Effect of Light on Human Circadian Physiology.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 20161220)

Published in Sleep Med Clin on June 01, 2009

Authors

Jeanne F Duffy, Charles A Czeisler

Articles citing this

Human blood metabolite timetable indicates internal body time. Proc Natl Acad Sci U S A (2012) 1.37

Amplitude reduction and phase shifts of melatonin, cortisol and other circadian rhythms after a gradual advance of sleep and light exposure in humans. PLoS One (2012) 1.00

Pharmacology of myopia and potential role for intrinsic retinal circadian rhythms. Exp Eye Res (2013) 0.95

Combination of light and melatonin time cues for phase advancing the human circadian clock. Sleep (2013) 0.93

How to fix a broken clock. Trends Pharmacol Sci (2013) 0.88

No time to lose: workshop on circadian rhythms and metabolic disease. Genes Dev (2010) 0.86

Millisecond flashes of light phase delay the human circadian clock during sleep. J Biol Rhythms (2014) 0.85

Abnormal hypothalamic response to light in seasonal affective disorder. Biol Psychiatry (2011) 0.81

Efficacy and tolerability of agomelatine in the treatment of depression. Patient Prefer Adherence (2014) 0.81

Young Adults' Sleep Duration on Work Days: Differences between East and West. Front Neurol (2014) 0.81

Aging and Circadian Rhythms. Sleep Med Clin (2015) 0.80

Direct Measurements of Smartphone Screen-Time: Relationships with Demographics and Sleep. PLoS One (2016) 0.78

Sustained wakefulness and visual attention: moderation by chronotype. Exp Brain Res (2016) 0.77

Electroencephalographic signals synchronize with behaviors and are sexually dimorphic during the light-dark cycle in reproductive frogs. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2013) 0.77

Estimation methods for human circadian phase by use of peripheral tissues. Hypertens Res (2016) 0.77

Post-exercise cold water immersion: effect on core temperature and melatonin responses. Eur J Appl Physiol (2012) 0.76

Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(-/-) mice, but not wildtype mice. Sci Rep (2017) 0.75

Relationship between Daytime Sleepiness and Intrinsically Photosensitive Retinal Ganglion Cells in Glaucomatous Disease. J Ophthalmol (2016) 0.75

Exploration of Circadian Rhythms in Patients with Bilateral Vestibular Loss. PLoS One (2016) 0.75

The Zurich 3-step concept for the management of behavioral sleep disorders in children: a before-and-after study. J Clin Sleep Med (2015) 0.75

Sleep, Melatonin, and the Menopausal Transition: What Are the Links? Sleep Sci (2017) 0.75

Education Intervention on Chronotherapy for Final-Year Pharmacy Students. Pharmacy (Basel) (2015) 0.75

Articles cited by this

(truncated to the top 100)

Phototransduction by retinal ganglion cells that set the circadian clock. Science (2002) 10.42

Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science (2002) 9.08

Stability, precision, and near-24-hour period of the human circadian pacemaker. Science (1999) 7.74

Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature (2003) 5.84

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron (1995) 5.70

Transplanted suprachiasmatic nucleus determines circadian period. Science (1990) 5.55

Circadian rhythms and the circadian organization of living systems. Cold Spring Harb Symp Quant Biol (1960) 5.34

Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Natl Acad Sci U S A (1972) 4.65

Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision. Nature (2008) 4.55

Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression. J Physiol (2000) 4.39

Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor. J Neurosci (2001) 4.36

A novel human opsin in the inner retina. J Neurosci (2000) 4.30

Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors. Science (1999) 3.96

Light suppresses melatonin secretion in humans. Science (1980) 3.45

Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science (1999) 3.41

An action spectrum for melatonin suppression: evidence for a novel non-rod, non-cone photoreceptor system in humans. J Physiol (2001) 3.34

A phase response curve to single bright light pulses in human subjects. J Physiol (2003) 3.29

Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans. Nat Med (1999) 3.27

Suppression of melatonin secretion in some blind patients by exposure to bright light. N Engl J Med (1995) 3.08

Exposure to bright light and darkness to treat physiologic maladaptation to night work. N Engl J Med (1990) 3.01

Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans. Sleep (2006) 2.94

Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci (2001) 2.79

Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina. Curr Biol (2007) 2.68

High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light. J Clin Endocrinol Metab (2003) 2.67

Bright light induction of strong (type 0) resetting of the human circadian pacemaker. Science (1989) 2.66

