Published in J Biol Chem on March 01, 2010
Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling. Biochim Biophys Acta (2013) 1.37
Retroviral matrix and lipids, the intimate interaction. Retrovirology (2011) 0.96
CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses. Mol Cell Biol (2013) 0.86
Lck, Membrane Microdomains, and TCR Triggering Machinery: Defining the New Rules of Engagement. Front Immunol (2012) 0.85
How does the kinase Lck phosphorylate the T cell receptor? Spatial organization as a regulatory mechanism. Front Immunol (2012) 0.84
The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor. Sci Rep (2015) 0.83
Neutral sphingomyelinase in physiological and measles virus induced T cell suppression. PLoS Pathog (2014) 0.81
Cytoplasmic domain of P-selectin glycoprotein ligand-1 facilitates dimerization and export from the endoplasmic reticulum. J Biol Chem (2011) 0.81
Cytoskeletal modulation of lipid interactions regulates Lck kinase activity. J Biol Chem (2012) 0.80
CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts. J Immunol (2013) 0.78
n-3 polyunsaturated fatty acids suppress CD4(+) T cell proliferation by altering phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P2] organization. Biochim Biophys Acta (2015) 0.76
Triggering signaling pathways using F-actin self-organization. Sci Rep (2016) 0.76
Functional rafts in cell membranes. Nature (1997) 38.89
Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science (2002) 18.89
The immunological synapse: a molecular machine controlling T cell activation. Science (1999) 17.41
Three-dimensional segregation of supramolecular activation clusters in T cells. Nature (1998) 14.14
Lipid rafts reconstituted in model membranes. Biophys J (2001) 9.19
GPI-anchored proteins are organized in submicron domains at the cell surface. Nature (1998) 8.18
Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell (2005) 7.27
Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature (2008) 6.38
Nanoscale organization of multiple GPI-anchored proteins in living cell membranes. Cell (2004) 5.61
Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy. EMBO J (2000) 5.54
Membrane compartmentation is required for efficient T cell activation. Immunity (1998) 5.00
Lipid rafts: contentious only from simplistic standpoints. Nat Rev Mol Cell Biol (2006) 4.94
The immunological synapse balances T cell receptor signaling and degradation. Science (2003) 4.94
LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity (1998) 4.56
T cell receptor signaling precedes immunological synapse formation. Science (2002) 4.56
TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. Nat Immunol (2009) 4.22
Microdomains of GPI-anchored proteins in living cells revealed by crosslinking. Nature (1998) 4.08
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature (2000) 4.01
Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer. J Cell Biol (1998) 3.92
Continuous T cell receptor signaling required for synapse maintenance and full effector potential. Nat Immunol (2003) 3.88
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 3.78
Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophys J (1991) 3.47
Molecular dynamics and interactions for creation of stimulation-induced stabilized rafts from small unstable steady-state rafts. Traffic (2004) 3.45
T-cell-antigen recognition and the immunological synapse. Nat Rev Immunol (2003) 3.38
Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proc Natl Acad Sci U S A (1989) 2.99
Dynamic molecular confinement in the plasma membrane by microdomains and the cytoskeleton meshwork. EMBO J (2006) 2.87
Staging and resetting T cell activation in SMACs. Nat Immunol (2002) 2.85
Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse. Nat Immunol (2002) 2.79
Nanoclusters of GPI-anchored proteins are formed by cortical actin-driven activity. Cell (2008) 2.74
The kinetic-segregation model: TCR triggering and beyond. Nat Immunol (2006) 2.70
Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase. Proc Natl Acad Sci U S A (1989) 2.70
Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction. Mol Cell Biol (1994) 2.70
Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts. Proc Natl Acad Sci U S A (1988) 2.60
Lipid raft proteins have a random distribution during localized activation of the T-cell receptor. Nat Cell Biol (2004) 2.57
Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes. Mol Biol Cell (2004) 2.50
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc Natl Acad Sci U S A (1991) 2.45
T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand. Nature (2005) 2.42
Condensation of the plasma membrane at the site of T lymphocyte activation. J Cell Biol (2005) 2.33
Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains. J Cell Biol (1996) 2.19
The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality. Immunity (2008) 2.13
Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk. Nature (1993) 2.05
Actin polymerization serves as a membrane domain switch in model lipid bilayers. Biophys J (2006) 2.00
A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation. Proc Natl Acad Sci U S A (2000) 1.89
Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling. EMBO J (2009) 1.84
Visualizing membrane microdomains by Laurdan 2-photon microscopy. Mol Membr Biol (2006) 1.77
Imaging antigen-induced PI3K activation in T cells. Nat Immunol (2002) 1.76
Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells. J Cell Biol (2001) 1.70
Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin. J Cell Biol (2007) 1.61
Cytoskeleton-membrane interactions in membrane raft structure. Cell Mol Life Sci (2009) 1.59
Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation. Mol Cell Biol (1990) 1.57
CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse. Nat Cell Biol (2006) 1.56
Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling. Proc Natl Acad Sci U S A (2006) 1.45
Clustering of membrane raft proteins by the actin cytoskeleton. J Biol Chem (2007) 1.42
Homo-FRET imaging enables quantification of protein cluster sizes with subcellular resolution. Biophys J (2009) 1.38
Functional implications of plasma membrane condensation for T cell activation. PLoS One (2008) 1.37
The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling. J Cell Biol (2003) 1.25
Cutting edge: quantitative imaging of raft accumulation in the immunological synapse. J Immunol (2002) 1.18
Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation. EMBO Rep (2008) 1.18
Glycolipid-enriched membrane domains are assembled into membrane patches by associating with the actin cytoskeleton. Exp Cell Res (2001) 1.14
Fluorescence resonance energy transfer between lipid probes detects nanoscopic heterogeneity in the plasma membrane of live cells. Biophys J (2007) 1.12
Merging complexes: properties of membrane raft assembly during lymphocyte signaling. Trends Immunol (2005) 1.09
Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem (2008) 1.09
Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes. J Immunol (2002) 1.07
Palmitoylation-dependent plasma membrane transport but lipid raft-independent signaling by linker for activation of T cells. J Immunol (2009) 1.00
Visualization of antigen presentation by actin-mediated targeting of glycolipid-enriched membrane domains to the immune synapse of B cell APCs. J Immunol (2004) 0.95
TCR/CD28-stimulated actin dynamics are required for NFAT1-mediated transcription of c-rel leading to CD28 response element activation. J Immunol (2007) 0.92
Rac is involved in early TCR signaling. J Immunol (2000) 0.90
Photobleaching of YFP does not produce a CFP-like species that affects FRET measurements. Nat Methods (2006) 0.87
Cytoskeleton-membrane interactions in membrane raft structure. Cell Mol Life Sci (2009) 1.59
Clustering of membrane raft proteins by the actin cytoskeleton. J Biol Chem (2007) 1.42
Tissue factor-dependent coagulation is preferentially up-regulated within arterial branching areas in a baboon model of Escherichia coli sepsis. Am J Pathol (2005) 1.37
Compartmentalization of phosphatidylinositol 4,5-bisphosphate signaling evidenced using targeted phosphatases. J Biol Chem (2008) 1.15
Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility. J Biol Chem (2006) 1.15
Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P₂ between distinct membrane pools. J Cell Sci (2011) 1.12
Surgical staging in patients with ovarian tumors of low malignant potential. Obstet Gynecol (2002) 1.09
Prospective comparison of brush cytology, viral culture, and histology for the diagnosis of ulcerative esophagitis in AIDS. Clin Gastroenterol Hepatol (2004) 1.01
Visualization of antigen presentation by actin-mediated targeting of glycolipid-enriched membrane domains to the immune synapse of B cell APCs. J Immunol (2004) 0.95
Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility. Nucleic Acids Res (2004) 0.93
T cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses. J Immunol (2003) 0.90
Signal-dependent slow leukocyte rolling does not require cytoskeletal anchorage of P-selectin glycoprotein ligand-1 (PSGL-1) or integrin αLβ2. J Biol Chem (2012) 0.89
Very good inter-rater reliability of Engel and ILAE epilepsy surgery outcome classifications in a series of 76 patients. Seizure (2011) 0.85
Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding. BMC Biochem (2011) 0.84
Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals. J Immunol (2007) 0.82
Cytoplasmic domain of P-selectin glycoprotein ligand-1 facilitates dimerization and export from the endoplasmic reticulum. J Biol Chem (2011) 0.81
Proteomic profiling of mature CD10+ B-cell lymphomas. Am J Clin Pathol (2005) 0.81
Cytoskeletal modulation of lipid interactions regulates Lck kinase activity. J Biol Chem (2012) 0.80
CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts. J Immunol (2013) 0.78
An interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J recombinase complex. Protein Sci (2015) 0.78
Spatial Segregation of Phosphatidylinositol 4,5-Bisphosphate (PIP(2)) Signaling in Immune Cell Functions. Immunol Endocr Metab Agents Med Chem (2008) 0.78
SPACA7 is a novel male germ cell-specific protein localized to the sperm acrosome that is involved in fertilization in mice. Biol Reprod (2014) 0.76
Unusual fallopian tube neoplasm in a 10-year-old patient with Proteus syndrome: a case report and review of the literature. Pediatr Dev Pathol (2006) 0.75
Visualization of transfer of a fluorescently-labeled membrane raft protein to T cells using lentivirus. Gene Ther Mol Biol (2005) 0.75
Atypical lymphoid cells in cerebrospinal fluid in acute Epstein Barr virus infection: a case report demonstrating a pitfall in cerebrospinal fluid cytology. Acta Cytol (2008) 0.75