Published in EMBO J on May 01, 1988
Errors and alternatives in reading the universal genetic code. Microbiol Rev (1989) 4.67
Codon preferences in free-living microorganisms. Microbiol Rev (1990) 4.66
The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria. Nature (2012) 4.27
A -1 ribosomal frameshift in a double-stranded RNA virus of yeast forms a gag-pol fusion protein. Proc Natl Acad Sci U S A (1991) 4.08
Programmed translational frameshifting. Microbiol Rev (1996) 3.89
Nonsense-mediated decay mutants do not affect programmed -1 frameshifting. RNA (2000) 3.13
The identity of the base following the stop codon determines the efficiency of in vivo translational termination in Escherichia coli. EMBO J (1995) 2.36
Coding from a distance: dissection of the mRNA determinants required for the incorporation of selenocysteine into protein. EMBO J (1992) 2.29
Translation of the sequence AGG-AGG yields 50% ribosomal frameshift. Proc Natl Acad Sci U S A (1988) 1.99
The second to last amino acid in the nascent peptide as a codon context determinant. EMBO J (1994) 1.98
How translational accuracy influences reading frame maintenance. EMBO J (1999) 1.96
Site-directed cross-linking of mRNA analogues to the Escherichia coli ribosome; identification of 30S ribosomal components that can be cross-linked to the mRNA at various points 5' with respect to the decoding site. Nucleic Acids Res (1989) 1.93
rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift. J Bacteriol (1994) 1.88
Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation. Nucleic Acids Res (2007) 1.55
Analysis of effects of tRNA:message stability on frameshift frequency at the Escherichia coli RF2 programmed frameshift site. Nucleic Acids Res (1993) 1.47
tRNA hopping: enhancement by an expanded anticodon. EMBO J (1989) 1.47
P-site tRNA is a crucial initiator of ribosomal frameshifting. RNA (2004) 1.46
Conditionally lethal and recessive UGA-suppressor mutations in the prfB gene encoding peptide chain release factor 2 of Escherichia coli. J Bacteriol (1988) 1.44
Ribosomal frameshifting requires a pseudoknot in the Saccharomyces cerevisiae double-stranded RNA virus. J Virol (1992) 1.43
Frameshift autoregulation in the gene for Escherichia coli release factor 2: partly functional mutants result in frameshift enhancement. Nucleic Acids Res (1990) 1.41
Codon bias in Escherichia coli: the influence of codon context on mutation and selection. Nucleic Acids Res (1997) 1.36
Autogenous suppression of an opal mutation in the gene encoding peptide chain release factor 2. Proc Natl Acad Sci U S A (1990) 1.30
Increased ribosomal accuracy increases a programmed translational frameshift in Escherichia coli. Proc Natl Acad Sci U S A (1993) 1.30
Salmonella typhimurium prfA mutants defective in release factor 1. J Bacteriol (1991) 1.30
Release factor 2 frameshifting sites in different bacteria. EMBO Rep (2002) 1.29
The subtilin gene of Bacillus subtilis ATCC 6633 is encoded in an operon that contains a homolog of the hemolysin B transport protein. J Bacteriol (1992) 1.27
Competition between frameshifting, termination and suppression at the frameshift site in the Escherichia coli release factor-2 mRNA. Nucleic Acids Res (1993) 1.26
Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit. Nucleic Acids Res (2000) 1.25
mRNA pseudoknot structures can act as ribosomal roadblocks. Nucleic Acids Res (2011) 1.22
Analyses of frameshifting at UUU-pyrimidine sites. Nucleic Acids Res (1997) 1.21
Frameshifting in gene 10 of bacteriophage T7. J Bacteriol (1991) 1.21
An analysis of sequences stimulating frameshifting in the decoding of gene 10 of bacteriophage T7. Nucleic Acids Res (1991) 1.20
Special peptidyl-tRNA molecules can promote translational frameshifting without slippage. Mol Cell Biol (1994) 1.18
Sequence comparison of new prokaryotic and mitochondrial members of the polypeptide chain release factor family predicts a five-domain model for release factor structure. Nucleic Acids Res (1992) 1.15
