Published in Nucleic Acids Res on April 24, 1981
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc Natl Acad Sci U S A (1982) 6.57
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol Cell Biol (1988) 5.60
The yeast his3 promoter contains at least two distinct elements. Proc Natl Acad Sci U S A (1982) 3.40
Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene. Proc Natl Acad Sci U S A (1982) 2.90
Promotion of specific in vitro transcription by excised "TATA" box sequences inserted in a foreign nucleotide environment. Nucleic Acids Res (1981) 2.57
Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J Virol (1994) 2.41
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Res (1984) 2.31
Determination of the promoter region of mouse ribosomal RNA gene by an in vitro transcription system. Proc Natl Acad Sci U S A (1984) 2.18
In vitro transcription of a cloned mouse ribosomal RNA gene. Nucleic Acids Res (1981) 2.01
Simian virus 40 major late promoter: an upstream DNA sequence required for efficient in vitro transcription. Mol Cell Biol (1984) 1.94
ATA box transcription mutation in beta-thalassemia. Nucleic Acids Res (1983) 1.59
Novel chicken actin gene: third cytoplasmic isoform. Mol Cell Biol (1985) 1.57
Specific in vitro initiation of transcription on the adenovirus type 2 early and late EII transcription units. Proc Natl Acad Sci U S A (1981) 1.52
Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors. Mol Cell Biol (1989) 1.50
DNA sequences required for specific and efficient initiation of transcription at the polyoma virus early promoter. Mol Cell Biol (1982) 1.34
Cell-specificity of the chicken ovalbumin and conalbumin promoters. EMBO J (1987) 1.22
A heteromeric transcription factor required for mammalian RNA polymerase II. Nucleic Acids Res (1990) 1.02
Organisation of feather keratin genes in the chick genome. Nucleic Acids Res (1982) 0.91
Complex requirements for RNA polymerase III transcription of the Xenopus U6 promoter. Nucleic Acids Res (1990) 0.90
Effects of the adenovirus 2 late promoter on simian virus 40 transcription and replication. J Virol (1986) 0.89
In vitro accurate initiation of transcription on the adenovirus type 2 IVa2 gene which does not contain a TATA box. Nucleic Acids Res (1982) 0.88
Introduction of restriction enzyme sites in protein-coding DNA sequences by site-specific mutagenesis not affecting the amino acid sequence: a computer program. Nucleic Acids Res (1984) 0.84
Delineation of DNA sequences that are important for in vitro transcription from the adenovirus EIIa late promoter. Mol Cell Biol (1988) 0.75
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Regulatory sequences involved in the promotion and termination of RNA transcription. Annu Rev Genet (1979) 54.83
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Promoter sequences of eukaryotic protein-coding genes. Science (1980) 19.96
E. coli RNA polymerase interacts homologously with two different promoters. Cell (1980) 19.71
Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo. Proc Natl Acad Sci U S A (1980) 16.88
Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter. Proc Natl Acad Sci U S A (1975) 14.75
pBR322 restriction map derived from the DNA sequence: accurate DNA size markers up to 4361 nucleotide pairs long. Nucleic Acids Res (1978) 13.22
Coding potential and regulatory signals of the polyoma virus genome. Nature (1980) 11.24
Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes. Nature (1980) 10.22
Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proc Natl Acad Sci U S A (1980) 10.22
Genetic regulation: the Lac control region. Science (1975) 9.48
Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome. Proc Natl Acad Sci U S A (1978) 8.36
Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system. Cell (1980) 8.02
Nucleotide sequence of an RNA polymerase binding site from the DNA of bacteriophage fd. Proc Natl Acad Sci U S A (1975) 7.14
Messenger RNA for the Ad2 DNA binding protein: DNA sequences encoding the first leader and heterogenity at the mRNA 5' end. Cell (1979) 5.28
Organization and sequence studies of the 17-piece chicken conalbumin gene. Nature (1979) 4.36
Ubiquitous and gene-specific regulatory 5' sequences in a sea urchin histone DNA clone coding for histone protein variants. Nucleic Acids Res (1980) 3.80
Leader sequences of Strongylocentrotus purpuratus histone mRNAs start at a unique heptanucleotide common to all five histone genes. Proc Natl Acad Sci U S A (1980) 2.54
Transcriptional fidelity of histone genes injected into Xenopus oocyte nuclei. Nature (1980) 1.81
The effect of bisulfite modification on the template activity of DNA for DNA polymerase I. Nucleic Acids Res (1974) 1.46
Contacts between Escherichia coli RNA polymerase and thymines in the lac UV5 promoter. Proc Natl Acad Sci U S A (1979) 1.31
Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem (1981) 49.46
In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00
The nuclear receptor superfamily: the second decade. Cell (1995) 24.99
Isolation of high-molecular-weight DNA from mammalian cells. Eur J Biochem (1973) 24.38
Promoter sequences of eukaryotic protein-coding genes. Science (1980) 19.96
The ovalbumin gene-sequence of putative control regions. Nucleic Acids Res (1980) 18.04
A reliable method for the recovery of DNA fragments from agarose and acrylamide gels. Anal Biochem (1981) 15.38
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries. Proc Natl Acad Sci U S A (1978) 14.82
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 11.35
Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence. Proc Natl Acad Sci U S A (1980) 10.27
Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes. Nature (1980) 10.22
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science (1993) 9.94
Folding of the DNA double helix in chromatin-like structures from simian virus 40. Proc Natl Acad Sci U S A (1975) 9.70
Organisation and sequences at the 5' end of a cloned complete ovalbumin gene. Nature (1979) 9.30
A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature (1988) 9.07
