Published in Curr Biol on February 23, 2010
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Classic selective sweeps were rare in recent human evolution. Science (2011) 4.09
Progress and promise of genome-wide association studies for human complex trait genetics. Genetics (2010) 3.81
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nat Genet (2012) 2.78
Genomics: ENCODE explained. Nature (2012) 2.62
Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution. PLoS Genet (2011) 2.44
Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet (2011) 2.24
The QTN program and the alleles that matter for evolution: all that's gold does not glitter. Evolution (2011) 2.23
Adaptations to climate-mediated selective pressures in humans. PLoS Genet (2011) 2.15
Evolutionary conflicts between viruses and restriction factors shape immunity. Nat Rev Immunol (2012) 2.10
Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. Proc Natl Acad Sci U S A (2010) 1.97
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Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication. Science (2014) 1.96
Adaptation - not by sweeps alone. Nat Rev Genet (2010) 1.85
Genomic signatures of selection at linked sites: unifying the disparity among species. Nat Rev Genet (2013) 1.85
An evolutionary framework for association testing in resequencing studies. PLoS Genet (2010) 1.74
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. Nat Genet (2014) 1.74
Evidence of widespread selection on standing variation in Europe at height-associated SNPs. Nat Genet (2012) 1.71
The effect of variation in the effective population size on the rate of adaptive molecular evolution in eukaryotes. Genome Biol Evol (2012) 1.69
Harnessing genomics for delineating conservation units. Trends Ecol Evol (2012) 1.67
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The genomic signature of parallel adaptation from shared genetic variation. Mol Ecol (2014) 1.58
Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae. Proc Natl Acad Sci U S A (2012) 1.55
Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome. PLoS Genet (2011) 1.54
Shared and unique components of human population structure and genome-wide signals of positive selection in South Asia. Am J Hum Genet (2011) 1.52
Gene expression drives local adaptation in humans. Genome Res (2013) 1.50
Natural selection and infectious disease in human populations. Nat Rev Genet (2014) 1.48
A population genetic signal of polygenic adaptation. PLoS Genet (2014) 1.46
Pervasive adaptive protein evolution apparent in diversity patterns around amino acid substitutions in Drosophila simulans. PLoS Genet (2011) 1.43
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Evolutionary genetics of plant adaptation. Trends Genet (2011) 1.32
Genetic origins of lactase persistence and the spread of pastoralism in Africa. Am J Hum Genet (2014) 1.27
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Proc Natl Acad Sci U S A (2012) 1.26
On detecting incomplete soft or hard selective sweeps using haplotype structure. Mol Biol Evol (2014) 1.25
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Adaptive evolution: evaluating empirical support for theoretical predictions. Nat Rev Genet (2012) 1.22
Robust identification of local adaptation from allele frequencies. Genetics (2013) 1.21
Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes. Am J Hum Genet (2016) 1.18
Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps. PLoS Genet (2015) 1.18
Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? PLoS Genet (2011) 1.17
Human brain evolution: transcripts, metabolites and their regulators. Nat Rev Neurosci (2013) 1.16
Recent human adaptation: genomic approaches, interpretation and insights. Nat Rev Genet (2013) 1.15
Worldwide distribution of the MYH9 kidney disease susceptibility alleles and haplotypes: evidence of historical selection in Africa. PLoS One (2010) 1.14
The population structure and recent colonization history of Oregon threespine stickleback determined using restriction-site associated DNA-sequencing. Mol Ecol (2013) 1.14
Evidence for widespread positive and purifying selection across the European rabbit (Oryctolagus cuniculus) genome. Mol Biol Evol (2012) 1.13
Testing for associations between loci and environmental gradients using latent factor mixed models. Mol Biol Evol (2013) 1.13
The timing of pigmentation lightening in Europeans. Mol Biol Evol (2012) 1.13
The promise and limitations of population exomics for human evolution studies. Genome Biol (2011) 1.13
Selection for complex traits leaves little or no classic signatures of selection. BMC Genomics (2014) 1.13
Molecular hyperdiversity and evolution in very large populations. Mol Ecol (2013) 1.11
Human pigmentation genes under environmental selection. Genome Biol (2012) 1.11
Detecting signatures of selection through haplotype differentiation among hierarchically structured populations. Genetics (2013) 1.10
Common risk alleles for inflammatory diseases are targets of recent positive selection. Am J Hum Genet (2013) 1.09
Explaining additional genetic variation in complex traits. Trends Genet (2014) 1.08
A genome-wide scan for evidence of selection in a maize population under long-term artificial selection for ear number. Genetics (2013) 1.08
