Published in J Nat Prod on April 23, 2010
A comprehensive review of glycosylated bacterial natural products. Chem Soc Rev (2015) 1.13
Mandelalides A-D, cytotoxic macrolides from a new Lissoclinum species of South African tunicate. J Org Chem (2012) 0.87
Actinomycetes from the South China Sea sponges: isolation, diversity, and potential for aromatic polyketides discovery. Front Microbiol (2015) 0.85
Phylogenetic diversity of actinobacteria associated with soft coral Alcyonium gracllimum and stony coral Tubastraea coccinea in the East China Sea. Microb Ecol (2013) 0.81
Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms. Mar Drugs (2017) 0.75
A new anthracycline-type metabolite from Streptomyces sp. NEAU-L3. J Antibiot (Tokyo) (2017) 0.75
Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. J Am Chem Soc (2002) 1.82
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells. J Biol Chem (2006) 1.74
Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. Cancer Res (2009) 1.53
Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis. J Biol Chem (2002) 1.46
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. J Am Chem Soc (2005) 1.40
Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites. ACS Synth Biol (2013) 1.40
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proc Natl Acad Sci U S A (2007) 1.29
Interaction of telomestatin with the telomeric single-strand overhang. J Biol Chem (2004) 1.27
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways. Oncogene (2003) 1.26
Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity. EMBO J (2013) 1.25
Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase. Cancer Sci (2007) 1.23
Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life. J Control Release (2007) 1.11
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. J Am Chem Soc (2007) 1.10
Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice. Biomaterials (2006) 1.07
Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models. Cancer Sci (2008) 1.06
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. Blood (2010) 1.02
A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis. Nat Chem Biol (2012) 0.97
Streptomyces associated with a marine sponge Haliclona sp.; biosynthetic genes for secondary metabolites and products. Environ Microbiol (2010) 0.95
Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes. ChemMedChem (2007) 0.94
Sponge-derived Streptomyces producing isoprenoids via the mevalonate pathway. J Nat Prod (2010) 0.94
Novel in vitro protein fragment complementation assay applicable to high-throughput screening in a 1536-well format. J Biomol Screen (2009) 0.94
Total synthesis of spiruchostatin B aided by an automated synthesizer. Org Biomol Chem (2011) 0.93
Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines. J Antibiot (Tokyo) (2012) 0.93
Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78. Neurosci Res (2009) 0.92
Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis. Acta Crystallogr D Biol Crystallogr (2002) 0.92
Molecular determinants of microbial resistance to thiopeptide antibiotics. J Am Chem Soc (2010) 0.90
JBIR-137 and JBIR-138, new secondary metabolites from Aspergillus sp. fA75. J Antibiot (Tokyo) (2012) 0.90
Novel GRP78 molecular chaperone expression down-regulators JBIR-04 and -05 isolated from Streptomyces violaceoniger. J Antibiot (Tokyo) (2007) 0.90
Increased chemotherapeutic activity of camptothecin in cancer cells by siRNA-induced silencing of WRN helicase. Biol Pharm Bull (2007) 0.90
