli diaminopropionate ammonia-lyase reveals mechanism of enzyme activation and catalysis. J Biol Chem (2012) 0.82
D-Serine Production, Degradation, and Transport in ALS: Critical Role of Methodology. Neurol Res Int (2012) 0.81
Structural and mutational studies on substrate specificity and catalysis of Salmonella typhimurium D-cysteine desulfhydrase. PLoS One (2012) 0.81
Serine racemase: a key player in apoptosis and necrosis. Front Synaptic Neurosci (2014) 0.78
Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species. J Neurosci Res (2012) 0.76
A short history of SHELX. Acta Crystallogr A (2007) 7339.18
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
Phaser crystallographic software. J Appl Crystallogr (2007) 108.34
Automated protein model building combined with iterative structure refinement. Nat Struct Biol (1999) 27.52
The finer things in X-ray diffraction data collection. Acta Crystallogr D Biol Crystallogr (1999) 19.10
Methods used in the structure determination of bovine mitochondrial F1 ATPase. Acta Crystallogr D Biol Crystallogr (1996) 11.90
The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science (1997) 9.21
Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature (1987) 8.89
Glia-derived D-serine controls NMDA receptor activity and synaptic memory. Cell (2006) 4.53
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A (2000) 3.71
Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science (1988) 3.54
Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine. Proc Natl Acad Sci U S A (2003) 2.35
Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proc Natl Acad Sci U S A (1999) 2.27
D-serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J Neurosci (1997) 1.93
Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature (1997) 1.90
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior. Mol Psychiatry (2008) 1.88
Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration. J Neurochem (1995) 1.79
NMDA- and beta-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice. J Neurosci (2008) 1.27
Direct calcium binding results in activation of brain serine racemase. J Biol Chem (2002) 1.22
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity. Biochemistry (2005) 1.07
Crystal structure of serine dehydratase from rat liver. Biochemistry (2003) 1.04
Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane. Proc Natl Acad Sci U S A (2009) 1.02
D-amino acids in the brain: structure and function of pyridoxal phosphate-dependent amino acid racemases. FEBS J (2008) 0.88
Involvement of D-amino acid oxidase in elimination of D-serine in mouse brain. Experientia (1992) 0.87
Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. J Biol Chem (2009) 0.86
Recombinant human serine racemase: enzymologic characterization and comparison with its mouse ortholog. Protein Expr Purif (2008) 0.83
Crystal structure of the pyridoxal-5'-phosphate-dependent serine dehydratase from human liver. Protein Sci (2005) 0.83
Structure, assembly, and mechanism of a PLP-dependent dodecameric L-aspartate beta-decarboxylase. Structure (2009) 0.79
CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science (2010) 3.17
In situ macromolecular crystallography using microbeams. Acta Crystallogr D Biol Crystallogr (2012) 1.94
Anthropometric assessment of 10-y changes in body composition in the elderly. Am J Clin Nutr (2004) 1.92
State-dependent Ras signaling and AMPA receptor trafficking. Genes Dev (2005) 1.86
The noninvasive staging of non-small cell lung cancer: the guidelines. Chest (2003) 1.57
MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes. J Biol Chem (2003) 1.37
Foreskin cutting beliefs and practices and the acceptability of male circumcision for HIV prevention in Papua New Guinea. BMC Public Health (2013) 1.25
Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors. Neuron (2003) 1.21
Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation. J Neurosci (2006) 1.13
Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors. PLoS Biol (2005) 1.07
The histamine H3 receptor as a therapeutic drug target for CNS disorders. Drug Discov Today (2009) 1.06
Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics. J Mol Med (Berl) (2002) 1.05
Co-isolation of Bartonella henselae and Bartonella vinsonii subsp. berkhoffii from blood, joint and subcutaneous seroma fluids from two naturally infected dogs. Vet Microbiol (2009) 1.04
Lung Organ Failure Score (LOFS): probability of severe pulmonary organ failure after multiple injuries including chest trauma. Injury (2011) 0.94
The implications of groundwater velocity variations on microbial transport and wellhead protection - review of field evidence. FEMS Microbiol Ecol (2004) 0.91
Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes. Biochemistry (2010) 0.90
Crystal engineering yields crystals of cyclophilin D diffracting to 1.7 A resolution. Acta Crystallogr D Biol Crystallogr (2005) 0.89
Impaired reproductive behavior by lack of GluR-B containing AMPA receptors but not of NMDA receptors in hypothalamic and septal neurons. Mol Endocrinol (2005) 0.89
