PubRank

Nicholas J Timpson

Author PubWeight™ 346.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007 37.88
2 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
3 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007 32.97
4 Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008 25.83
5 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
6 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
7 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
8 Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008 15.94
9 A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet 2007 6.87
10 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
11 The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012 4.87
12 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
13 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 2013 4.71
14 Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med 2011 3.94
15 The UK10K project identifies rare variants in health and disease. Nature 2015 3.89
16 Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes 2008 3.76
17 Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest 2008 3.51
18 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
19 Using multiple genetic variants as instrumental variables for modifiable risk factors. Stat Methods Med Res 2011 2.83
20 A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet 2012 2.60
21 Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts. BMJ 2013 2.41
22 Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet 2013 2.36
23 Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet 2010 2.30
24 Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable. PLoS Med 2008 2.16
25 Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet 2010 2.15
26 The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach. PLoS Med 2012 2.09
27 Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream. PLoS Med 2008 1.95
28 New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet 2012 1.90
29 Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. PLoS Genet 2009 1.89
30 Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults. J Intern Med 2011 1.89
31 Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. PLoS Med 2010 1.88
32 A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Nat Genet 2013 1.85
33 Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst 2012 1.83
34 Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet 2011 1.82
35 Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis 2009 1.78
36 Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position. Am J Hum Genet 2012 1.73
37 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
38 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
39 Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity (Silver Spring) 2014 1.65
40 Association between C-reactive protein genotype, circulating levels, and aortic pulse wave velocity. Hypertension 2008 1.64
41 Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet 2011 1.60
42 Type 2 diabetes risk alleles are associated with reduced size at birth. Diabetes 2009 1.58
43 WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet 2012 1.55
44 Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors. Eur J Epidemiol 2015 1.51
45 Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet 2012 1.51
46 Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet 2012 1.49
47 Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. PLoS Genet 2010 1.40
48 Genome-wide population-based association study of extremely overweight young adults--the GOYA study. PLoS One 2011 1.34
49 A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. Am J Hum Genet 2010 1.32
50 Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children. Diabetes 2011 1.31
51 Severe obesity in young women and reproductive health: the Danish National Birth Cohort. PLoS One 2009 1.28
52 Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease. Genome Med 2009 1.25
53 Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis. Am J Med Genet B Neuropsychiatr Genet 2008 1.24
54 Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Hum Mol Genet 2013 1.19
55 Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Hum Mol Genet 2013 1.17
56 A powerful approach to sub-phenotype analysis in population-based genetic association studies. Genet Epidemiol 2010 1.16
57 Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. J Bone Miner Res 2013 1.16
58 Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data. Nicotine Tob Res 2009 1.11
59 Adult height variants affect birth length and growth rate in children. Hum Mol Genet 2011 1.11
60 Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone. PLoS Genet 2010 1.10
61 Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study. PLoS One 2008 1.09
62 Dietary energy density affects fat mass in early adolescence and is not modified by FTO variants. PLoS One 2009 1.07
63 Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet 2013 1.06
64 Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI. Eur J Hum Genet 2009 1.02
65 Melanesian blond hair is caused by an amino acid change in TYRP1. Science 2012 1.01
66 Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence. Mol Autism 2014 1.00
67 Association of a body mass index genetic risk score with growth throughout childhood and adolescence. PLoS One 2013 0.96
68 Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet 2013 0.94
69 Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. PLoS Genet 2013 0.94
70 Genome-wide association study identifies loci affecting blood copper, selenium and zinc. Hum Mol Genet 2013 0.93
71 Common variation in the WNK1 gene and blood pressure in childhood: the Avon Longitudinal Study of Parents and Children. Hypertension 2008 0.93
72 Genome-wide association scan allowing for epistasis in type 2 diabetes. Ann Hum Genet 2010 0.93
73 Common variation contributes to the genetic architecture of social communication traits. Mol Autism 2013 0.92
74 A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement. Eur J Endocrinol 2011 0.89
75 Validation of dual energy X-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population. PLoS One 2012 0.89
76 Adiponectin and its association with bone mass accrual in childhood. J Bone Miner Res 2010 0.89
77 Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort. J Allergy Clin Immunol 2012 0.89
78 The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study. Clin Sci (Lond) 2011 0.87
79 Vitamin B-12 status during pregnancy and child's IQ at age 8: a Mendelian randomization study in the Avon longitudinal study of parents and children. PLoS One 2012 0.86
80 Coordinated genetic scaling of the human eye: shared determination of axial eye length and corneal curvature. Invest Ophthalmol Vis Sci 2013 0.84
81 Genetic influences on trajectories of systolic blood pressure across childhood and adolescence. Circ Cardiovasc Genet 2013 0.84
82 A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor α gene as a quantitative trait locus for eye size in white Europeans. Mol Vis 2013 0.84
83 The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects. Am J Med Genet B Neuropsychiatr Genet 2010 0.84
84 Genome-wide association study identifies four loci associated with eruption of permanent teeth. PLoS Genet 2011 0.84
85 Evaluation of seven common lipid associated loci in a large Indian sib pair study. Lipids Health Dis 2012 0.82
86 Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT. J Bone Miner Res 2014 0.82
87 Letter by Timpson et al regarding article, "Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level". Circulation 2006 0.82
88 Association of maternal smoking with child cotinine levels. Nicotine Tob Res 2013 0.82
89 Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2013 0.81
90 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.81
91 Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Hum Genet 2014 0.79
92 Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nat Commun 2016 0.78
93 Erratum: Whole-genome sequence-based analysis of thyroid function. Nat Commun 2015 0.77
94 International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents. Circ Cardiovasc Genet 2016 0.77
95 Does a short breastfeeding period protect from FTO-induced adiposity in children? Int J Pediatr Obes 2010 0.76
96 Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence. Hum Genet 2014 0.75
97 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.75
98 Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nat Commun 2015 0.75