Published in Cell on August 17, 2012
Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response. PLoS Biol (2014) 1.53
Wolbachia variants induce differential protection to viruses in Drosophila melanogaster: a phenotypic and phylogenomic analysis. PLoS Genet (2013) 1.51
An increasing danger of zoonotic orthopoxvirus infections. PLoS Pathog (2013) 1.38
Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins. Proc Natl Acad Sci U S A (2013) 1.34
Poxviruses and the evolution of host range and virulence. Infect Genet Evol (2013) 1.16
When parasitic wasps hijacked viruses: genomic and functional evolution of polydnaviruses. Philos Trans R Soc Lond B Biol Sci (2013) 1.10
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation. PLoS Pathog (2014) 1.08
Mutualism breakdown by amplification of Wolbachia genes. PLoS Biol (2015) 1.02
High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive recombination. J Virol (2015) 0.98
Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread. J Virol (2013) 0.96
Adaptive gene amplification as an intermediate step in the expansion of virus host range. PLoS Pathog (2014) 0.95
The expanding implications of polyploidy. J Cell Biol (2015) 0.95
Single-Cell Analysis of RNA Virus Infection Identifies Multiple Genetically Diverse Viral Genomes within Single Infectious Units. Cell Host Microbe (2015) 0.95
Genetic screen of a mutant poxvirus library identifies an ankyrin repeat protein involved in blocking induction of avian type I interferon. J Virol (2013) 0.94
The external domains of the HIV-1 envelope are a mutational cold spot. Nat Commun (2015) 0.89
A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus. PLoS Pathog (2013) 0.88
An essential cell cycle regulation gene causes hybrid inviability in Drosophila. Science (2015) 0.87
Plasmid copy number underlies adaptive mutability in bacteria. Genetics (2014) 0.86
Double-stranded RNA binding by the human cytomegalovirus PKR antagonist TRS1. Virology (2013) 0.85
Mechanisms of viral mutation. Cell Mol Life Sci (2016) 0.85
Genome scale patterns of recombination between coinfecting vaccinia viruses. J Virol (2014) 0.85
A novel evolutionary strategy revealed in the phaeoviruses. PLoS One (2014) 0.85
Vaccinia virus protein A49 is an unexpected member of the B-cell Lymphoma (Bcl)-2 protein family. J Biol Chem (2015) 0.83
Recent host-shifts in ranaviruses: signatures of positive selection in the viral genome. J Gen Virol (2013) 0.82
Adaptive regulation of testis gene expression and control of male fertility by the Drosophila hairpin RNA pathway. [Corrected]. Mol Cell (2014) 0.82
Fluorescent Protein Approaches in Alpha Herpesvirus Research. Viruses (2015) 0.82
Essential role of protein kinase R antagonism by TRS1 in human cytomegalovirus replication. Virology (2015) 0.81
The genome of the nucleopolyhedrosis-causing virus from Tipula oleracea sheds new light on the Nudiviridae family. J Virol (2014) 0.81
Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo. Emerg Infect Dis (2014) 0.80
Duplication of the A17L locus of vaccinia virus provides an alternate route to rifampin resistance. J Virol (2014) 0.80
Wham: Identifying Structural Variants of Biological Consequence. PLoS Comput Biol (2015) 0.80
Establishment of a Zebrafish Infection Model for the Study of Wild-Type and Recombinant European Sheatfish Virus. J Virol (2015) 0.80
Gene acquisition convergence between entomopoxviruses and baculoviruses. Viruses (2015) 0.80
Genomic comparison of closely related Giant Viruses supports an accordion-like model of evolution. Front Microbiol (2015) 0.80
Pathways of genetic adaptation: multistep origin of mutants under selection without induced mutagenesis in Salmonella enterica. Genetics (2012) 0.79
Identification of nucleotide-level changes impacting gene content and genome evolution in orthopoxviruses. J Virol (2014) 0.79
The complete genome sequences of poxviruses isolated from a penguin and a pigeon in South Africa and comparison to other sequenced avipoxviruses. BMC Genomics (2014) 0.79
Highly heterogeneous mutation rates in the hepatitis C virus genome. Nat Microbiol (2016) 0.79
Functional Segregation of Overlapping Genes in HIV. Cell (2016) 0.78
