DNA linking number change induced by sequence-specific DNA-binding proteins.

Dividing a supercoiled DNA molecule into two independent topological domains. Proc Natl Acad Sci U S A (2011) 0.97

Single-molecule studies on the mechanical interplay between DNA supercoiling and H-NS DNA architectural properties. Nucleic Acids Res (2014) 0.83

DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli. Sci Rep (2016) 0.81

Stable DNA Nanomachine Based on Duplex-Triplex Transition for Ratiometric Imaging Instantaneous pH Changes in Living Cells. Anal Chem (2015) 0.76

Direct observation of a 91 bp LacI-mediated, negatively supercoiled DNA loop by atomic force microscope. FEBS Lett (2016) 0.76

Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects. Biophys Rev (2016) 0.75

Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects. Biophys Rev (2016) 0.75

The locus of sequence-directed and protein-induced DNA bending. Nature (1984) 15.05

Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees. Science (1991) 11.45

Crystal structure of a yeast TBP/TATA-box complex. Nature (1993) 7.95

Empirical estimation of protein-induced DNA bending angles: applications to lambda site-specific recombination complexes. Nucleic Acids Res (1988) 7.05

Transcriptional regulation by cAMP and its receptor protein. Annu Rev Biochem (1993) 6.49

The three operators of the lac operon cooperate in repression. EMBO J (1990) 5.45

DNA looping. Annu Rev Biochem (1992) 5.26

Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector. Gene (1989) 4.41

Chromatin reconstituted from tandemly repeated cloned DNA fragments and core histones: a model system for study of higher order structure. Cell (1985) 4.27

lac repressor forms loops with linear DNA carrying two suitably spaced lac operators. EMBO J (1987) 4.02

DNA looping and unlooping by AraC protein. Science (1990) 3.85

Plasmids containing many tandem copies of a synthetic lactose operator. Gene (1980) 3.03

DNA replication initiation: mechanisms and regulation in bacteria. Nat Rev Microbiol (2007) 2.96

Variation of half-site organization and DNA looping by AraC protein. EMBO J (1993) 2.83

Specialized nucleoprotein structures at the origin of replication of bacteriophage lambda: localized unwinding of duplex DNA by a six-protein reaction. Proc Natl Acad Sci U S A (1986) 2.79

Nucleotide sequence of the O gene and of the origin of replication in bacteriophage lambda DNA. Nucleic Acids Res (1978) 2.41

Specialized nucleoprotein structures at the origin of replication of bacteriophage lambda: complexes with lambda O protein and with lambda O, lambda P, and Escherichia coli DnaB proteins. Proc Natl Acad Sci U S A (1985) 2.19

1.9 A resolution refined structure of TBP recognizing the minor groove of TATAAAAG. Nat Struct Biol (1994) 2.17

DnaA: controlling the initiation of bacterial DNA replication and more. Annu Rev Microbiol (2006) 2.07

Regulation of the L-arabinose operon of Escherichia coli. Trends Genet (2000) 1.98

DNA supercoiling changes the spacing requirement of two lac operators for DNA loop formation with lac repressor. EMBO J (1988) 1.70

Is DNA unwound by the cyclic AMP receptor protein? Nucleic Acids Res (1982) 1.69

Ordered assembly of nucleoprotein structures at the bacteriophage lambda replication origin during the initiation of DNA replication. J Biol Chem (1989) 1.68

Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation. J Biol Chem (1992) 1.65

Determination of binding constants for cooperative site-specific protein-DNA interactions using the gel mobility-shift assay. J Biol Chem (1991) 1.57

Binding and bending of the lambda replication origin by the phage O protein. EMBO J (1985) 1.56

Promoters in the environment: transcriptional regulation in its natural context. Nat Rev Microbiol (2005) 1.52

Closed circular DNA as a probe for protein-induced structural changes. Trends Biochem Sci (1992) 1.50

Gal repressosome contains an antiparallel DNA loop. Nat Struct Biol (2001) 1.48

Bending of DNA by transcription factors. Bioessays (1993) 1.38

Interaction of the Escherichia coli Gal repressor protein with its DNA operators in vitro. Biochemistry (1990) 1.32

Building a bacterial orisome: emergence of new regulatory features for replication origin unwinding. Mol Microbiol (2005) 1.27

Lactose repressor protein: functional properties and structure. Prog Nucleic Acid Res Mol Biol (1998) 1.26

