Harmit S Malik

Author PubWeight™ 81.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci U S A 2005 6.85
2 Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. PLoS Biol 2004 4.76
3 Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. PLoS Genet 2009 3.60
4 Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses. Cell 2012 2.94
5 Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host Microbe 2008 2.85
6 The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe 2012 2.79
7 Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. J Virol 2006 2.40
8 The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions. Genome Res 2009 2.35
9 Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9. RNA 2003 2.23
10 Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature 2008 2.13
11 Paleovirology--modern consequences of ancient viruses. PLoS Biol 2010 1.97
12 Rules of engagement: molecular insights from host-virus arms races. Annu Rev Genet 2012 1.92
13 The evolutionary conundrum of pathogen mimicry. Nat Rev Microbiol 2009 1.87
14 Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol 2008 1.86
15 High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Curr Biol 2006 1.85
16 A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin 2012 1.82
17 Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science 2007 1.76
18 Centromeres: selfish drivers. Nature 2002 1.63
19 Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses. J Virol 2010 1.61
20 Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PLoS Pathog 2007 1.60
21 Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species. Science 2009 1.58
22 Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila. PLoS Genet 2005 1.57
23 Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. PLoS Genet 2008 1.52
24 Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J Exp Med 2012 1.48
25 Multiple roles for heterochromatin protein 1 genes in Drosophila. Annu Rev Genet 2009 1.41
26 Paleovirology - ghosts and gifts of viruses past. Curr Opin Virol 2011 1.37
27 Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA. Cell Host Microbe 2012 1.29
28 Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis. Proc Natl Acad Sci U S A 2006 1.26
29 Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes. Proc Natl Acad Sci U S A 2013 1.24
30 Convergent evolution of escape from hepaciviral antagonism in primates. PLoS Biol 2012 1.22
31 Ancient lineages of non-LTR retrotransposons in the primitive eukaryote, Giardia lamblia. Mol Biol Evol 2002 1.21
32 Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila. Proc Natl Acad Sci U S A 2007 1.14
33 Stepwise evolution of essential centromere function in a Drosophila neogene. Science 2013 1.13
34 An expanded clade of rodent Trim5 genes. Virology 2009 1.10
35 The CNA1 histone of the ciliate Tetrahymena thermophila is essential for chromosome segregation in the germline micronucleus. Mol Biol Cell 2005 1.05
36 The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection. J Virol 2011 1.04
37 An evolutionary perspective on the broad antiviral specificity of MxA. Curr Opin Microbiol 2013 1.02
38 Host gene evolution traces the evolutionary history of ancient primate lentiviruses. Philos Trans R Soc Lond B Biol Sci 2013 0.95
39 Phylogenomic analysis reveals dynamic evolutionary history of the Drosophila heterochromatin protein 1 (HP1) gene family. PLoS Genet 2012 0.91
40 Birth, death, and replacement of karyopherins in Drosophila. Mol Biol Evol 2011 0.84
41 The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses. Retrovirology 2012 0.83
42 Absence of positive selection on centromeric histones in Tetrahymena suggests unsuppressed centromere: drive in lineages lacking male meiosis. J Mol Evol 2011 0.83
43 An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family. Genome Biol Evol 2013 0.79
44 A surrogate approach to study the evolution of noncoding DNA elements that organize eukaryotic genomes. J Hered 2009 0.79
45 A rapidly evolving genomic toolkit for Drosophila heterochromatin. Fly (Austin) 2013 0.79
46 Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces. BMC Evol Biol 2010 0.77
47 Molecular evolution of Drosophila Cdc6, an essential DNA replication-licensing gene, suggests an adaptive choice of replication origins. Fly (Austin) 2008 0.76
48 Learning to protect your genome on the fly. Cell 2011 0.76
49 Diamonds and rust: how transposable elements influence mammalian genomes. Conference on Mobile Elements in Mammalian Genomes. EMBO Rep 2009 0.75
50 Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev 2017 0.75