Experimental Evolution Identifies Vaccinia Virus Mutations in A24R and A35R That Antagonize the Protein Kinase R Pathway and Accompany Collapse of an Extragenic Gene Amplification. J Virol (2015) 0.78
Recombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses. J Virol (2014) 0.78
The Strange Lifestyle of Multipartite Viruses. PLoS Pathog (2016) 0.78
Genetic conflicts: the usual suspects and beyond. J Exp Biol (2017) 0.77
Standing on the Shoulders of Giant Viruses: Five Lessons Learned about Large Viruses Infecting Small Eukaryotes and the Opportunities They Create. PLoS Pathog (2016) 0.77
Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling. Viruses (2015) 0.77
Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily. Viruses (2015) 0.77
Poxvirus use a "gene accordion" to tune out host defenses. Cell (2012) 0.77
Attenuated and replication-competent vaccinia virus strains M65 and M101 with distinct biology and immunogenicity as potential vaccine candidates against pathogens. J Virol (2013) 0.76
Experimental evolution of pathogenesis: "patient" research. PLoS Pathog (2013) 0.76
Emergence of a viral RNA polymerase variant during gene copy number amplification promotes rapid evolution of vaccinia virus. J Virol (2016) 0.75
Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation. Elife (2017) 0.75
A Student's Guide to Giant Viruses Infecting Small Eukaryotes: From Acanthamoeba to Zooxanthellae. Viruses (2017) 0.75
An Evolutionary View of the Arms Race between Protein Kinase R and Large DNA Viruses. J Virol (2016) 0.75
Live-Cell Imaging of Vaccinia Virus Recombination. PLoS Pathog (2016) 0.75
Evolutionary Thrift: Mycobacteria Repurpose Plasmid Diversity during Adaptation of Type VII Secretion Systems. Genome Biol Evol (2017) 0.75
Constrained evolvability of interferon suppression in an RNA virus. Sci Rep (2016) 0.75
Evolutionary clash between myxoma virus and rabbit PKR in Australia. Proc Natl Acad Sci U S A (2016) 0.75
Viral evolution: Accordion adaptations go viral. Nat Rev Microbiol (2012) 0.75
Genome variability and gene content in chordopoxviruses: dependence on microsatellites. Viruses (2015) 0.75
A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists. PLoS Pathog (2016) 0.75
Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate. Genetics (2016) 0.75
Promoter Motifs in NCLDVs: An Evolutionary Perspective. Viruses (2017) 0.75
Species specificity of vaccinia virus complement control protein towards bovine classical pathway is governed primarily by direct interaction of its acidic residues with factor I. J Virol (2017) 0.75
Gene duplication in Pseudomonas aeruginosa improves growth on adenosine. J Bacteriol (2017) 0.75
Rapid Generation of Multiple Loci-Engineered Marker-free Poxvirus and Characterization of a Clinical-Grade Oncolytic Vaccinia Virus. Mol Ther Methods Clin Dev (2017) 0.75
Reverse engineering field isolates of myxoma virus demonstrates that some gene disruptions or loss of function do not explain virulence changes observed in the field. J Virol (2017) 0.75
Heterogeneity of the Epstein-Barr virus major internal repeat reveals evolutionary mechanisms of EBV and a functional defect in the prototype EBV strain B95-8. J Virol (2017) 0.75
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
Rates of spontaneous mutation. Genetics (1998) 14.89
The origin of mutants. Nature (1988) 8.92
Arms races between and within species. Proc R Soc Lond B Biol Sci (1979) 8.54
The complete DNA sequence of vaccinia virus. Virology (1990) 7.76
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature (2005) 6.78
Mutation rates among RNA viruses. Proc Natl Acad Sci U S A (1999) 6.37
Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition. Genome Biol (2010) 6.07
A genome-wide view of the spectrum of spontaneous mutations in yeast. Proc Natl Acad Sci U S A (2008) 5.90
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. J Virol (2006) 5.48
RNA virus error catastrophe: direct molecular test by using ribavirin. Proc Natl Acad Sci U S A (2001) 5.21
Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2002) 4.97
Different trajectories of parallel evolution during viral adaptation. Science (1999) 4.94
Evolution of the mutation rate. Trends Genet (2010) 4.83
