Published in Science on October 26, 1990
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J Bacteriol (1995) 46.37
Arac/XylS family of transcriptional regulators. Microbiol Mol Biol Rev (1997) 6.56
RegulonDB (version 3.2): transcriptional regulation and operon organization in Escherichia coli K-12. Nucleic Acids Res (2001) 6.31
Cyclic AMP in prokaryotes. Microbiol Rev (1992) 5.44
The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli. Microbiol Rev (1994) 4.37
Promoters responsive to DNA bending: a common theme in prokaryotic gene expression. Microbiol Rev (1994) 3.81
Quality and position of the three lac operators of E. coli define efficiency of repression. EMBO J (1994) 2.90
Variation of half-site organization and DNA looping by AraC protein. EMBO J (1993) 2.83
DNA looping. Microbiol Rev (1992) 2.63
DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A (1991) 2.51
Use of gel retardation to analyze protein-nucleic acid interactions. Microbiol Rev (1992) 2.35
Long range repression conferring boundaries of Ultrabithorax expression in the Drosophila embryo. EMBO J (1991) 1.97
Functional domains of the AraC protein. Proc Natl Acad Sci U S A (1993) 1.78
Identification of DNA sequences recognized by VirF, the transcriptional activator of the Yersinia yop regulon. J Bacteriol (1994) 1.54
PchR, a regulator of ferripyochelin receptor gene (fptA) expression in Pseudomonas aeruginosa, functions both as an activator and as a repressor. J Bacteriol (1996) 1.46
Organization and regulation of the D-xylose operons in Escherichia coli K-12: XylR acts as a transcriptional activator. J Bacteriol (1997) 1.41
Stoichiometry of binding of CysB to the cysJIH, cysK, and cysP promoter regions of Salmonella typhimurium. J Bacteriol (1994) 1.27
Directed evolution of AraC for improved compatibility of arabinose- and lactose-inducible promoters. Appl Environ Microbiol (2007) 1.26
Cooperative binding at a distance by even-skipped protein correlates with repression and suggests a mechanism of silencing. Mol Cell Biol (1993) 1.25
Recombination by resolvase to analyse DNA communications by the SfiI restriction endonuclease. EMBO J (1996) 1.25
Identification and characterization of alcR, a gene encoding an AraC-like regulator of alcaligin siderophore biosynthesis and transport in Bordetella pertussis and Bordetella bronchiseptica. J Bacteriol (1998) 1.24
Interconvertible lac repressor-DNA loops revealed by single-molecule experiments. PLoS Biol (2008) 1.23
Determination of heat-shock transcription factor 2 stoichiometry at looped DNA complexes using scanning force microscopy. EMBO J (1995) 1.19
A domain of the even-skipped protein represses transcription by preventing TFIID binding to a promoter: repression by cooperative blocking. Mol Cell Biol (1995) 1.19
The role of rigidity in DNA looping-unlooping by AraC. Proc Natl Acad Sci U S A (2001) 1.18
Mutations in TrpI binding site II that differentially affect activation of the trpBA promoter of Pseudomonas aeruginosa. EMBO J (1991) 1.14
H-NS regulation of virulence gene expression in enteroinvasive Escherichia coli harboring the virulence plasmid integrated into the host chromosome. J Bacteriol (1995) 1.13
Mutational analysis of the regulatory region of the srfA operon in Bacillus subtilis. J Bacteriol (1993) 1.12
In vivo induction kinetics of the arabinose promoters in Escherichia coli. J Bacteriol (1995) 1.11
Enhancer-like activity of A1gR1-binding site in alginate gene activation: positional, orientational, and sequence specificity. J Bacteriol (1993) 1.11
Negative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coli. BMC Syst Biol (2011) 1.07
Studies on the binding of the Escherichia coli MelR transcription activator protein to operator sequences at the MelAB promoter. Biochem J (1992) 1.06
The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. EMBO J (1997) 1.06
Catabolite gene activator protein mutations affecting activity of the araBAD promoter. J Bacteriol (1998) 1.06
DNA binding and DNA bending by the MelR transcription activator protein from Escherichia coli. Nucleic Acids Res (1997) 1.04
