Published in Trends Genet on February 01, 1991
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2. Mol Cell Biol (1996) 2.79
The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins. EMBO J (1991) 2.30
DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism. EMBO J (1992) 2.15
Identification of nucleotide preferences in DNA sequences recognised specifically by c-Ets-1 protein. Nucleic Acids Res (1992) 1.82
Characterization of the transcription activation function and the DNA binding domain of transcriptional enhancer factor-1. EMBO J (1993) 1.68
Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression. Mol Cell Biol (1992) 1.61
p21ras mediates control of IL-2 gene promoter function in T cell activation. EMBO J (1992) 1.56
The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Mol Cell Biol (2001) 1.48
Nuclear factor I and epithelial cell-specific transcription of human papillomavirus type 16. J Virol (1993) 1.31
Opposite orientations of DNA bending by c-Myc and Max. Proc Natl Acad Sci U S A (1992) 1.27
Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals. J Cell Biol (1995) 1.11
Participation of Ets transcription factors in the glucocorticoid response of the rat tyrosine aminotransferase gene. Mol Cell Biol (1994) 1.11
Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter. Mol Cell Biol (1991) 1.07
Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain. Mol Cell Biol (1995) 1.04
Cell cycle regulation of the c-Myc transcriptional activation domain. Mol Cell Biol (1993) 1.01
Identification of the functional components of the Ras signaling pathway regulating pituitary cell-specific gene expression. Mol Cell Biol (1994) 1.01
Functional interference between the Spi-1/PU.1 oncoprotein and steroid hormone or vitamin receptors. EMBO J (1993) 0.98
AP-1 factors play an important role in transformation induced by the v-rel oncogene. Mol Cell Biol (1998) 0.97
Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity. Proc Natl Acad Sci U S A (1994) 0.97
Dimerization of the testis brain RNA-binding protein (translin) is mediated through its C-terminus and is required for DNA- and RNA-binding. Nucleic Acids Res (1998) 0.96
Transcriptional downregulation of the retina-specific QR1 gene by pp60v-src and identification of a novel v-src-responsive unit. Mol Cell Biol (1993) 0.93
Characterization of an enhancer upstream from the muscle-type promoter of a gene encoding 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Nucleic Acids Res (1992) 0.92
Suppression of albumin enhancer activity by H-ras and AP-1 in hepatocyte cell lines. Mol Cell Biol (1994) 0.91
ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors. J Virol (1996) 0.91
The neurotensin gene is a downstream target for Ras activation. J Clin Invest (1995) 0.91
Enhancer-mediated role for polyomavirus middle T/small T in DNA replication. J Virol (1995) 0.91
Activation of codependent transcription factors is required for transcriptional induction of the vgf gene by nerve growth factor and Ras. Mol Cell Biol (1996) 0.90
Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: a new human member of the ets oncogene family. Nucleic Acids Res (1993) 0.89
Transcriptional activation of the CEF-4/9E3 cytokine gene by pp60v-src. Mol Cell Biol (1992) 0.89
Transcription factor binding and spacing constraints in the human beta-actin proximal promoter. Nucleic Acids Res (1991) 0.88
Transcription inhibition of the somatic-type phosphoglycerate kinase 1 gene in vitro by a testis-specific factor that recognizes a sequence similar to the binding site for Ets oncoproteins. Nucleic Acids Res (1991) 0.86
XrpFI, an amphibian transcription factor composed of multiple polypeptides immunologically related to the GA-binding protein alpha and beta subunits, is differentially expressed during Xenopus laevis development. Mol Cell Biol (1993) 0.86
Role of distinct mitogen-activated protein kinase pathways and cooperation between Ets-2, ATF-2, and Jun family members in human urokinase-type plasminogen activator gene induction by interleukin-1 and tetradecanoyl phorbol acetate. Mol Cell Biol (1999) 0.86
Identification of positive and negative regulatory elements involved in the retinoic acid/cAMP induction of Fgf-3 transcription in F9 cells. Nucleic Acids Res (1993) 0.85
Threonine affects intestinal function, protein synthesis and gene expression of TOR in Jian carp (Cyprinus carpio var. Jian). PLoS One (2013) 0.84
Ras mediates Src but not epidermal growth factor-receptor tyrosine kinase signaling pathways in GH4 neuroendocrine cells. Proc Natl Acad Sci U S A (1994) 0.83
Negative regulatory elements upstream of a novel exon of the neuronal nicotinic acetylcholine receptor alpha 2 subunit gene. Nucleic Acids Res (1993) 0.82
Modified binding of proteins from calcitonin-negative tumor cells to the neuroendocrine-specific CANNTG motif of the calcitonin gene. Nucleic Acids Res (1993) 0.79
