Published in J Cell Sci on March 09, 2010
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Ezrin-radixin-moesin (ERM)-binding phosphoprotein 50 organizes ERM proteins at the apical membrane of polarized epithelia. Proc Natl Acad Sci U S A (2004) 2.31
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Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides. Mol Biol Cell (1999) 1.91
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Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science (2005) 1.81
The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells. Breast Cancer Res (2005) 1.76
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RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts. Mol Biol Cell (1998) 1.62
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Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function. Oncogene (2007) 1.54
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C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton. Biochem Biophys Res Commun (1998) 1.50
Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes. EMBO J (2000) 1.47
NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer. Oncogene (2004) 1.44
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The receptor tyrosine phosphatase Dlar and integrins organize actin filaments in the Drosophila follicular epithelium. Curr Biol (2001) 1.40
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Hierarchy of merlin and ezrin N- and C-terminal domain interactions in homo- and heterotypic associations and their relationship to binding of scaffolding proteins EBP50 and E3KARP. J Biol Chem (2000) 1.36
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Distinct cell type-specific expression of scaffolding proteins EBP50 and E3KARP: EBP50 is generally expressed with ezrin in specific epithelia, whereas E3KARP is not. Eur J Cell Biol (2002) 1.30
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Epithelial barriers, compartmentation, and cancer. Sci STKE (2004) 1.19
Regulation of the renal brush border membrane Na(+)-H+ exchanger. Annu Rev Physiol (1993) 1.17
Ezrin-radixin-moesin-binding phosphoprotein 50 is expressed at the apical membrane of rat liver epithelia. Hepatology (2001) 1.16
Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors. J Cell Biol (2005) 1.14
Abnormal ezrin localization is associated with clinicopathological features in invasive breast carcinomas. Breast Cancer Res Treat (2006) 1.12
Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM). Genes Cells (2005) 1.07
Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase. J Cell Biol (2006) 1.07
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The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50. Biochemistry (2009) 1.01
Establishment and maintenance of parasegmental compartments. Development (2001) 0.97
A systematic screen for dominant second-site modifiers of Merlin/NF2 phenotypes reveals an interaction with blistered/DSRF and scribbler. Genetics (2001) 0.95
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The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling. Curr Biol (2006) 2.37
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Cell (2011) 2.34
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature (2003) 2.32
Ral GTPases regulate exocyst assembly through dual subunit interactions. J Biol Chem (2003) 2.23
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation. Mol Cell (2011) 2.13
Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis. Nat Cell Biol (2011) 1.96
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hPOC5 is a centrin-binding protein required for assembly of full-length centrioles. J Cell Biol (2009) 1.49
An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation. PLoS Biol (2009) 1.48
Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway. Dev Cell (2011) 1.43
Understanding ERM proteins--the awesome power of genetics finally brought to bear. Curr Opin Cell Biol (2006) 1.40
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Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J Cell Biol (2013) 1.28
Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling. Dev Cell (2012) 1.26
A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery. Dev Cell (2012) 1.22
Rho1 regulates apoptosis via activation of the JNK signaling pathway at the plasma membrane. J Cell Biol (2010) 1.16
The multifunctional protein PEA-15 is involved in the control of apoptosis and cell cycle in astrocytes. Biochem Pharmacol (2003) 1.13
Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase. J Cell Biol (2006) 1.07
Rab6 and the secretory pathway affect oocyte polarity in Drosophila. Development (2007) 1.05
The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes. Mol Biol Cell (2010) 1.02
Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants. Proc Natl Acad Sci U S A (2010) 0.98
Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. Development (2010) 0.94
Ezrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins. Mol Biol Cell (2012) 0.93
Interaction between Polo and BicD proteins links oocyte determination and meiosis control in Drosophila. Development (2006) 0.93
Analysis of protein dynamics within the septate junction reveals a highly stable core protein complex that does not include the basolateral polarity protein Discs large. J Cell Sci (2011) 0.93
Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin. Mol Biol Cell (2013) 0.85
Macroglobulin complement-related encodes a protein required for septate junction organization and paracellular barrier function in Drosophila. Development (2014) 0.82
DLG1/SAP97 modulates transforming growth factor alpha bioavailability. Biochim Biophys Acta (2008) 0.80
FERMing up the plasma membrane. Dev Cell (2008) 0.79
Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation. J Cell Biol (2013) 0.79
Preparation of soluble GST fusion proteins. Cold Spring Harb Protoc (2009) 0.77
A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6. PLoS One (2013) 0.76
Antibody staining of Drosophila tissues--helpful hints. CSH Protoc (2008) 0.75
Dot blot assay for determining fusion protein antiserum quality. Cold Spring Harb Protoc (2011) 0.75
[Molecular network for the transport of intracellular vesicles from cell center to periphery]. Med Sci (Paris) (2012) 0.75
Preparation of insoluble GST fusion proteins. Cold Spring Harb Protoc (2009) 0.75
The transmembrane protein Crumbs displays complex dynamics during follicular morphogenesis and is regulated competitively by Moesin and aPKC. Development (2015) 0.75
Determining fusion protein antiserum quality by staining of transfected Drosophila S2 cultured cells. Cold Spring Harb Protoc (2011) 0.75
Streamlined protocol for antibody staining of large numbers of samples in Drosophila. CSH Protoc (2008) 0.75