Published in J Gen Physiol on March 01, 2010
Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel. J Biol Chem (2011) 1.00
Interaction of the complexin accessory helix with the C-terminus of the SNARE complex: molecular-dynamics model of the fusion clamp. Biophys J (2013) 0.95
Timothy mutation disrupts the link between activation and inactivation in Ca(V)1.2 protein. J Biol Chem (2011) 0.93
Possible roles of exceptionally conserved residues around the selectivity filters of sodium and calcium channels. J Biol Chem (2010) 0.90
State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels. Pflugers Arch (2014) 0.80
A molecular model of the inner pore of the Ca channel in its open state. Channels (Austin) (2011) 0.76
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Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circ Res (2007) 1.50
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Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands. Biophys J (2004) 1.40
mu-conotoxin GIIIA interactions with the voltage-gated Na(+) channel predict a clockwise arrangement of the domains. J Gen Physiol (2000) 1.30
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A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block. J Biol Chem (2007) 1.26
Access and binding of local anesthetics in the closed sodium channel. Mol Pharmacol (2008) 1.22
Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides. Biochem J (2009) 1.21
A putative prokaryote voltage-gated Ca(2+) channel with only one 6TM motif per subunit. Biochem Biophys Res Commun (2001) 1.17
Mechanism of local anesthetic drug action on voltage-gated sodium channels. Curr Pharm Des (2005) 1.16
Sodium channels: ionic model of slow inactivation and state-dependent drug binding. Biophys J (2007) 1.10
Functional architecture of the inner pore of a voltage-gated Ca2+ channel. J Gen Physiol (2005) 1.09
Molecular modeling of interactions of dihydropyridines and phenylalkylamines with the inner pore of the L-type Ca2+ channel. Mol Pharmacol (2003) 1.07
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Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. J Physiol (2004) 1.01
Structural model for dihydropyridine binding to L-type calcium channels. J Biol Chem (2009) 1.00
Characterizing the 1,4-dihydropyridines binding interactions in the L-type Ca2+ channel: model construction and docking calculations. J Med Chem (2007) 0.99
Models of the structure and gating mechanisms of the pore domain of the NaChBac ion channel. Biophys J (2008) 0.98
Structural model of the Ca V 1.2 pore. Channels (Austin) (2008) 0.98
Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine. FEBS Lett (2006) 0.94
Structural model for phenylalkylamine binding to L-type calcium channels. J Biol Chem (2009) 0.93
How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis. Mol Pharmacol (2005) 0.91
Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions. BMC Struct Biol (2007) 0.91
Molecular modeling of benzothiazepine binding in the L-type calcium channel. J Biol Chem (2008) 0.89
Ion channels of glutamate receptors: structural modeling. Mol Membr Biol (2007) 0.82
K+ channel modulators for the treatment of neurological disorders and autoimmune diseases. Chem Rev (2008) 1.52
Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel. Proc Natl Acad Sci U S A (2013) 1.44
Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands. Biophys J (2004) 1.40
Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter. Mol Pharmacol (2007) 1.24
Access and binding of local anesthetics in the closed sodium channel. Mol Pharmacol (2008) 1.22
Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides. Biochem J (2009) 1.21
Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function. J Comput Aided Mol Des (2010) 1.15
Sodium channel activators: model of binding inside the pore and a possible mechanism of action. FEBS Lett (2005) 1.15
Architecture and pore block of eukaryotic voltage-gated sodium channels in view of NavAb bacterial sodium channel structure. Mol Pharmacol (2012) 1.14
Sodium channels: ionic model of slow inactivation and state-dependent drug binding. Biophys J (2007) 1.10
Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel. J Biol Chem (2011) 1.00
Theoretical study of interaction of winter flounder antifreeze protein with ice. Protein Sci (2004) 1.00
Structural model for dihydropyridine binding to L-type calcium channels. J Biol Chem (2009) 1.00
In silico activation of KcsA K+ channel by lateral forces applied to the C-termini of inner helices. Biophys J (2004) 0.99
Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine. FEBS Lett (2006) 0.94
Structural model for phenylalkylamine binding to L-type calcium channels. J Biol Chem (2009) 0.93
How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis. Mol Pharmacol (2005) 0.91
Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions. BMC Struct Biol (2007) 0.91
Possible roles of exceptionally conserved residues around the selectivity filters of sodium and calcium channels. J Biol Chem (2010) 0.90
Molecular modeling of benzothiazepine binding in the L-type calcium channel. J Biol Chem (2008) 0.89
Potassium channel block by a tripartite complex of two cationophilic ligands and a potassium ion. Mol Pharmacol (2010) 0.89
Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists. Mol Pharmacol (2003) 0.85
KvAP-based model of the pore region of shaker potassium channel is consistent with cadmium- and ligand-binding experiments. Biophys J (2005) 0.84
Serine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel. Pflugers Arch (2007) 0.84
Irreversible block of cardiac mutant Na+ channels by batrachotoxin. Channels (Austin) (2007) 0.84
Structural modeling of calcium binding in the selectivity filter of the L-type calcium channel. Eur Biophys J (2010) 0.83
Interaction of d-tubocurarine with potassium channels: molecular modeling and ligand binding. Mol Pharmacol (2006) 0.83
Docking of calcium ions in proteins with flexible side chains and deformable backbones. Eur Biophys J (2009) 0.81
Mapping of steroids binding to 17 beta-hydroxysteroid dehydrogenase type 1 using Monte Carlo energy minimization reveals alternative binding modes. Biochemistry (2005) 0.80
Batrachotoxin, pyrethroids, and BTG 502 share overlapping binding sites on insect sodium channels. Mol Pharmacol (2011) 0.80
State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels. Pflugers Arch (2014) 0.80
Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1. J Biol Chem (2010) 0.78
Why does the inner-helix mutation A413C double the stoichiometry of Kv1.3 channel block by emopamil but not by verapamil? Mol Pharmacol (2011) 0.77
Interaction of local anesthetics with the K (+) channel pore domain: KcsA as a model for drug-dependent tetramer stability. Channels (Austin) (2013) 0.77
Interaction of the BKCa channel gating ring with dendrotoxins. Channels (Austin) (2014) 0.76