Published in Stem Cells on April 01, 2010
Targeting autophagy during cancer therapy to improve clinical outcomes. Pharmacol Ther (2011) 1.55
Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells. Environ Health Perspect (2012) 1.53
Salinomycin as a drug for targeting human cancer stem cells. J Biomed Biotechnol (2012) 1.50
Strategies for optimizing the response of cancer and normal tissues to radiation. Nat Rev Drug Discov (2013) 1.25
Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells. Cell Death Differ (2013) 1.12
Ionizing radiation, ion transports, and radioresistance of cancer cells. Front Physiol (2013) 1.09
Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures. PLoS One (2013) 1.05
Are cancer stem cells radioresistant? Future Oncol (2010) 1.01
Novel PI3K and mTOR Inhibitor NVP-BEZ235 Radiosensitizes Breast Cancer Cell Lines under Normoxic and Hypoxic Conditions. Breast Cancer (Auckl) (2014) 0.98
Cancer stem cells, tumor dormancy, and metastasis. Front Endocrinol (Lausanne) (2012) 0.96
Multispecies model of cell lineages and feedback control in solid tumors. J Theor Biol (2012) 0.95
Cancer stem cells and chemoresistance: The smartest survives the raid. Pharmacol Ther (2016) 0.93
MicroRNA in radiotherapy: miRage or miRador? Br J Cancer (2015) 0.89
SPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131I. PLoS One (2012) 0.89
Isolation and applications of prostate side population cells based on dye cycle violet efflux. Curr Protoc Toxicol (2011) 0.89
Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Br J Cancer (2014) 0.89
Non-invasive in vivo imaging of tumor-associated CD133/prominin. PLoS One (2010) 0.88
IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation. Radiat Oncol (2015) 0.86
Thyroid tumor-initiating cells: increasing evidence and opportunities for anticancer therapy (review). Oncol Rep (2014) 0.86
Yes-associated protein (YAP) modulates oncogenic features and radiation sensitivity in endometrial cancer. PLoS One (2014) 0.85
Release of monocyte migration signals by breast cancer cell lines after ablative and fractionated γ-irradiation. Radiat Oncol (2014) 0.85
TRA-1-60(+), SSEA-4(+), POU5F1(+), SOX2(+), NANOG(+) Clones of Pluripotent Stem Cells in the Embryonal Carcinomas of the Testes. J Stem Cell Res Ther (2013) 0.83
Impact of Autophagy on Chemotherapy and Radiotherapy Mediated Tumor Cytotoxicity: "To Live or not to Live". Front Oncol (2011) 0.83
Targeting Notch to overcome radiation resistance. Oncotarget (2016) 0.82
Therapeutic and radiosensitizing effects of armillaridin on human esophageal cancer cells. Evid Based Complement Alternat Med (2013) 0.82
Tumor Cells Surviving Exposure to Proton or Photon Radiation Share a Common Immunogenic Modulation Signature, Rendering Them More Sensitive to T Cell-Mediated Killing. Int J Radiat Oncol Biol Phys (2016) 0.82
A proposed quantitative index for assessing the potential contribution of reprogramming to cancer stem cell kinetics. Stem Cells Int (2014) 0.82
Profiling global kinome signatures of the radioresistant MCF-7/C6 breast cancer cells using MRM-based targeted proteomics. J Proteome Res (2014) 0.82
Regulation of miRNAs affects radiobiological response of lung cancer stem cells. Biomed Res Int (2015) 0.82
Dynamics between cancer cell subpopulations reveals a model coordinating with both hierarchical and stochastic concepts. PLoS One (2014) 0.81
Pulmonary adenocarcinoma: implications of the recent advances in molecular biology, treatment and the IASLC/ATS/ERS classification. J Thorac Dis (2014) 0.81
Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling. Cancer Inform (2011) 0.81
Mathematical optimization of the combination of radiation and differentiation therapies for cancer. Front Oncol (2013) 0.80
Knockdown of the T-box transcription factor Brachyury increases sensitivity of adenoid cystic carcinoma cells to chemotherapy and radiation in vitro: implications for a new therapeutic principle. Int J Oncol (2014) 0.80
MET inhibition overcomes radiation resistance of glioblastoma stem-like cells. EMBO Mol Med (2016) 0.79
Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism. Stem Cell Res Ther (2015) 0.78
Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling. Oncotarget (2016) 0.78
Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment. Front Pharmacol (2016) 0.78
Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy. Oncotarget (2016) 0.77
Targetable T-type calcium channels drive glioblastoma. Cancer Res (2017) 0.77
