Published in DNA Repair (Amst) on February 01, 2010
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. DNA Repair (Amst) (2010) 1.71
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
The MRN complex in double-strand break repair and telomere maintenance. FEBS Lett (2010) 1.53
Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair. Genes Dev (2011) 1.46
Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation. Mutat Res (2010) 1.20
The spatial organization of non-homologous end joining: from bridging to end joining. DNA Repair (Amst) (2014) 0.99
Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates. Proc Natl Acad Sci U S A (2013) 0.93
The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining. Nat Commun (2014) 0.91
The multifunctional SNM1 gene family: not just nucleases. Future Oncol (2010) 0.91
Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ. Antioxid Redox Signal (2010) 0.90
Purification and characterization of exonuclease-free Artemis: Implications for DNA-PK-dependent processing of DNA termini in NHEJ-catalyzed DSB repair. DNA Repair (Amst) (2010) 0.88
A hypomorphic Artemis human disease allele causes aberrant chromosomal rearrangements and tumorigenesis. Hum Mol Genet (2010) 0.85
Restoration of G1 chemo/radioresistance and double-strand-break repair proficiency by wild-type but not endonuclease-deficient Artemis. Nucleic Acids Res (2011) 0.85
Non-homologous DNA end joining and alternative pathways to double-strand break repair. Nat Rev Mol Cell Biol (2017) 0.85
Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer. Genet Mol Biol (2015) 0.84
Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity. J Biol Chem (2014) 0.83
Unifying the DNA End-processing Roles of the Artemis Nuclease: KU-DEPENDENT ARTEMIS RESECTION AT BLUNT DNA ENDS. J Biol Chem (2015) 0.80
Efficient Rejoining of DNA Double-Strand Breaks despite Increased Cell-Killing Effectiveness following Spread-Out Bragg Peak Carbon-Ion Irradiation. Front Oncol (2016) 0.77
Structure-Specific nuclease activities of Artemis and the Artemis: DNA-PKcs complex. Nucleic Acids Res (2016) 0.77
Linkage of catalysis and 5' end recognition in ribonuclease RNase J. Nucleic Acids Res (2015) 0.75
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell (2002) 6.34
The mechanism of human nonhomologous DNA end joining. J Biol Chem (2007) 5.02
Binding properties of replication protein A from human and yeast cells. Mol Cell Biol (1992) 2.66
DNA-PK autophosphorylation facilitates Artemis endonuclease activity. EMBO J (2006) 2.48
The DNA-dependent protein kinase: the director at the end. Immunol Rev (2004) 2.20
DNA-PK: the means to justify the ends? Adv Immunol (2008) 2.14
Effects of base sequence on the loop folding in DNA hairpins. Biochemistry (1989) 2.05
The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis. J Biol Chem (2005) 1.84
The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps. DNA Repair (Amst) (2005) 1.81
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps. EMBO J (2007) 1.80
Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol (2004) 1.63
Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence. Nucleic Acids Res (2007) 1.56
Functional and biochemical dissection of the structure-specific nuclease ARTEMIS. EMBO J (2004) 1.54
Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase. Nucleic Acids Res (2008) 1.36
Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease. J Biol Chem (2006) 1.31
DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs. J Biol Chem (2006) 1.28
A biochemically defined system for coding joint formation in V(D)J recombination. Mol Cell (2008) 1.13
Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability. J Exp Med (2009) 1.07
Conformational feasibility of a hairpin with two purines in the loop. 5'-d-GGTACIAGTACC-3'. Biochemistry (1991) 0.94
Extent to which hairpin opening by the Artemis:DNA-PKcs complex can contribute to junctional diversity in V(D)J recombination. Nucleic Acids Res (2007) 0.93
Hairpin formation in the self-complementary dodecamer d-GGTACGCGTACC and derivatives containing GA and IA mispairs. Biochemistry (1991) 0.87
InsPecT: identification of posttranslationally modified peptides from tandem mass spectra. Anal Chem (2005) 6.65
Mechanism and regulation of human non-homologous DNA end-joining. Nat Rev Mol Cell Biol (2003) 6.49
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell (2002) 6.34
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat Immunol (2003) 4.81
Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes. Immunity (2010) 3.59
Bidirectional gene organization: a common architectural feature of the human genome. Cell (2002) 3.47
Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell (2008) 3.31
A biochemically defined system for mammalian nonhomologous DNA end joining. Mol Cell (2004) 3.01
A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex. Nature (2004) 2.92
Identification of post-translational modifications by blind search of mass spectra. Nat Biotechnol (2005) 2.84
The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. Proc Natl Acad Sci U S A (2002) 2.82
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. Cancer Cell (2009) 2.42
H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations. Mol Cell (2009) 2.40
Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr Biol (2002) 2.27
DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine. J Biol Chem (2003) 2.16
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16. Mol Cell (2008) 1.99
Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications. Mol Ther (2010) 1.95
The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination. DNA Repair (Amst) (2004) 1.93
Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a single-center cohort of 55 patients. Pediatrics (2003) 1.91
Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells. Proc Natl Acad Sci U S A (2009) 1.91
