Published in Nature on June 15, 2003
Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu Rev Genomics Hum Genet (2004) 7.50
Central projections of melanopsin-expressing retinal ganglion cells in the mouse. J Comp Neurol (2006) 4.64
Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision. Nature (2008) 4.55
Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver. J Biol Chem (2003) 3.16
Clocks not winding down: unravelling circadian networks. Nat Rev Mol Cell Biol (2010) 2.95
Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information. Cell (2007) 2.94
Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision. Neuron (2010) 2.91
Genetics of circadian rhythms in Mammalian model organisms. Adv Genet (2011) 2.80
Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses. PLoS One (2008) 2.69
Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina. Curr Biol (2007) 2.68
The mammalian circadian timing system: from gene expression to physiology. Chromosoma (2004) 2.67
Synaptic influences on rat ganglion-cell photoreceptors. J Physiol (2007) 2.66
Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Vision Res (2007) 2.64
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell (2009) 2.63
The opsins. Genome Biol (2005) 2.45
A neural mechanism for exacerbation of headache by light. Nat Neurosci (2010) 2.26
Phototransduction in mouse rods and cones. Pflugers Arch (2007) 2.23
Intraretinal signaling by ganglion cell photoreceptors to dopaminergic amacrine neurons. Proc Natl Acad Sci U S A (2008) 2.19
Modeling the role of mid-wavelength cones in circadian responses to light. Neuron (2007) 2.12
Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs. Nature (2011) 2.10
Intrinsically photosensitive retinal ganglion cells. Physiol Rev (2010) 2.09
Photon capture and signalling by melanopsin retinal ganglion cells. Nature (2008) 2.08
Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates. PLoS Biol (2006) 2.05
The cryptochromes. Genome Biol (2005) 2.02
Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance. Neuron (2010) 1.96
Melanopsin-dependent nonvisual responses: evidence for photopigment bistability in vivo. J Biol Rhythms (2007) 1.88
Leber congenital amaurosis due to RPE65 mutations and its treatment with gene therapy. Prog Retin Eye Res (2010) 1.81
Rods-cones and melanopsin detect light and dark to modulate sleep independent of image formation. Proc Natl Acad Sci U S A (2008) 1.75
Measuring and using light in the melanopsin age. Trends Neurosci (2013) 1.75
Melanopsin-driven light adaptation in mouse vision. Curr Biol (2014) 1.75
Evolution of opsins and phototransduction. Philos Trans R Soc Lond B Biol Sci (2009) 1.72
Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light. Sci Transl Med (2010) 1.70
Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina. Curr Biol (2005) 1.69
Targeted destruction of photosensitive retinal ganglion cells with a saporin conjugate alters the effects of light on mouse circadian rhythms. PLoS One (2008) 1.69
Genome-wide analysis of light- and temperature-entrained circadian transcripts in Caenorhabditis elegans. PLoS Biol (2010) 1.68
The influence of intrinsically-photosensitive retinal ganglion cells on the spectral sensitivity and response dynamics of the human pupillary light reflex. Vision Res (2010) 1.65
Rod photoreceptors drive circadian photoentrainment across a wide range of light intensities. Nat Neurosci (2010) 1.63
The evolution of irradiance detection: melanopsin and the non-visual opsins. Philos Trans R Soc Lond B Biol Sci (2009) 1.63
Melanopsin signalling in mammalian iris and retina. Nature (2011) 1.61
Neurobiological mechanisms for the regulation of mammalian sleep-wake behavior: reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence. Neurosci Biobehav Rev (2007) 1.57
Genome of the Chinese tree shrew. Nat Commun (2013) 1.55
Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin. Proc Natl Acad Sci U S A (2005) 1.54
LiGluR restores visual responses in rodent models of inherited blindness. Mol Ther (2011) 1.53
The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. PLoS Biol (2014) 1.52
Finding new clock components: past and future. J Biol Rhythms (2004) 1.50
Efficacy of a single sequence of intermittent bright light pulses for delaying circadian phase in humans. Am J Physiol Endocrinol Metab (2004) 1.50
Phototransduction in ganglion-cell photoreceptors. Pflugers Arch (2007) 1.49
Violet and blue light blocking intraocular lenses: photoprotection versus photoreception. Br J Ophthalmol (2006) 1.49
A mammalian neural tissue opsin (Opsin 5) is a deep brain photoreceptor in birds. Proc Natl Acad Sci U S A (2010) 1.48
Melanopsin-dependent light avoidance in neonatal mice. Proc Natl Acad Sci U S A (2010) 1.45
The optokinetic reflex as a tool for quantitative analyses of nervous system function in mice: application to genetic and drug-induced variation. PLoS One (2008) 1.44
Automated assessment of pavlovian conditioned freezing and shock reactivity in mice using the video freeze system. Front Behav Neurosci (2010) 1.41
Impact of behavior on central and peripheral circadian clocks in the common vole Microtus arvalis, a mammal with ultradian rhythms. Proc Natl Acad Sci U S A (2006) 1.40
