1
|
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes.
|
J Biol Chem
|
2005
|
1.64
|
2
|
Efficient DNA interstrand cross-link formation from a nucleotide radical.
|
J Am Chem Soc
|
2005
|
1.60
|
3
|
Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.
|
Nucleic Acids Res
|
2006
|
1.51
|
4
|
Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle.
|
Proc Natl Acad Sci U S A
|
2010
|
1.39
|
5
|
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
|
J Am Chem Soc
|
2006
|
1.38
|
6
|
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
|
J Biol Chem
|
2007
|
1.38
|
7
|
DNA interstrand cross-link formation initiated by reaction between singlet oxygen and a modified nucleotide.
|
J Am Chem Soc
|
2005
|
1.37
|
8
|
Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone.
|
J Biol Chem
|
2002
|
1.30
|
9
|
Self-promoted DNA interstrand cross-link formation by an abasic site.
|
J Am Chem Soc
|
2008
|
1.30
|
10
|
Tandem lesions are the major products resulting from a pyrimidine nucleobase radical.
|
J Am Chem Soc
|
2003
|
1.28
|
11
|
Mutagenic effects of 2-deoxyribonolactone in Escherichia coli. An abasic lesion that disobeys the A-rule.
|
Biochemistry
|
2004
|
1.28
|
12
|
Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical.
|
J Am Chem Soc
|
2007
|
1.26
|
13
|
Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link.
|
Biochemistry
|
2009
|
1.23
|
14
|
A comprehensive comparison of DNA replication past 2-deoxyribose and its tetrahydrofuran analog in Escherichia coli.
|
Nucleic Acids Res
|
2004
|
1.22
|
15
|
Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues.
|
J Am Chem Soc
|
2002
|
1.20
|
16
|
Selective detection of 2-deoxyribonolactone in DNA.
|
J Am Chem Soc
|
2005
|
1.18
|
17
|
Effects of the C4'-oxidized abasic site on replication in Escherichia coli. An unusually large deletion is induced by a small lesion.
|
Biochemistry
|
2004
|
1.17
|
18
|
Synthesis and characterization of oligonucleotides containing the c4'-oxidized abasic site produced by bleomycin and other DNA damaging agents.
|
Angew Chem Int Ed Engl
|
2003
|
1.15
|
19
|
Transforming thymidine into a magnetic resonance imaging probe for monitoring gene expression.
|
J Am Chem Soc
|
2013
|
1.15
|
20
|
Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase.
|
Proc Natl Acad Sci U S A
|
2008
|
1.13
|
21
|
Repair of DNA containing Fapy.dG and its beta-C-nucleoside analogue by formamidopyrimidine DNA glycosylase and MutY.
|
Biochemistry
|
2003
|
1.13
|
22
|
Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes.
|
Biochemistry
|
2003
|
1.13
|
23
|
Scope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site.
|
J Am Chem Soc
|
2009
|
1.12
|
24
|
Preparation and analysis of oligonucleotides containing lesions resulting from C5'-oxidation.
|
J Org Chem
|
2005
|
1.12
|
25
|
Fapy.dG instructs Klenow exo(-) to misincorporate deoxyadenosine.
|
J Am Chem Soc
|
2002
|
1.11
|
26
|
Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines.
|
J Am Chem Soc
|
2008
|
1.10
|
27
|
Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases.
|
Biochemistry
|
2007
|
1.08
|
28
|
Use of fluorescence sensors to determine that 2-deoxyribonolactone is the major alkali-labile deoxyribose lesion produced in oxidatively damaged DNA.
|
Angew Chem Int Ed Engl
|
2007
|
1.08
|
29
|
Photochemical generation and reactivity of the 5,6-dihydrouridin-6-yl radical.
|
J Org Chem
|
2009
|
1.06
|
30
|
Studies on the replication of the ring opened formamidopyrimidine, Fapy.dG in Escherichia coli.
|
Biochemistry
|
2007
|
1.06
|
31
|
DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesion.
|
J Am Chem Soc
|
2009
|
1.05
|
32
|
A minor groove binding copper-phenanthroline conjugate produces direct strand breaks via beta-elimination of 2-deoxyribonolactone.
|
J Am Chem Soc
|
2002
|
1.03
|
33
|
DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair.
|
Biochemistry
|
2008
|
1.03
|
34
|
Multinuclear NMR and kinetic analysis of DNA interstrand cross-link formation.
|
J Am Chem Soc
|
2008
|
1.03
|
35
|
Radiosensitization by a modified nucleotide that produces DNA interstrand cross-links under hypoxic conditions.
|
J Am Chem Soc
|
2006
|
1.01
|
36
|
Action of human apurinic endonuclease (Ape1) on C1'-oxidized deoxyribose damage in DNA.
|
DNA Repair (Amst)
|
2003
|
1.00
|
37
|
Product and mechanistic analysis of the reactivity of a C6-pyrimidine radical in RNA.
|
J Am Chem Soc
|
2011
|
0.99
|
38
|
Selective detection and quantification of oxidized abasic lesions in DNA.