The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis. J Biol Chem (2005) 1.84
Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene and VHL-haplotype analysis in patients with presumable congenital erythrocytosis. Haematologica (2005) 1.83
The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps. DNA Repair (Amst) (2005) 1.81
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps. EMBO J (2007) 1.80
Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Mol Cell Biol (2003) 1.76
Acid rain in China. Environ Sci Technol (2006) 1.75
An immunodeficiency disease with RAG mutations and granulomas. N Engl J Med (2008) 1.71
SCID patients with ARTEMIS vs RAG deficiencies following HCT: increased risk of late toxicity in ARTEMIS-deficient SCID. Blood (2013) 1.68
Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity. J Biol Chem (2007) 1.65
The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J Biol Chem (2005) 1.64
Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease. Am J Hum Genet (2011) 1.63
Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol (2004) 1.63
hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro. Mol Cell Biol (2002) 1.58
Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence. Nucleic Acids Res (2007) 1.56
Functional and biochemical dissection of the structure-specific nuclease ARTEMIS. EMBO J (2004) 1.54
A variant of SCID with specific immune responses and predominance of gamma delta T cells. J Clin Invest (2005) 1.54
Mechanism of R-loop formation at immunoglobulin class switch sequences. Mol Cell Biol (2007) 1.54
Impact of DNA ligase IV on the fidelity of end joining in human cells. Nucleic Acids Res (2003) 1.52
Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism. DNA Repair (Amst) (2003) 1.51
Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region. Mol Cell Biol (2007) 1.48
Omenn syndrome due to ARTEMIS mutations. Blood (2005) 1.47
Mismatch repair participates in error-free processing of DNA interstrand crosslinks in human cells. EMBO Rep (2005) 1.46
Severe combined immunodeficiency and microcephaly in siblings with hypomorphic mutations in DNA ligase IV. Eur J Immunol (2006) 1.45
G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter. Mol Cell Biol (2009) 1.43
Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site. Mol Cell Biol (2010) 1.43
Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type II. Blood (2006) 1.42
The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants. DNA Repair (Amst) (2002) 1.41
Results of intracoronary stem cell therapy after acute myocardial infarction. Am J Cardiol (2010) 1.40
Clinical and immunological manifestations of patients with atypical severe combined immunodeficiency. Clin Immunol (2011) 1.38
Mechanisms of chromosomal rearrangement in the human genome. BMC Genomics (2010) 1.37
Deficiency of innate and acquired immunity caused by an IKBKB mutation. N Engl J Med (2013) 1.37
ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis. Proc Natl Acad Sci U S A (2011) 1.35
Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locus. J Gene Med (2006) 1.35
Downstream boundary of chromosomal R-loops at murine switch regions: implications for the mechanism of class switch recombination. Proc Natl Acad Sci U S A (2006) 1.35
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nat Genet (2008) 1.34
Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency. J Immunol (2011) 1.32
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. EMBO J (2010) 1.32
Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops. Mol Cell Biol (2005) 1.32
A severe form of human combined immunodeficiency due to mutations in DNA ligase IV. J Immunol (2006) 1.31
High-resolution HLA matching in hematopoietic stem cell transplantation: a retrospective collaborative analysis. Blood (2013) 1.30
Signaling role of intracellular iron in NF-kappaB activation. J Biol Chem (2003) 1.30
Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma. Nucleic Acids Res (2010) 1.30
Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia. J Biol Chem (2002) 1.29
Breaking chemoresistance and radioresistance with [213Bi]anti-CD45 antibodies in leukemia cells. Cancer Res (2007) 1.29
Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model. Cell Cycle (2005) 1.28
DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs. J Biol Chem (2006) 1.28
Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro. Mol Cell Biol (2005) 1.27
Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation. J Biol Chem (2005) 1.27
Generation and characterization of endonuclease G null mice. Mol Cell Biol (2005) 1.25
Genetic interactions between BLM and DNA ligase IV in human cells. J Biol Chem (2004) 1.25
Turning anti-ageing genes against cancer. Nat Rev Mol Cell Biol (2008) 1.23
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc Natl Acad Sci U S A (2012) 1.18
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation. Cell Host Microbe (2012) 1.16
Targeted chromosomal gene modification in human cells by single-stranded oligodeoxynucleotides in the presence of a DNA double-strand break. Mol Ther (2006) 1.16
A novel single point mutation of the LYST gene in two siblings with different phenotypic features of Chediak Higashi syndrome. Pediatr Blood Cancer (2011) 1.16
Congenital dyserythropoietic anemia type I (CDA I): molecular genetics, clinical appearance, and prognosis based on long-term observation. Blood (2005) 1.16
Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases. Haematologica (2010) 1.15
DNA structures at chromosomal translocation sites. Bioessays (2006) 1.14
A biochemically defined system for coding joint formation in V(D)J recombination. Mol Cell (2008) 1.13
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. Nat Nanotechnol (2013) 1.12
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome. Blood (2011) 1.12
Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma. J Biol Chem (2008) 1.12