Published in Chem Res Toxicol on April 19, 2010
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Photochemical approach to probing different DNA structures. Angew Chem Int Ed Engl (2006) 0.89
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Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical. J Am Chem Soc (2007) 1.26
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A comprehensive comparison of DNA replication past 2-deoxyribose and its tetrahydrofuran analog in Escherichia coli. Nucleic Acids Res (2004) 1.22
Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues. J Am Chem Soc (2002) 1.20
Selective detection of 2-deoxyribonolactone in DNA. J Am Chem Soc (2005) 1.18
Effects of the C4'-oxidized abasic site on replication in Escherichia coli. An unusually large deletion is induced by a small lesion. Biochemistry (2004) 1.17
Synthesis and characterization of oligonucleotides containing the c4'-oxidized abasic site produced by bleomycin and other DNA damaging agents. Angew Chem Int Ed Engl (2003) 1.15
Transforming thymidine into a magnetic resonance imaging probe for monitoring gene expression. J Am Chem Soc (2013) 1.15
Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase. Proc Natl Acad Sci U S A (2008) 1.13
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Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes. Biochemistry (2003) 1.13
Scope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site. J Am Chem Soc (2009) 1.12
Preparation and analysis of oligonucleotides containing lesions resulting from C5'-oxidation. J Org Chem (2005) 1.12
Fapy.dG instructs Klenow exo(-) to misincorporate deoxyadenosine. J Am Chem Soc (2002) 1.11
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Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases. Biochemistry (2007) 1.08
Use of fluorescence sensors to determine that 2-deoxyribonolactone is the major alkali-labile deoxyribose lesion produced in oxidatively damaged DNA. Angew Chem Int Ed Engl (2007) 1.08
Studies on the replication of the ring opened formamidopyrimidine, Fapy.dG in Escherichia coli. Biochemistry (2007) 1.06
Photochemical generation and reactivity of the 5,6-dihydrouridin-6-yl radical. J Org Chem (2009) 1.06
DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesion. J Am Chem Soc (2009) 1.05
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DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. Biochemistry (2008) 1.03
Multinuclear NMR and kinetic analysis of DNA interstrand cross-link formation. J Am Chem Soc (2008) 1.03
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Action of human apurinic endonuclease (Ape1) on C1'-oxidized deoxyribose damage in DNA. DNA Repair (Amst) (2003) 1.00
Selective detection and quantification of oxidized abasic lesions in DNA. J Am Chem Soc (2007) 0.99
Product and mechanistic analysis of the reactivity of a C6-pyrimidine radical in RNA. J Am Chem Soc (2011) 0.99
Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles. J Am Chem Soc (2012) 0.99
Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone. J Am Chem Soc (2012) 0.98
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Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae. Nucleic Acids Res (2005) 0.97
Probing the configurations of formamidopyrimidine lesions Fapy.dA and Fapy.dG in DNA using endonuclease IV. Biochemistry (2004) 0.97
Facile quantification of lesions derived from 2'-deoxyguanosine in DNA. J Am Chem Soc (2007) 0.97
Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. Biochemistry (2010) 0.97
Independent generation and characterization of a C2'-oxidized abasic site in chemically synthesized oligonucleotides. J Org Chem (2004) 0.96
Replication of an oxidized abasic site in Escherichia coli by a dNTP-stabilized misalignment mechanism that reads upstream and downstream nucleotides. Biochemistry (2006) 0.96
DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2). J Am Chem Soc (2007) 0.96
Evidence for glycosidic bond rotation in a nucleobase peroxyl radical and its effect on tandem lesion formation. J Org Chem (2004) 0.95
Direct strand scission in double stranded RNA via a C5-pyrimidine radical. J Am Chem Soc (2012) 0.94
Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion. J Am Chem Soc (2010) 0.94
Synthesis of oligonucleotides containing Fapy.dG (N(6)-(2-deoxy-alpha,beta-D-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine) using a 5'-dimethoxytrityl dinucleotide phosphoramidite. J Org Chem (2005) 0.94
Mild generation of 5-(2'-deoxyuridinyl)methyl radical from a phenyl selenide precursor. Org Lett (2004) 0.94
Direct strand scission from a nucleobase radical in RNA. J Am Chem Soc (2010) 0.94
