Published in Circulation on March 01, 2010
Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling. Antioxid Redox Signal (2013) 1.48
The emerging role of the thioredoxin system in angiogenesis. Arterioscler Thromb Vasc Biol (2010) 1.18
Gene therapy for ischemic heart disease. J Mol Cell Cardiol (2010) 1.11
Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging. J Gerontol A Biol Sci Med Sci (2012) 1.09
Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice. Antioxid Redox Signal (2011) 1.08
Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases. Front Immunol (2014) 1.04
Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress? Exp Diabetes Res (2012) 1.02
Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function. Circulation (2015) 0.99
Thioredoxin 1 enhances neovascularization and reduces ventricular remodeling during chronic myocardial infarction: a study using thioredoxin 1 transgenic mice. J Mol Cell Cardiol (2010) 0.98
Oxidative stress in severe acute illness. Redox Biol (2015) 0.95
Diabetic cardiomyopathy and its mechanisms: Role of oxidative stress and damage. J Diabetes Investig (2014) 0.94
Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol A Biol Sci Med Sci (2012) 0.92
Oxidative stress in heart failure: what are we missing? Am J Med Sci (2011) 0.92
Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease. Vasc Med (2012) 0.89
Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol (2014) 0.87
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. Cardiovasc Diabetol (2015) 0.86
The protective effect of microRNA-320 on left ventricular remodeling after myocardial ischemia-reperfusion injury in the rat model. Int J Mol Sci (2014) 0.86
Redox balance dynamically regulates vascular growth and remodeling. Semin Cell Dev Biol (2012) 0.85
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis. Diabetes (2013) 0.84
Application of recombinant thioredoxin1 for treatment of heart disease. J Mol Cell Cardiol (2010) 0.83
Glutaredoxin-1 overexpression enhances neovascularization and diminishes ventricular remodeling in chronic myocardial infarction. PLoS One (2012) 0.82
Prenatal exposure to lipopolysaccharide results in myocardial remodelling in adult murine offspring. J Inflamm (Lond) (2013) 0.81
PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion. Oncol Lett (2013) 0.80
Interacting with thioredoxin-1--disease or no disease? Antioxid Redox Signal (2012) 0.80
Epalrestat increases glutathione, thioredoxin, and heme oxygenase-1 by stimulating Nrf2 pathway in endothelial cells. Redox Biol (2014) 0.77
Cell stress proteins in atherothrombosis. Oxid Med Cell Longev (2012) 0.77
Oxidative stress contributes to the impaired sonic hedgehog pathway in type 1 diabetic mice with myocardial infarction. Exp Ther Med (2015) 0.75
Modulation of signaling mechanisms in the heart by thioredoxin 1. Free Radic Biol Med (2016) 0.75
Xiaokening stimulates endothelial nitric oxide release in diabetic rats. Singapore Med J (2015) 0.75
HECT-Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin-Interacting Protein and Ameliorates Reactive Oxygen Species-Induced Cardiotoxicity. J Am Heart Assoc (2016) 0.75
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J (1998) 9.36
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med (2001) 5.38
Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol (2003) 5.34
Diabetic cardiomyopathy: the search for a unifying hypothesis. Circ Res (2006) 3.27
Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res (1992) 3.22
Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am J Pathol (1999) 2.83
The ERK cascade: a prototype of MAPK signaling. Mol Biotechnol (2005) 2.45
Abnormal angiogenesis in diabetes mellitus. Med Res Rev (2003) 2.41
Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophys Acta (2008) 2.31
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. J Clin Invest (2003) 2.19
Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation (1999) 1.93
Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med (2007) 1.90
Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor. J Mol Cell Cardiol (2005) 1.59
Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. Diabetes (2008) 1.57
Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J Biol Chem (2000) 1.41
The heme-heme oxygenase system: a molecular switch in wound healing. Blood (2003) 1.39
Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion. Diabetes (2005) 1.37
Heme oxygenase-1 promotes neovascularization in ischemic heart by coinduction of VEGF and SDF-1. J Mol Cell Cardiol (2008) 1.29
Oxidative stress as a therapeutic target in diabetes: revisiting the controversy. Diabetes Metab (2003) 1.29
