Published in J Biol Chem on February 12, 2010
Structure of the ATP synthase catalytic complex (F(1)) from Escherichia coli in an autoinhibited conformation. Nat Struct Mol Biol (2011) 1.72
Chemomechanical coupling of human mitochondrial F1-ATPase motor. Nat Chem Biol (2014) 1.01
F1-ATPase of Escherichia coli: the ε- inhibited state forms after ATP hydrolysis, is distinct from the ADP-inhibited state, and responds dynamically to catalytic site ligands. J Biol Chem (2013) 0.94
Variations of subunit {varepsilon} of the Mycobacterium tuberculosis F1Fo ATP synthase and a novel model for mechanism of action of the tuberculosis drug TMC207. Antimicrob Agents Chemother (2012) 0.92
Efficient ATP synthesis by thermophilic Bacillus FoF1-ATP synthase. FEBS J (2011) 0.88
Characterization of the relationship between ADP- and epsilon-induced inhibition in cyanobacterial F1-ATPase. J Biol Chem (2011) 0.83
Modulation of nucleotide specificity of thermophilic F(o)F(1)-ATP Synthase by epsilon-subunit. J Biol Chem (2011) 0.80
Spotlighting motors and controls of single FoF1-ATP synthase. Biochem Soc Trans (2013) 0.80
A conformational change of the γ subunit indirectly regulates the activity of cyanobacterial F1-ATPase. J Biol Chem (2012) 0.79
Simple mechanism whereby the F1-ATPase motor rotates with near-perfect chemomechanical energy conversion. Proc Natl Acad Sci U S A (2015) 0.78
The regulatory switch of F1-ATPase studied by single-molecule FRET in the ABEL Trap. Proc SPIE Int Soc Opt Eng (2014) 0.78
Direct observation of the rotation of F1-ATPase. Nature (1997) 9.57
Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase. Nature (2001) 5.63
The binding change mechanism for ATP synthase--some probabilities and possibilities. Biochim Biophys Acta (1993) 4.88
ATP synthase--a marvellous rotary engine of the cell. Nat Rev Mol Cell Biol (2001) 4.81
Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation. Cell (2007) 4.09
Proton-powered subunit rotation in single membrane-bound F0F1-ATP synthase. Nat Struct Mol Biol (2004) 2.50
Rotation of subunits during catalysis by Escherichia coli F1-ATPase. Proc Natl Acad Sci U S A (1995) 2.39
Highly coupled ATP synthesis by F1-ATPase single molecules. Nature (2005) 2.32
Pause and rotation of F(1)-ATPase during catalysis. Proc Natl Acad Sci U S A (2001) 2.07
Essentials for ATP synthesis by F1F0 ATP synthases. Annu Rev Biochem (2009) 1.89
Powering the flagellar motor of Escherichia coli with an external voltage source. Nature (1995) 1.78
The speed of the flagellar rotary motor of Escherichia coli varies linearly with protonmotive force. Proc Natl Acad Sci U S A (2003) 1.59
The rotary mechanism of the ATP synthase. Arch Biochem Biophys (2008) 1.58
Structure of the gamma-epsilon complex of ATP synthase. Nat Struct Biol (2000) 1.56
F1-ATPase rotates by an asymmetric, sequential mechanism using all three catalytic subunits. Nat Struct Mol Biol (2007) 1.53
ATP-driven stepwise rotation of FoF1-ATP synthase. Proc Natl Acad Sci U S A (2005) 1.43
Activation of pausing F1 motor by external force. Proc Natl Acad Sci U S A (2005) 1.41
F0F1-ATPase/synthase is geared to the synthesis mode by conformational rearrangement of epsilon subunit in response to proton motive force and ADP/ATP balance. J Biol Chem (2003) 1.36
Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. J Biol Chem (2006) 1.32
Crystal structure of the epsilon subunit of the proton-translocating ATP synthase from Escherichia coli. Structure (1997) 1.30
H+/ATP ratio of proton transport-coupled ATP synthesis and hydrolysis catalysed by CF0F1-liposomes. EMBO J (2003) 1.30
Structures of the thermophilic F1-ATPase epsilon subunit suggesting ATP-regulated arm motion of its C-terminal domain in F1. Proc Natl Acad Sci U S A (2007) 1.30
Microsecond time scale rotation measurements of single F1-ATPase molecules. Biochemistry (2006) 1.27
Direct observation of the rotation of epsilon subunit in F1-ATPase. J Biol Chem (1998) 1.26
The H+/ATP coupling ratio of the ATP synthase from thiol-modulated chloroplasts and two cyanobacterial strains is four. FEBS Lett (1996) 1.23