Intermolecular mRNA-rRNA hybridization and the distribution of potential interaction regions in murine 18S rRNA. Nucleic Acids Res (1993) 1.12
RNase I*, a form of RNase I, and mRNA degradation in Escherichia coli. J Bacteriol (1991) 1.12
The coding and noncoding architecture of the Caulobacter crescentus genome. PLoS Genet (2014) 1.11
endAFS, a novel family E endoglucanase gene from Fibrobacter succinogenes AR1. J Bacteriol (1991) 1.10
Programmed +1 frameshifting stimulated by complementarity between a downstream mRNA sequence and an error-correcting region of rRNA. RNA (2001) 1.09
Maintenance of the correct open reading frame by the ribosome. EMBO Rep (2003) 1.09
Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expression. RNA (2002) 1.08
Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling. Cell Rep (2016) 1.06
Ribosomal -1 frameshifting during decoding of Bacillus subtilis cdd occurs at the sequence CGA AAG. J Bacteriol (1999) 1.05
Mutations in 16S rRNA that affect UGA (stop codon)-directed translation termination. Proc Natl Acad Sci U S A (1991) 1.05
rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments. Bioinformatics (2013) 1.04
Ribosome profiling: a Hi-Def monitor for protein synthesis at the genome-wide scale. Wiley Interdiscip Rev RNA (2013) 1.02
Structural changes in the 530 loop of Escherichia coli 16S rRNA in mutants with impaired translational fidelity. Nucleic Acids Res (1995) 1.01
Restoration of a translational stop-start overlap reinstates translational coupling in a mutant trpB'-trpA gene pair of the Escherichia coli tryptophan operon. Nucleic Acids Res (1989) 1.00
Expression levels influence ribosomal frameshifting at the tandem rare arginine codons AGG_AGG and AGA_AGA in Escherichia coli. J Bacteriol (2005) 1.00
Glycine tRNA mutants with normal anticodon loop size cause -1 frameshifting. Proc Natl Acad Sci U S A (1989) 1.00
Mutations which alter the elbow region of tRNA2Gly reduce T4 gene 60 translational bypassing efficiency. EMBO J (1999) 0.97
A new kinetic model reveals the synergistic effect of E-, P- and A-sites on +1 ribosomal frameshifting. Nucleic Acids Res (2008) 0.97
Programmed translational frameshift in the bacteriophage P2 FETUD tail gene operon. J Bacteriol (2002) 0.97
Ribosomal proteins S7 and L1 are located close to the decoding site of E. coli ribosome--affinity labeling studies with modified tRNAs carrying photoreactive probes attached adjacent to the 3'-end of the anticodon. Nucleic Acids Res (1989) 0.95
Structural requirements for efficient translational frameshifting in the synthesis of the putative viral RNA-dependent RNA polymerase of potato leafroll virus. Nucleic Acids Res (1993) 0.94
Evolution of +1 programmed frameshifting signals and frameshift-regulating tRNAs in the order Saccharomycetales. J Mol Evol (2006) 0.94
Spacer-length dependence of programmed -1 or -2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting. Nucleic Acids Res (2012) 0.94
Is the in-frame termination signal of the Escherichia coli release factor-2 frameshift site weakened by a particularly poor context? Nucleic Acids Res (1996) 0.91
Autoregulatory systems controlling translation factor expression: thermostat-like control of translational accuracy. RNA (2010) 0.90
Short spacing between the Shine-Dalgarno sequence and P codon destabilizes codon-anticodon pairing in the P site to promote +1 programmed frameshifting. Mol Microbiol (2010) 0.88
Augmented genetic decoding: global, local and temporal alterations of decoding processes and codon meaning. Nat Rev Genet (2015) 0.88
Efficient expression of gene variants that harbour AGA codons next to the initiation codon. Nucleic Acids Res (2007) 0.84
Saturation mutagenesis of a +1 programmed frameshift-inducing mRNA sequence derived from a yeast retrotransposon. RNA (2007) 0.84
An mRNA sequence derived from the yeast EST3 gene stimulates programmed +1 translational frameshifting. RNA (2007) 0.83