Circadian temperature and melatonin rhythms, sleep, and neurobehavioral function in humans living on a 20-h day. Am J Physiol (1999) 2.60

Dose-response relationships for resetting of human circadian clock by light. Nature (1996) 2.56

A retinohypothalamic projection in the rat. J Comp Neurol (1972) 2.36

Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase. Behav Neurosci (2001) 2.24

The effects of prior light history on the suppression of melatonin by light in humans. J Pineal Res (2002) 2.18

Sensitivity and integration in a visual pathway for circadian entrainment in the hamster (Mesocricetus auratus). J Physiol (1991) 2.06

Circadian rhythm sleep disorders: part I, basic principles, shift work and jet lag disorders. An American Academy of Sleep Medicine review. Sleep (2007) 2.05

The suprachiasmatic nucleus: a 25-year retrospective. J Biol Rhythms (1998) 2.03

Dose-response relationship for light intensity and ocular and electroencephalographic correlates of human alertness. Behav Brain Res (2000) 2.01

Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle. Science (1986) 1.98

Photoreceptor adaptation in intrinsically photosensitive retinal ganglion cells. Neuron (2005) 1.96

Individual differences in the phase and amplitude of the human circadian temperature rhythm: with an emphasis on morningness-eveningness. J Sleep Res (2000) 1.95

Spectral sensitivity of a novel photoreceptive system mediating entrainment of mammalian circadian rhythms. Nature (1984) 1.94

Relationship of endogenous circadian melatonin and temperature rhythms to self-reported preference for morning or evening activity in young and older people. J Investig Med (1999) 1.91

The retinohypothalamic tract originates from a distinct subset of retinal ganglion cells. J Comp Neurol (1995) 1.82

Circadian photoreception in the retinally degenerate mouse (rd/rd). J Comp Physiol A (1991) 1.81

Responses of neurones of the rat suprachiasmatic nucleus to retinal illumination under photopic and scotopic conditions. J Physiol (2000) 1.78

A human phase-response curve to light. Neurosci Lett (1991) 1.72

Entrainment of the human circadian pacemaker to longer-than-24-h days. Proc Natl Acad Sci U S A (2007) 1.70

Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans. Proc Natl Acad Sci U S A (2001) 1.66

Light-induced melatonin suppression in humans with polychromatic and monochromatic light. Chronobiol Int (2007) 1.63

Entrainment of the human circadian system by light. J Biol Rhythms (2005) 1.63

Later endogenous circadian temperature nadir relative to an earlier wake time in older people. Am J Physiol (1998) 1.62

Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans. J Biol Rhythms (2005) 1.56

Adaptation of human pineal melatonin suppression by recent photic history. J Clin Endocrinol Metab (2004) 1.54

Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness. Sleep (2004) 1.54

Efficacy of a single sequence of intermittent bright light pulses for delaying circadian phase in humans. Am J Physiol Endocrinol Metab (2004) 1.50

Phototransduction in ganglion-cell photoreceptors. Pflugers Arch (2007) 1.49

Integrated view of resetting a circadian clock. J Theor Biol (1970) 1.47

Quantifying human circadian pacemaker response to brief, extended, and repeated light stimuli over the phototopic range. J Biol Rhythms (1999) 1.44

Sleep and circadian rhythms in humans. Cold Spring Harb Symp Quant Biol (2007) 1.43

Human melatonin suppression by light is intensity dependent. J Pineal Res (1989) 1.32

Photic resetting of the human circadian pacemaker in the absence of conscious vision. J Biol Rhythms (2002) 1.31

Phase-shifting human circadian rhythms: influence of sleep timing, social contact and light exposure. J Physiol (1996) 1.25

Human circadian rhythms in continuous darkness: entrainment by social cues. Science (1971) 1.22

Plasticity of the intrinsic period of the human circadian timing system. PLoS One (2007) 1.21

Intrinsic circadian period of adolescent humans measured in conditions of forced desynchrony. Neurosci Lett (1999) 1.20

Temporal dynamics of late-night photic stimulation of the human circadian timing system. Am J Physiol Regul Integr Comp Physiol (2005) 1.17

Seasonal and diurnal patterns of human illumination under natural conditions. Chronobiol Int (1998) 1.17

Suppression of nocturnal plasma melatonin and 6-sulphatoxymelatonin by bright and dim light in man. Horm Metab Res (1987) 1.16