The mouse proline-rich protein MP6 promoter binds isoprenaline-inducible parotid nuclear proteins via a highly conserved NFkB/rel-like site. Nucleic Acids Res (1991) 0.75
Promoter sequences of eukaryotic protein-coding genes. Science (1980) 19.96
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence. Proc Natl Acad Sci U S A (1980) 10.27
Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes. Nature (1980) 10.22
The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements. Cell (1983) 5.67
The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites. EMBO J (1990) 2.73
The immunoglobulin heavy-chain B-lymphocyte enhancer efficiently stimulates transcription in non-lymphoid cells. EMBO J (1986) 2.56
A Harvey-ras responsive transcription element is also responsive to a tumour-promoter and to serum. Nature (1988) 2.48
Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer. Proc Natl Acad Sci U S A (1984) 2.44
Short and long range activation by the SV40 enhancer. Nucleic Acids Res (1984) 2.35
A T to A base substitution and small deletions in the conalbumin TATA box drastically decrease specific in vitro transcription. Nucleic Acids Res (1981) 2.31
The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins. EMBO J (1991) 2.30
The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer. Cell (1987) 2.24
Transforming but not immortalizing oncogenes activate the transcription factor PEA1. EMBO J (1988) 2.14
Net, a new ets transcription factor that is activated by Ras. Genes Dev (1994) 2.12
Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter. Genes Dev (1996) 1.98
PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes. EMBO J (1989) 1.97
A novel modulator domain of Ets transcription factors. Genes Dev (1992) 1.97
Transformation suppressor activity of a Jun transcription factor lacking its activation domain. Nature (1991) 1.92
Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation. EMBO J (1999) 1.76
Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer. Mol Cell Biol (1987) 1.71
Expression of raf oncogenes activates the PEA1 transcription factor motif. Mol Cell Biol (1989) 1.66
Prediction of future metastasis and molecular characterization of head and neck squamous-cell carcinoma based on transcriptome and genome analysis by microarrays. Oncogene (2008) 1.63
The contribution of the acidic domain of MDM2 to p53 and MDM2 stability. Oncogene (2001) 1.57
Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display. Oncogene (2006) 1.56
Point mutation in the TATA box curtails expression of sea urchin H2A histone gene in vivo. Nature (1981) 1.51
Effect of histone acetylation on structure and in vitro transcription of chromatin. Nucleic Acids Res (1978) 1.43
Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2. Oncogene (1997) 1.41
Preferential in vitro assembly of nucleosome cores on some AT-rich regions of SV40 DNA. Nucleic Acids Res (1979) 1.41
The immunoglobulin heavy chain enhancer is stimulated by the adenovirus type 2 E1A products in mouse fibroblasts. Proc Natl Acad Sci U S A (1986) 1.39
ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines. Br J Cancer (2010) 1.38
Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J (1996) 1.34
Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2. Genes Dev (2001) 1.30
Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins. Proc Natl Acad Sci U S A (1993) 1.29
Mutational analysis of the contribution of sequence motifs within the IgH enhancer to tissue specific transcriptional activation. Nucleic Acids Res (1988) 1.26
Two independent activation domains in c-Ets-1 and c-Ets-2 located in non-conserved sequences of the ets gene family. Oncogene (1992) 1.25
Differential expression profiling of head and neck squamous cell carcinoma (HNSCC). Br J Cancer (2003) 1.23
Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. EMBO J (1996) 1.22
Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J (2001) 1.20
Reversion of Ras transformed cells by Ets transdominant mutants. Oncogene (1994) 1.14
Transcription by eukaryotic RNA polymerases A and B of chromatin assembled in vitro. Eur J Biochem (1979) 1.12
p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53. Oncogene (1999) 1.12
Transcription of in vitro assembled chromatin by Escherichia coli RNA polymerase. J Mol Biol (1979) 1.12
v-jun is a transcriptional activator, but not in all cell-lines. Nucleic Acids Res (1988) 1.12
The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter. J Biol Chem (1997) 1.11
The contribution of the RING finger domain of MDM2 to cell cycle progression. Oncogene (2000) 1.09
MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest. Oncogene (1995) 1.08
Transcription abnormalities potentiate apoptosis of normal human fibroblasts. Mol Med (1997) 1.08
Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter. Mol Cell Biol (1991) 1.07