FSscan: a mechanism-based program to identify +1 ribosomal frameshift hotspots. Nucleic Acids Res (2009) 0.82
Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use. Nucleic Acids Res (2016) 0.82
Translational defects in a mutant deficient in YajL, the bacterial homolog of the parkinsonism-associated protein DJ-1. J Bacteriol (2010) 0.82
Analysis of free energy signals arising from nucleotide hybridization between rRNA and mRNA sequences during translation in eubacteria. EURASIP J Bioinform Syst Biol (2006) 0.81
The Frequency of Internal Shine-Dalgarno-like Motifs in Prokaryotes. Genome Biol Evol (2016) 0.79
A plausible role for the presence of internal shine-dalgarno sites. Bioinform Biol Insights (2010) 0.79
Genetically engineered frameshifted YopN-TyeA chimeras influence type III secretion system function in Yersinia pseudotuberculosis. PLoS One (2013) 0.79
Distinctive patterns of translational reinitiation in the lac repressor mRNA: bridging of long distances by out-of-frame translation and RNA secondary structure, effects of primary sequence. Nucleic Acids Res (1991) 0.79
Mutational analysis of sequences in the recF gene of Escherichia coli K-12 that affect expression. J Bacteriol (1994) 0.78
A general strategy to inhibiting viral -1 frameshifting based on upstream attenuation duplex formation. Nucleic Acids Res (2015) 0.78
Anticodon loop mutations perturb reading frame maintenance by the E site tRNA. RNA (2008) 0.77
Does disparate occurrence of autoregulatory programmed frameshifting in decoding the release factor 2 gene reflect an ancient origin with loss in independent lineages? J Bacteriol (1998) 0.77
A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA. J Biol Chem (2015) 0.77
YopN and TyeA Hydrophobic Contacts Required for Regulating Ysc-Yop Type III Secretion Activity by Yersinia pseudotuberculosis. Front Cell Infect Microbiol (2016) 0.75
Quantitative analysis of in vivo ribosomal events at UGA and UAG stop codons. Nucleic Acids Res (1998) 0.75
Identification of protein-coding sequences using the hybridization of 18S rRNA and mRNA during translation. Nucleic Acids Res (2008) 0.75
Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. DNA (1985) 40.01
How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli. Proc Natl Acad Sci U S A (1975) 10.60
Versatile low-copy-number plasmid vectors for cloning in Escherichia coli. Gene (1982) 6.62
Improved plasmid vectors with a thermoinducible expression and temperature-regulated runaway replication. Gene (1983) 4.87
Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol. J Virol (1987) 4.37
Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli. Nucleic Acids Res (1984) 3.94
Bacterial peptide chain release factors: conserved primary structure and possible frameshift regulation of release factor 2. Proc Natl Acad Sci U S A (1985) 3.94
Two efficient ribosomal frameshifting events are required for synthesis of mouse mammary tumor virus gag-related polyproteins. Proc Natl Acad Sci U S A (1987) 3.84
Expression of peptide chain release factor 2 requires high-efficiency frameshift. Nature (1986) 3.60
Translation framing code and frame-monitoring mechanism as suggested by the analysis of mRNA and 16 S rRNA nucleotide sequences. J Mol Biol (1987) 3.35
Specialized ribosome system: preferential translation of a single mRNA species by a subpopulation of mutated ribosomes in Escherichia coli. Proc Natl Acad Sci U S A (1987) 3.22
Feedback regulation of rRNA and tRNA synthesis and accumulation of free ribosomes after conditional expression of rRNA genes. Proc Natl Acad Sci U S A (1985) 3.16
Mutations of bacteriophage T7 that affect initiation of synthesis of the gene 0.3 protein. Proc Natl Acad Sci U S A (1978) 3.11
Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors. EMBO J (1985) 2.91
A single base change in the Shine-Dalgarno region of 16S rRNA of Escherichia coli affects translation of many proteins. Proc Natl Acad Sci U S A (1987) 2.62
Processing of adenovirus 2-induced proteins. J Virol (1973) 12.52
