Published in RNA on February 25, 2010
The Cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biol (2011) 1.35
Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1). Proc Natl Acad Sci U S A (2010) 1.24
Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5. Nucleic Acids Res (2011) 1.18
Translation in giant viruses: a unique mixture of bacterial and eukaryotic termination schemes. PLoS Genet (2012) 0.89
A bifunctional protein regulates mitochondrial protein synthesis. Nucleic Acids Res (2014) 0.80
A mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes. PLoS One (2013) 0.77
Regulation of release factor expression using a translational negative feedback loop: a systems analysis. RNA (2012) 0.76
mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach. BMC Syst Biol (2014) 0.75
Expression of the eRF1 translation termination factor is controlled by an autoregulatory circuit involving readthrough and nonsense-mediated decay in plants. Nucleic Acids Res (2017) 0.75
A synthetic oscillatory network of transcriptional regulators. Nature (2000) 24.58
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature (2006) 12.92
Engineering stability in gene networks by autoregulation. Nature (2000) 12.88
Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr Opin Cell Biol (2002) 9.17
Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science (2005) 6.88
Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature (2006) 4.89
The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae. EMBO J (1995) 4.68
Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3. EMBO J (1995) 4.66
A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature (1994) 4.21
Bacterial peptide chain release factors: conserved primary structure and possible frameshift regulation of release factor 2. Proc Natl Acad Sci U S A (1985) 3.94
Expression of peptide chain release factor 2 requires high-efficiency frameshift. Nature (1986) 3.60
Reading frame switch caused by base-pair formation between the 3' end of 16S rRNA and the mRNA during elongation of protein synthesis in Escherichia coli. EMBO J (1988) 3.18
Ribosome biogenesis and the translation process in Escherichia coli. Microbiol Mol Biol Rev (2007) 2.59
The identity of the base following the stop codon determines the efficiency of in vivo translational termination in Escherichia coli. EMBO J (1995) 2.36
Sequence analysis suggests that tetra-nucleotides signal the termination of protein synthesis in eukaryotes. Nucleic Acids Res (1990) 2.20
Quality control by the ribosome following peptide bond formation. Nature (2008) 2.15
A posttermination ribosomal complex is the guanine nucleotide exchange factor for peptide release factor RF3. Cell (2001) 2.10
Translation initiation factor 3 antagonizes authentic start codon selection on leaderless mRNAs. Mol Microbiol (1999) 2.04
The accuracy of codon recognition by polypeptide release factors. Proc Natl Acad Sci U S A (2000) 2.03
RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors. Cell (2007) 1.89
GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination. Mol Cell Biol (2004) 1.87
Use of tRNA suppressors to probe regulation of Escherichia coli release factor 2. J Mol Biol (1988) 1.83
Ribosomal protein L32 of Saccharomyces cerevisiae regulates both splicing and translation of its own transcript. J Biol Chem (1993) 1.69
Maintaining the ribosomal reading frame: the influence of the E site during translational regulation of release factor 2. Cell (2004) 1.68
How initiation factors maximize the accuracy of tRNA selection in initiation of bacterial protein synthesis. Mol Cell (2006) 1.58
Release factor-dependent false stops are infrequent in Escherichia coli. J Mol Biol (1993) 1.57
Halting a cellular production line: responses to ribosomal pausing during translation. Biol Cell (2007) 1.55
The role of the AUU initiation codon in the negative feedback regulation of the gene for translation initiation factor IF3 in Escherichia coli. Mol Microbiol (1996) 1.48
Autogenous control of the S10 ribosomal protein operon of Escherichia coli: genetic dissection of transcriptional and posttranscriptional regulation. Proc Natl Acad Sci U S A (1987) 1.48
Autoregulation of poly(A)-binding protein synthesis in vitro. Nucleic Acids Res (1995) 1.47
Escherichia coli protein synthesis initiation factor IF3 controls its own gene expression at the translational level in vivo. J Mol Biol (1986) 1.41
AUU-to-AUG mutation in the initiator codon of the translation initiation factor IF3 abolishes translational autocontrol of its own gene (infC) in vivo. Proc Natl Acad Sci U S A (1987) 1.40
The concentration of polypeptide chain release factors 1 and 2 at different growth rates of Escherichia coli. J Mol Biol (1994) 1.30
Autogenous suppression of an opal mutation in the gene encoding peptide chain release factor 2. Proc Natl Acad Sci U S A (1990) 1.30
Release factor 2 frameshifting sites in different bacteria. EMBO Rep (2002) 1.29
Competition between frameshifting, termination and suppression at the frameshift site in the Escherichia coli release factor-2 mRNA. Nucleic Acids Res (1993) 1.26
Non-canonical mechanism for translational control in bacteria: synthesis of ribosomal protein S1. EMBO J (2001) 1.26
Initiation factors IF1 and IF2 synergistically remove peptidyl-tRNAs with short polypeptides from the P-site of translating Escherichia coli ribosomes. J Mol Biol (1998) 1.25
Escherichia coli translational initiation factor IF3: a unique case of translational regulation. Proc Natl Acad Sci U S A (1984) 1.25
Distinct eRF3 requirements suggest alternate eRF1 conformations mediate peptide release during eukaryotic translation termination. Mol Cell (2008) 1.25
Translational control of poly(A)-binding protein expression. Eur J Biochem (1996) 1.24
Depletion in the levels of the release factor eRF1 causes a reduction in the efficiency of translation termination in yeast. Mol Microbiol (1996) 1.24