In vitro repression of the gal promoters by GalR and HU depends on the proper helical phasing of the two operators. J Biol Chem (2001) 1.22

Mechanisms of DNA bending. Curr Opin Chem Biol (1998) 1.10

Helical repeat and linking number of surface-wrapped DNA. Science (1988) 1.07

Lac repressor-operator complex. Curr Opin Struct Biol (1997) 1.01

Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins. Proc Natl Acad Sci U S A (2002) 1.01

Direct measurement of DNA unwinding angle in specific interaction between lac operator and repressor. Cold Spring Harb Symp Quant Biol (1983) 1.01

Transcription regulation by repressosome and by RNA polymerase contact. Cold Spring Harb Symp Quant Biol (1998) 1.01

Protein-induced unwinding of DNA: measurement by gel electrophoresis of complexes with DNA minicircles. Application to restriction endonuclease EcoRI, catabolite gene activator protein and lac repressor. Nucleic Acids Res (1989) 0.98

DNA bending by AraC: a negative mutant. J Bacteriol (1998) 0.95

Complete genome sequence of the apicomplexan, Cryptosporidium parvum. Science (2004) 5.64

Validation of the ITS2 region as a novel DNA barcode for identifying medicinal plant species. PLoS One (2010) 5.39

MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol (2009) 3.48

Use of ITS2 region as the universal DNA barcode for plants and animals. PLoS One (2010) 2.92

A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol (2007) 2.80

DNA methylation mediated by a microRNA pathway. Mol Cell (2010) 2.74

Celastrol attenuates hypertension-induced inflammation and oxidative stress in vascular smooth muscle cells via induction of heme oxygenase-1. Am J Hypertens (2010) 2.31

A repressor complex governs the integration of flowering signals in Arabidopsis. Dev Cell (2008) 2.24

Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1. Nat Immunol (2007) 2.15

Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice. Shock (2015) 2.00

Cytoplasmic assembly and selective nuclear import of Arabidopsis Argonaute4/siRNA complexes. Mol Cell (2012) 1.97

Genetic complementation in apicomplexan parasites. Proc Natl Acad Sci U S A (2002) 1.84

Identification of medicinal plants in the family Fabaceae using a potential DNA barcode ITS2. J Ethnopharmacol (2010) 1.71

Conventional US, US elasticity imaging, and acoustic radiation force impulse imaging for prediction of malignancy in thyroid nodules. Radiology (2014) 1.67

Complete genome sequence of Lactobacillus plantarum JDM1. J Bacteriol (2009) 1.67

Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab (2008) 1.65

Authentication of the family Polygonaceae in Chinese pharmacopoeia by DNA barcoding technique. J Ethnopharmacol (2009) 1.62

FTIP1 is an essential regulator required for florigen transport. PLoS Biol (2012) 1.61

Quantum teleportation and entanglement distribution over 100-kilometre free-space channels. Nature (2012) 1.56

Transparent nanotubular capacitors based on transplanted anodic aluminum oxide templates. ACS Appl Mater Interfaces (2015) 1.54

MOTHER OF FT AND TFL1 regulates seed germination through a negative feedback loop modulating ABA signaling in Arabidopsis. Plant Cell (2010) 1.54

Controlling the morphology of Ag nanoclusters by ion implantation to different doses and subsequent annealing. Phys Rev Lett (2006) 1.52

A modular microfluidic architecture for integrated biochemical analysis. Proc Natl Acad Sci U S A (2005) 1.52

Synthesizing a novel genetic sequential logic circuit: a push-on push-off switch. Mol Syst Biol (2010) 1.52

Virtual touch tissue quantification of acoustic radiation force impulse: a new ultrasound elastic imaging in the diagnosis of thyroid nodules. PLoS One (2012) 1.45

The Png1-Rad23 complex regulates glycoprotein turnover. J Cell Biol (2006) 1.43

Thrombocytopenia as an inexpensive, valuable predictor for survival in patients with hepatocellular carcinoma. Scand J Gastroenterol (2014) 1.43

Identification of Dendrobium species by a candidate DNA barcode sequence: the chloroplast psbA-trnH intergenic region. Planta Med (2009) 1.42

Three-dimensional reconstruction of the uterine vascular supply through vascular casting and thin slice computed tomography scanning. Minim Invasive Ther Allied Technol (2009) 1.42