Infectious poxvirus vectors have capacity for at least 25 000 base pairs of foreign DNA. Gene (1983) 3.94
Experimental evolution of bet hedging. Nature (2009) 3.92
Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice. PLoS Pathog (2005) 3.41
Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J Virol (1999) 3.13
Ohno's dilemma: evolution of new genes under continuous selection. Proc Natl Acad Sci U S A (2007) 3.10
Repeatability and contingency in the evolution of a key innovation in phage lambda. Science (2012) 2.95
The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms. J Virol (1993) 2.58
Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene. J Virol (1995) 2.55
Population dynamics of a Lac- strain of Escherichia coli during selection for lactose utilization. Genetics (1994) 2.42
Evidence that gene amplification underlies adaptive mutability of the bacterial lac operon. Science (1998) 2.39
The genome of fowlpox virus. J Virol (2000) 2.30
The preparation of orthopoxvirus DNA. J Virol Methods (1981) 2.28
Adaptive amplification: an inducible chromosomal instability mechanism. Cell (2000) 2.17
Amplification-mutagenesis: evidence that "directed" adaptive mutation and general hypermutability result from growth with a selected gene amplification. Proc Natl Acad Sci U S A (2002) 2.15
Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature (2008) 2.13
Adaptive copy number evolution in malaria parasites. PLoS Genet (2008) 2.04
Paleovirology--modern consequences of ancient viruses. PLoS Biol (2010) 1.97
Extensive gene gain associated with adaptive evolution of poxviruses. Proc Natl Acad Sci U S A (2003) 1.90
The evolutionary conundrum of pathogen mimicry. Nat Rev Microbiol (2009) 1.87
Genome sequence diversity and clues to the evolution of variola (smallpox) virus. Science (2006) 1.84
On the origin of smallpox: correlating variola phylogenics with historical smallpox records. Proc Natl Acad Sci U S A (2007) 1.84
Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications. Virus Res (2005) 1.81
The role of the PKR-inhibitory genes, E3L and K3L, in determining vaccinia virus host range. Virology (2002) 1.76
Discovery of antivirals against smallpox. Proc Natl Acad Sci U S A (2004) 1.76
Bacterial gene amplification: implications for the evolution of antibiotic resistance. Nat Rev Microbiol (2009) 1.73
Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha. Mol Cell Biol (1997) 1.67
On the role of ATP in phosphodiester bond hydrolysis catalyzed by the recBC deoxyribonuclease of Escherichia coli. J Biol Chem (1977) 1.66
The life and death of gene families. Bioessays (2009) 1.66
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. Proc Natl Acad Sci U S A (1997) 1.58
Evolution of mutational robustness in an RNA virus. PLoS Biol (2005) 1.54
Two-stepping through time: mammals and viruses. Trends Microbiol (2011) 1.54
Double-stranded RNA binding by human cytomegalovirus pTRS1. J Virol (2005) 1.44
Instability and reiteration of DNA sequences within the vaccinia virus genome. Proc Natl Acad Sci U S A (1981) 1.42
Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. Nat Struct Mol Biol (2008) 1.38
Genomic sequence of chorioallantois vaccinia virus Ankara, the ancestor of modified vaccinia virus Ankara. J Gen Virol (2007) 1.29
High spontaneous rate of gene duplication in Caenorhabditis elegans. Curr Biol (2011) 1.27
Methotrexate resistance and gene amplification. Mechanisms and implications. Cancer (1986) 1.25
Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium. Genetics (2009) 1.25
Poxvirus host range genes. Adv Virus Res (2008) 1.23
Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approach. BMC Evol Biol (2008) 1.18
X-ray crystal structure and functional analysis of vaccinia virus K3L reveals molecular determinants for PKR subversion and substrate recognition. Mol Cell (2002) 1.18
Industrial fuel ethanol yeasts contain adaptive copy number changes in genes involved in vitamin B1 and B6 biosynthesis. Genome Res (2009) 1.12
How vaccinia virus has evolved to subvert the host immune response. J Struct Biol (2011) 1.11
The tandem inversion duplication in Salmonella enterica: selection drives unstable precursors to final mutation types. Genetics (2010) 1.08