Evaluation of a high-throughput fluorescence assay method for HERG potassium channel inhibition. J Biomol Screen (2005) 0.89
Primary pulmonary mucinous cystadenocarcinoma presenting as a complex bronchocele: a case report. J Med Case Rep (2009) 0.89
Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease. J Med Chem (2012) 0.87
Fragment-based discovery of BACE1 inhibitors using functional assays. Biochemistry (2009) 0.86
Assay development and data analysis of receptor-ligand binding based on scintillation proximity assay. Metab Eng (2005) 0.85
Opioid receptors modulate recovery from consummatory successive negative contrast. Behav Brain Res (2005) 0.85
Differential GABAA receptor clustering determines GABA synapse plasticity in rat oxytocin neurons around parturition and the onset of lactation. Mol Cell Neurosci (2005) 0.84
Using high-throughput in situ plate screening to evaluate the effect of dehydration on protein crystals. Acta Crystallogr D Biol Crystallogr (2013) 0.84
Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett (2010) 0.83
A high-throughput functional assay for characterization of gamma-aminobutyric acid(A) channel modulators using cryopreserved transiently transfected cells. Assay Drug Dev Technol (2008) 0.82
Discovery of a novel Hsp90 inhibitor by fragment linking. ChemMedChem (2010) 0.82
Systemic transplantation of progenitor cells accelerates wound epithelialization and neovascularization in the hairless mouse ear wound model. J Surg Res (2009) 0.82
Fragment-based identification of Hsp90 inhibitors. ChemMedChem (2009) 0.82
Cross-linking of protein crystals as an aid in the generation of binary protein-ligand crystal complexes, exemplified by the human PDE10a-papaverine structure. Acta Crystallogr D Biol Crystallogr (2009) 0.82
HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery. Curr Opin Drug Discov Devel (2003) 0.81
Epidemiology and outcomes associated with surgical site infection following bariatric surgery. Am J Infect Control (2012) 0.80
Clara cell protein 16: A biomarker for detecting secondary respiratory complications in patients with multiple injuries. J Trauma Acute Care Surg (2012) 0.79
Development of LC/MS/MS, high-throughput enzymatic and cellular assays for the characterization of compounds that inhibit kynurenine monooxygenase (KMO). J Biomol Screen (2013) 0.79
Retrospective audit of postnatal attendance for Aboriginal and Torres Strait Islander women attending a community-controlled health service in north Queensland. Aust Fam Physician (2015) 0.78
Using electrophysiology and in silico three-dimensional modeling to reduce human Ether-à-go-go related gene K(+) channel inhibition in a histamine H3 receptor antagonist program. Assay Drug Dev Technol (2010) 0.78
Vitamin C protects low-density lipoprotein from homocysteine-mediated oxidation. Free Radic Biol Med (2003) 0.78
GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.77
Amphipol-trapped ExbB-ExbD membrane protein complex from Escherichia coli: a biochemical and structural case study. J Membr Biol (2014) 0.77
Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone. Mediators Inflamm (2013) 0.77
High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand. Protein Sci (2010) 0.77
GluA1 and its PDZ-interaction: a role in experience-dependent behavioral plasticity in the forced swim test. Neurobiol Dis (2012) 0.76
Cell membrane modification for rapid display of bi-functional peptides: a novel approach to reduce complement activation. Open Cardiovasc Med J (2010) 0.76
Morpholine containing CB2 selective agonists. Bioorg Med Chem Lett (2009) 0.75
Process development for functional membrane receptor production in mammalian cells. Cytotechnology (2002) 0.75
High-throughput detection of submicroscopic deletions and methylation status at 15q11-q13 by a photo-cross-linking oligonucleotide hybridization assay. Clin Chem (2002) 0.75
Urine sediment from a Chihuahua. Vet Clin Pathol (2005) 0.75
Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity. Bioorg Med Chem Lett (2008) 0.75
What to do if you are referred to the NMC. Nurs Times (2014) 0.75
IT PAYS TO BEHAVE LIKE AN INVESTMENT PARTNER. Health Serv J (2015) 0.75
E. coli O157 persistence in the environment. Microbiology (2002) 0.75
Ion channel screening technologies: will they revolutionize drug discovery? Drug Discov Today (2002) 0.75
My experiences as a practice owner with a substantial NHS sedation contract. SAAD Dig (2009) 0.75
Photocrosslinking oligonucleotide hybridization assay for concurrent gene dosage and CpG methylation analysis. Methods Mol Biol (2004) 0.75
Detection of the factor V Leiden mutation by a modified photo-cross-linking oligonucleotide hybridization assay. Clin Chem (2003) 0.75
Resolution of diabetes after bariatric surgery among predominantly African-American patients: race has no effect in remission of diabetes after bariatric surgery. Obes Surg (2014) 0.75
Convergent radial tracing of viral and solute transport in gneiss saprolite. Ground Water (2009) 0.75
HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives. Bioorg Med Chem Lett (2009) 0.75