Published in Hered Cancer Clin Pract on May 15, 2006
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Up-regulation of DNA methyltransferase 3B expression in endometrial cancers. Gynecol Oncol (2005) 0.99
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet (2011) 6.77
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res (2006) 3.81
Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med (2008) 3.76
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum Mol Genet (2008) 2.33
Planning the human variome project: the Spain report. Hum Mutat (2009) 2.22
Innate immune activation in neutrophilic asthma and bronchiectasis. Thorax (2006) 2.18
Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers. Int J Cancer (2012) 2.15
The NOD2 3020insC mutation and the risk of colorectal cancer. Cancer Res (2004) 2.01
Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med (2007) 1.91
Genome-wide association study identifies a common variant associated with risk of endometrial cancer. Nat Genet (2011) 1.84
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet (2012) 1.81
A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting. J Mol Diagn (2009) 1.76
The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Hum Mol Genet (2010) 1.73
Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk. Cancer Epidemiol (2010) 1.63
Relative frequency and morphology of cancers in STK11 mutation carriers. Gastroenterology (2004) 1.62
Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53. Int J Cancer (2006) 1.60
Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet (2010) 1.57
Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples. J Allergy Clin Immunol (2011) 1.57
MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood. PLoS One (2010) 1.49
Potential association of vitamin D receptor polymorphism Taq1 with multiple sclerosis. Mult Scler (2011) 1.47
BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer. Breast Cancer Res Treat (2011) 1.46
Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin. Clin Cancer Res (2008) 1.44
Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome. J Med Genet (2010) 1.42
Genome-wide association meta-analysis identifies new endometriosis risk loci. Nat Genet (2012) 1.42
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Mutation analysis of MLH1 and MSH2 genes performed by denaturing high-performance liquid chromatography. J Biochem Biophys Methods (2002) 1.30
Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Ann Neurol (2013) 1.30
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Direct integrin alphavbeta6-ERK binding: implications for tumour growth. Oncogene (2002) 1.25
Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists. BMC Cancer (2010) 1.24
Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma. Am J Respir Crit Care Med (2005) 1.24
How to use an article about genetic association: A: Background concepts. JAMA (2009) 1.21
Parental prenatal smoking and risk of childhood acute lymphoblastic leukemia. Am J Epidemiol (2011) 1.19
P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation. BMC Cancer (2011) 1.18
Preliminary investigation of gene expression profiles in peripheral blood lymphocytes in schizophrenia. Schizophr Res (2006) 1.18
Altered gene expression in the superior temporal gyrus in schizophrenia. BMC Genomics (2008) 1.17
Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nat Genet (2010) 1.16
Decreased expression of key tumour suppressor microRNAs is associated with lymph node metastases in triple negative breast cancer. BMC Cancer (2014) 1.16
Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One (2013) 1.16
A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes. BMC Cancer (2011) 1.12
An X-linked haplotype of Neandertal origin is present among all non-African populations. Mol Biol Evol (2011) 1.11
Capturing all disease-causing mutations for clinical and research use: toward an effortless system for the Human Variome Project. Genet Med (2009) 1.10
CDKN2A common variants and their association with melanoma risk: a population-based study. Cancer Res (2005) 1.08
Transcriptome sequencing revealed significant alteration of cortical promoter usage and splicing in schizophrenia. PLoS One (2012) 1.07
Cytokine responses and sudden infant death syndrome: genetic, developmental, and environmental risk factors. J Leukoc Biol (2005) 1.07
IGF1 is a modifier of disease risk in hereditary non-polyposis colorectal cancer. Int J Cancer (2008) 1.06
Microarrays--identifying molecular portraits for prostate tumors with different Gleason patterns. Methods Mol Med (2008) 1.05
The RAD51 135 G>C polymorphism modifies breast cancer and ovarian cancer risk in Polish BRCA1 mutation carriers. Cancer Epidemiol Biomarkers Prev (2007) 1.03
Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation. PLoS One (2011) 1.02
How to use an article about genetic association: C: What are the results and will they help me in caring for my patients? JAMA (2009) 1.02
Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations. Int J Cancer (2005) 1.02
