Published in Proc Natl Acad Sci U S A on March 01, 2010
Recombinant origin of the retrovirus XMRV. Science (2011) 3.54
The human retrovirus XMRV in prostate cancer and chronic fatigue syndrome. Nat Rev Urol (2010) 1.94
Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs. J Virol (2010) 1.85
BST-2/tetherin: a new component of the innate immune response to enveloped viruses. Trends Microbiol (2010) 1.82
Tetherin restricts productive HIV-1 cell-to-cell transmission. PLoS Pathog (2010) 1.73
Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities. PLoS Pathog (2012) 1.60
The mouse "xenotropic" gammaretroviruses and their XPR1 receptor. Retrovirology (2010) 1.35
Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations. Proc Natl Acad Sci U S A (2010) 1.29
Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV. PLoS One (2010) 1.28
Infection, viral dissemination, and antibody responses of rhesus macaques exposed to the human gammaretrovirus XMRV. J Virol (2011) 1.28
No evidence for XMRV in German CFS and MS patients with fatigue despite the ability of the virus to infect human blood cells in vitro. PLoS One (2010) 1.25
Severe restriction of xenotropic murine leukemia virus-related virus replication and spread in cultured human peripheral blood mononuclear cells. J Virol (2011) 1.18
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Early events in retrovirus XMRV infection of the wild-derived mouse Mus pahari. J Virol (2010) 1.13
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Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity. Virology (2010) 1.09
Counteraction of the multifunctional restriction factor tetherin. Front Microbiol (2014) 1.09
The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3. J Virol (2010) 1.09
Common inbred strains of the laboratory mouse that are susceptible to infection by mouse xenotropic gammaretroviruses and the human-derived retrovirus XMRV. J Virol (2010) 1.09
XMRV and prostate cancer--a 'final' perspective. Nat Rev Urol (2012) 1.08
Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors. Retrovirology (2010) 1.03
Tetherin inhibits prototypic foamy virus release. Virol J (2011) 1.02
Retroelements versus APOBEC3 family members: No great escape from the magnificent seven. Front Microbiol (2012) 0.99
The interferon-inducible host factor bone marrow stromal antigen 2/tetherin restricts virion release, but is it actually a viral restriction factor? J Interferon Cytokine Res (2010) 0.98
The xenotropic murine leukemia virus-related retrovirus debate continues at first international workshop. Retrovirology (2010) 0.98
Recombinant origin, contamination, and de-discovery of XMRV. Curr Opin Virol (2012) 0.96
Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells. J Virol (2010) 0.96
Characterization, mapping, and distribution of the two XMRV parental proviruses. J Virol (2011) 0.93
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques. J Virol (2012) 0.93
Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation. J Virol (2014) 0.90
The gammaretroviral p12 protein has multiple domains that function during the early stages of replication. Retrovirology (2012) 0.90
No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe. PLoS One (2011) 0.89
Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons. DNA Cell Biol (2011) 0.89
Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms. Retrovirology (2012) 0.88
Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo. PLoS Pathog (2014) 0.87
Murine leukemia viruses: objects and organisms. Adv Virol (2011) 0.87
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor. J Virol (2013) 0.86
APOBEC3G complexes decrease human immunodeficiency virus type 1 production. J Virol (2011) 0.84
No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses. PLoS One (2012) 0.83
Zinc-finger antiviral protein inhibits XMRV infection. PLoS One (2012) 0.83
Phylogeny-directed search for murine leukemia virus-like retroviruses in vertebrate genomes and in patients suffering from myalgic encephalomyelitis/chronic fatigue syndrome and prostate cancer. Adv Virol (2011) 0.83
NF-kappaB activation stimulates transcription and replication of retrovirus XMRV in human B-lineage and prostate carcinoma cells. J Virol (2011) 0.83
Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients. Adv Virol (2011) 0.81
In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins. Virology (2011) 0.81
Downregulation of APOBEC3G by xenotropic murine leukemia-virus related virus (XMRV) in prostate cancer cells. Virol J (2011) 0.80
Absence of XMRV in peripheral blood mononuclear cells of ARV-treatment naïve HIV-1 infected and HIV-1/HCV coinfected individuals and blood donors. PLoS One (2012) 0.80
Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model. PLoS One (2011) 0.80
Utilization of replication-competent XMRV reporter-viruses reveals severe viral restriction in primary human cells. PLoS One (2013) 0.79
Origin of XMRV and its demise as a human pathogen associated with chronic fatigue syndrome. Viruses (2011) 0.79
Restriction of porcine endogenous retrovirus by porcine APOBEC3 cytidine deaminases. J Virol (2011) 0.79
Incorporation of mouse APOBEC3 into murine leukemia virus virions decreases the activity and fidelity of reverse transcriptase. J Virol (2014) 0.78
Long-term infection and vertical transmission of a gammaretrovirus in a foreign host species. PLoS One (2012) 0.78
Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection. PLoS One (2012) 0.78
Of Mice and Men: On the Origin of XMRV. Front Microbiol (2011) 0.77
Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H. Biosci Rep (2012) 0.77
In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models. J Virol (2016) 0.76
XMRV Discovery and Prostate Cancer-Related Research. Adv Virol (2011) 0.76
Is XMRV a causal virus for prostate cancer? Asian J Androl (2011) 0.75
A new approach to establish a cell line with reduced risk of endogenous retroviruses. PLoS One (2013) 0.75
Effects of the inner nuclear membrane proteins SUN1/UNC-84A and SUN2/UNC-84B on the early steps of HIV-1 infection. J Virol (2017) 0.75
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature (2002) 21.53
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature (2004) 17.56
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature (2008) 14.99
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature (2003) 13.24
DNA deamination mediates innate immunity to retroviral infection. Cell (2003) 12.10
Host-range restrictions of murine leukemia viruses in mouse embryo cell cultures. J Virol (1970) 11.14
Retracted Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. Science (2009) 10.76
Retracted Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. PLoS Pathog (2006) 10.08
Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell (2003) 9.48
The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe (2008) 9.27