Adenovirus-mediated VEGF(165) gene transfer enhances wound healing by promoting angiogenesis in CD1 diabetic mice. Gene Ther (2002) 1.26
Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1. J Cell Mol Med (2008) 1.21
Oxidative stress as the leading cause of acute myocardial infarction in diabetics. Cardiovasc Drug Rev (2006) 1.17
Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species. Arch Biochem Biophys (2005) 1.15
Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function. FASEB J (2006) 1.09
Thioredoxin facilitates the induction of heme oxygenase-1 in response to inflammatory mediators. J Biol Chem (2000) 1.08
Thioredoxin1 upregulates mitochondrial proteins related to oxidative phosphorylation and TCA cycle in the heart. Antioxid Redox Signal (2006) 1.04
Coronary artery disease and coronary artery bypass grafting in diabetic patients aged > or = 65 years (report from the Coronary Artery Surgery Study [CASS] Registry). Am J Cardiol (1994) 1.02
A novel promoter sequence is involved in the oxidative stress-induced expression of the adult T-cell leukemia-derived factor (ADF)/human thioredoxin (Trx) gene. Nucleic Acids Res (1996) 0.94
Redox regulation by thioredoxin in cardiovascular diseases. Antioxid Redox Signal (2003) 0.91
Modulation of the thioredoxin system during inflammatory responses and its effect on heme oxygenase-1 expression. Antioxid Redox Signal (2002) 0.90
From oxygen sensing to heart failure: role of thioredoxin. Antioxid Redox Signal (2007) 0.86
Thioredoxin-1 gene delivery induces heme oxygenase-1 mediated myocardial preservation after chronic infarction in hypertensive rats. Am J Hypertens (2008) 0.83
Diastolic function and type 1 diabetes. Diabetes Care (2004) 0.81
High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A (2005) 6.52
Transcriptome sequencing of malignant pleural mesothelioma tumors. Proc Natl Acad Sci U S A (2008) 4.75
c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions. Cancer Res (2003) 3.39
c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev (2003) 2.81
Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat. J Mol Cell Cardiol (2006) 1.94
Angiogenic signal triggered by ischemic stress induces myocardial repair in rat during chronic infarction. J Mol Cell Cardiol (2004) 1.93
Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med (2007) 1.90
Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells. Cancer Res (2002) 1.84
Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice. Am J Physiol Heart Circ Physiol (2003) 1.75
Potentiation of a survival signal in the ischemic heart by resveratrol through p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1/cAMP response element-binding protein signaling. J Pharmacol Exp Ther (2006) 1.71
Retracted Redox regulation of angiotensin II preconditioning of the myocardium requires MAP kinase signaling. J Mol Cell Cardiol (2006) 1.70
Resveratrol-mediated activation of cAMP response element-binding protein through adenosine A3 receptor by Akt-dependent and -independent pathways. J Pharmacol Exp Ther (2005) 1.62
Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proc Natl Acad Sci U S A (2002) 1.60
Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor. J Mol Cell Cardiol (2005) 1.59
Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning. Circulation (2004) 1.58
Resveratrol in cardioprotection: a therapeutic promise of alternative medicine. Mol Interv (2006) 1.48
Glycogen synthase kinase-3beta/beta-catenin promotes angiogenic and anti-apoptotic signaling through the induction of VEGF, Bcl-2 and survivin expression in rat ischemic preconditioned myocardium. J Mol Cell Cardiol (2005) 1.32
Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1. J Cell Mol Med (2008) 1.21
Cardiac genomic response following preconditioning stimulus. Cardiovasc Res (2006) 1.18
Coordinated induction of iNOS-VEGF-KDR-eNOS after resveratrol consumption: a potential mechanism for resveratrol preconditioning of the heart. Vascul Pharmacol (2005) 1.16
Resveratrol: a promising agent in promoting cardioprotection against coronary heart disease. Can J Physiol Pharmacol (2009) 1.16
Thioredoxin redox signaling in the ischemic heart: an insight with transgenic mice overexpressing Trx1. J Mol Cell Cardiol (2003) 1.13
Retracted Pharmacological preconditioning with resveratrol: role of nitric oxide. Am J Physiol Heart Circ Physiol (2002) 1.13
Second generation sequencing of the mesothelioma tumor genome. PLoS One (2010) 1.12
Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1. Cell Biochem Biophys (2006) 1.12