Inhibition of short patch and long patch base excision repair by an oxidized abasic site. Biochemistry (2010) 0.93
Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine. Org Lett (2012) 0.93
Fapy.dA induces nucleotide misincorporation translesionally by a DNA polymerase. Angew Chem Int Ed Engl (2002) 0.92
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Synthesis of oligonucleotides and thermal stability of duplexes containing the beta-C-nucleoside analogue of Fapy*dG. Chem Res Toxicol (2002) 0.92
Nucleosome core particle-catalyzed strand scission at abasic sites. Biochemistry (2013) 0.91
Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates. J Am Chem Soc (2006) 0.90
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Long patch base excision repair compensates for DNA polymerase β inactivation by the C4'-oxidized abasic site. Biochemistry (2010) 0.90
Histone modification via rapid cleavage of C4'-oxidized abasic sites in nucleosome core particles. J Am Chem Soc (2013) 0.89
Interaction of DNA containing Fapy.dA or its C-nucleoside analogues with base excision repair enzymes. Implications for mutagenesis and enzyme inhibition. Biochemistry (2002) 0.89
Synthesis of 5,12-dioxocyclam nickel (II) complexes having quinoxaline substituents at the 6 and 13 positions as potential DNA bis-intercalating and cleaving agents. J Org Chem (2003) 0.88
Protein binding has a large effect on radical mediated DNA damage. J Am Chem Soc (2008) 0.88
DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases. Bioorg Med Chem (2012) 0.87
Photochemical control of RNA structure by disrupting π-stacking. J Am Chem Soc (2012) 0.86
Independent generation and study of 5,6-Dihydro-2'-deoxyuridin-6-yl, a member of the major family of reactive intermediates formed in DNA from the effects of gamma-radiolysis. J Org Chem (2003) 0.86
Excision of formamidopyrimidine lesions by endonucleases III and VIII is not a major DNA repair pathway in Escherichia coli. Nucleic Acids Res (2005) 0.86
Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides. Bioorg Med Chem (2011) 0.86
Hydrogen bonding contributes to the selectivity of nucleotide incorporation opposite an oxidized abasic lesion. J Am Chem Soc (2008) 0.85
Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine. Chembiochem (2011) 0.85
The mutagenicity of thymidine glycol in Escherichia coli is increased when it is part of a tandem lesion. Biochemistry (2009) 0.84
Synthesis of cross-linked DNA containing oxidized abasic site analogues. J Org Chem (2014) 0.83
DNA double strand cleavage via interstrand hydrogen atom abstraction. J Am Chem Soc (2013) 0.83
Gamma-radiolysis and hydroxyl radical produce interstrand cross-links in DNA involving thymidine. Chem Res Toxicol (2007) 0.83
5,6-Dihydropyrimidine peroxyl radical reactivity in DNA. J Am Chem Soc (2014) 0.83
DNA polymerase λ inactivation by oxidized abasic sites. Biochemistry (2013) 0.82
Synthesis and analysis of oligonucleotides containing abasic site analogues. J Org Chem (2008) 0.82
Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA. Chem Res Toxicol (2010) 0.82
Mechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates. Nucleic Acids Res (2005) 0.82
Deconvoluting the reactivity of two intermediates formed from modified pyrimidines. Org Lett (2013) 0.81
Probing interactions between lysine residues in histone tails and nucleosomal DNA via product and kinetic analysis. ACS Chem Biol (2014) 0.81
The effect of the 2-amino group of 7,8-dihydro-8-oxo-2'-deoxyguanosine on translesion synthesis and duplex stability. Nucleic Acids Res (2005) 0.81
Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase. J Am Chem Soc (2009) 0.81
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Quantification of 8-oxodGuo lesions in double-stranded DNA using a photoelectrochemical DNA sensor. Anal Chem (2012) 0.80
DNA damage and interstrand cross-link formation upon irradiation of aryl iodide C-nucleotide analogues. J Org Chem (2010) 0.80
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DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. Bioorg Med Chem (2008) 0.79
DNA damage by histone radicals in nucleosome core particles. J Am Chem Soc (2014) 0.79
Preparation and analysis of oligonucleotides containing the c4'-oxidized abasic site and related mechanistic probes. J Org Chem (2005) 0.79
Quantitative detection of 8-Oxo-7,8-dihydro-2'-deoxyguanosine using chemical tagging and qPCR. Chem Res Toxicol (2014) 0.78
Rapid RNA strand scission following C2'-hydrogen atom abstraction. J Am Chem Soc (2015) 0.78
Nucleotide excision repair of chemically stabilized analogues of DNA interstrand cross-links produced from oxidized abasic sites. Biochemistry (2014) 0.78