Positional cloning of the mouse retrovirus restriction gene Fv1. Nature (1996) 7.01
Retracted XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors. Proc Natl Acad Sci U S A (2009) 6.72
Cytidine deamination of retroviral DNA by diverse APOBEC proteins. Curr Biol (2004) 6.51
HIV-1 accessory proteins--ensuring viral survival in a hostile environment. Cell Host Microbe (2008) 5.90
Trim5alpha protein restricts both HIV-1 and murine leukemia virus. Proc Natl Acad Sci U S A (2004) 5.31
Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha. Proc Natl Acad Sci U S A (2004) 5.15
The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. Proc Natl Acad Sci U S A (2004) 5.08
Tetherin inhibits HIV-1 release by directly tethering virions to cells. Cell (2009) 5.06
TRIM family proteins: retroviral restriction and antiviral defence. Nat Rev Microbiol (2005) 4.89
An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors. Proc Natl Acad Sci U S A (2007) 4.77
Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin. J Virol (2008) 4.72
TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. Proc Natl Acad Sci U S A (2004) 4.60
Prevalence of human gammaretrovirus XMRV in sporadic prostate cancer. J Clin Virol (2008) 4.25
Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2. PLoS Pathog (2009) 4.24
Nef proteins from simian immunodeficiency viruses are tetherin antagonists. Cell Host Microbe (2009) 4.11
Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients. Retrovirology (2009) 4.11
Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance. Virology (1996) 3.31
Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein. J Virol (2009) 3.13
Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets. J Virol (2009) 2.95
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APOBEC proteins and intrinsic resistance to HIV-1 infection. Philos Trans R Soc Lond B Biol Sci (2009) 2.40
APOBEC3 inhibits mouse mammary tumour virus replication in vivo. Nature (2007) 2.28
All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction. J Virol (2006) 2.26
Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration. Proc Natl Acad Sci U S A (2009) 2.21
Differential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion. J Virol (2005) 2.20
APOBEC3G genetic variants and their influence on the progression to AIDS. J Virol (2004) 1.97
Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science (2008) 1.97
Interactions between host and viral genomes in mouse leukemia. Annu Rev Genet (1977) 1.93
Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression. Blood (2007) 1.93
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo. J Virol (2008) 1.74
Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. J Biol Chem (2006) 1.68
Polymorphisms of the cell surface receptor control mouse susceptibilities to xenotropic and polytropic leukemia viruses. J Virol (1999) 1.55
Six host range variants of the xenotropic/polytropic gammaretroviruses define determinants for entry in the XPR1 cell surface receptor. Retrovirology (2009) 1.55
Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms. Curr Biol (2006) 1.53
Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene. Virology (2009) 1.51
Interactions of murine APOBEC3 and human APOBEC3G with murine leukemia viruses. J Virol (2008) 1.50
Species-specific restriction of apobec3-mediated hypermutation. J Virol (2007) 1.46
Further investigation of simian immunodeficiency virus Vif function in human cells. J Virol (2004) 1.46
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A natural human retrovirus efficiently complements vectors based on murine leukemia virus. PLoS One (2008) 1.12
The incorporation of APOBEC3 proteins into murine leukemia viruses. Virology (2008) 0.90
Are viruses inhibited by APOBEC3 molecules from their host species? PLoS Pathog (2009) 0.87
DNA deamination mediates innate immunity to retroviral infection. Cell (2003) 12.10
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature (2011) 5.28
Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin. J Virol (2008) 4.72
Plasma membrane is the site of productive HIV-1 particle assembly. PLoS Biol (2006) 4.43
Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants. PLoS Pathog (2009) 4.18
Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome. Retrovirology (2010) 4.18
A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1. Proc Natl Acad Sci U S A (2004) 4.06
Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein. J Virol (2009) 3.13
APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G. J Biol Chem (2006) 3.03
APOBEC-mediated viral restriction: not simply editing? Trends Biochem Sci (2007) 2.80
All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction. J Virol (2006) 2.26
Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses. Cell Host Microbe (2012) 2.03
Host factors involved in retroviral budding and release. Nat Rev Microbiol (2011) 1.94
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin. PLoS Pathog (2010) 1.94
Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells. J Virol (2010) 1.83
Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates. Proc Natl Acad Sci U S A (2009) 1.73
Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein. J Virol (2010) 1.60
TRIM5 alpha cytoplasmic bodies are highly dynamic structures. Mol Biol Cell (2007) 1.47
Further investigation of simian immunodeficiency virus Vif function in human cells. J Virol (2004) 1.46
Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences. J Virol (2008) 1.36
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Novel escape mutants suggest an extensive TRIM5α binding site spanning the entire outer surface of the murine leukemia virus capsid protein. PLoS Pathog (2011) 1.24
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A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. PLoS Pathog (2012) 1.21
Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection. Retrovirology (2013) 1.16
Lv2, a novel postentry restriction, is mediated by both capsid and envelope. J Virol (2004) 1.16
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Structural and functional analysis of prehistoric lentiviruses uncovers an ancient molecular interface. Cell Host Microbe (2010) 1.11
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Separable determinants of subcellular localization and interaction account for the inability of group O HIV-1 Vpu to counteract tetherin. J Virol (2011) 1.05
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The gammaretroviral p12 protein has multiple domains that function during the early stages of replication. Retrovirology (2012) 0.90
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The tale of xenotropic murine leukemia virus-related virus. J Gen Virol (2012) 0.89
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No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses. PLoS One (2012) 0.83