|
J Am Chem Soc
|
2007
|
0.99
|
39
|
Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles.
|
J Am Chem Soc
|
2012
|
0.99
|
40
|
Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone.
|
J Am Chem Soc
|
2012
|
0.98
|
41
|
Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.
|
Free Radic Res
|
2012
|
0.97
|
42
|
Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae.
|
Nucleic Acids Res
|
2005
|
0.97
|
43
|
Facile quantification of lesions derived from 2'-deoxyguanosine in DNA.
|
J Am Chem Soc
|
2007
|
0.97
|
44
|
Probing the configurations of formamidopyrimidine lesions Fapy.dA and Fapy.dG in DNA using endonuclease IV.
|
Biochemistry
|
2004
|
0.97
|
45
|
Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks.
|
Biochemistry
|
2010
|
0.97
|
46
|
Independent generation and characterization of a C2'-oxidized abasic site in chemically synthesized oligonucleotides.
|
J Org Chem
|
2004
|
0.96
|
47
|
Replication of an oxidized abasic site in Escherichia coli by a dNTP-stabilized misalignment mechanism that reads upstream and downstream nucleotides.
|
Biochemistry
|
2006
|
0.96
|
48
|
DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2).
|
J Am Chem Soc
|
2007
|
0.96
|
49
|
Evidence for glycosidic bond rotation in a nucleobase peroxyl radical and its effect on tandem lesion formation.
|
J Org Chem
|
2004
|
0.95
|
50
|
Direct strand scission in double stranded RNA via a C5-pyrimidine radical.
|
J Am Chem Soc
|
2012
|
0.94
|
51
|
Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion.
|
J Am Chem Soc
|
2010
|
0.94
|
52
|
Mild generation of 5-(2'-deoxyuridinyl)methyl radical from a phenyl selenide precursor.
|
Org Lett
|
2004
|
0.94
|
53
|
Synthesis of oligonucleotides containing Fapy.dG (N(6)-(2-deoxy-alpha,beta-D-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine) using a 5'-dimethoxytrityl dinucleotide phosphoramidite.
|
J Org Chem
|
2005
|
0.94
|
54
|
Direct strand scission from a nucleobase radical in RNA.
|
J Am Chem Soc
|
2010
|
0.94
|
55
|
Inhibition of short patch and long patch base excision repair by an oxidized abasic site.
|
Biochemistry
|
2010
|
0.93
|
56
|
Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine.
|
Org Lett
|
2012
|
0.93
|
57
|
Synthesis of oligonucleotides and thermal stability of duplexes containing the beta-C-nucleoside analogue of Fapy*dG.
|
Chem Res Toxicol
|
2002
|
0.92
|
58
|
Facile SNP detection using bifunctional, cross-linking oligonucleotide probes.
|
Nucleic Acids Res
|
2008
|
0.92
|
59
|
Fapy.dA induces nucleotide misincorporation translesionally by a DNA polymerase.
|
Angew Chem Int Ed Engl
|
2002
|
0.92
|
60
|
Nucleosome core particle-catalyzed strand scission at abasic sites.
|
Biochemistry
|
2013
|
0.91
|
61
|
Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates.
|
J Am Chem Soc
|
2006
|
0.90
|
62
|
Long patch base excision repair compensates for DNA polymerase β inactivation by the C4'-oxidized abasic site.
|
Biochemistry
|
2010
|
0.90
|
63
|
Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI.
|
Nat Protoc
|
2013
|
0.90
|
64
|
Histone modification via rapid cleavage of C4'-oxidized abasic sites in nucleosome core particles.
|
J Am Chem Soc
|
2013
|
0.89
|
65
|
Interaction of DNA containing Fapy.dA or its C-nucleoside analogues with base excision repair enzymes. Implications for mutagenesis and enzyme inhibition.
|
Biochemistry
|
2002
|
0.89
|
66
|
Synthesis of 5,12-dioxocyclam nickel (II) complexes having quinoxaline substituents at the 6 and 13 positions as potential DNA bis-intercalating and cleaving agents.
|
J Org Chem
|
2003
|
0.88
|
67
|
Protein binding has a large effect on radical mediated DNA damage.
|
J Am Chem Soc
|
2008
|
0.88
|
68
|
DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases.
|
Bioorg Med Chem
|
2012
|
0.87
|
69
|
Excision of formamidopyrimidine lesions by endonucleases III and VIII is not a major DNA repair pathway in Escherichia coli.
|
Nucleic Acids Res
|
2005
|
0.86
|
70
|
Independent generation and study of 5,6-Dihydro-2'-deoxyuridin-6-yl, a member of the major family of reactive intermediates formed in DNA from the effects of gamma-radiolysis.
|
J Org Chem
|
2003
|
0.86
|
71
|
Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.
|
Bioorg Med Chem
|
2011
|
0.86
|
72
|
Photochemical control of RNA structure by disrupting π-stacking.
|
J Am Chem Soc
|
2012
|
0.86
|
73
|
Hydrogen bonding contributes to the selectivity of nucleotide incorporation opposite an oxidized abasic lesion.