Isolation and characterization of ribonuclease I mutants of Escherichia coli. J Mol Biol (1966) 8.60
Primary structure of the Saccharomyces cerevisiae GAL4 gene. Mol Cell Biol (1984) 5.49
Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast. Proc Natl Acad Sci U S A (1982) 4.93
In vitro synthesis of bacteriophage lysozyme. Nature (1967) 4.71
Electrophoretic characterization of bacterial polyribosomes in agarose-acrylamide composite gels. J Mol Biol (1969) 4.69
Direct repeats flank three small nuclear RNA pseudogenes in the human genome. Cell (1981) 4.53
Mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments. Proc Natl Acad Sci U S A (1975) 4.35
Electrophoretic transfer of DNA, RNA and protein onto diazobenzyloxymethyl (DBM) - paper. Nucleic Acids Res (1980) 4.30
Recoding: dynamic reprogramming of translation. Annu Rev Biochem (1996) 4.28
Synthesis of polyoma proteins in vitro. J Mol Biol (1973) 4.16
Ribosome gymnastics--degree of difficulty 9.5, style 10.0. Cell (1990) 4.01
A dual-luciferase reporter system for studying recoding signals. RNA (1998) 3.92
Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting. Cold Spring Harb Symp Quant Biol (1987) 3.72
An overlapping protein-coding region in influenza A virus segment 3 modulates the host response. Science (2012) 3.70
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. Cell (1995) 3.64
Location and identification of the genes for adenovirus type 2 early polypeptides. Cell (1976) 3.58
Cell-free synthesis of adenovirus 2 proteins programmed by fractionated messenger RNA: a comparison of polypeptide products and messenger RNA lengths. Proc Natl Acad Sci U S A (1974) 3.52
The genes sup-7 X and sup-5 III of C. elegans suppress amber nonsense mutations via altered transfer RNA. Cell (1983) 3.26
Recoding: reprogrammed genetic decoding. Science (1992) 2.92
Further mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments. Cell (1977) 2.78
E. coli ribosomes re-phase on retroviral frameshift signals at rates ranging from 2 to 50 percent. New Biol (1989) 2.71
Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Methods Enzymol (2001) 2.67
A single base change in the Shine-Dalgarno region of 16S rRNA of Escherichia coli affects translation of many proteins. Proc Natl Acad Sci U S A (1987) 2.62
Mutations in 16S ribosomal RNA disrupt antibiotic--RNA interactions. EMBO J (1989) 2.54
Human U1 loci: genes for human U1 RNA have dramatically similar genomic environments. Cell (1982) 2.51
A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA. Science (1997) 2.43
Normal tRNAs promote ribosomal frameshifting. Cell (1979) 2.41
Evidence that a downstream pseudoknot is required for translational read-through of the Moloney murine leukemia virus gag stop codon. Proc Natl Acad Sci U S A (1991) 2.39
Transcription initiation in the histidine operon of Salmonella typhimurium. Proc Natl Acad Sci U S A (1970) 2.38
Pattern of protein synthesis in monkey cells infected by simian virus 40. J Virol (1972) 2.35
Unfolding of Escherichia coli ribosomes by removal of magnesium. J Mol Biol (1966) 2.34
Characterization of polypeptides made in vitro from bacteriophage lambda DNA. J Mol Biol (1973) 2.29
The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons. J Mol Biol (1991) 2.29
Mutant 16S ribosomal RNA: a codon-specific translational suppressor. Proc Natl Acad Sci U S A (1988) 2.26
Identification and mapping of the transcriptional and translational products of the yeast plasmid, 2mu circle. Cell (1979) 2.17
Binding of ribosomal protein S1 of Escherichia coli to the 3' end of 16S rRNA. Proc Natl Acad Sci U S A (1975) 2.16
Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA. Cell (1976) 2.16
Probing the structure of the Escherichia coli 10Sa RNA (tmRNA). RNA (1997) 2.15
Analysis of leaky viral translation termination codons in vivo by transient expression of improved beta-glucuronidase vectors. Plant Mol Biol (1990) 2.15
Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA. J Mol Biol (1999) 2.09
Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit. Proc Natl Acad Sci U S A (2001) 2.06
The control of ribonucleic acid synthesis during amino acid deprivation in Escherichia coli. J Biol Chem (1971) 2.02
Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy. Ann Neurol (2000) 2.01
Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences. Genetics (1999) 1.94
The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Mol Cell (2001) 1.94
Low activity of -galactosidase in frameshift mutants of Escherichia coli. Proc Natl Acad Sci U S A (1972) 1.94
Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines. J Biol Chem (1975) 1.93
In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus. Proc Natl Acad Sci U S A (1979) 1.88
rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift. J Bacteriol (1994) 1.88
Ribosomal frameshifting from -2 to +50 nucleotides. Prog Nucleic Acid Res Mol Biol (1990) 1.88
A nascent peptide is required for ribosomal bypass of the coding gap in bacteriophage T4 gene 60. Cell (1990) 1.87
Transcriptional slippage occurs during elongation at runs of adenine or thymine in Escherichia coli. Nucleic Acids Res (1990) 1.87
External suppression of a frameshift mutant in salmonella. J Mol Biol (1968) 1.86
Mutation at position 791 in Escherichia coli 16S ribosomal RNA affects processes involved in the initiation of protein synthesis. Proc Natl Acad Sci U S A (1989) 1.84
A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA. Nucleic Acids Res (1992) 1.76
Ribosomal RNA and protein mutants resistant to spectinomycin. EMBO J (1990) 1.75
The involvement of two distinct regions of 23 S ribosomal RNA in tRNA selection. J Mol Biol (1995) 1.74
Decoding fidelity at the ribosomal A and P sites: influence of mutations in three different regions of the decoding domain in 16S rRNA. Nucleic Acids Res (1997) 1.73
Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16 S ribosomal RNA. J Mol Biol (1990) 1.72
A map of the restriction targets in yeast 2 micron plasmid DNA cloned on bacteriophage lambda. Mol Gen Genet (1976) 1.65
Regions of DNA involved in the stringent control of plasmid-encoded rRNA in vivo. Cell (1983) 1.65
Towards a genetic dissection of the basis of triplet decoding, and its natural subversion: programmed reading frame shifts and hops. Annu Rev Genet (1991) 1.62
Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50%. J Mol Biol (1997) 1.61
Studies of 16 and 23 S ribosomal RNA of Escherichia coli using composite gel electrophoresis. J Mol Biol (1971) 1.60
Characterization of a 40S ribosomal subunit complex in polyribosomes of Saccharomyces cerevisiae treated with cycloheximide. Mol Cell Biol (1981) 1.60
Site-directed mutagenesis of ribosomal RNA. Construction and characterization of deletion mutants. J Mol Biol (1982) 1.60
Processing of the 5' end of Escherichia coli 16S ribosomal RNA. Proc Natl Acad Sci U S A (1978) 1.59
Deficiency of 1-methylguanosine in tRNA from Salmonella typhimurium induces frameshifting by quadruplet translocation. J Mol Biol (1993) 1.58
A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition. Proc Natl Acad Sci U S A (2001) 1.57
Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants. Biochimie (1987) 1.57
Binding of mammalian ribosomes to MS2 phage RNA reveals an overlapping gene encoding a lysis function. Cell (1979) 1.56
Presence and location of modified nucleotides in Escherichia coli tmRNA: structural mimicry with tRNA acceptor branches. EMBO J (1998) 1.56
Improved molecular diagnosis of dystrophinopathies in an unselected clinical cohort. Am J Med Genet A (2005) 1.54
The twenty-first amino acid. Nature (2000) 1.54
Nonlinearity in genetic decoding: homologous DNA replicase genes use alternatives of transcriptional slippage or translational frameshifting. Proc Natl Acad Sci U S A (2000) 1.53
Thermodynamic criteria for high hit rate antisense oligonucleotide design. Nucleic Acids Res (2003) 1.52