Candidate genes and genetic architecture of symbiotic and agronomic traits revealed by whole-genome, sequence-based association genetics in Medicago truncatula. PLoS One (2013) 1.08
Population genetic tools for dissecting innate immunity in humans. Nat Rev Immunol (2013) 1.08
Using genomics to characterize evolutionary potential for conservation of wild populations. Evol Appl (2014) 1.07
Toward a new history and geography of human genes informed by ancient DNA. Trends Genet (2014) 1.07
Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey. PLoS One (2011) 1.07
Genetic diversity and the structure of genealogies in rapidly adapting populations. Genetics (2012) 1.06
Multilocus genetic models of handedness closely resemble single-locus models in explaining family data and are compatible with genome-wide association studies. Ann N Y Acad Sci (2013) 1.05
Limited evidence for classic selective sweeps in African populations. Genetics (2012) 1.04
Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolution. PLoS Genet (2012) 1.03
Population genetic differentiation of height and body mass index across Europe. Nat Genet (2015) 1.03
Disentangling the roles of history and local selection in shaping clinal variation of allele frequencies and gene expression in Norway spruce (Picea abies). Genetics (2012) 1.02
Genome-wide analysis of cold adaptation in indigenous Siberian populations. PLoS One (2014) 1.02
Population Genomics of Human Adaptation. Annu Rev Ecol Evol Syst (2013) 1.01
Synchronous waves of failed soft sweeps in the laboratory: remarkably rampant clonal interference of alleles at a single locus. Genetics (2013) 1.00
Evidence for recent, population-specific evolution of the human mutation rate. Proc Natl Acad Sci U S A (2015) 1.00
Patterns of neutral diversity under general models of selective sweeps. Genetics (2012) 1.00
Strong gene flow and lack of stable population structure in the face of rapid adaptation to local temperature in a spring-spawning salmonid, the European grayling (Thymallus thymallus). Heredity (Edinb) (2011) 0.99
Population genetic analysis of the uncoupling proteins supports a role for UCP3 in human cold resistance. Mol Biol Evol (2010) 0.99
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers. Proc Natl Acad Sci U S A (2014) 0.98
Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biol (2014) 0.98
A novel analytical method, Birth Date Selection Mapping, detects response of the Angus (Bos taurus) genome to selection on complex traits. BMC Genomics (2012) 0.97
Complex trait divergence contributes to environmental niche differentiation in ecological speciation of Boechera stricta. Mol Ecol (2013) 0.96
Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. Mol Ecol (2012) 0.96
Parallel adaptive divergence among geographically diverse human populations. PLoS Genet (2011) 0.96
Biological invasions, climate change and genomics. Evol Appl (2014) 0.95
Genomic signature of adaptation to climate in Medicago truncatula. Genetics (2014) 0.95
Composite selection signals can localize the trait specific genomic regions in multi-breed populations of cattle and sheep. BMC Genet (2014) 0.95
A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait. Am J Hum Genet (2015) 0.94
The Andean adaptive toolkit to counteract high altitude maladaptation: genome-wide and phenotypic analysis of the Collas. PLoS One (2014) 0.94
Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biol (2014) 0.94
Whole-genome sequencing of two North American Drosophila melanogaster populations reveals genetic differentiation and positive selection. Mol Ecol (2013) 0.94
Positive natural selection of TRIB2, a novel gene that influences visceral fat accumulation, in East Asia. Hum Genet (2012) 0.93
Soft shoulders ahead: spurious signatures of soft and partial selective sweeps result from linked hard sweeps. Genetics (2015) 0.92
Widespread signals of convergent adaptation to high altitude in Asia and america. Am J Hum Genet (2014) 0.92
Morphological and population genomic evidence that human faces have evolved to signal individual identity. Nat Commun (2014) 0.91
Population genomics of the Anthropocene: urbanization is negatively associated with genome-wide variation in white-footed mouse populations. Evol Appl (2016) 0.91
Signatures of selection in sheep bred for resistance or susceptibility to gastrointestinal nematodes. BMC Genomics (2014) 0.91
An Expanded View of Complex Traits: From Polygenic to Omnigenic. Cell (2017) 0.91
Adaptations to local environments in modern human populations. Curr Opin Genet Dev (2014) 0.90
Genetic architecture of parallel pelvic reduction in ninespine sticklebacks. G3 (Bethesda) (2013) 0.90
Estimating the strength of selective sweeps from deep population diversity data. Genetics (2012) 0.90
Environmental adaptation contributes to gene polymorphism across the Arabidopsis thaliana genome. Mol Biol Evol (2012) 0.90
Detection of human adaptation during the past 2000 years. Science (2016) 0.89
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The hitch-hiking effect of a favourable gene. Genet Res (1974) 34.74
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
The effect of deleterious mutations on neutral molecular variation. Genetics (1993) 20.07
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Many sequence variants affecting diversity of adult human height. Nat Genet (2008) 12.80