The net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock. Mol Cell Biol (1999) 1.06
MDM2 expression during mouse embryogenesis and the requirement of p53. Mech Dev (1998) 1.04
Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain. Mol Cell Biol (1995) 1.04
Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev (2001) 1.04
B-lymphocyte targeting of gene expression in transgenic mice with the immunoglobulin heavy-chain enhancer. Nucleic Acids Res (1986) 1.01
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice. Oncogene (1999) 1.01
Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression. Mol Cell Biol (1997) 1.01
Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells. EMBO J (2000) 1.01
MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis. EMBO J (2000) 1.01
Oncogene v-jun modulates DNA replication. Oncogene (1990) 1.01
The ternary complex factor Net contains two distinct elements that mediate different responses to MAP kinase signalling cascades. Oncogene (2000) 0.99
Studies on the mechanism of transcription of nucleosomal complexes. Eur J Biochem (1980) 0.99
AP1, a composite transcription factor implicated in abnormal growth control. Prog Growth Factor Res (1989) 0.98
The MLV and SV40 enhancers have a similar pattern of transcriptional activation. Nucleic Acids Res (1984) 0.95
The ternary complex factor Net/Elk-3 participates in the transcriptional response to hypoxia and regulates HIF-1 alpha. Oncogene (2007) 0.93
Potentiator effect of the SV40 72-bp repeat on initiation of transcription from heterologous promoter elements. Cold Spring Harb Symp Quant Biol (1983) 0.92
Oncogenic conversion of Ets affects redox regulation in-vivo and in-vitro. Nucleic Acids Res (1993) 0.91
Serum, AP-1 and Ets-1 stimulate the human ets-1 promoter. Nucleic Acids Res (1992) 0.90
The oncoprotein v-Ets is less selective in DNA binding than c-Ets-1 due to the C-terminal sequence change. Oncogene (1994) 0.89
Targetting of the N-terminal domain of the human papillomavirus type 16 E6 oncoprotein with monomeric ScFvs blocks the E6-mediated degradation of cellular p53. J Mol Recognit (2000) 0.89
Modulation of ETS-1 transcriptional activity by huUBC9, a ubiquitin-conjugating enzyme. Oncogene (1997) 0.86
Association between polymorphism in p21(Waf1/Cip1) cyclin-dependent kinase inhibitor gene and human oral cancer. Clin Cancer Res (2000) 0.86
Locations of the ets subfamily members net, elk1, and sap1 (ELK3, ELK1, and ELK4) on three homologous regions of the mouse and human genomes. Genomics (1995) 0.86
Net-b, a Ras-insensitive factor that forms ternary complexes with serum response factor on the serum response element of the fos promoter. Mol Cell Biol (1997) 0.85
Oncogenic conversion alters the transcriptional properties of ets. Cell Growth Differ (1992) 0.84
Loss of MDM2 expression in human head and neck squamous cell carcinomas and clinical significance. Oral Oncol (2001) 0.83
Tumorigenic and metastatic properties of two ras-oncogene transfected rat fibrosarcoma cell lines defective in c-jun. Oncogene (1994) 0.83
The apoptotic and transcriptional transactivation activities of p53 can be dissociated. Biochem Cell Biol (1997) 0.82
Circulating p53 antibodies as early markers of oral cancer: correlation with p53 alterations. Clin Cancer Res (1998) 0.81
Loss of HOP tumour suppressor expression in head and neck squamous cell carcinoma. Br J Cancer (2004) 0.80
Defect in the p53-Mdm2 autoregulatory loop resulting from inactivation of TAF(II)250 in cell cycle mutant tsBN462 cells. Mol Cell Biol (2000) 0.80
Cyclin L1 (CCNL1) gene alterations in human head and neck squamous cell carcinoma. Br J Cancer (2006) 0.80
Cloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscle. Biochem J (1998) 0.80
Correlation between p53 gene mutations and circulating antibodies in betel- and tobacco-consuming North Indian population. Oral Oncol (2001) 0.79
The activation of RNA polymerase by alkylammonium ions. Nucleic Acids Res (1975) 0.79
Repression by Jun of the Polyoma-virus enhancer overrides activation in a cell specific manner. Nucleic Acids Res (1991) 0.78
Tumour regression in a ligand inducible manner mediated by a chimeric tumour suppressor derived from p53. Oncogene (2000) 0.78
Ets transcription factor binding site is required for positive and TNF alpha-induced negative promoter regulation. Nucleic Acids Res (1993) 0.78
Chemical modification of ribonucleic acid polymerase with N-bromosuccinimide. Biochem Soc Trans (1975) 0.77
A novel eukaryotic promoter element: the simian virus 40 72 base pair repeat. Fed Proc (1984) 0.77
The isolation, mapping and transcription in vitro of a beta 0-thalassaemia globin gene. Eur J Biochem (1981) 0.76
The conalbumin "TATA" box sequence and the SV40 72 base-pair repeat region influence expression of a chimeric gene in vivo. Prog Clin Biol Res (1982) 0.75