Genome-wide association study identifies a possible susceptibility locus for endometrial cancer. Cancer Epidemiol Biomarkers Prev (2012) 1.02
Phenotype-genotype correlations in a series of wolfram syndrome families. Diabetes Care (2004) 1.01
Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet Oncol (2012) 1.01
Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. Hum Mol Genet (2013) 1.01
A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis. PLoS One (2010) 1.00
CDKN2A common variant and multi-organ cancer risk--a population-based study. Int J Cancer (2006) 0.99
Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring. Int J Cancer (2010) 0.98
Methylenetetrahydrofolate reductase polymorphisms modify BRCA1-associated breast and ovarian cancer risks. Breast Cancer Res Treat (2006) 0.98
BRCA1-associated breast and ovarian cancer risks in Poland: no association with commonly studied polymorphisms. Breast Cancer Res Treat (2009) 0.95
Oncostatin M (OSM) is increased in asthma with incompletely reversible airflow obstruction. Exp Lung Res (2009) 0.95
Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer. Int J Cancer (2008) 0.95
Altered gene expression in the amygdala in schizophrenia: up-regulation of genes located in the cytomatrix active zone. Mol Cell Neurosci (2005) 0.94
Polymorphisms in TP53 and MDM2 combined are associated with high grade endometrial cancer. Gynecol Oncol (2009) 0.94
Whole genome amplification and its impact on CGH array profiles. BMC Res Notes (2008) 0.94
MDM2 SNP309 T>G alone or in combination with the TP53 R72P polymorphism does not appear to influence disease expression and age of diagnosis of colorectal cancer in HNPCC patients. Int J Cancer (2007) 0.94
Interleukin-10 and sudden infant death syndrome. FEMS Immunol Med Microbiol (2004) 0.93
The relative mRNA expression of p53 isoforms in breast cancer is associated with clinical features and outcome. Carcinogenesis (2013) 0.93
Genome-wide association study of endometrial cancer in E2C2. Hum Genet (2013) 0.93
Can selenium levels act as a marker of colorectal cancer risk? BMC Cancer (2013) 0.93
Immune responses of airway neutrophils are impaired in asthma. Exp Lung Res (2009) 0.93
Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk. BMC Cancer (2008) 0.92
Altered expression of regulator of G-protein signalling 4 (RGS4) mRNA in the superior temporal gyrus in schizophrenia. Schizophr Res (2006) 0.92
Comparison of genomic abnormalities between BRCAX and sporadic breast cancers studied by comparative genomic hybridization. Int J Cancer (2005) 0.92
Toll-like receptor (TLR) and nucleosome-binding oligomerization domain (NOD) gene polymorphisms and endometrial cancer risk. BMC Cancer (2010) 0.92
Buccal DNA collection: comparison of buccal swabs with FTA cards. Cancer Epidemiol Biomarkers Prev (2006) 0.91
Prevalence of BRCA1 and BRCA2 germline mutations in patients with triple-negative breast cancer. Breast Cancer Res Treat (2015) 0.91
IL6 G-174C associated with sudden infant death syndrome in a Caucasian Australian cohort. Hum Immunol (2006) 0.91
Germline mutation and large deletion analysis of the CDKN2A and ARF genes in families with multiple melanoma or an aggregation of malignant melanoma and breast cancer. Int J Cancer (2004) 0.91
Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke (2012) 0.91
DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome. Cancer Epidemiol (2011) 0.90
Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells. J Psychiatr Res (2012) 0.90
Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Hum Genet (2014) 0.89
Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age. Int J Cancer (2009) 0.89
The VEGF_936_C>T 3'UTR polymorphism reduces BRCA1-associated breast cancer risk in Polish women. Cancer Lett (2008) 0.89
Maternal use of folic acid and other supplements and risk of childhood brain tumors. Cancer Epidemiol Biomarkers Prev (2012) 0.89
Prevalence of the NOD2 3020insC mutation in aggregations of breast and lung cancer. Breast Cancer Res Treat (2006) 0.89
The male excess in sudden infant deaths. Innate Immun (2013) 0.88
Germline mutations in the CHEK2 kinase gene are associated with an increased risk of bladder cancer. Int J Cancer (2008) 0.88
Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population. PLoS One (2011) 0.88
Nucleotide excision repair gene expression after Cisplatin treatment in melanoma. Cancer Res (2010) 0.86
Ethnicity, infection and sudden infant death syndrome. FEMS Immunol Med Microbiol (2004) 0.86
Gene expression profiling in treatment-naive schizophrenia patients identifies abnormalities in biological pathways involving AKT1 that are corrected by antipsychotic medication. Int J Neuropsychopharmacol (2013) 0.86
Frequency of the Common MYH Mutations (G382D and Y165C) in MMR Mutation Positive and Negative HNPCC Patients. Hered Cancer Clin Pract (2005) 0.86
Genetic modifiers of cancer risk in Lynch syndrome: a review. Fam Cancer (2013) 0.85
The 3' untranslated region C > T polymorphism of prohibitin is a breast cancer risk modifier in Polish women carrying a BRCA1 mutation. Breast Cancer Res Treat (2006) 0.85