Positive natural selection in the human lineage. Science (2006) 12.55
SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science (2005) 12.02
Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet (2004) 11.90
Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles. Science (2005) 10.46
Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet (2006) 9.44
Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet (2008) 8.92
Genetic determinants of hair, eye and skin pigmentation in Europeans. Nat Genet (2007) 8.79
Signals of recent positive selection in a worldwide sample of human populations. Genome Res (2009) 8.38
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science (2001) 7.87
Identification of a variant associated with adult-type hypolactasia. Nat Genet (2002) 7.49
Natural selection has driven population differentiation in modern humans. Nat Genet (2008) 7.48
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet (2006) 7.13
Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans. Nat Genet (2007) 6.63
Soft sweeps: molecular population genetics of adaptation from standing genetic variation. Genetics (2005) 5.99
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Constructing genomic maps of positive selection in humans: where do we go from here? Genome Res (2009) 5.88
Fundamental concepts in genetics: effective population size and patterns of molecular evolution and variation. Nat Rev Genet (2009) 5.45
Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes. Proc Natl Acad Sci U S A (2005) 5.21
Localizing recent adaptive evolution in the human genome. PLoS Genet (2007) 5.11
Recent and ongoing selection in the human genome. Nat Rev Genet (2007) 4.62
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Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus. Am J Hum Genet (2000) 4.39
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How reliable are empirical genomic scans for selective sweeps? Genome Res (2006) 4.14
The evolution of human skin coloration. J Hum Evol (2000) 4.07
Haldane's sieve and adaptation from the standing genetic variation. Genetics (2001) 4.02
Pervasive hitchhiking at coding and regulatory sites in humans. PLoS Genet (2009) 4.02
Genetic hitchhiking. Philos Trans R Soc Lond B Biol Sci (2000) 3.81
cis-Regulatory changes in Kit ligand expression and parallel evolution of pigmentation in sticklebacks and humans. Cell (2007) 3.72
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The role of geography in human adaptation. PLoS Genet (2009) 3.41
Pervasive natural selection in the Drosophila genome? PLoS Genet (2009) 3.27
Recent acceleration of human adaptive evolution. Proc Natl Acad Sci U S A (2007) 3.13
The evolution of gene regulation underlies a morphological difference between two Drosophila sister species. Cell (2008) 3.10
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Adaptations to climate in candidate genes for common metabolic disorders. PLoS Genet (2008) 2.68
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Genomic insights into positive selection. Trends Genet (2006) 2.53
Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals. Genome Res (2008) 2.46
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture. Am J Hum Genet (2008) 2.28
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Predicting human height by Victorian and genomic methods. Eur J Hum Genet (2009) 1.69
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Adaptations to climate in candidate genes for common metabolic disorders. PLoS Genet (2008) 2.68
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Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. Proc Natl Acad Sci U S A (2010) 1.97
The Capsella rubella genome and the genomic consequences of rapid mating system evolution. Nat Genet (2013) 1.69
Expression quantitative trait loci detected in cell lines are often present in primary tissues. Hum Mol Genet (2009) 1.57
Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet (2009) 1.42
Parallel adaptation: one or many waves of advance of an advantageous allele? Genetics (2010) 1.39
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Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res (2011) 1.36
Back to nature: ecological genomics of loblolly pine (Pinus taeda, Pinaceae). Mol Ecol (2010) 1.35
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Retracted Darwinian selection on a selfing locus. Science (2004) 1.29
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The timing of selection at the human FOXP2 gene. Mol Biol Evol (2008) 1.09
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The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate. PLoS Genet (2010) 0.86
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The Role of Standing Variation in Geographic Convergent Adaptation. Am Nat (2015) 0.80
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Adaptive drool in the gene pool. Nat Genet (2007) 0.79
Misuse of hierarchical linear models overstates the significance of a reported association between OXTR and prosociality. Proc Natl Acad Sci U S A (2012) 0.78
Erratum: Detection and interpretation of shared genetic influences on 42 human traits. Nat Genet (2016) 0.77
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Sperm should evolve to make female meiosis fair. Evolution (2015) 0.75
Retraction. Science (2008) 0.75