Light treatment for sleep disorders: consensus report. VII. Jet lag. J Biol Rhythms (1995) 1.16

Light-induced suppression of endogenous circadian amplitude in humans. Nature (1991) 1.15

Human circadian pacemaker is sensitive to light throughout subjective day without evidence of transients. Am J Physiol (1997) 1.15

Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjects. Neurobiol Aging (2006) 1.15

Dynamic resetting of the human circadian pacemaker by intermittent bright light. Am J Physiol Regul Integr Comp Physiol (2000) 1.14

Nonentrained circadian rhythms of melatonin in submariners scheduled to an 18-hour day. J Biol Rhythms (1999) 1.12

Human circadian rhythms in constant dim light (8 lux) with knowledge of clock time. J Sleep Res (1996) 1.11

Dose-response relationship between light irradiance and the suppression of plasma melatonin in human volunteers. Brain Res (1988) 1.09

Integration and saturation within the circadian photic entrainment pathway of hamsters. Am J Physiol (1999) 1.08

Retinohypothalamic projection in mammals: a comparative study. Brain Res (1973) 1.07

Circadian system of mice integrates brief light stimuli. Am J Physiol (1998) 1.07

Daily light sensitivity rhythm in a rodent. Science (1960) 1.05

Seasonal variation in human illumination exposure at two different latitudes. J Biol Rhythms (1995) 1.04

A limit cycle interpretation of a mosquito circadian oscillator. J Theor Biol (1980) 1.04

Persistence of the circadian thyrotropin rhythm under constant conditions and after light-induced shifts of circadian phase. J Clin Endocrinol Metab (1994) 1.03

Light treatment for sleep disorders: consensus report. VI. Shift work. J Biol Rhythms (1995) 1.02

Efficacy of bright light and sleep/darkness scheduling in alleviating circadian maladaptation to night work. Am J Physiol Endocrinol Metab (2001) 1.02

Scheduling of sleep/darkness affects the circadian phase of night shift workers. Neurosci Lett (2005) 1.01

Circadian phase in delayed sleep phase syndrome: predictors and temporal stability across multiple assessments. Sleep (2006) 0.99

Comparison of visual sensitivity for suppression of pineal melatonin and circadian phase-shifting in the golden hamster. Brain Res (1991) 0.98

Sensitivity of the human circadian pacemaker to moderately bright light. J Biol Rhythms (1994) 0.98

Melatonin suppression in human subjects by bright and dim light in antarctica: time and season-dependent effects. Neurosci Lett (1992) 0.97

The suppression of pineal melatonin content and N-acetyltransferase activity by different light irradiances in the Syrian hamster: a dose-response relationship. Endocrinology (1983) 0.96

Intermittent bright light and exercise to entrain human circadian rhythms to night work. Am J Physiol (1999) 0.95

Relationship between light intensity and phase resetting in a mammalian circadian system. J Exp Zool (1999) 0.93

Photopic transduction implicated in human circadian entrainment. Neurosci Lett (1997) 0.92

Exercise distributed across day and night does not alter circadian period in humans. J Biol Rhythms (2007) 0.90

Irradiance responsivity and unequivocal type-1 phase responsivity of rat circadian activity rhythms. Am J Physiol (1992) 0.90

Shaping the light/dark pattern for circadian adaptation to night shift work. Physiol Behav (2008) 0.89

[Strength of a light-dark cycle as a time determiner for circadian rhythm in man]. Pflugers Arch (1970) 0.88

The relation between light-induced discharge in the suprachiasmatic nucleus and phase shifts of hamster circadian rhythms. Brain Res (1992) 0.88

Dark adaptation in the circadian system of the mouse. Physiol Behav (2001) 0.87

Light treatment for sleep disorders: consensus report. IV. Sleep phase and duration disturbances. J Biol Rhythms (1995) 0.87

Light of domestic intensity produces phase shifts of the circadian oscillator in humans. Neurosci Lett (1998) 0.87

The timing of the human circadian clock is accurately represented by the core body temperature rhythm following phase shifts to a three-cycle light stimulus near the critical zone. J Biol Rhythms (2000) 0.86

Articles by these authors

Effect of reducing interns' work hours on serious medical errors in intensive care units. N Engl J Med (2004) 13.16

Extended work shifts and the risk of motor vehicle crashes among interns. N Engl J Med (2005) 8.73

Effect of reducing interns' weekly work hours on sleep and attentional failures. N Engl J Med (2004) 7.37

The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care. Crit Care Med (2005) 4.98

