PubRank

Richard N Bergman

Author PubWeight™ 464.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007 43.16
2 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
3 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
4 Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008 25.83
5 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
6 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
7 Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2008 20.66
8 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
9 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
10 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
11 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
12 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
13 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
14 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
15 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
16 Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet 2008 7.31
17 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
18 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
19 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
20 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
21 MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther 2003 4.34
22 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
23 Insulin resistance and associated compensatory responses in african-american and Hispanic children. Diabetes Care 2002 3.73
24 Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest 2008 3.51
25 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
26 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
27 Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes 2006 2.58
28 Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Ann Epidemiol 2003 2.51
29 A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes 2004 2.46
30 Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes 2010 2.44
31 Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes. J Clin Endocrinol Metab 2004 2.44
32 Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes 2004 2.43
33 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet 2012 2.34
34 Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes 2003 2.22
35 Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. Am J Physiol Endocrinol Metab 2004 2.15
36 Metabolic syndrome, hyperinsulinemia, and cancer. Am J Clin Nutr 2007 2.05
37 Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes 2006 2.03
38 Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes 2008 2.01
39 Effects of exercise training on glucose homeostasis: the HERITAGE Family Study. Diabetes Care 2005 1.96
40 Greater omentectomy improves insulin sensitivity in nonobese dogs. Obesity (Silver Spring) 2009 1.82
41 Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes 2008 1.78
42 Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes 2007 1.74
43 Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genet Epidemiol 2006 1.74
44 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
45 Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am J Physiol Endocrinol Metab 2007 1.61
46 Normal triglyceride levels despite insulin resistance in African Americans: role of lipoprotein lipase. Metabolism 2005 1.43
47 Unique effect of visceral fat on insulin sensitivity in obese Hispanic children with a family history of type 2 diabetes. Diabetes Care 2002 1.42
48 Increase in visceral fat per se does not induce insulin resistance in the canine model. Obesity (Silver Spring) 2014 1.40
49 Primacy of hepatic insulin resistance in the development of the metabolic syndrome induced by an isocaloric moderate-fat diet in the dog. Diabetes 2003 1.36
50 Direct administration of insulin into skeletal muscle reveals that the transport of insulin across the capillary endothelium limits the time course of insulin to activate glucose disposal. Diabetes 2008 1.26
51 Insulin enhances glucose-stimulated insulin secretion in healthy humans. Proc Natl Acad Sci U S A 2010 1.25
52 Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care 2010 1.25
53 Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes 2013 1.25
54 Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes 2004 1.25
55 OGTT-derived measures of insulin sensitivity are confounded by factors other than insulin sensitivity itself. Obesity (Silver Spring) 2008 1.19
56 Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes 2006 1.19
57 Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet 2005 1.18
58 FGF19 action in the brain induces insulin-independent glucose lowering. J Clin Invest 2013 1.18
59 Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice. Obesity (Silver Spring) 2012 1.17
60 Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care 2012 1.15
61 Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis study. Hypertension 2004 1.15
62 Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes 2007 1.14
63 Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study. Diabetes 2006 1.14
64 Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model. Am J Physiol Endocrinol Metab 2007 1.12
65 Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. J Clin Endocrinol Metab 2007 1.12
66 Critical role of the mesenteric depot versus other intra-abdominal adipose depots in the development of insulin resistance in young rats. Diabetes 2010 1.08
67 Burst-like control of lipolysis by the sympathetic nervous system in vivo. J Clin Invest 2003 1.08
68 Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes 2005 1.08
69 Novel canine models of obese prediabetes and mild type 2 diabetes. Am J Physiol Endocrinol Metab 2009 1.07
70 Estimating hepatic glucokinase activity using a simple model of lactate kinetics. Diabetes Care 2012 1.07
71 Exenatide sensitizes insulin-mediated whole-body glucose disposal and promotes uptake of exogenous glucose by the liver. Diabetes 2008 1.03
72 Influence of family history of type 2 diabetes on insulin sensitivity in prepubertal children. J Clin Endocrinol Metab 2003 1.03
73 Extreme insulin resistance of the central adipose depot in vivo. Diabetes 2002 1.02
74 Exogenously imposed postprandial-like rises in systemic glucose and GLP-1 do not produce an incretin effect, suggesting an indirect mechanism of GLP-1 action. Am J Physiol Endocrinol Metab 2006 1.02
75 Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog. Obesity (Silver Spring) 2013 1.02
76 Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs. Am J Physiol Endocrinol Metab 2009 1.01
77 Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study. J Clin Endocrinol Metab 2014 1.00
