PubRank

Jack E Dixon

Author PubWeight™ 148.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol 2007 13.99
2 Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Science 2003 3.81
3 Identification of a bacterial type III effector family with G protein mimicry functions. Cell 2006 3.47
4 Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A 2008 3.20
5 Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vector. Science 2002 3.10
6 Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol 2002 2.93
7 Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A 2003 2.92
8 Widespread dynamic DNA methylation in response to biotic stress. Proc Natl Acad Sci U S A 2012 2.90
9 A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis. Cell 2002 2.75
10 The fic domain: regulation of cell signaling by adenylylation. Mol Cell 2009 2.73
11 Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science 2012 2.55
12 Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Mol Cell 2005 2.36
13 MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A 2007 2.28
14 Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe 2008 2.21
15 MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A 2007 2.19
16 Overview of the Alliance for Cellular Signaling. Nature 2002 2.15
17 Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol 2006 2.09
18 Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J Biol Chem 2006 2.04
19 Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab 2011 1.97
20 Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proc Natl Acad Sci U S A 2005 1.90
21 A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A 2008 1.85
22 Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem Sci 2005 1.81
23 A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A 2007 1.80
24 Secreted protein kinases. Trends Biochem Sci 2012 1.79
25 A unique carbohydrate binding domain targets the lafora disease phosphatase to glycogen. J Biol Chem 2001 1.78
26 The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem 2007 1.72
27 Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. Mol Cell 2006 1.71
28 The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol 2007 1.67
29 PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem 2001 1.66
30 The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J Cell Biol 2007 1.66
31 PTEN. Annu Rev Biochem 2014 1.62
32 PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease. Trends Cell Biol 2002 1.62
33 The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases. J Biol Chem 2003 1.61
34 Functions of the Yersinia effector proteins in inhibiting host immune responses. Curr Opin Microbiol 2005 1.57
35 Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem 2007 1.57
36 Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc Natl Acad Sci U S A 2003 1.54
37 Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase. Proc Natl Acad Sci U S A 2003 1.53
38 Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem 2009 1.50
39 Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci 2009 1.50
40 Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome. Mol Cell 2003 1.46
41 Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol 2010 1.44
42 Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem 2009 1.38
43 The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc Natl Acad Sci U S A 2003 1.38
44 Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A 2014 1.35
45 Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease. J Biol Chem 2001 1.35
46 Interactions of bacterial effector proteins with host proteins. Curr Opin Immunol 2007 1.33
47 A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev 2007 1.32
48 Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase. Proc Natl Acad Sci U S A 2006 1.30
49 Identification of a molecular target for the Yersinia protein kinase A. Mol Cell 2007 1.29
50 A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem 2004 1.26
51 Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem 2010 1.25
52 Yersinia effectors target mammalian signalling pathways. Cell Microbiol 2002 1.23
53 Voltage-sensing phosphatase: its molecular relationship with PTEN. Physiology (Bethesda) 2011 1.20
54 The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J Biol Chem 2005 1.18
55 Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem 2011 1.17
56 Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem 2011 1.15
57 A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem 2009 1.12
58 UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A 2011 1.09
59 The structure and regulation of myotubularin phosphatases. Curr Opin Struct Biol 2005 1.08
60 Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem 2012 1.08
61 PTEN and myotubularins: families of phosphoinositide phosphatases. Methods Enzymol 2003 1.07
62 The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A 2002 1.04
63 Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med 2013 1.04
64 Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A 2008 0.98
65 Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc Natl Acad Sci U S A 2011 0.98
66 Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades. J Biol Chem 2002 0.98
67 Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem 2008 0.97
68 Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. J Mol Biol 2011 0.97
69 Crystal structure of the Golgi casein kinase. Proc Natl Acad Sci U S A 2013 0.97
70 Phosphoinositide phosphatases: emerging roles as voltage sensors? Mol Interv 2005 0.95
71 Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci 2010 0.94
72 A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem 2003 0.92
73 Pharmacological targeting of the mitochondrial phosphatase PTPMT1. J Pharmacol Exp Ther 2010 0.92
74 Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem 2001 0.91
75 Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev 2014 0.86
76 The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Mol Cancer 2006 0.86
77 Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET. Methods Enzymol 2009 0.85
78 Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21. Methods Enzymol 2009 0.85
79 YopT is a cysteine protease cleaving Rho family GTPases. Adv Exp Med Biol 2003 0.84
80 Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins. Methods Enzymol 2008 0.83
81 Phosphorylation of substrates destined for secretion by the Fam20 kinases. Biochem Soc Trans 2013 0.83
82 Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem J 2002 0.83
83 Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. FEBS Lett 2005 0.82
84 Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN. FEBS Lett 2004 0.82
85 Microbiology. Bacteria seize control by acetylating host proteins. Science 2006 0.82
86 The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons. Neuron 2013 0.81
87 Assaying phosphoinositide phosphatases. Methods Mol Biol 2004 0.80
88 Recognition of the protein kinase AVRPPHB SUSCEPTIBLE1 by the disease resistance protein RESISTANCE TO PSEUDOMONAS SYRINGAE5 is dependent on s-acylation and an exposed loop in AVRPPHB SUSCEPTIBLE1. Plant Physiol 2013 0.80
89 RNA interference in cultured Drosophila cells. Curr Protoc Mol Biol 2004 0.78
90 Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Mol Cell Proteomics 2014 0.78
91 Response to Wang et al.: Secreted protein kinases? Trends Biochem Sci 2013 0.77
92 Subversion of myosin function by E. coli. Dev Cell 2008 0.77
93 Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica. J Biol Chem 2013 0.76
94 Glycogen synthase: an old enzyme with a new trick. Cell Metab 2011 0.75