Electron microscopic and biochemical evidence that chromatin structure is a repeating unit. Cell (1975) 8.90
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem Biophys Res Commun (1997) 7.87
Deletions covering the putative promoter region of early mRNAs of simian virus 40 do not abolish T-antigen expression. Proc Natl Acad Sci U S A (1980) 7.77
Multiple sequence motifs are involved in SV40 enhancer function. EMBO J (1986) 7.76
Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences. Nature (1983) 7.22
Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature (1985) 7.14
Ovalbumin gene is split in chicken DNA. Nature (1977) 7.05
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell (1988) 6.59
Functional domains of the human estrogen receptor. Cell (1987) 6.52
Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci U S A (1996) 6.48
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (1995) 6.37
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res (1999) 6.35
The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell (1989) 6.24
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol Cell (2000) 6.14
Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J (1986) 6.08
Nuclear receptors enhance our understanding of transcription regulation. Trends Genet (1988) 5.95
The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements. Cell (1983) 5.67
Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science (1996) 5.55
Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature (1987) 5.47
The SV40 early region TATA box is required for accurate in vitro initiation of transcription. Nature (1981) 5.43
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature (1995) 5.40
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet (1999) 5.31
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci U S A (1997) 5.24
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res (1982) 5.14
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature (1991) 5.13
Identification of a second human retinoic acid receptor. Nature (1988) 5.11
Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J (1990) 5.05
Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development (2000) 5.03
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (1985) 5.00
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J (1996) 4.96
The repeated GC-rich motifs upstream from the TATA box are important elements of the SV40 early promoter. Nucleic Acids Res (1983) 4.93
DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes. Nucleic Acids Res (1979) 4.81
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature (1995) 4.79
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter. Nature (1986) 4.77
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J (1995) 4.72
A canonical structure for the ligand-binding domain of nuclear receptors. Nat Struct Biol (1996) 4.69
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J (1996) 4.65
Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell (1995) 4.64
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J (1986) 4.47
Organization and sequence studies of the 17-piece chicken conalbumin gene. Nature (1979) 4.36
Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. Proc Natl Acad Sci U S A (1982) 4.30
Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor. EMBO J (1984) 4.28
The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator. Cell (1988) 4.22
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell (1988) 4.17
Alpha-amanitin: a specific inhibitor of one of two DNA-pendent RNA polymerase activities from calf thymus. Biochem Biophys Res Commun (1970) 4.16
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem (2000) 4.15
The ovalbumin gene family: structure of the X gene and evolution of duplicated split genes. Cell (1980) 4.14
Cooperativity and hierarchical levels of functional organization in the SV40 enhancer. Cell (1988) 4.03
A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro. Nature (1985) 4.01
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci U S A (1995) 3.94
Distinct classes of transcriptional activating domains function by different mechanisms. Cell (1990) 3.75
A third human retinoic acid receptor, hRAR-gamma. Proc Natl Acad Sci U S A (1989) 3.74
Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin. Nature (1989) 3.72
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1. Cell (1991) 3.71
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol Cell (2001) 3.70
Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements. Nature (1984) 3.68
The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways. EMBO J (1998) 3.64
Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem Sci (1992) 3.63
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J (1990) 3.59
Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development (1994) 3.53
Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell (1991) 3.53
Steroid hormone receptors compete for factors that mediate their enhancer function. Cell (1989) 3.50
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell (1994) 3.46
The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence. Cell (1988) 3.41
Isolation by molecular cloning of a fragment in the split ovalbumin gene. Nature (1978) 3.40
The human oestrogen receptor functions in yeast. Nature (1988) 3.32
Molecular cloning of extensive sequences of the in vitro synthesized chicken ovalbumin structural gene. Nucleic Acids Res (1977) 3.32
Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts. Nature (1986) 3.25
Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci U S A (1984) 3.25
The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties. EMBO J (1989) 3.23
Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell (1994) 3.16
An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite. Nucleic Acids Res (1983) 3.11
Structure of transcribing chromatin. Prog Nucleic Acid Res Mol Biol (1980) 3.09
Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development (1994) 2.98
Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc Natl Acad Sci U S A (1993) 2.96