|
J Am Chem Soc
|
2008
|
0.85
|
74
|
Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine.
|
Chembiochem
|
2011
|
0.85
|
75
|
The mutagenicity of thymidine glycol in Escherichia coli is increased when it is part of a tandem lesion.
|
Biochemistry
|
2009
|
0.84
|
76
|
Excision of a lyase-resistant oxidized abasic lesion from DNA.
|
Chem Res Toxicol
|
2010
|
0.84
|
77
|
Synthesis of cross-linked DNA containing oxidized abasic site analogues.
|
J Org Chem
|
2014
|
0.83
|
78
|
Gamma-radiolysis and hydroxyl radical produce interstrand cross-links in DNA involving thymidine.
|
Chem Res Toxicol
|
2007
|
0.83
|
79
|
5,6-Dihydropyrimidine peroxyl radical reactivity in DNA.
|
J Am Chem Soc
|
2014
|
0.83
|
80
|
DNA double strand cleavage via interstrand hydrogen atom abstraction.
|
J Am Chem Soc
|
2013
|
0.83
|
81
|
Synthesis and analysis of oligonucleotides containing abasic site analogues.
|
J Org Chem
|
2008
|
0.82
|
82
|
DNA polymerase λ inactivation by oxidized abasic sites.
|
Biochemistry
|
2013
|
0.82
|
83
|
Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA.
|
Chem Res Toxicol
|
2010
|
0.82
|
84
|
Mechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates.
|
Nucleic Acids Res
|
2005
|
0.82
|
85
|
The effect of the 2-amino group of 7,8-dihydro-8-oxo-2'-deoxyguanosine on translesion synthesis and duplex stability.
|
Nucleic Acids Res
|
2005
|
0.81
|
86
|
Probing interactions between lysine residues in histone tails and nucleosomal DNA via product and kinetic analysis.
|
ACS Chem Biol
|
2014
|
0.81
|
87
|
Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase.
|
J Am Chem Soc
|
2009
|
0.81
|
88
|
Deconvoluting the reactivity of two intermediates formed from modified pyrimidines.
|
Org Lett
|
2013
|
0.81
|
89
|
DNA damage and interstrand cross-link formation upon irradiation of aryl iodide C-nucleotide analogues.
|
J Org Chem
|
2010
|
0.80
|
90
|
Independent generation and reactivity of uridin-2'-yl radical.
|
J Org Chem
|
2014
|
0.80
|
91
|
Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues.
|
Environ Mol Mutagen
|
2002
|
0.80
|
92
|
Quantification of 8-oxodGuo lesions in double-stranded DNA using a photoelectrochemical DNA sensor.
|
Anal Chem
|
2012
|
0.80
|
93
|
DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG.
|
Bioorg Med Chem
|
2008
|
0.79
|
94
|
DNA damage by histone radicals in nucleosome core particles.
|
J Am Chem Soc
|
2014
|
0.79
|
95
|
Preparation and analysis of oligonucleotides containing the c4'-oxidized abasic site and related mechanistic probes.
|
J Org Chem
|
2005
|
0.79
|
96
|
Nucleotide excision repair of chemically stabilized analogues of DNA interstrand cross-links produced from oxidized abasic sites.
|
Biochemistry
|
2014
|
0.78
|
97
|
Hole migration is the major pathway involved in alkali-labile lesion formation in DNA by the direct effect of ionizing radiation.
|
J Am Chem Soc
|
2007
|
0.78
|
98
|
Quantitative detection of 8-Oxo-7,8-dihydro-2'-deoxyguanosine using chemical tagging and qPCR.
|
Chem Res Toxicol
|
2014
|
0.78
|
99
|
Rapid RNA strand scission following C2'-hydrogen atom abstraction.
|
J Am Chem Soc
|
2015
|
0.78
|
100
|
Transcription inhibition using modified pentanucleotides.
|
Bioorg Med Chem
|
2003
|
0.77
|
101
|
Irreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesion.
|
J Am Chem Soc
|
2014
|
0.77
|
102
|
A nucleic acid-directed, red light-induced chemical reaction.
|
Chem Commun (Camb)
|
2010
|
0.77
|
103
|
Photochemical control of DNA structure through radical disproportionation.
|
Chembiochem
|
2013
|
0.76
|
104
|
DNA interstrand cross-linking upon irradiation of aryl halide C-nucleotides.
|
J Org Chem
|
2014
|
0.76
|
105
|
DNA polymerase V kinetics support the instructive nature of an oxidized abasic lesion in Escherichia coli.
|
Biochemistry
|
2013
|
0.75
|
106
|
Human DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen.
|
ACS Chem Biol
|
2012
|
0.75
|
107
|
Interstrand cross-link and bioconjugate formation in RNA from a modified nucleotide.
|
J Org Chem
|
2014
|
0.75
|
108
|
Repair of the major lesion resulting from C5'-oxidation of DNA.
|
Biochemistry
|
2011
|
0.75
|