Significant left atrial appendage activation delay complicating aggressive septal ablation during catheter ablation of persistent atrial fibrillation. Pacing Clin Electrophysiol (2010) 1.40

A bio-barcode assay for on-chip attomolar-sensitivity protein detection. Lab Chip (2006) 1.37

Massively parallel dip-pen nanolithography with 55 000-pen two-dimensional arrays. Angew Chem Int Ed Engl (2006) 1.34

Extensive pyrosequencing reveals frequent intra-genomic variations of internal transcribed spacer regions of nuclear ribosomal DNA. PLoS One (2012) 1.31

Genome sequence of the model medicinal mushroom Ganoderma lucidum. Nat Commun (2012) 1.30

Observation of a topological crystalline insulator phase and topological phase transition in Pb(1-x)Sn(x)Te. Nat Commun (2012) 1.30

High-resolution functional profiling of hepatitis C virus genome. PLoS Pathog (2008) 1.30

Micro magnetic stir-bar mixer integrated with parylene microfluidic channels. Lab Chip (2004) 1.29

Impact of family history of high myopia on level and onset of myopia. Invest Ophthalmol Vis Sci (2004) 1.26

Evaluating the feasibility of using candidate DNA barcodes in discriminating species of the large Asteraceae family. BMC Evol Biol (2010) 1.23

Genome-wide identification of SOC1 and SVP targets during the floral transition in Arabidopsis. Plant J (2012) 1.20

MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice. Neurobiol Aging (2010) 1.20

Integration of cytokinin and gibberellin signalling by Arabidopsis transcription factors GIS, ZFP8 and GIS2 in the regulation of epidermal cell fate. Development (2007) 1.20

China's rapidly aging population creates policy challenges in shaping a viable long-term care system. Health Aff (Millwood) (2012) 1.19

Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity. Kidney Int (2011) 1.18

Protective effects of GLP-1 on glomerular endothelium and its inhibition by PKCβ activation in diabetes. Diabetes (2012) 1.18

Collapsing SNP genotypes in case-control genome-wide association studies increases the type I error rate and power. Stat Appl Genet Mol Biol (2008) 1.17

Maximum surface charge density for triboelectric nanogenerators achieved by ionized-air injection: methodology and theoretical understanding. Adv Mater (2014) 1.17

The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms. Cardiovasc Diabetol (2014) 1.17

Topological-metal to band-insulator transition in (Bi(1-x)In(x))2Se3 thin films. Phys Rev Lett (2012) 1.16

Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus. J Virol (2013) 1.15

Cloning and characterization of a beta-glucosidase from marine microbial metagenome with excellent glucose tolerance. J Microbiol Biotechnol (2010) 1.15

Pyogenic liver abscesses associated with nonmetastatic colorectal cancers: an increasing problem in Eastern Asia. World J Gastroenterol (2012) 1.15

Intra-patient supine-prone colon registration in CT colonography using shape spectrum. Med Image Comput Comput Assist Interv (2010) 1.12

GLABROUS INFLORESCENCE STEMS modulates the regulation by gibberellins of epidermal differentiation and shoot maturation in Arabidopsis. Plant Cell (2006) 1.11

IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells. J Cancer Res Clin Oncol (2012) 1.10

Low-temperature exfoliated graphenes: vacuum-promoted exfoliation and electrochemical energy storage. ACS Nano (2009) 1.10

Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma. Clin Cancer Res (2008) 1.09

Sub-100 nm, centimeter-scale, parallel dip-pen nanolithography. Small (2005) 1.09

The Cryptosporidium oocyst wall protein is a member of a multigene family and has a homolog in Toxoplasma. Infect Immun (2004) 1.08

Detection of RASSF1A promoter hypermethylation in serum from gastric and colorectal adenocarcinoma patients. World J Gastroenterol (2008) 1.08

Subcellular curvature at the perimeter of micropatterned cells influences lamellipodial distribution and cell polarity. Cell Motil Cytoskeleton (2008) 1.08

Specific recognition of AT-rich DNA sequences by the mammalian high mobility group protein AT-hook 2: a SELEX study. Biochemistry (2007) 1.06

PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPARgamma-dependent pathway. Cell Res (2007) 1.06

Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice. EMBO J (2011) 1.05

Utility of the trnH-psbA intergenic spacer region and its combinations as plant DNA barcodes: a meta-analysis. PLoS One (2012) 1.05

