Alexander J Whitworth

Author PubWeight™ 55.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci U S A 2003 7.57
3 The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A 2008 7.41
4 Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci U S A 2010 5.17
5 Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. Nat Neurosci 2009 2.35
6 Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr Biol 2005 2.35
7 PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet 2010 2.30
8 Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Hum Mol Genet 2005 1.61
9 Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations. Open Biol 2011 1.42
10 The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nat Neurosci 2013 1.19
11 How could Parkin-mediated ubiquitination of mitofusin promote mitophagy? Autophagy 2010 1.11
12 Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1. Exp Cell Res 2010 1.03
13 TRAP1 rescues PINK1 loss-of-function phenotypes. Hum Mol Genet 2013 0.93
14 Molecular mechanisms of PINK1-related neurodegeneration. Curr Neurol Neurosci Rep 2011 0.87
15 Modeling pathogenic mutations of human twinkle in Drosophila suggests an apoptosis role in response to mitochondrial defects. PLoS One 2012 0.86
16 The many faces of mitophagy. EMBO Rep 2014 0.79
17 Translating translation: regulated protein translation as a biomedical intervention. Fly (Austin) 2009 0.77