A phase response curve to single bright light pulses in human subjects. J Physiol (2003) 3.29

Extended work duration and the risk of self-reported percutaneous injuries in interns. JAMA (2006) 3.26

Impact of extended-duration shifts on medical errors, adverse events, and attentional failures. PLoS Med (2006) 3.22

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption. Sci Transl Med (2012) 3.08

Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans. Sleep (2006) 2.94

Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina. Curr Biol (2007) 2.68

High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light. J Clin Endocrinol Metab (2003) 2.67

Comparisons of the variability of three markers of the human circadian pacemaker. J Biol Rhythms (2002) 2.64

Sleep deprivation, elective surgical procedures, and informed consent. N Engl J Med (2010) 2.21

Sleep disorders, health, and safety in police officers. JAMA (2011) 2.16

Risks of complications by attending physicians after performing nighttime procedures. JAMA (2009) 2.16

Relationship between alertness, performance, and body temperature in humans. Am J Physiol Regul Integr Comp Physiol (2002) 2.15

Sex difference in the near-24-hour intrinsic period of the human circadian timing system. Proc Natl Acad Sci U S A (2011) 1.97

Sleep-facilitating effect of exogenous melatonin in healthy young men and women is circadian-phase dependent. Sleep (2006) 1.80

A common polymorphism near PER1 and the timing of human behavioral rhythms. Ann Neurol (2012) 1.79

Effects of health care provider work hours and sleep deprivation on safety and performance. Jt Comm J Qual Patient Saf (2007) 1.78

Entrainment of the human circadian pacemaker to longer-than-24-h days. Proc Natl Acad Sci U S A (2007) 1.70

Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light. Sci Transl Med (2010) 1.70

Interns' compliance with accreditation council for graduate medical education work-hour limits. JAMA (2006) 1.69

Uncovering residual effects of chronic sleep loss on human performance. Sci Transl Med (2010) 1.66

Absence of circadian phase resetting in response to bright light behind the knees. Science (2002) 1.60

Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans. J Biol Rhythms (2005) 1.56

Adaptation of human pineal melatonin suppression by recent photic history. J Clin Endocrinol Metab (2004) 1.54

Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness. Sleep (2004) 1.54

Acute sleep deprivation and circadian misalignment associated with transition onto the first night of work impairs visual selective attention. PLoS One (2007) 1.50

Efficacy of a single sequence of intermittent bright light pulses for delaying circadian phase in humans. Am J Physiol Endocrinol Metab (2004) 1.50

Implementing the 2009 Institute of Medicine recommendations on resident physician work hours, supervision, and safety. Nat Sci Sleep (2011) 1.46

Peak of circadian melatonin rhythm occurs later within the sleep of older subjects. Am J Physiol Endocrinol Metab (2002) 1.46

Sleep and wakefulness out of phase with internal biological time impairs learning in humans. J Cogn Neurosci (2006) 1.44

Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. J Clin Endocrinol Metab (2010) 1.43

The sleep and technology use of Americans: findings from the National Sleep Foundation's 2011 Sleep in America poll. J Clin Sleep Med (2013) 1.41

Headache and sleep: also assess circadian rhythm sleep disorders. Headache (2014) 1.39

Sex differences in phase angle of entrainment and melatonin amplitude in humans. J Biol Rhythms (2010) 1.30

The human circadian system adapts to prior photic history. J Physiol (2011) 1.27

Healthy older adults better tolerate sleep deprivation than young adults. J Am Geriatr Soc (2009) 1.27

Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans. J Neurosci (2012) 1.25

Human phase response curve to a 1 h pulse of bright white light. J Physiol (2012) 1.23

Searching night and day: a dissociation of effects of circadian phase and time awake on visual selective attention and vigilance. Psychol Sci (2003) 1.23

Plasticity of the intrinsic period of the human circadian timing system. PLoS One (2007) 1.21

Effective implementation of work-hour limits and systemic improvements. Jt Comm J Qual Patient Saf (2007) 1.19

Temporal dynamics of late-night photic stimulation of the human circadian timing system. Am J Physiol Regul Integr Comp Physiol (2005) 1.17

Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjects. Neurobiol Aging (2006) 1.15

Age-related change in the relationship between circadian period, circadian phase, and diurnal preference in humans. Neurosci Lett (2002) 1.13

Melatonin, sleep, and circadian rhythms. Sleep Med Rev (2005) 1.13

Light exposure patterns in healthy older and young adults. J Biol Rhythms (2010) 1.12