Streptomyces tateyamensis sp. nov., Streptomyces marinus sp. nov. and Streptomyces haliclonae sp. nov., isolated from the marine sponge Haliclona sp. Int J Syst Evol Microbiol (2010) 0.90
Distribution of the 3-hydroxyl-3-methylglutaryl coenzyme A reductase gene and isoprenoid production in marine-derived Actinobacteria. FEMS Microbiol Lett (2009) 0.89
Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator. Toxicology (2006) 0.89
Structure of tyroscherin, an antitumor antibiotic against IGF-1-dependent cells from Pseudallescheria sp. J Antibiot (Tokyo) (2004) 0.89
Isolation of 2 new naphthablin analogs, JBIR-79 and JBIR-80, from Streptomyces sp. RI24. J Antibiot (Tokyo) (2010) 0.89
Spectomycin B1 as a novel SUMOylation inhibitor that directly binds to SUMO E2. ACS Chem Biol (2013) 0.89
JBIR-83 and JBIR-84, new promothiocin derivatives, isolated from Streptomyces sp. RI19. J Antibiot (Tokyo) (2010) 0.88
Urukthapelstatin A, a novel cytotoxic substance from marine-derived Mechercharimyces asporophorigenens YM11-542. I. Fermentation, isolation and biological activities. J Antibiot (Tokyo) (2007) 0.88
A novel indole-diterpenoid, JBIR-03 with anti-MRSA activity from Dichotomomyces cejpii var. cejpii NBRC 103559. J Antibiot (Tokyo) (2007) 0.88
Naphthoquinone-like polyketide isolated from Streptomyces sp. RI-77 and its predicted biosynthetic pathway. J Nat Prod (2011) 0.88
Aminocaprophenone- and pyrrolidine-type alkaloids from the leaves of Ficus septica. J Nat Prod (2009) 0.87
New angucycline C-glycosides from Streptomyces sp. RI33. J Antibiot (Tokyo) (2011) 0.87
New glycosylated derivatives of versipelostatin, the GRP78/Bip molecular chaperone down-regulator, from Streptomyces versipellis 4083-SVS6. Org Biomol Chem (2009) 0.87
Relative and absolute configuration of versipelostatin, a down-regulator of molecular chaperone GRP78 expression. Org Lett (2007) 0.87
JBIR-31, a new teleocidin analog, produced by salt-requiring Streptomyces sp. NBRC 105896 isolated from a marine sponge. J Antibiot (Tokyo) (2009) 0.86
Structure of aspochalasin H, a new member of the aspochalasin family. J Antibiot (Tokyo) (2002) 0.85
Three new depsipeptides, JBIR-113, JBIR-114 and JBIR-115, isolated from a marine sponge-derived Penicillium sp. fS36. J Antibiot (Tokyo) (2011) 0.85
New sesquiterpenes, JBIR-27 and -28, isolated from a tunicate-derived fungus, Penicillium sp. SS080624SCf1. J Antibiot (Tokyo) (2009) 0.84
Selective cytotoxic activity of valinomycin against HT-29 Human colon carcinoma cells via down-regulation of GRP78. Biol Pharm Bull (2006) 0.84
Oximidines I and II: Novel Antitumor Macrolides from Pseudomonas sp. J Org Chem (1999) 0.84
Combinatorial synthesis of deoxyhexasaccharides related to the landomycin A sugar moiety, based on an orthogonal deprotection strategy. Chem Asian J (2010) 0.83
Analysis of the biological activity of a novel 24-membered macrolide JBIR-19 in Saccharomyces cerevisiae by the morphological imaging program CalMorph. FEMS Yeast Res (2012) 0.83
Ammocidins B, C and D, new cytotoxic 20-membered macrolides from Saccharothrix sp. AJ9571. J Antibiot (Tokyo) (2009) 0.83
JBIR-23 and -24, novel anticancer agents from Streptomyces sp. AK-AB27. Org Lett (2009) 0.83
JBIR-22, an inhibitor for protein-protein interaction of the homodimer of proteasome assembly factor 3. J Nat Prod (2010) 0.83
Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin. Toxicon (2009) 0.83
Identification and biosynthesis of new acyloins from the thermophilic bacterium Thermosporothrix hazakensis SK20-1(T). Chembiochem (2014) 0.83