The pentatricopeptide repeat (PPR) gene family, a tremendous resource for plant phylogenetic studies. New Phytol (2009) 1.03

Single cell optical imaging and spectroscopy. Chem Rev (2013) 1.03

Brown adipose tissue transplantation improves whole-body energy metabolism. Cell Res (2013) 1.03

An herbal decoction of Radix astragali and Radix angelicae sinensis promotes hematopoiesis and thrombopoiesis. J Ethnopharmacol (2009) 1.02

Transcription-coupled hypernegative supercoiling of plasmid DNA by T7 RNA polymerase in Escherichia coli topoisomerase I-deficient strains. J Mol Biol (2007) 1.02

[Research report of experimental database establishment of digitized virtual Chinese No.1 female]. Di Yi Jun Yi Da Xue Xue Bao (2003) 1.02

Giant surfactants provide a versatile platform for sub-10-nm nanostructure engineering. Proc Natl Acad Sci U S A (2013) 1.02

MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity. BMC Genomics (2014) 1.02

Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-β isoform in the endothelium. Circ Res (2013) 1.02

A review of carbon nanotube- and graphene-based flexible thin-film transistors. Small (2013) 1.01

Genome-wide biological response fingerprinting (BioReF) of the Chinese botanical formulation ISF-1 enables the selection of multiple marker genes as a potential metric for quality control. J Ethnopharmacol (2007) 1.01

An industry in the making: the emergence of institutional elder care in urban china. J Am Geriatr Soc (2011) 1.00

Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma. Cancer Lett (2012) 1.00

A rare giant gastrointestinal stromal tumor of the stomach traversing the upper abdomen: a case report and literature review. World J Surg Oncol (2012) 1.00

Multiwall boron carbonitride/carbon nanotube junction and its rectification behavior. J Am Chem Soc (2007) 1.00

Dissection of the HIV Vif interaction with human E3 ubiquitin ligase. J Virol (2010) 1.00

Momentum dependence of the superconducting gap in NdFeAsO0.9F0.1 single crystals measured by angle resolved photoemission spectroscopy. Phys Rev Lett (2008) 0.99

Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice. Inflamm Res (2010) 0.99

Genome-wide analysis of mir-548 gene family reveals evolutionary and functional implications. J Biomed Biotechnol (2012) 0.99

Predicting drug-target interactions using probabilistic matrix factorization. J Chem Inf Model (2013) 0.98

Role of CO-releasing molecules liberated CO in attenuating leukocytes sequestration and inflammatory responses in the lung of thermally injured mice. J Surg Res (2007) 0.98

Microfluidic patterning of nanodisc lipid bilayers and multiplexed analysis of protein interaction. Lab Chip (2008) 0.98

High susceptibility to liver injury in IL-27 p28 conditional knockout mice involves intrinsic interferon-γ dysregulation of CD4+ T cells. Hepatology (2013) 0.98

English sentence recognition in speech-shaped noise and multi-talker babble for English-, Chinese-, and Korean-native listeners. J Acoust Soc Am (2012) 0.98

A bacterial laccase from marine microbial metagenome exhibiting chloride tolerance and dye decolorization ability. Appl Microbiol Biotechnol (2010) 0.97

Different attitudes of Chinese patients and their families toward truth telling of different stages of cancer. Psychooncology (2007) 0.97

Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2. J Neurosci (2013) 0.97

Connexin 43 is involved in the generation of human-induced pluripotent stem cells. Hum Mol Genet (2013) 0.97

Isomerization kinetics of AT hook decapeptide solution structures. Anal Chem (2014) 0.97

Novel HBsAg markers tightly correlate with occult HBV infection and strongly affect HBsAg detection. Antiviral Res (2011) 0.97

Ligustrazine improves atherosclerosis in rat via attenuation of oxidative stress. Pharm Biol (2011) 0.96

Chinese medicine Tongxinluo modulates vascular endothelial function by inducing eNOS expression via the PI-3K/Akt/HIF-dependent signaling pathway. J Ethnopharmacol (2010) 0.96

Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury. Brain Res (2011) 0.96

A robust hybrid approach based on estimation of distribution algorithm and support vector machine for hunting candidate disease genes. ScientificWorldJournal (2013) 0.96

Attenuation of leukocytes sequestration by carbon monoxide-releasing molecules: liberated carbon monoxide in the liver of thermally injured mice. J Burn Care Res (2007) 0.96