Epsilon subunit, an endogenous inhibitor of bacterial F(1)-ATPase, also inhibits F(0)F(1)-ATPase. J Biol Chem (1999) 1.23
Mechanism of inhibition by C-terminal alpha-helices of the epsilon subunit of Escherichia coli FoF1-ATP synthase. J Biol Chem (2009) 1.19
Purine but not pyrimidine nucleotides support rotation of F(1)-ATPase. J Biol Chem (2001) 1.15
Solution structure of the epsilon subunit of the F1-ATPase from Escherichia coli and interactions of this subunit with beta subunits in the complex. J Biol Chem (1998) 1.11
Slow binding of ATP to noncatalytic nucleotide binding sites which accelerates catalysis is responsible for apparent negative cooperativity exhibited by the bovine mitochondrial F1-ATPase. J Biol Chem (1993) 1.10
Stochastic high-speed rotation of Escherichia coli ATP synthase F1 sector: the epsilon subunit-sensitive rotation. J Biol Chem (2005) 1.10
Isolated epsilon subunit of thermophilic F1-ATPase binds ATP. J Biol Chem (2003) 1.09
Real-time monitoring of conformational dynamics of the epsilon subunit in F1-ATPase. J Biol Chem (2005) 1.07
F1-ATPase: a highly efficient rotary ATP machine. Essays Biochem (2000) 1.02
Regulatory mechanisms of proton-translocating F(O)F (1)-ATP synthase. Results Probl Cell Differ (2008) 1.01
The activity of the ATP synthase from Escherichia coli is regulated by the transmembrane proton motive force. J Biol Chem (2000) 1.01
The regulator of the F1 motor: inhibition of rotation of cyanobacterial F1-ATPase by the epsilon subunit. EMBO J (2006) 1.00
The role of the epsilon subunit in the Escherichia coli ATP synthase. The C-terminal domain is required for efficient energy coupling. J Biol Chem (2005) 0.99
Role of the epsilon subunit of thermophilic F1-ATPase as a sensor for ATP. J Biol Chem (2007) 0.98
Thermophilic F1-ATPase is activated without dissociation of an endogenous inhibitor, epsilon subunit. J Biol Chem (1997) 0.97
Effect of the epsilon-subunit on nucleotide binding to Escherichia coli F1-ATPase catalytic sites. J Biol Chem (1999) 0.97
The role of the betaDELSEED motif of F1-ATPase: propagation of the inhibitory effect of the epsilon subunit. J Biol Chem (2001) 0.97
Rotation of the epsilon subunit during catalysis by Escherichia coli FOF1-ATP synthase. J Biol Chem (1998) 0.94
Rotor/Stator interactions of the epsilon subunit in Escherichia coli ATP synthase and implications for enzyme regulation. J Biol Chem (2004) 0.94
Cross-linking of two beta subunits in the closed conformation in F1-ATPase. J Biol Chem (1999) 0.94
Movement of the helical domain of the epsilon subunit is required for the activation of thermophilic F1-ATPase. J Biol Chem (2000) 0.90
Probing conformations of the beta subunit of F0F1-ATP synthase in catalysis. Biochem Biophys Res Commun (2006) 0.90
Effect of epsilon subunit on the rotation of thermophilic Bacillus F1-ATPase. FEBS Lett (2009) 0.88
The critical electric potential difference for photophosphorylation. Its relation to the chemiosmotic hypothesis and to the triggering requirements of the ATPase system. Eur J Biochem (1970) 0.87
Effects of P 1 and ADP on ATPase activity in chloroplasts. Biochim Biophys Acta (1972) 0.86
Tightly bound adenosine diphosphate, which inhibits the activity of mitochondrial F1-ATPase, is located at the catalytic site of the enzyme. FEBS Lett (1985) 0.86
Energy-linked binding of Pi is required for continuous steady-state proton-translocating ATP hydrolysis catalyzed by F0.F1 ATP synthase. Biochemistry (2006) 0.85
Activation of the H(+)-ATP synthase in the photosynthetic bacterium Rhodobacter capsulatus. J Biol Chem (1992) 0.80
Chemical modification of mono-cysteine mutants allows a more global look at conformations of the epsilon subunit of the ATP synthase from Escherichia coli. J Bioenerg Biomembr (2007) 0.78
Interactions of inorganic phosphate with spinach coupling factor 1. Effects on ATPase and ADP binding activities. J Biol Chem (1981) 0.78
Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization. Nat Cell Biol (2003) 4.79
Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation. Cell (2007) 4.09
Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators. Proc Natl Acad Sci U S A (2009) 3.57
Ultrafine membrane compartments for molecular diffusion as revealed by single molecule techniques. Biophys J (2004) 3.54
Mechanically driven ATP synthesis by F1-ATPase. Nature (2004) 3.45
Chemomechanical coupling in F1-ATPase revealed by simultaneous observation of nucleotide kinetics and rotation. Nat Struct Mol Biol (2004) 3.23
The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell (2003) 2.89
Single-molecule imaging analysis of Ras activation in living cells. Proc Natl Acad Sci U S A (2004) 2.84
Catalysis and rotation of F1 motor: cleavage of ATP at the catalytic site occurs in 1 ms before 40 degree substep rotation. Proc Natl Acad Sci U S A (2003) 2.65
High-speed atomic force microscopy reveals rotary catalysis of rotorless F₁-ATPase. Science (2011) 2.56
GPI-anchored receptor clusters transiently recruit Lyn and G alpha for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1. J Cell Biol (2007) 2.54
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. J Cell Sci (2004) 2.07
Fluorescence imaging for monitoring the colocalization of two single molecules in living cells. Biophys J (2004) 1.99
Myosin V is a left-handed spiral motor on the right-handed actin helix. Nat Struct Biol (2002) 1.95
Evidence for rotation of V1-ATPase. Proc Natl Acad Sci U S A (2003) 1.84
beta-Helix is a likely core structure of yeast prion Sup35 amyloid fibers. Biochem Biophys Res Commun (2004) 1.83
Escherichia coli phage-shock protein A (PspA) binds to membrane phospholipids and repairs proton leakage of the damaged membranes. Mol Microbiol (2007) 1.74
Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase. Proc Natl Acad Sci U S A (2003) 1.66
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. J Biol Chem (2003) 1.65
Phosphate release in F1-ATPase catalytic cycle follows ADP release. Nat Chem Biol (2010) 1.65
Cooperative three-step motions in catalytic subunits of F(1)-ATPase correlate with 80 degrees and 40 degrees substep rotations. Nat Struct Mol Biol (2008) 1.63
Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin. PLoS Biol (2011) 1.57
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J (2007) 1.55
Myosin V walks by lever action and Brownian motion. Science (2007) 1.54
F1-ATPase rotates by an asymmetric, sequential mechanism using all three catalytic subunits. Nat Struct Mol Biol (2007) 1.53
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J Biol Chem (2003) 1.52
Thermophilic ATP synthase has a decamer c-ring: indication of noninteger 10:3 H+/ATP ratio and permissive elastic coupling. Proc Natl Acad Sci U S A (2004) 1.48
Structure of the whole cytosolic region of ATP-dependent protease FtsH. Mol Cell (2006) 1.46
Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J Biol Chem (2002) 1.46
Mechanism of Lck recruitment to the T-cell receptor cluster as studied by single-molecule-fluorescence video imaging. Chemphyschem (2003) 1.44
ATP-driven stepwise rotation of FoF1-ATP synthase. Proc Natl Acad Sci U S A (2005) 1.43
Activation of pausing F1 motor by external force. Proc Natl Acad Sci U S A (2005) 1.41
One rotary mechanism for F1-ATPase over ATP concentrations from millimolar down to nanomolar. Biophys J (2004) 1.40
Axle-less F1-ATPase rotates in the correct direction. Science (2008) 1.36
GroEL mediates protein folding with a two successive timer mechanism. Mol Cell (2004) 1.36
Subunit arrangement in V-ATPase from Thermus thermophilus. J Biol Chem (2003) 1.36
F0F1-ATPase/synthase is geared to the synthesis mode by conformational rearrangement of epsilon subunit in response to proton motive force and ADP/ATP balance. J Biol Chem (2003) 1.36
Chemo-mechanical coupling in F(1)-ATPase revealed by catalytic site occupancy during catalysis. Biophys J (2010) 1.35
The ATP-waiting conformation of rotating F1-ATPase revealed by single-pair fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (2003) 1.34
Hsp104 binds to yeast Sup35 prion fiber but needs other factor(s) to sever it. J Biol Chem (2004) 1.34