Activation of the trpBA promoter of Pseudomonas aeruginosa by TrpI protein in vitro. J Bacteriol (1991) 1.03
DNA bending by the a1 and alpha 2 homeodomain proteins from yeast. Nucleic Acids Res (1995) 1.03
Twist and writhe of a DNA loop containing intrinsic bends. Proc Natl Acad Sci U S A (1993) 1.01
Understanding apparent DNA flexibility enhancement by HU and HMGB architectural proteins. J Mol Biol (2011) 1.00
DNA bending and expression of the divergent nagE-B operons. Nucleic Acids Res (1998) 0.99
Relaxation of replication control in chaperone-independent initiator mutants of plasmid P1. EMBO J (1994) 0.94
Solution structure of the DNA binding domain of AraC protein. Proteins (2009) 0.93
The linker region of AraC protein. J Bacteriol (1996) 0.92
An operator associated with autoregulation of the repressor gene in actinophage phiC31 is found in highly conserved copies in intergenic regions in the phage genome. Nucleic Acids Res (1994) 0.91
Roles of effectors in XylS-dependent transcription activation: intramolecular domain derepression and DNA binding. J Bacteriol (2008) 0.91
Sequence elements in the Escherichia coli araFGH promoter. J Bacteriol (1992) 0.91
Pheromone-inducible conjugation in Enterococcus faecalis: a model for the evolution of biological complexity? Int J Med Microbiol (2006) 0.91
Eukaryotic HMGB proteins as replacements for HU in E. coli repression loop formation. Nucleic Acids Res (2008) 0.90
Identification of mutations in three genes that interact with zeste in the control of white gene expression in Drosophila melanogaster. Genetics (1994) 0.89
Differences in the mechanism of the allosteric l-rhamnose responses of the AraC/XylS family transcription activators RhaS and RhaR. Mol Microbiol (2008) 0.89
Constitutive mutations in the Escherichia coli AraC protein. J Bacteriol (2009) 0.88
Development and application of an arabinose-inducible expression system by facilitating inducer uptake in Corynebacterium glutamicum. Appl Environ Microbiol (2012) 0.87
Sequential XylS-CTD binding to the Pm promoter induces DNA bending prior to activation. J Bacteriol (2010) 0.85
DNA linking number change induced by sequence-specific DNA-binding proteins. Nucleic Acids Res (2010) 0.85
Structural evidence suggests that antiactivator ExsD from Pseudomonas aeruginosa is a DNA binding protein. Protein Sci (2009) 0.84
Interaction of the Neisseria gonorrhoeae PilA protein with the pilE promoter involves multiple sites on the DNA. J Bacteriol (1995) 0.84
Multiscale modeling of double-helical DNA and RNA: a unification through Lie groups. J Phys Chem B (2012) 0.83
Cooperative binding of initiator protein to replication origin conferred by single amino acid substitution. Nucleic Acids Res (1994) 0.83
Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain. Nucleic Acids Res (2012) 0.83
Computational predictions of the mutant behavior of AraC. J Mol Biol (2010) 0.82
Active role of the interdomain linker of AraC. J Bacteriol (2011) 0.81
Opine-based Agrobacterium competitiveness: dual expression control of the agrocinopine catabolism (acc) operon by agrocinopines and phosphate levels. J Bacteriol (2008) 0.81
A serine protease-encoding gene (aprII) of Alteromonas sp. Strain O-7 is regulated by the iron uptake regulator (Fur) protein. Appl Environ Microbiol (2000) 0.81
Mechanism of regulation of 'chromosome kissing' induced by Fob1 and its physiological significance. Genes Dev (2015) 0.80
DNA tape measurements of AraC. Nucleic Acids Res (2007) 0.79
Formation of AraC-DNA sandwiches. Nucleic Acids Res (1993) 0.78
A functional assay in Escherichia coli to detect non-assisted interaction between galactose repressor dimers. Nucleic Acids Res (2000) 0.78
Understanding the basis of a class of paradoxical mutations in AraC through simulations. Proteins (2012) 0.77
Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR. BMC Microbiol (2011) 0.76
Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects. Biophys Rev (2016) 0.75
Ellis Englesberg and the discovery of positive control in gene regulation. Genetics (2014) 0.75
A large family of anti-activators accompanying XylS/AraC family regulatory proteins. Mol Microbiol (2016) 0.75