Translational autocontrol of the Escherichia coli ribosomal protein S15. J Mol Biol (1990) 1.23
Genetic analysis of the E site during RF2 programmed frameshifting. RNA (2007) 1.23
The translational fidelity function of IF3 during transition from the 30 S initiation complex to the 70 S initiation complex. J Mol Biol (2007) 1.19
Origins of minigene-dependent growth inhibition in bacterial cells. EMBO J (2000) 1.14
Discrimination by Escherichia coli initiation factor IF3 against initiation on non-canonical codons relies on complementarity rules. J Mol Biol (1999) 1.06
Overexpression of poly(A)-binding protein down-regulates the translation or the abundance of its own mRNA. FEBS Lett (1999) 1.03
Translational repression contributes greater noise to gene expression than transcriptional repression. Biophys J (2009) 1.03
Nature of the ribosomal mRNA track: analysis of ribosome-binding sites containing different sequences and secondary structures. Biochemistry (1993) 1.02
Stabilised secondary structure at a ribosomal binding site enhances translational repression in E. coli. J Mol Biol (1995) 0.96
Exceptional codon recognition by the glutamine tRNAs in Saccharomyces cerevisiae. EMBO J (1991) 0.93
Stop codons and UGG promote efficient binding of the polypeptide release factor eRF1 to the ribosomal A site. J Mol Biol (2003) 0.93
IF3-mediated suppression of a GUA initiation codon mutation in the recJ gene of Escherichia coli. J Bacteriol (1997) 0.93
Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae. BMC Mol Biol (2003) 0.91
Is the in-frame termination signal of the Escherichia coli release factor-2 frameshift site weakened by a particularly poor context? Nucleic Acids Res (1996) 0.91
Evidence for a role of initiation factor 3 in recycling of ribosomal complexes stalled on mRNAs in Escherichia coli. Nucleic Acids Res (2005) 0.86
Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae. BMC Mol Biol (2007) 0.83
A mathematical modelling framework for elucidating the role of feedback control in translation termination. J Theor Biol (2010) 0.79
The paradox of viable sup45 STOP mutations: a necessary equilibrium between translational readthrough, activity and stability of the protein. Mol Genet Genomics (2009) 0.78
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
Estimating the size of the human interactome. Proc Natl Acad Sci U S A (2008) 3.66
Mechanism of action and antiviral activity of benzimidazole-based allosteric inhibitors of the hepatitis C virus RNA-dependent RNA polymerase. J Virol (2003) 2.63
tRNA properties help shape codon pair preferences in open reading frames. Nucleic Acids Res (2006) 1.63
Halting a cellular production line: responses to ribosomal pausing during translation. Biol Cell (2007) 1.55
Phylogenetic diversity of stress signalling pathways in fungi. BMC Evol Biol (2009) 1.40
Transmission characteristics of the 2009 H1N1 influenza pandemic: comparison of 8 Southern hemisphere countries. PLoS Pathog (2011) 1.38
Ribosome traffic on mRNAs maps to gene ontology: genome-wide quantification of translation initiation rates and polysome size regulation. PLoS Comput Biol (2013) 1.08
Queueing phase transition: theory of translation. Phys Rev Lett (2009) 1.06
Physiological analysis of the role of truB in Escherichia coli: a role for tRNA modification in extreme temperature resistance. Microbiology (2002) 1.03
Synthesis and SAR of piperazinyl-N-phenylbenzamides as inhibitors of hepatitis C virus RNA replication in cell culture. Bioorg Med Chem Lett (2009) 0.94
A yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation. Mol Microbiol (2012) 0.94
Spliced leader trans-splicing in the nematode Trichinella spiralis uses highly polymorphic, noncanonical spliced leaders. RNA (2008) 0.90
Translational recoding as a feedback controller: systems approaches reveal polyamine-specific effects on the antizyme ribosomal frameshift. Nucleic Acids Res (2011) 0.88
Recombination hotspots as a point process. Philos Trans R Soc Lond B Biol Sci (2005) 0.87
The evolution of spliced leader trans-splicing in nematodes. Biochem Soc Trans (2010) 0.85
Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2. BMC Mol Biol (2007) 0.84
The fluorescent two-hybrid assay to screen for protein-protein interaction inhibitors in live cells: targeting the interaction of p53 with Mdm2 and Mdm4. J Biomol Screen (2014) 0.82
Diastereoselective metal-catalyzed synthesis of C-aryl and C-vinyl glycosides. Angew Chem Int Ed Engl (2012) 0.80
Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett (2006) 0.79
A mathematical modelling framework for elucidating the role of feedback control in translation termination. J Theor Biol (2010) 0.79
SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease. Bioorg Med Chem Lett (2004) 0.79
Regulation of release factor expression using a translational negative feedback loop: a systems analysis. RNA (2012) 0.76
Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation. BMC Syst Biol (2011) 0.76
Cobalt-catalyzed diastereoselective synthesis of C-furanosides. Total synthesis of (-)-isoaltholactone. J Org Chem (2013) 0.75
Synthesis of substituted indenones and indanones by a Suzuki-Miyaura coupling/acid-promoted cyclisation sequence. Org Biomol Chem (2013) 0.75
Two-step one-pot synthesis of benzoannulated spiroacetals by Suzuki-Miyaura coupling/acid-catalyzed spiroacetalization. Org Lett (2012) 0.75
Tandem Suzuki-Miyaura coupling/acid-catalyzed cyclization between vinyl ether boronates and vinyl halides: a concise approach to polysubstituted furans. Org Lett (2013) 0.75
Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease. Bioorg Med Chem Lett (2002) 0.75
Self-directed student research through analysis of microarray datasets: a computer-based functional genomics practical class for masters-level students. Biochem Mol Biol Educ (2011) 0.75