78 Evaluation of quantitative models of the effect of insulin on lipolysis and glucose disposal. Am J Physiol Regul Integr Comp Physiol 2008 0.98
79 Pancreatic steatosis and its relationship to β-cell dysfunction in humans: racial and ethnic variations. Diabetes Care 2012 0.97
80 Low insulin sensitivity (S(i) = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: is it associated with components of the metabolic syndrome and nontraditional risk factors? Diabetes Care 2003 0.96
81 Diet-induced obesity prevents interstitial dispersion of insulin in skeletal muscle. Diabetes 2009 0.96
82 Large size cells in the visceral adipose depot predict insulin resistance in the canine model. Obesity (Silver Spring) 2011 0.96
83 Inverse association between diabetes and altitude: a cross-sectional study in the adult population of the United States. Obesity (Silver Spring) 2014 0.95
84 CB(1) antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs. Am J Physiol Endocrinol Metab 2012 0.93
85 Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort. Diabetes 2002 0.92
86 A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes 2005 0.92
87 Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake. Diabetes 2006 0.92
88 Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity (Silver Spring) 2013 0.91
89 Experimental hyperlipidemia dramatically reduces access of insulin to canine skeletal muscle. Obesity (Silver Spring) 2009 0.91
90 Utility of a surrogate measure of insulin resistance in American Indians: the Strong Heart Study. Ethn Dis 2002 0.91
91 Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes 2004 0.90
92 Increased susceptibility to insulin resistance associated with abdominal obesity in aging rats. Obes Res 2005 0.90
93 Hepatic lipase gene variant -514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study. Diabetes 2005 0.90
94 Glucose homeostasis during short-term and prolonged exposure to high altitudes. Endocr Rev 2015 0.90
95 Exenatide can reduce glucose independent of islet hormones or gastric emptying. Am J Physiol Endocrinol Metab 2008 0.89
96 Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose uptake. Diabetes 2002 0.89
97 Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring) 2014 0.89
98 Ethnic heterogeneity in glucoregulatory function during treatment with atypical antipsychotics in patients with schizophrenia. J Psychiatr Res 2008 0.88
99 Levels of free fatty acids (FFA) are associated with insulin resistance but do not explain the relationship between adiposity and insulin resistance in Hispanic Americans: the IRAS Family Study. J Clin Endocrinol Metab 2012 0.87
100 A better index of body adiposity. Obesity (Silver Spring) 2012 0.87
101 Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study. Obesity (Silver Spring) 2009 0.86
102 Insulin sensitivity, body fat distribution, and family diabetes history: the IRAS Family Study. Obes Res 2004 0.85
103 Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns. Mol Genet Metab 2005 0.85
104 The endothelium in diabetes: its role in insulin access and diabetic complications. Rev Endocr Metab Disord 2013 0.85
105 The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study. BMC Endocr Disord 2007 0.84
106 Mechanisms responsible for excess weight loss after bariatric surgery. J Diabetes Sci Technol 2011 0.84
107 Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding. J Clin Endocrinol Metab 2002 0.83
108 The barrier within: endothelial transport of hormones. Physiology (Bethesda) 2012 0.83
109 Insulin action and distribution of tissue blood flow. J Clin Endocrinol Metab 2003 0.83
110 Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion. Diabetes 2002 0.82
111 AKA-Glucose: a program for kinetic and epidemiological analysis of frequently sampled intravenous glucose tolerance test data using database technology. Diabetes Technol Ther 2005 0.82
112 Pulsatile changes in free fatty acids augment hepatic glucose production and preserves peripheral glucose homeostasis. Am J Physiol Endocrinol Metab 2010 0.82
113 Genomic scan of glucose and insulin metabolism phenotypes: the HERITAGE Family Study. Metabolism 2003 0.82
114 Frequency of hypoglycaemia during the intravenous glucose tolerance test in overweight children. Int J Pediatr Obes 2007 0.82
115 Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype. J Clin Endocrinol Metab 2006 0.82
116 Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin-sensitive tissues. Diabetes 2004 0.81
117 Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA. PLoS One 2011 0.80
118 Performance of a multi-marker diabetes risk score in the Insulin Resistance Atherosclerosis Study (IRAS), a multi-ethnic US cohort. Diabetes Metab Res Rev 2012 0.80
119 Simplified method to isolate highly pure canine pancreatic islets. Pancreas 2012 0.78
120 Portal glucose infusion-glucose clamp measures hepatic influence on postprandial systemic glucose appearance as well as whole body glucose disposal. Am J Physiol Endocrinol Metab 2009 0.78
121 The genetic basis of glucose homeostasis. Curr Diabetes Rev 2005 0.78
122 Deconvolution as a novel approach to analyze moment-to-moment free fatty acid release. Obesity (Silver Spring) 2007 0.77
123 Investigation of the effect of acepromazine on intravenous glucose tolerance tests in dogs. Am J Vet Res 2004 0.77
124 Essentiality of portal vein receptors in hypoglycemic counterregulation: direct proof via denervation in male canines. Endocrinology 2014 0.77
125 Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q. Hum Hered 2006 0.75
126 Corrections: High-Fat Diet-Induced Insulin Resistance does not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets. PLoS One 2015 0.75
127 Estimation of metabolic flux from dominant rate constants in vivo: application to brain and heart. Metab Eng 2004 0.75
128 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
129 Watch out for the little guy. Obesity (Silver Spring) 2008 0.75
130 Truth or consequences? Obesity (Silver Spring) 2010 0.75
131 Surrogates. Obesity (Silver Spring) 2008 0.75
132 747 flyover? Obesity (Silver Spring) 2009 0.75
133 Association of chairs of departments of physiology 2005 survey results. Physiologist 2006 0.75
134 Swan song. Obesity (Silver Spring) 2012 0.75
135 Mechanism of action in dogs of slow-acting insulin analog O346. J Clin Endocrinol Metab 2003 0.75
136 Pollyanna or Debbie Downer? Obesity (Silver Spring) 2009 0.75
137 What for genetics? Obesity (Silver Spring) 2008 0.75
138 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75