JBIR-15, a new aspochracin derivative, isolated from a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04. Biosci Biotechnol Biochem (2009) 0.82
Absolute structure of prunustatin A, a novel GRP78 molecular chaperone down-regulator. Org Lett (2007) 0.82
JBIR-56 and JBIR-57, 2(1H)-pyrazinones from a marine sponge-derived Streptomyces sp. SpD081030SC-03. J Nat Prod (2011) 0.82
New tensidols, JBIR-86 and JBIR-87, isolated from Aspergillus sp. fJ80. J Antibiot (Tokyo) (2010) 0.82
A new cyclizidine analog-JBIR-102-from Saccharopolyspora sp. RL78 isolated from mangrove soil. J Antibiot (Tokyo) (2011) 0.82
A novel human dynactin-associated protein, dynAP, promotes activation of Akt, and ergosterol-related compounds induce dynAP-dependent apoptosis of human cancer cells. Mol Cancer Ther (2010) 0.81
Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase. Cancer Res (2003) 0.81
JBIR-52, a new antimycin-like compound, from Streptomyces sp. ML55. J Antibiot (Tokyo) (2009) 0.81
Solid-phase total synthesis of (-)-apratoxin A and its analogues and their biological evaluation. Chem Asian J (2011) 0.81
Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator. J Cell Physiol (2008) 0.81
Novel siderophore, JBIR-16, isolated from Nocardia tenerifensis NBRC 101015. J Antibiot (Tokyo) (2009) 0.80
Isolation of a novel macrocyclic dilactone-JBIR-101-from Promicromonospora sp. RL26. J Antibiot (Tokyo) (2011) 0.80
JBIR-94 and JBIR-125, antioxidative phenolic compounds from Streptomyces sp. R56-07. J Nat Prod (2012) 0.79
New aureothin derivative, alloaureothin, from Streptomyces sp. MM23. J Antibiot (Tokyo) (2007) 0.79
JBIR-59, a new sorbicillinoid, from a marine-derived fungus Penicillium citrinum SpI080624G1f01. J Antibiot (Tokyo) (2010) 0.79
JBIR-58, a new salicylamide derivative, isolated from a marine sponge-derived Streptomyces sp. SpD081030ME-02. J Antibiot (Tokyo) (2010) 0.79
A new angucycline and a new butenolide isolated from lichen-derived Streptomyces spp. J Antibiot (Tokyo) (2010) 0.79
A novel versipelostatin analogue, versipelostatin F isolated from Streptomyces versipellis 4083-SVS6. J Antibiot (Tokyo) (2008) 0.79
Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole. Org Biomol Chem (2010) 0.78
JBIR-44, a new bromotyrosine compound from a marine sponge Psammaplysilla purpurea. J Antibiot (Tokyo) (2009) 0.78
Macrocyclic hexaoxazoles as sequence- and mode-selective G-quadruplex binders. Angew Chem Int Ed Engl (2008) 0.78
Tetrapeptides possessing a unique skeleton, JBIR-34 and JBIR-35, isolated from a sponge-derived actinomycete, Streptomyces sp. Sp080513GE-23. J Nat Prod (2010) 0.78
Trichostatin analogues JBIR-109, JBIR-110, and JBIR-111 from the marine sponge-derived Streptomyces sp. RM72. J Nat Prod (2012) 0.78
New species of actinomycetes do not always produce new compounds with high frequency. J Antibiot (Tokyo) (2011) 0.78
JBIR-107, a new metabolite from the marine-sponge-derived actinomycete, Streptomyces tateyamensis NBRC 105047. Biosci Biotechnol Biochem (2013) 0.78
JBIR-25, a novel antioxidative agent from Hyphomycetes sp. CR28109. J Antibiot (Tokyo) (2009) 0.77
Novel 24-membered macrolides, JBIR-19 and -20 isolated from Metarhizium sp. fE61. J Antibiot (Tokyo) (2009) 0.77
A novel antimycin-like compound, JBIR-06, from Streptomyces sp. ML55. J Antibiot (Tokyo) (2008) 0.77
Cation involvement in telomestatin binding to g-quadruplex DNA. J Nucleic Acids (2010) 0.77
Discovery of a pimaricin analog JBIR-13, from Streptomyces bicolor NBRC 12746 as predicted by sequence analysis of type I polyketide synthase gene. Appl Microbiol Biotechnol (2009) 0.77