Diabetes, oxidative stress, molecular mechanism, and cardiovascular disease--an overview. Toxicol Mech Methods (2012) 1.11
Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer. Anticancer Res (2004) 1.11
Redox regulation of ischemic preconditioning is mediated by the differential activation of caveolins and their association with eNOS and GLUT-4. Am J Physiol Heart Circ Physiol (2007) 1.11
Pharmacological preconditioning with resveratrol: role of CREB-dependent Bcl-2 signaling via adenosine A3 receptor activation. Am J Physiol Heart Circ Physiol (2004) 1.09
Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice. Antioxid Redox Signal (2011) 1.08
Retracted Cardioprotection with palm tocotrienol: antioxidant activity of tocotrienol is linked with its ability to stabilize proteasomes. Am J Physiol Heart Circ Physiol (2005) 1.08
STAT signaling in ischemic heart: a role of STAT5A in ischemic preconditioning. Am J Physiol Heart Circ Physiol (2003) 1.07
Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma. J Natl Cancer Inst (2009) 1.06
Preconditioning potentiates redox signaling and converts death signal into survival signal. Arch Biochem Biophys (2003) 1.06
Pharmacological preconditioning with resveratrol: an insight with iNOS knockout mice. Am J Physiol Heart Circ Physiol (2002) 1.06
Cardioprotection with alcohol: role of both alcohol and polyphenolic antioxidants. Ann N Y Acad Sci (2002) 1.05
Redox regulation of angiotensin II signaling in the heart. J Cell Mol Med (2004) 1.04
Akt/FOXO3a/SIRT1-mediated cardioprotection by n-tyrosol against ischemic stress in rat in vivo model of myocardial infarction: switching gears toward survival and longevity. J Agric Food Chem (2008) 1.04
Retracted Ischemic preconditioning involves dual cardio-protective axes with p38MAPK as upstream target. J Mol Cell Cardiol (2007) 1.03
MK2-/- gene knockout mouse hearts carry anti-apoptotic signal and are resistant to ischemia reperfusion injury. J Mol Cell Cardiol (2004) 1.03
Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma. Cancer Chemother Pharmacol (2007) 1.01
Strategic targets to induce neovascularization by resveratrol in hypercholesterolemic rat myocardium: role of caveolin-1, endothelial nitric oxide synthase, hemeoxygenase-1, and vascular endothelial growth factor. Free Radic Biol Med (2008) 0.98
Niacin bound chromium treatment induces myocardial Glut-4 translocation and caveolar interaction via Akt, AMPK and eNOS phosphorylation in streptozotocin induced diabetic rats after ischemia-reperfusion injury. Biochim Biophys Acta (2008) 0.98
Thioredoxin 1 enhances neovascularization and reduces ventricular remodeling during chronic myocardial infarction: a study using thioredoxin 1 transgenic mice. J Mol Cell Cardiol (2010) 0.98
DNA copy number evolution in Drosophila cell lines. Genome Biol (2014) 0.97
Retracted Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis. J Mol Cell Cardiol (2007) 0.96
Upregulation of myocardial 11S-activated proteasome in experimental hyperglycemia. J Mol Cell Cardiol (2008) 0.96
Hypolipidaemic effect of chemically different mucilages in rats: a comparative study. Br J Nutr (2006) 0.95
Postischemic deactivation of cardiac aldose reductase: role of glutathione S-transferase P and glutaredoxin in regeneration of reduced thiols from sulfenic acids. J Biol Chem (2010) 0.95
Potential candidates for ischemic preconditioning-associated vascular growth pathways revealed by antibody array. Am J Physiol Heart Circ Physiol (2005) 0.95
Mesenchymal stem cell: present challenges and prospective cellular cardiomyoplasty approaches for myocardial regeneration. Antioxid Redox Signal (2009) 0.94
Niacin-bound chromium enhances myocardial protection from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol (2006) 0.94
VEGFR1 (Flt-1+/-) gene knockout leads to the disruption of VEGF-mediated signaling through the nitric oxide/heme oxygenase pathway in ischemic preconditioned myocardium. Free Radic Biol Med (2007) 0.94
Retracted Ischemic preconditioning triggers nuclear translocation of thioredoxin and its interaction with Ref-1 potentiating a survival signal through the PI-3-kinase-Akt pathway. Antioxid Redox Signal (2006) 0.92
Hypoxic preconditioning triggers myocardial angiogenesis: a novel approach to enhance contractile functional reserve in rat with myocardial infarction. J Mol Cell Cardiol (2002) 0.92
Retracted Role of glutaredoxin-1 in cardioprotection: an insight with Glrx1 transgenic and knockout animals. J Mol Cell Cardiol (2007) 0.91
Secoisolariciresinol diglucoside: relevance to angiogenesis and cardioprotection against ischemia-reperfusion injury. J Pharmacol Exp Ther (2006) 0.91