Epistatic Interactions in the Arabinose Cis-Regulatory Element. Mol Biol Evol (2015) 0.75
High-level expression of functionally active dengue-2 non-structural antigen 1 production in Escherichia coli. Biomed Res Int (2013) 0.75
Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects. Biophys Rev (2016) 0.75
Impact of Residual Inducer on Titratable Expression Systems. PLoS One (2015) 0.75
Pseudomonas aeruginosa AmrZ Binds to Four Sites in the algD Promoter, Inducing DNA-AmrZ Complex Formation and Transcriptional Activation. J Bacteriol (2016) 0.75
An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression. Proc Natl Acad Sci U S A (1984) 5.42
The DNA loop model for ara repression: AraC protein occupies the proposed loop sites in vivo and repression-negative mutations lie in these same sites. Proc Natl Acad Sci U S A (1986) 3.18
Variation of half-site organization and DNA looping by AraC protein. EMBO J (1993) 2.83
Missing contact probing of DNA-protein interactions. Proc Natl Acad Sci U S A (1987) 2.68
Regulation of the Escherichia coli L-arabinose operon studied by gel electrophoresis DNA binding assay. J Mol Biol (1984) 2.63
Factor necessary for ribosomal RNA synthesis. Nature (1970) 2.25
In vivo DNA loops in araCBAD: size limits and helical repeat. Proc Natl Acad Sci U S A (1989) 2.18
Positive regulation of the Escherichia coli L-rhamnose operon is mediated by the products of tandemly repeated regulatory genes. J Mol Biol (1987) 1.80
Functional domains of the AraC protein. Proc Natl Acad Sci U S A (1993) 1.78
A regulatory cascade in the induction of rhaBAD. J Mol Biol (1993) 1.54
AraC-DNA looping: orientation and distance-dependent loop breaking by the cyclic AMP receptor protein. J Mol Biol (1991) 1.52
Arm-domain interactions in AraC. J Mol Biol (1998) 1.46
Purification and properties of RhaR, the positive regulator of the L-rhamnose operons of Escherichia coli. J Mol Biol (1990) 1.45
Apo-AraC actively seeks to loop. J Mol Biol (1998) 1.29
DNA-dependent renaturation of an insoluble DNA binding protein. Identification of the RhaS binding site at rhaBAD. J Mol Biol (1994) 1.21
Reaching out. Locating and lengthening the interdomain linker in AraC protein. J Mol Biol (1994) 1.12
In vivo induction kinetics of the arabinose promoters in Escherichia coli. J Bacteriol (1995) 1.11
Transcription from the rha operon psr promoter. J Mol Biol (1990) 1.04
Hemiplegic mutations in AraC protein. J Mol Biol (1999) 1.04
Kinetics of the onset of catabolite repression in Escherichia coli as determined by lac messenger ribonucleic acid initiations and intracellular cyclic adenosine 3',5'-monophosphate levels. J Bacteriol (1975) 1.03
Cross-induction of the L-fucose system by L-rhamnose in Escherichia coli. J Bacteriol (1987) 0.99
Biophysical evidence of arm-domain interactions in AraC. Anal Biochem (2001) 0.98
Origin of chloramphenicol particle protein. J Mol Biol (1968) 0.98
Hyperproduction of araC protein from Escherichia coli. Biochemistry (1982) 0.96
DNA bending by AraC: a negative mutant. J Bacteriol (1998) 0.95
Cooperative action of the catabolite activator protein and AraC in vitro at the araFGH promoter. J Bacteriol (2000) 0.93
Equilibrium DNA-binding of AraC protein. Compensation for displaced ions. J Mol Biol (1987) 0.92
In vivo titration of araC protein. J Bacteriol (1978) 0.92
The linker region of AraC protein. J Bacteriol (1996) 0.92
In vivo association of protein fragments giving active AraC. Proteins (1996) 0.84
Transcription start site and induction kinetics of the araC regulatory gene in Escherichia coli K-12. J Mol Biol (1983) 0.83
L-arabinose operon messenger of Escherichia coli. Its inducibility and translation efficiency relative to lactose operon messenger. J Mol Biol (1971) 0.79
Formation of AraC-DNA sandwiches. Nucleic Acids Res (1993) 0.78
Stabilizing C-terminal tails on AraC. Proteins (2001) 0.78
Isolation and physical characterization of random insertions in Staphylococcal nuclease. J Mol Biol (1998) 0.76
The arabinose C gene product of Escherichia coli B-r is hyperlabile in a cell free protein synthesis system. Mol Gen Genet (1974) 0.75