Tumor Induction in Mice After Localized Single- or Fractionated-Dose Irradiation: Differences in Tumor Histotype and Genetic Susceptibility Based on Dose Scheduling. Int J Radiat Oncol Biol Phys (2015) 0.77
The insights of Let-7 miRNAs in oncogenesis and stem cell potency. J Cell Mol Med (2016) 0.77
Invasive oral cancer stem cells display resistance to ionising radiation. Oncotarget (2015) 0.77
Genotoxic Damage to Glioblastoma Cells Treated with 6 MV X-Radiation in The Presence or Absence of Methoxy Estradiol, IUDR or Topotecan. Cell J (2015) 0.77
Effects of Charged Particles on Human Tumor Cells. Front Oncol (2016) 0.77
Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway. Oncol Lett (2016) 0.77
Abnormal expression of the Notch and Wnt/β-catenin signaling pathways in stem-like ALDH(hi)CD44(+) cells correlates highly with Ki-67 expression in breast cancer. Oncol Lett (2015) 0.77
Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells. Oncotarget (2015) 0.76
Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44(+)/CD24(-/low) Stem Cell Phenotype. Front Oncol (2016) 0.76
Enhancement of tumor initiation and expression of KCNMA1, MORF4L2 and ASPM genes in the adenocarcinoma of lung xenograft after vorinostat treatment. Oncotarget (2015) 0.76
Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity. BMC Cancer (2016) 0.76
Optimization of radiation dosing schedules for proneural glioblastoma. J Math Biol (2015) 0.76
K(+) channel signaling in irradiated tumor cells. Eur Biophys J (2016) 0.76
The crossroads between cancer stem cells and aging. BMC Cancer (2015) 0.76
Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside. Oncotarget (2016) 0.76
The reoxygenation of hypoxia and the reduction of glucose metabolism in head and neck cancer by fractionated radiotherapy with intensity-modulated radiation therapy. Eur J Nucl Med Mol Imaging (2016) 0.76
Increased activity of CHK enhances the radioresistance of MCF-7 breast cancer stem cells. Oncol Lett (2015) 0.75
Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma. J Ther Ultrasound (2016) 0.75
Crosstalk Between Cancer Associated Fibroblasts and Cancer Cells in the Tumor Microenvironment After Radiotherapy. EBioMedicine (2017) 0.75
Opportunities for Radiosensitization in the Stereotactic Body Radiation Therapy (SBRT) Era. Cancer J (2016) 0.75
Inhibition of mTOR sensitizes breast cancer stem cells to radiation-induced repression of self-renewal through the regulation of MnSOD and Akt. Int J Mol Med (2015) 0.75
Side population cells from long-term passage non-small cell lung cancer cells display loss of cancer stem cell-like properties and chemoradioresistance. Oncol Lett (2016) 0.75
Targeting stem cells by radiation: From the biological angle to clinical aspects. World J Stem Cells (2016) 0.75
TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo. Oncol Lett (2016) 0.75
Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1. Dev Biol (2015) 0.75
Role of ATP as a Key Signaling Molecule Mediating Radiation-Induced Biological Effects. Dose Response (2017) 0.75
Tumor-initiating cells contribute to radiation resistance in primary human renal clear cell carcinomas by activating the DNA damage checkpoint response. Oncol Lett (2017) 0.75
Cycling CD34 expression in subpopulations of head and neck squamous cell carcinoma cell lines is involved in radioresistance and change in cytokeratin expression profile. Clin Exp Med (2016) 0.75
Epigenetic Mechanisms of Tamoxifen Resistance in Luminal Breast Cancer. Diseases (2017) 0.75
Distinct Levels of Radioresistance in Lgr5(+) Colonic Epithelial Stem Cells versus Lgr5(+) Small Intestinal Stem Cells. Cancer Res (2017) 0.75
The changing paradigm of tumour response to irradiation. Br J Radiol (2016) 0.75
Evaluating biomarkers to model cancer risk post cosmic ray exposure. Life Sci Space Res (Amst) (2016) 0.75
Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17
Stem cells, cancer, and cancer stem cells. Nature (2001) 50.27
Identification of human brain tumour initiating cells. Nature (2004) 38.87
Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature (2007) 29.32
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature (2006) 27.91
Identification of a cancer stem cell in human brain tumors. Cancer Res (2003) 24.02
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature (1994) 21.59
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab (2008) 18.87
Identification of pancreatic cancer stem cells. Cancer Res (2007) 18.36
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res (2006) 17.42
Efficient tumour formation by single human melanoma cells. Nature (2008) 16.35
Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res (2005) 13.89
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell (2004) 12.67
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell (2007) 12.52
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A (2007) 11.94
Crypt stem cells as the cells-of-origin of intestinal cancer. Nature (2008) 11.66
A perivascular niche for brain tumor stem cells. Cancer Cell (2007) 11.55
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell (2008) 11.53
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature (2005) 11.49
Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet (2003) 11.47
Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A (2003) 10.56
The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer (1955) 10.49
Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature (2009) 10.31
The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst (2006) 10.06
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell (2009) 8.33
Identification of cells initiating human melanomas. Nature (2008) 8.28
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res (2009) 7.98
A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res (2005) 7.86
Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science (2003) 7.86
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res (2008) 7.65
The impact of O2 availability on human cancer. Nat Rev Cancer (2008) 6.84
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res (1996) 6.62
Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature (2008) 5.59
Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol (2006) 5.56
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res (1996) 4.98
WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A (2007) 4.97
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys (1997) 4.55
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood (2007) 4.49
Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability. Nat Rev Cancer (2008) 4.43
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. Radiother Oncol (2005) 3.86
Imaging hematopoietic precursor division in real time. Cell Stem Cell (2007) 3.62
Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer (2008) 3.56
DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell (2009) 3.48
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer (2008) 3.46
Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia. J Clin Oncol (2007) 3.12
Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ (2006) 3.12
Rational targeting of Notch signaling in cancer. Oncogene (2008) 3.02
Role of cell cycle in mediating sensitivity to radiotherapy. Int J Radiat Oncol Biol Phys (2004) 3.00
Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer. J Clin Oncol (2002) 2.82
Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J Cell Biochem (2007) 2.67
Mammary stem cells and breast cancer--role of Notch signalling. Stem Cell Rev (2007) 2.62
Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol (1996) 2.44
In vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst (2009) 2.39
Studies of the dissemination and quantitative transplantation of a lymphocytic leukaemia of CBA mice. Br J Cancer (1958) 2.34
Identifying cancer stem cells in solid tumors: case not proven. Cancer Res (2006) 2.28
Tumour stem cells: the biological concept and its application in cancer treatment. Radiother Oncol (1994) 2.16
Establishment of a normal hematopoietic and leukemia stem cell hierarchy. Cold Spring Harb Symp Quant Biol (2008) 2.13
Cancer stem cells and radiotherapy: new insights into tumor radioresistance. J Natl Cancer Inst (2006) 2.10
Transforming growth factor-beta activation in irradiated murine mammary gland. J Clin Invest (1994) 2.01
The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells. Int J Cancer (2009) 1.98
WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics. Cell Res (2009) 1.89
Cancer stem cell-directed therapies: recent data from the laboratory and clinic. Mol Ther (2008) 1.83
The TGF-beta paradox in human cancer: an update. Future Oncol (2009) 1.79
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. EMBO J (2004) 1.78
Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer. Cancer Res (2005) 1.76
CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines. Clin Cancer Res (2009) 1.72
Local control of carcinoma of the tonsil by radiation therapy: an analysis of patterns of fractionation in nine institutions. Int J Radiat Oncol Biol Phys (1995) 1.70
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res (2008) 1.70
Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation. FASEB J (1997) 1.65
CD133 is a marker of bioenergetic stress in human glioma. PLoS One (2008) 1.63
Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia. Int J Radiat Oncol Biol Phys (2006) 1.62
Notch activates cell cycle reentry and progression in quiescent cardiomyocytes. J Cell Biol (2008) 1.59
HER-2, notch, and breast cancer stem cells: targeting an axis of evil. Clin Cancer Res (2009) 1.59
Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms. Oncogene (2004) 1.54
Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO J (2008) 1.52
"Destemming" cancer stem cells. J Natl Cancer Inst (2007) 1.51
CD133 (Prominin) negative human neural stem cells are clonogenic and tripotent. PLoS One (2009) 1.50
Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation. Methods Cell Biol (2004) 1.49
Nonproliferating CML CD34+ progenitors are resistant to apoptosis induced by a wide range of proapoptotic stimuli. Leukemia (2005) 1.49
Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor. PLoS One (2008) 1.37
Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix. Br J Cancer (1998) 1.35
Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines. Clin Cancer Res (2008) 1.35
Time factor in postoperative radiotherapy: a multivariate locoregional control analysis in 868 patients. Int J Radiat Oncol Biol Phys (2003) 1.32
Effects of recombinant erythropoietin on breast cancer-initiating cells. Neoplasia (2007) 1.29
Rad51 protein controls Rad52-mediated DNA annealing. J Biol Chem (2008) 1.23
Phosphatases, DNA damage checkpoints and checkpoint deactivation. Cell Cycle (2007) 1.21
Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression. Biochem Biophys Res Commun (2009) 1.20
Separating stem cells by flow cytometry: reducing variability for solid tissues. Cell Stem Cell (2009) 1.20
Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors. Clin Cancer Res (2009) 1.19
A garden of Notch-ly delights. Development (2006) 1.19
Ionizing radiation shifts the PAI-1/ID-1 balance and activates notch signaling in endothelial cells. Int J Radiat Oncol Biol Phys (2009) 1.15
Limits of CD133 as a marker of glioma self-renewing cells. Int J Cancer (2009) 1.14
Comparative analysis of DNA repair in stem and nonstem glioma cell cultures. Mol Cancer Res (2009) 1.13
The role of glutathione in radiation and drug induced cytotoxicity. Br J Cancer Suppl (1987) 1.12
Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas. Stem Cells (2008) 1.11
Survivin antisense oligonucleotides effectively radiosensitize colorectal cancer cells in both tissue culture and murine xenograft models. Int J Radiat Oncol Biol Phys (2008) 1.08
Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300. Cancer Sci (2005) 1.05
Study of tumor blood perfusion and its variation due to vascular normalization by anti-angiogenic therapy based on 3D angiogenic microvasculature. J Biomech (2009) 1.03
Radiation response of cancer stem-like cells from established human cell lines after sorting for surface markers. Int J Radiat Oncol Biol Phys (2009) 1.02
Erythropoietin induces cancer cell resistance to ionizing radiation and to cisplatin. Mol Cancer Ther (2004) 1.02
The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst (2006) 10.06
Effects of radiation on normal tissue: consequences and mechanisms. Lancet Oncol (2003) 3.70
Animal models for medical countermeasures to radiation exposure. Radiat Res (2010) 2.83
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
Combining radiotherapy and immunotherapy: a revived partnership. Int J Radiat Oncol Biol Phys (2005) 2.29
Radiation-induced reprogramming of breast cancer cells. Stem Cells (2012) 1.83
Determinant spreading associated with clinical response in dendritic cell-based immunotherapy for malignant melanoma. Clin Cancer Res (2003) 1.83
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer. J Clin Oncol (2009) 1.82
The biological effectiveness of antiproton irradiation. Radiother Oncol (2006) 1.66
T-cell responses to survivin in cancer patients undergoing radiation therapy. Clin Cancer Res (2008) 1.61
Maximizing tumor immunity with fractionated radiation. Int J Radiat Oncol Biol Phys (2011) 1.60
Survival and self-renewing capacity of breast cancer initiating cells during fractionated radiation treatment. Breast Cancer Res (2010) 1.59
The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas. Clin Cancer Res (2006) 1.51
A phase I/II trial testing immunization of hepatocellular carcinoma patients with dendritic cells pulsed with four alpha-fetoprotein peptides. Clin Cancer Res (2006) 1.48
Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells. Cancer Res (2006) 1.45
Ionizing radiation affects human MART-1 melanoma antigen processing and presentation by dendritic cells. J Immunol (2004) 1.44
National Institutes of Health funding in radiation oncology: a snapshot. Int J Radiat Oncol Biol Phys (2013) 1.42
Role of dendritic cell phenotype, determinant spreading, and negative costimulatory blockade in dendritic cell-based melanoma immunotherapy. J Immunother (2004) 1.40
Molecular mechanisms of late normal tissue injury. Semin Radiat Oncol (2007) 1.40
Radiation enhances regulatory T cell representation. Int J Radiat Oncol Biol Phys (2010) 1.39
Ionizing radiation activates the Nrf2 antioxidant response. Cancer Res (2010) 1.35
The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells. Cancer Res (2002) 1.31
Effects of recombinant erythropoietin on breast cancer-initiating cells. Neoplasia (2007) 1.29
Cytokines in radiobiological responses: a review. Radiat Res (2012) 1.29
Macrophages from irradiated tumors express higher levels of iNOS, arginase-I and COX-2, and promote tumor growth. Int J Radiat Oncol Biol Phys (2007) 1.28
After the bomb drops: a new look at radiation-induced multiple organ dysfunction syndrome (MODS). Int J Radiat Biol (2011) 1.24
T-cell responses to HLA-A*0201 immunodominant peptides derived from alpha-fetoprotein in patients with hepatocellular cancer. Clin Cancer Res (2003) 1.24
Links between innate immunity and normal tissue radiobiology. Radiat Res (2010) 1.19
Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors. Clin Cancer Res (2009) 1.19
Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers. Int J Radiat Oncol Biol Phys (2006) 1.12
Compartmental responses after thoracic irradiation of mice: strain differences. Int J Radiat Oncol Biol Phys (2005) 1.11
Radiation responses of cancer stem cells. J Cell Biochem (2009) 1.08
Anthracyclines, proteasome activity and multi-drug-resistance. BMC Cancer (2005) 1.08
The confluence of stereotactic ablative radiotherapy and tumor immunology. Clin Dev Immunol (2011) 1.05
Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis. Arthritis Res Ther (2006) 1.05
Human dendritic cell maturation by adenovirus transduction enhances tumor antigen-specific T-cell responses. J Immunother (2004) 1.03
Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus. Antivir Ther (2005) 1.02
High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones. Clin Cancer Res (2009) 1.02
N-acetyl-L-cysteine inhibits 26S proteasome function: implications for effects on NF-kappaB activation. Free Radic Biol Med (2002) 1.01
Bronchoalveolar lavage and interstitial cells have different roles in radiation-induced lung injury. Int J Radiat Biol (2003) 1.00
SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. Cell Signal (2008) 0.98
Regulatory T cells in radiotherapeutic responses. Front Oncol (2012) 0.98
The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism. BMC Cancer (2005) 0.97
Preparing for the future of radiation oncology. J Am Coll Radiol (2007) 0.97
Spinal cord tolerance to single-fraction partial-volume irradiation: a swine model. Int J Radiat Oncol Biol Phys (2010) 0.96
Hyperthermia-induced proteasome inhibition and loss of androgen receptor expression in human prostate cancer cells. Cancer Res (2005) 0.96
Functional phenotype of macrophages depends on assay procedures. Int Immunol (2007) 0.95
The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells. Stem Cells (2014) 0.95
Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade). J Immunol (2006) 0.95
Lymphatic fistulas: obliteration by low-dose radiotherapy. Strahlenther Onkol (2005) 0.94
Radioprotective effects of Bmi-1 involve epigenetic silencing of oxidase genes and enhanced DNA repair in normal human keratinocytes. J Invest Dermatol (2011) 0.93
Induction of radioprotective peroxiredoxin-I by ionizing irradiation. J Neurosci Res (2002) 0.92
Tumor cells with low proteasome subunit expression predict overall survival in head and neck cancer patients. BMC Cancer (2014) 0.91
Radiation-induced Notch signaling in breast cancer stem cells. Int J Radiat Oncol Biol Phys (2013) 0.91
Protection against radiation-induced bone marrow and intestinal injuries by Cordyceps sinensis, a Chinese herbal medicine. Radiat Res (2006) 0.91
The effects of tea extracts on proinflammatory signaling. BMC Med (2006) 0.91
HDJ-2 as a target for radiosensitization of glioblastoma multiforme cells by the farnesyltransferase inhibitor R115777 and the role of the p53/p21 pathway. Cancer Res (2006) 0.91