Circadian system, sleep and endocrinology. Mol Cell Endocrinol (2011) 1.38
Effects of circadian disruption on the cardiometabolic system. Rev Endocr Metab Disord (2009) 1.36
Diurnal mice (Mus musculus) and other examples of temporal niche switching. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2005) 1.34
Non-image-forming ocular photoreception in vertebrates. Curr Opin Neurobiol (2005) 1.33
Structure of cone photoreceptors. Prog Retin Eye Res (2009) 1.32
Drosophila visual transduction. Trends Neurosci (2012) 1.32
The emerging roles of melanopsin in behavioral adaptation to light. Trends Mol Med (2010) 1.31
Breast cancer and circadian disruption from electric lighting in the modern world. CA Cancer J Clin (2013) 1.31
Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells. Neuron (2014) 1.29
Brain responses to violet, blue, and green monochromatic light exposures in humans: prominent role of blue light and the brainstem. PLoS One (2007) 1.28
Synaptic inputs to retinal ganglion cells that set the circadian clock. Eur J Neurosci (2006) 1.28
Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans. J Neurosci (2012) 1.25
Contribution of human melanopsin retinal ganglion cells to steady-state pupil responses. Proc Biol Sci (2010) 1.23
Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina. J Neurosci (2009) 1.22
Regulation of prokineticin 2 expression by light and the circadian clock. BMC Neurosci (2005) 1.19
Human melanopsin forms a pigment maximally sensitive to blue light (λmax ≈ 479 nm) supporting activation of G(q/11) and G(i/o) signalling cascades. Proc Biol Sci (2013) 1.19
Glaucoma alters the circadian timing system. PLoS One (2008) 1.17
Spectral quality of light modulates emotional brain responses in humans. Proc Natl Acad Sci U S A (2010) 1.16
Photochemistry of retinal chromophore in mouse melanopsin. Proc Natl Acad Sci U S A (2008) 1.16
Light as a central modulator of circadian rhythms, sleep and affect. Nat Rev Neurosci (2014) 1.14
UV-sensitive photoreceptor protein OPN5 in humans and mice. PLoS One (2011) 1.13
Melanopsin and mechanisms of non-visual ocular photoreception. J Biol Chem (2011) 1.12
A missense variant (P10L) of the melanopsin (OPN4) gene in seasonal affective disorder. J Affect Disord (2008) 1.09
Inner retinal photoreception independent of the visual retinoid cycle. Proc Natl Acad Sci U S A (2006) 1.09
Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice. Invest Ophthalmol Vis Sci (2005) 1.08
Nonvisual light responses in the Rpe65 knockout mouse: rod loss restores sensitivity to the melanopsin system. Proc Natl Acad Sci U S A (2006) 1.08
The circadian response of intrinsically photosensitive retinal ganglion cells. PLoS One (2011) 1.06
Melanopsin is highly resistant to light and chemical bleaching in vivo. J Biol Chem (2012) 1.06
Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function. J Biol Chem (2011) 1.06
Impact of cataract surgery on sleep in patients receiving either ultraviolet-blocking or blue-filtering intraocular lens implants. Invest Ophthalmol Vis Sci (2014) 1.05
Aging in the circadian system: considerations for health, disease prevention and longevity. Exp Gerontol (2008) 1.05
Absence of normal photic integration in the circadian visual system: response to millisecond light flashes. J Neurosci (2007) 1.05
Effects of spectral transmittance through standard laboratory cages on circadian metabolism and physiology in nude rats. J Am Assoc Lab Anim Sci (2013) 1.04
Identification of nonvisual photomotor response cells in the vertebrate hindbrain. J Neurosci (2013) 1.04
Photoresponse diversity among the five types of intrinsically photosensitive retinal ganglion cells. J Physiol (2014) 1.04
Retinal pathways influence temporal niche. Proc Natl Acad Sci U S A (2008) 1.03
Effect of Light on Human Circadian Physiology. Sleep Med Clin (2009) 1.02
Unexpected diversity and photoperiod dependence of the zebrafish melanopsin system. PLoS One (2011) 1.02
Retinofugal projections in the mouse. J Comp Neurol (2014) 1.00
Evidence for multiple phototransduction pathways in a reef-building coral. PLoS One (2012) 1.00
Visual responses in mice lacking critical components of all known retinal phototransduction cascades. PLoS One (2010) 1.00
Classical and melanopsin photoreception in irradiance detection: negative masking of locomotor activity by light. Eur J Neurosci (2008) 0.99
Diverse types of ganglion cell photoreceptors in the mammalian retina. Prog Retin Eye Res (2012) 0.99
Dissecting a role for melanopsin in behavioural light aversion reveals a response independent of conventional photoreception. PLoS One (2010) 0.99
Assessing rod, cone, and melanopsin contributions to human pupil flicker responses. Invest Ophthalmol Vis Sci (2014) 0.99
The CRTC1-SIK1 pathway regulates entrainment of the circadian clock. Cell (2013) 0.97
Light-dependent phosphorylation of the carboxy tail of mouse melanopsin. Cell Mol Life Sci (2011) 0.97
Phototransduction by retinal ganglion cells that set the circadian clock. Science (2002) 10.42
Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science (2002) 9.08
Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice. Science (2003) 5.02
Light-independent role of CRY1 and CRY2 in the mammalian circadian clock. Science (1999) 4.43
A novel human opsin in the inner retina. J Neurosci (2000) 4.30
Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science (2002) 4.24
CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity. Cell (1998) 4.22
Light-dependent sequestration of TIMELESS by CRYPTOCHROME. Science (1999) 4.09
Characterization of an ocular photopigment capable of driving pupillary constriction in mice. Nat Neurosci (2001) 4.04
Melanopsin: An opsin in melanophores, brain, and eye. Proc Natl Acad Sci U S A (1998) 3.85
Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunit. Proc Natl Acad Sci U S A (2000) 3.72
Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science (1999) 3.41
Role of melanopsin in circadian responses to light. Science (2002) 3.12
Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci (2001) 2.79
Photoreceptive net in the mammalian retina. This mesh of cells may explain how some blind mice can still tell day from night. Nature (2002) 2.67
Masking: history, definitions, and measurement. Chronobiol Int (1999) 2.62
Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc Natl Acad Sci U S A (1999) 2.46
Early receptor potential: photoreversible charge displacement in rhodopsin. Science (1967) 2.17
The photopigment melanopsin is exclusively present in pituitary adenylate cyclase-activating polypeptide-containing retinal ganglion cells of the retinohypothalamic tract. J Neurosci (2002) 2.06
Reduced pupillary light responses in mice lacking cryptochromes. Science (2003) 1.72
Circadian rhythms in mice can be regulated by photoreceptors with cone-like characteristics. Brain Res (1995) 1.60
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice. Proc Natl Acad Sci U S A (2000) 1.50
Masking of locomotor activity in hamsters. J Comp Physiol A (1999) 1.47
Intracellularly recorded early receptor potential of the vertebrate photoreceptors. Vision Res (1970) 1.42
Spectral sensitivity of photoreceptors mediating phase-shifts of circadian rhythms in retinally degenerate CBA/J (rd/rd) and normal CBA/N (+/+)mice. J Comp Physiol A (1996) 1.40
Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and suppression of current in cones from the zebrafish mutant nof. J Neurosci (2003) 1.33
Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice. J Neurosci (2002) 1.30
Nomenclature for ion channel subunits. Science (2001) 1.26
Persistence of masking responses to light in mice lacking rods and cones. J Biol Rhythms (2001) 1.26
Further characterization of the phenotype of mCry1/mCry2-deficient mice. Chronobiol Int (2001) 1.04
Non-visual ocular photoreception. Ophthalmic Genet (2001) 0.96
Retinal repair by transplantation of photoreceptor precursors. Nature (2006) 6.73
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature (1988) 6.12
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science (1991) 5.82
Transplanted suprachiasmatic nucleus determines circadian period. Science (1990) 5.55
Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice. Science (2003) 5.02
A family of hyperpolarization-activated mammalian cation channels. Nature (1998) 4.97
Intensive versus standard case management for severe psychotic illness: a randomised trial. UK 700 Group. Lancet (1999) 4.54
Vibrio parahaemolyticus infections in the United States, 1973-1998. J Infect Dis (2000) 4.35
The naming of voltage-gated calcium channels. Neuron (1994) 4.31
Characterization of an ocular photopigment capable of driving pupillary constriction in mice. Nat Neurosci (2001) 4.04
Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors. Science (1999) 3.96
Restoration of vision after transplantation of photoreceptors. Nature (2012) 3.91
Primary structure and functional expression from complementary DNA of a brain calcium channel. Nature (1991) 3.77
Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunit. Proc Natl Acad Sci U S A (2000) 3.72
Handheld cellular telephone use and risk of brain cancer. JAMA (2000) 3.59
Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science (1999) 3.41
National surveillance of antimicrobial resistance in Neisseria gonorrhoeae. The Gonococcal Isolate Surveillance Project. JAMA (1990) 3.25
Nomenclature of voltage-gated sodium channels. Neuron (2000) 3.10
Nomenclature of voltage-gated calcium channels. Neuron (2000) 3.09
Enteroaggregative Escherichia coli as a major etiologic agent in traveler's diarrhea in 3 regions of the world. Clin Infect Dis (2001) 3.08
Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science (1996) 3.01
The roles of the subunits in the function of the calcium channel. Science (1991) 2.97
Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proc Natl Acad Sci U S A (2004) 2.97
Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J (1998) 2.96
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice. Nat Cell Biol (2001) 2.94
On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch (1985) 2.93
Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis. N Engl J Med (1992) 2.86
Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med (1983) 2.78
Discrepancies in tuberculin skin test results with two commercial products in a population of intravenous drug users. J Infect Dis (1993) 2.77
Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O. Proc Natl Acad Sci U S A (2001) 2.67
Molecular basis for Ca2+ channel diversity. Annu Rev Neurosci (1994) 2.65
Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor. J Immunol (1992) 2.64
Addition of human melanopsin renders mammalian cells photoresponsive. Nature (2005) 2.63
pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos. Cell (1995) 2.61
Two pacemaker channels from human heart with profoundly different activation kinetics. EMBO J (1999) 2.51
Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues. Eur J Biochem (2001) 2.47
The role of Gulf Coast oysters harvested in warmer months in Vibrio vulnificus infections in the United States, 1988-1996. Vibrio Working Group. J Infect Dis (1998) 2.46
Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc Natl Acad Sci U S A (1999) 2.46
New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis. Nat Genet (2001) 2.44
Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel. Nature (1986) 2.41
Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization. Am J Pathol (2000) 2.41
Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle. Science (1989) 2.40
Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice. J Physiol (2002) 2.39
Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current. Nature (1982) 2.33
Costs and cost effectiveness of cardiovascular screening and intervention: the British family heart study. BMJ (1996) 2.27
Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflugers Arch (1986) 2.26
Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta. Nature (2000) 2.17
Randomised controlled trial of treatment of chronic suppurative otitis media in Kenyan schoolchildren. Lancet (1996) 2.16
Randomized controlled trial of brief cognitive behaviour therapy versus treatment as usual in recurrent deliberate self-harm: the POPMACT study. Psychol Med (2003) 2.16
HCN channels: structure, cellular regulation and physiological function. Cell Mol Life Sci (2009) 2.15
Production of cloned pigs from in vitro systems. Nat Biotechnol (2000) 2.15
Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron (2000) 2.13
Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse. J Biol Chem (2000) 2.09
Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature (1991) 2.09
The response of symptomatic neurosyphilis to high-dose intravenous penicillin G in patients with human immunodeficiency virus infection. N Engl J Med (1994) 2.08
Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. FEBS Lett (1990) 2.08
A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins. J Biol Chem (1998) 2.08
Frequency-Dependent Selection for Plasmid-Containing Cells of ESCHERICHIA COLI. Genetics (1979) 2.07
Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells. EMBO J (1995) 2.06
Regional expression and cellular localization of the alpha1 and beta subunit of high voltage-activated calcium channels in rat brain. J Neurosci (1997) 2.05
A dual-radioisotope technique for the evaluation of penile blood flow during tumescence. J Nucl Med (1992) 2.04
Membrane protein diffusion sets the speed of rod phototransduction. Nature (2001) 2.03
Comparison of adenosine 3':5'-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle. J Biol Chem (1975) 2.03
The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins. Mol Cell Biol (1994) 2.03
Perioperative corticosteroid supplementation and dento-alveolar surgery. Dent Update (2003) 2.02
Temporally controlled somatic mutagenesis in smooth muscle. Genesis (2000) 2.01
The relationship between opsin overexpression and photoreceptor degeneration. Invest Ophthalmol Vis Sci (2001) 1.98
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol (1985) 1.92
Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. EMBO J (1992) 1.92
Decline in prevalence of neural tube defects in a high-risk region of the United States. Pediatrics (2000) 1.85
The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast. EMBO J (1998) 1.83
Differential distribution of four hyperpolarization-activated cation channels in mouse brain. Biol Chem (1999) 1.82
Cardiovascular risk factors for people with mental illness. Aust N Z J Psychiatry (2001) 1.81
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochem Pharmacol (1994) 1.76
Twilight times: light and the circadian system. Photochem Photobiol (1997) 1.76
Aminopyridine block of transient potassium current. J Gen Physiol (1982) 1.73
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel. J Clin Invest (1991) 1.71
Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina. Curr Biol (2005) 1.69
Mutant rhodopsin transgene expression on a null background. Invest Ophthalmol Vis Sci (2001) 1.68
Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues. J Biol Chem (1977) 1.67
Transmission of hepatitis C virus from a patient to an anesthesiology assistant to five patients. N Engl J Med (2000) 1.67
Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo. J Bone Miner Res (1997) 1.63