Dodecamer rotor ring defines H+/ATP ratio for ATP synthesis of prokaryotic V-ATPase from Thermus thermophilus. Proc Natl Acad Sci U S A (2007) 1.33
Mechanical modulation of catalytic power on F1-ATPase. Nat Chem Biol (2011) 1.33
Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. J Biol Chem (2006) 1.32
Structures of the thermophilic F1-ATPase epsilon subunit suggesting ATP-regulated arm motion of its C-terminal domain in F1. Proc Natl Acad Sci U S A (2007) 1.30
Rotation scheme of V1-motor is different from that of F1-motor. Proc Natl Acad Sci U S A (2005) 1.28
Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. J Biol Chem (2004) 1.26
F(0) of ATP synthase is a rotary proton channel. Obligatory coupling of proton translocation with rotation of c-subunit ring. J Biol Chem (2002) 1.25
Fluctuation theorem applied to F1-ATPase. Phys Rev Lett (2010) 1.25
Correlation between the conformational states of F1-ATPase as determined from its crystal structure and single-molecule rotation. Proc Natl Acad Sci U S A (2008) 1.25
Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. Biochem J (2007) 1.24
Unconstrained steps of myosin VI appear longest among known molecular motors. Biophys J (2004) 1.24
Crystal structure of the native chaperonin complex from Thermus thermophilus revealed unexpected asymmetry at the cis-cavity. Structure (2004) 1.23
Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus. EMBO J (2005) 1.21
Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8. Structure (2002) 1.20
ATP hydrolysis and synthesis of a rotary motor V-ATPase from Thermus thermophilus. J Biol Chem (2008) 1.20
Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. J Biol Chem (2006) 1.19
Rotation of the proteolipid ring in the V-ATPase. J Biol Chem (2003) 1.18
X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain. J Biol Chem (2008) 1.17
BeF(x) stops the chaperonin cycle of GroEL-GroES and generates a complex with double folding chambers. J Biol Chem (2004) 1.16
Simple dark-field microscopy with nanometer spatial precision and microsecond temporal resolution. Biophys J (2010) 1.16
Rotation and structure of FoF1-ATP synthase. J Biochem (2011) 1.15
Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. PLoS One (2006) 1.14
Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice. J Neurosci (2011) 1.14
Crystal structure of A3B3 complex of V-ATPase from Thermus thermophilus. EMBO J (2009) 1.14
Discrimination of ATP, ADP, and AMPPNP by chaperonin GroEL: hexokinase treatment revealed the exclusive role of ATP. J Biol Chem (2003) 1.14
Roles of the two ATP binding sites of ClpB from Thermus thermophilus. J Biol Chem (2001) 1.13
Stiffness of γ subunit of F(1)-ATPase. Eur Biophys J (2010) 1.12
The role of subunit epsilon in the catalysis and regulation of FOF1-ATP synthase. Biochim Biophys Acta (2006) 1.12
Temperature-sensitive reaction intermediate of F1-ATPase. EMBO Rep (2007) 1.11
Isolated epsilon subunit of thermophilic F1-ATPase binds ATP. J Biol Chem (2003) 1.09
Low dielectric permittivity of water at the membrane interface: effect on the energy coupling mechanism in biological membranes. Biophys J (2003) 1.09
Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. J Biol Chem (2002) 1.09
Resolving stepping rotation in Thermus thermophilus H(+)-ATPase/synthase with an essentially drag-free probe. Nat Commun (2011) 1.08
Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria. J Biol Chem (2011) 1.08
Evaluation of multidrug efflux pump inhibitors by a new method using microfluidic channels. PLoS One (2011) 1.07
Ribosomal protein L2 associates with E. coli HtpG and activates its ATPase activity. Biochem Biophys Res Commun (2010) 1.07
Revisiting the GroEL-GroES reaction cycle via the symmetric intermediate implied by novel aspects of the GroEL(D398A) mutant. J Biol Chem (2008) 1.07
Real-time monitoring of conformational dynamics of the epsilon subunit in F1-ATPase. J Biol Chem (2005) 1.07
F1-ATPase changes its conformations upon phosphate release. J Biol Chem (2002) 1.07
Dynamics of yeast prion aggregates in single living cells. Genes Cells (2006) 1.07