Amplification of the ribonucleotide reductase small subunit gene: analysis of novel joints and the mechanism of gene duplication in vaccinia virus. Nucleic Acids Res (1989) 1.00
Hydroxyurea-resistant vaccinia virus: overproduction of ribonucleotide reductase. J Virol (1986) 0.98
Orthopoxvirus genome evolution: the role of gene loss. Viruses (2010) 0.98
Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation. Mol Microbiol (2010) 0.93
The initiation and control of homologous recombination in Escherichia coli. Philos Trans R Soc Lond B Biol Sci (1995) 0.92
Molecular and serological analysis of the epidemiology of myxoma virus in rabbits. Vet Microbiol (2009) 0.90
Targeted capture and massively parallel sequencing of 12 human exomes. Nature (2009) 33.96
Exome sequencing identifies the cause of a mendelian disorder. Nat Genet (2009) 32.06
Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science (2010) 18.45
Multiplex amplification of large sets of human exons. Nat Methods (2007) 15.11
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature (2012) 14.76
Exome sequencing as a tool for Mendelian disease gene discovery. Nat Rev Genet (2011) 14.29
Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nat Genet (2010) 12.63
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. Nat Genet (2011) 11.94
Personalized copy number and segmental duplication maps using next-generation sequencing. Nat Genet (2009) 11.73
Diversity of human copy number variation and multicopy genes. Science (2010) 8.97
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants. Nature (2012) 8.91
Target-enrichment strategies for next-generation sequencing. Nat Methods (2010) 8.78
A high-coverage genome sequence from an archaic Denisovan individual. Science (2012) 7.89
A three-dimensional model of the yeast genome. Nature (2010) 7.01
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci U S A (2005) 6.85
Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. Nat Rev Genet (2011) 6.52
Massively parallel exon capture and library-free resequencing across 16 genomes. Nat Methods (2009) 6.36
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders. Science (2012) 6.21
Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition. Genome Biol (2010) 6.07
Haplotype-resolved genome sequencing of a Gujarati Indian individual. Nat Biotechnol (2010) 5.32
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet (2012) 5.28
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. PLoS Biol (2004) 4.76
Massively parallel functional dissection of mammalian enhancers in vivo. Nat Biotechnol (2012) 4.51
Single-nucleotide evolutionary constraint scores highlight disease-causing mutations. Nat Methods (2010) 4.51
De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes. Nat Genet (2012) 4.51
The beginning of the end for microarrays? Nat Methods (2008) 4.19
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species. Gigascience (2013) 4.11
Noninvasive whole-genome sequencing of a human fetus. Sci Transl Med (2012) 3.94
Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1. Nat Genet (2013) 3.64
Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. PLoS Genet (2009) 3.60
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis. Nat Biotechnol (2009) 3.58
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers. Proc Natl Acad Sci U S A (2011) 3.54
Copy-number variation and false positive prenatal aneuploidy screening results. N Engl J Med (2015) 3.30
Massively parallel sequencing and rare disease. Hum Mol Genet (2010) 3.28
Somatic mutations in cerebral cortical malformations. N Engl J Med (2014) 3.13
Parallel, tag-directed assembly of locally derived short sequence reads. Nat Methods (2010) 3.05
Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res (2010) 2.87
Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host Microbe (2008) 2.85
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe (2012) 2.79
Digital genotyping and haplotyping with polymerase colonies. Proc Natl Acad Sci U S A (2003) 2.77
Fluorescent in situ sequencing on polymerase colonies. Anal Biochem (2003) 2.70
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line. Nature (2013) 2.65
A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome. Nat Genet (2013) 2.59
Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting. Mol Cell (2012) 2.54
Identification of foreign gene sequences by transcript filtering against the human genome. Nat Genet (2002) 2.52
TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome. Nat Genet (2012) 2.50
Estimating the human mutation rate using autozygosity in a founder population. Nat Genet (2012) 2.44
Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. J Virol (2006) 2.40
The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions. Genome Res (2009) 2.35
GABRA1 and STXBP1: novel genetic causes of Dravet syndrome. Neurology (2014) 2.30
Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation. Genome Res (2013) 2.29
Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9. RNA (2003) 2.23
The million mutation project: a new approach to genetics in Caenorhabditis elegans. Genome Res (2013) 2.20
Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia. Hum Mol Genet (2010) 2.19
Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature (2008) 2.13
Genome-scale identification of resistance functions in Pseudomonas aeruginosa using Tn-seq. MBio (2011) 2.13
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell (2007) 2.12
Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster. Nat Genet (2011) 2.07
Characterization of apparently balanced chromosomal rearrangements from the developmental genome anatomy project. Am J Hum Genet (2008) 2.06
Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions. Nat Biotechnol (2013) 2.05
Paleovirology--modern consequences of ancient viruses. PLoS Biol (2010) 1.97
Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1. J Virol (2004) 1.96
Exome sequencing identifies SMAD3 mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms. Circ Res (2011) 1.93
Methods for genomic partitioning. Annu Rev Genomics Hum Genet (2009) 1.93
Rules of engagement: molecular insights from host-virus arms races. Annu Rev Genet (2012) 1.92
The evolutionary conundrum of pathogen mimicry. Nat Rev Microbiol (2009) 1.87
Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol (2008) 1.86
High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Curr Biol (2006) 1.85
GRIN2A mutations cause epilepsy-aphasia spectrum disorders. Nat Genet (2013) 1.85
Cytomegalovirus: pathogen, paradigm, and puzzle. J Clin Invest (2011) 1.82
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science (2007) 1.76
De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome. Nat Genet (2012) 1.70
Long-range polony haplotyping of individual human chromosome molecules. Nat Genet (2006) 1.69
Mutation discovery in mice by whole exome sequencing. Genome Biol (2011) 1.69
Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia. Am J Hum Genet (2012) 1.65
Haploinsufficiency of SF3B4, a component of the pre-mRNA spliceosomal complex, causes Nager syndrome. Am J Hum Genet (2012) 1.63
Centromeres: selfish drivers. Nature (2002) 1.63
Mammalian X upregulation is associated with enhanced transcription initiation, RNA half-life, and MOF-mediated H4K16 acetylation. Dev Cell (2013) 1.61
Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses. J Virol (2010) 1.61
Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PLoS Pathog (2007) 1.60
Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species. Science (2009) 1.58
Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila. PLoS Genet (2005) 1.57
Discovering functional transcription-factor combinations in the human cell cycle. Genome Res (2005) 1.53
Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia. Am J Hum Genet (2012) 1.53
Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. PLoS Genet (2008) 1.52
Exome sequencing in suspected monogenic dyslipidemias. Circ Cardiovasc Genet (2015) 1.51
Ultra-low-input, tagmentation-based whole-genome bisulfite sequencing. Genome Res (2012) 1.50
Binding and nuclear relocalization of protein kinase R by human cytomegalovirus TRS1. J Virol (2006) 1.50
Single molecule profiling of alternative pre-mRNA splicing. Science (2003) 1.48
Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J Exp Med (2012) 1.48
Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee. Genome Res (2011) 1.47