US public opinion regarding proposed limits on resident physician work hours. BMC Med (2010) 1.12

Sleep disruption among older men and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev (2013) 1.10

Polysomnographic respiratory abnormalities in asymptomatic individuals. Sleep (2008) 1.09

Older people awaken more frequently but fall back asleep at the same rate as younger people. Sleep (2004) 1.09

Human responses to bright light of different durations. J Physiol (2012) 1.08

When policy meets physiology: the challenge of reducing resident work hours. Clin Orthop Relat Res (2006) 1.08

Circadian and wake-dependent influences on subjective sleepiness, cognitive throughput, and reaction time performance in older and young adults. Sleep (2010) 1.03

Scheduling of sleep/darkness affects the circadian phase of night shift workers. Neurosci Lett (2005) 1.01

Amplitude reduction and phase shifts of melatonin, cortisol and other circadian rhythms after a gradual advance of sleep and light exposure in humans. PLoS One (2012) 1.00

Plasma melatonin rhythms in young and older humans during sleep, sleep deprivation, and wake. Sleep (2007) 1.00

The impact of sleep timing and bright light exposure on attentional impairment during night work. J Biol Rhythms (2008) 1.00

Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light. Am J Physiol Regul Integr Comp Physiol (2004) 0.99

Comparison of subjective and objective assessments of sleep in healthy older subjects without sleep complaints. J Sleep Res (2009) 0.96

The influence of subjective alertness and motivation on human performance independent of circadian and homeostatic regulation. J Biol Rhythms (2003) 0.96

Effects of sleep inertia on cognition. JAMA (2006) 0.96

Employer-mandated sleep apnea screening and diagnosis in commercial drivers. J Occup Environ Med (2012) 0.95

Blue light stimulates cognitive brain activity in visually blind individuals. J Cogn Neurosci (2013) 0.95

Differential impact of chronotype on weekday and weekend sleep timing and duration. Nat Sci Sleep (2010) 0.95

Human phase response curve to a single 6.5 h pulse of short-wavelength light. J Physiol (2012) 0.95

Sleep inertia varies with circadian phase and sleep stage in older adults. Behav Neurosci (2008) 0.94

Acute effects of bright light exposure on cortisol levels. J Biol Rhythms (2010) 0.94

Addition of a non-photic component to a light-based mathematical model of the human circadian pacemaker. J Theor Biol (2007) 0.93

Recovery from medical errors: the critical care nursing safety net. Jt Comm J Qual Patient Saf (2006) 0.93

One night of sleep deprivation affects reaction time, but not interference or facilitation in a Stroop task. Brain Cogn (2011) 0.92

Comparison of sustained attention assessed by auditory and visual psychomotor vigilance tasks prior to and during sleep deprivation. J Sleep Res (2010) 0.91

Revisiting spontaneous internal desynchrony using a quantitative model of sleep physiology. J Biol Rhythms (2011) 0.91

Survival analysis indicates that age-related decline in sleep continuity occurs exclusively during NREM sleep. Neurobiol Aging (2012) 0.91

Exercise distributed across day and night does not alter circadian period in humans. J Biol Rhythms (2007) 0.90

Neurobehavioral performance in young adults living on a 28-h day for 6 weeks. Sleep (2009) 0.90

Sleep duration in midlife and later life in relation to cognition. J Am Geriatr Soc (2014) 0.90

The challenges and opportunities of technological approaches to fatigue management. Accid Anal Prev (2011) 0.89

Bilateral oculosympathetic paresis associated with loss of nocturnal melatonin secretion in patients with spinal cord injury. J Spinal Cord Med (2005) 0.88

Effect of modafinil on impairments in neurobehavioral performance and learning associated with extended wakefulness and circadian misalignment. Neuropsychopharmacology (2010) 0.88

Diurnal variation in CSF orexin-A in healthy male subjects. Sleep (2006) 0.88

Direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans depend on prior light history. Sleep (2013) 0.87

Laboratory validation of an in-home method for assessing circadian phase using dim light melatonin onset (DLMO). Sleep Med (2012) 0.86

Evaluation of a single-channel nasal pressure device to assess obstructive sleep apnea risk in laboratory and home environments. J Clin Sleep Med (2013) 0.86

Assessment of drowsiness based on ocular parameters detected by infrared reflectance oculography. J Clin Sleep Med (2013) 0.86