Enhanced tumor responses to dendritic cells in the absence of CD8-positive cells. J Immunol (2004) 0.91
High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol (2011) 0.90
Immunomagnetic diffractometry for detection of diagnostic serum markers. J Am Chem Soc (2007) 0.90
Spinal cord tolerance to reirradiation with single-fraction radiosurgery: a swine model. Int J Radiat Oncol Biol Phys (2011) 0.89
Differential Effects of the Proteasome Inhibitor NPI-0052 against Glioma Cells. Transl Oncol (2010) 0.88
Epidermal growth factor receptor vIII expression in U87 glioblastoma cells alters their proteasome composition, function, and response to irradiation. Mol Cancer Res (2008) 0.87
5-aminoimidazole-4-carboxamide riboside enhances effect of ionizing radiation in PC3 prostate cancer cells. Int J Radiat Oncol Biol Phys (2011) 0.87
T lymphocytes and normal tissue responses to radiation. Front Oncol (2012) 0.86
Modification of the tumor microenvironment to enhance immunity. Front Biosci (2007) 0.86
Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies. Head Neck (2005) 0.86
Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells. Cancer Gene Ther (2005) 0.86
Proteasome structures affected by ionizing radiation. Mol Cancer Res (2005) 0.86
Fibrin microbeads loaded with mesenchymal cells support their long-term survival while sealed at room temperature. Tissue Eng Part C Methods (2011) 0.86
Education and training for radiation scientists: radiation research program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003. Radiat Res (2003) 0.86
Folate-linked drugs for the treatment of cancer and inflammatory diseases. Subcell Biochem (2012) 0.85
Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models. J Immunother (2013) 0.84
Marrow-derived stromal cell delivery on fibrin microbeads can correct radiation-induced wound-healing deficits. J Invest Dermatol (2012) 0.84
Integration of epidermal growth factor receptor inhibitors with preoperative chemoradiation. Clin Cancer Res (2010) 0.84
Local irradiation of murine melanoma affects the development of tumour-specific immunity. Immunology (2009) 0.83
Modifying normal tissue damage postirradiation. Report of a workshop sponsored by the Radiation Research Program, National Cancer Institute, Bethesda, Maryland, September 6-8, 2000. Radiat Res (2002) 0.83
Counteracting tumor radioresistance by targeting DNA repair. Mol Cancer Ther (2005) 0.83
Adenoviral interleukin-3 gene-radiation therapy for prostate cancer in mouse model. Int J Radiat Oncol Biol Phys (2004) 0.83
Targeted cancer stem cell therapies start with proper identification of the target. Mol Cancer Res (2010) 0.82
Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. Prostate (2003) 0.82
Spinal cord tolerance to single-session uniform irradiation in pigs: implications for a dose-volume effect. Radiother Oncol (2012) 0.82
The proteasome inhibitor MG-132 protects hypoxic SiHa cervical carcinoma cells after cyclic hypoxia/reoxygenation from ionizing radiation. Neoplasia (2006) 0.81
Molecular and clinico-pathological markers in rectal cancer: a tissue micro-array study. Int J Colorectal Dis (2008) 0.81
Immunosuppressive effects of interleukin-12 coexpression in melanoma antigen gene-modified dendritic cell vaccines. Cancer Gene Ther (2002) 0.81
Cordyceps sinensis health supplement enhances recovery from taxol-induced leukopenia. Exp Biol Med (Maywood) (2008) 0.81
Modifying radiation damage. Curr Drug Targets (2010) 0.81
Characterization of the stem cell niche and its importance in radiobiological response. Semin Radiat Oncol (2013) 0.80
Insulin-like growth factor-type 1 receptor inhibitor NVP-AEW541 enhances radiosensitivity of PTEN wild-type but not PTEN-deficient human prostate cancer cells. Int J Radiat Oncol Biol Phys (2011) 0.80
Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer. Radiother Oncol (2009) 0.80
Imaging of radiation effects on cellular 26S proteasome function in situ. Int J Radiat Biol (2009) 0.79
Radiation biology in the context of changing patterns of radiotherapy. Radiat Res (2014) 0.79
Folate receptor-β in activated macrophages: ligand binding and receptor recycling kinetics. Mol Pharm (2014) 0.78
A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model. Arch Otolaryngol Head Neck Surg (2012) 0.77
Immune rejection in a humanized model of murine prostate cancer. Anticancer Res (2010) 0.75
Broad antitumor protection by dendritic cells administered to CD8alpha knock out mice. Cancer Immunol Immunother (2005) 0.75