PubRank

Joachim Herz

Author PubWeight™ 168.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005 13.00
2 Suppression of aging in mice by the hormone Klotho. Science 2005 8.11
3 LRP: role in vascular wall integrity and protection from atherosclerosis. Science 2003 3.89
4 Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends Mol Med 2004 3.44
5 Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron 2005 3.25
6 Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure. Proc Natl Acad Sci U S A 2002 3.03
7 Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. J Biol Chem 2010 2.72
8 Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. J Biol Chem 2002 2.67
9 Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 2007 2.55
10 TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem 2009 2.40
11 Reelin activates SRC family tyrosine kinases in neurons. Curr Biol 2003 2.29
12 Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Med 2012 2.01
13 Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. J Biol Chem 2011 1.88
14 Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. J Biol Chem 2002 1.88
15 Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain. J Biol Chem 2002 1.83
16 Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Mol Cell Biol 2004 1.81
17 Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2. J Clin Invest 2010 1.77
18 Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae. J Biol Chem 2002 1.74
19 Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J Clin Invest 2007 1.73
20 Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. PLoS One 2009 1.67
21 Receptor clustering is involved in Reelin signaling. Mol Cell Biol 2004 1.66
22 Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J 2006 1.66
23 Reelin modulates NMDA receptor activity in cortical neurons. J Neurosci 2005 1.65
24 TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor. Mol Cell Biol 2010 1.64
25 Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. J Biol Chem 2003 1.63
26 Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One 2008 1.60
27 Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis. Arterioscler Thromb Vasc Biol 2008 1.58
28 ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling. Proc Natl Acad Sci U S A 2010 1.57
29 Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. J Biol Chem 2003 1.56
30 Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum Mol Genet 2005 1.56
31 Interaction of reelin signaling and Lis1 in brain development. Nat Genet 2003 1.56
32 Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J 2006 1.51
33 Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase. J Biol Chem 2003 1.48
34 Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes. Structure 2003 1.48
35 Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo. J Bone Miner Res 2013 1.47
36 Apolipoprotein E induces antiinflammatory phenotype in macrophages. Arterioscler Thromb Vasc Biol 2011 1.47
37 Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure. J Biol Chem 2002 1.47
38 Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. J Biol Chem 2009 1.45
39 Reelin signaling directly affects radial glia morphology and biochemical maturation. Development 2003 1.44
40 LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome. PLoS One 2007 1.44
41 Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration. J Biol Chem 2012 1.43
42 The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. J Neurosci 2004 1.42
43 Gamma-secretase limits the inflammatory response through the processing of LRP1. Sci Signal 2008 1.38
44 LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. Am J Hum Genet 2010 1.37
45 LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. J Biol Chem 2008 1.36
46 TDP-43 aggregation in neurodegeneration: are stress granules the key? Brain Res 2012 1.35
47 Reelin signaling antagonizes beta-amyloid at the synapse. Proc Natl Acad Sci U S A 2009 1.32
48 Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. J Biol Chem 2004 1.31
49 Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity. J Neurosci 2006 1.26
50 The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits. J Biol Chem 2005 1.25
51 Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. J Clin Invest 2007 1.22
52 Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta). J Biol Chem 2005 1.21
53 Essential role of the apolipoprotein E receptor-2 in sperm development. J Biol Chem 2003 1.19
54 Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. PLoS Negl Trop Dis 2011 1.17
55 Emerging topics in Reelin function. Eur J Neurosci 2010 1.17
56 Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1. Neuron 2012 1.14
57 Functions of lipoprotein receptors in neurons. J Lipid Res 2003 1.11
58 Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. PLoS Biol 2011 1.11
59 Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in autosomal recessive mulefoot disease. Genomics 2006 1.10
60 Genetic modulation of tau phosphorylation in the mouse. J Neurosci 2003 1.09
61 LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation. PLoS One 2009 1.09
62 ApoE receptor 2 controls neuronal survival in the adult brain. Curr Biol 2006 1.08
63 Mutations in VLDLR as a cause for autosomal recessive cerebellar ataxia with mental retardation (dysequilibrium syndrome). J Child Neurol 2009 1.08
64 Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem 2003 1.08
65 Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. Neuron 2013 1.07
66 Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family. Biol Chem 2010 1.07
67 Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice. J Comp Neurol 2003 1.06
68 Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Mol Cell Biol 2004 1.05
69 "Devolution" of bipedality. Proc Natl Acad Sci U S A 2008 1.05
70 Signaling through LRP1: Protection from atherosclerosis and beyond. Biochem Pharmacol 2010 1.03
71 Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation. Arterioscler Thromb Vasc Biol 2009 1.03
72 Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation. J Neurosci 2010 1.02
73 Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells. J Neurosci 2013 1.01
74 Reelin induces EphB activation. Cell Res 2013 1.01
75 Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. J Neurosci 2004 1.00
76 An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. J Clin Invest 2014 0.99
77 Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Glia 2010 0.98
78 Dentate granule cells in reeler mutants and VLDLR and ApoER2 knockout mice. Exp Neurol 2002 0.97
79 The Pafah1b complex interacts with the reelin receptor VLDLR. PLoS One 2007 0.96
80 The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. PLoS One 2008 0.95
81 Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency. Blood 2003 0.93
82 Standardizing scavenger receptor nomenclature. J Immunol 2014 0.93
83 Cancer. A bull's eye for targeted lung cancer therapy. Science 2004 0.93
84 Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome. PLoS One 2010 0.93
85 The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells. Nat Commun 2012 0.92
86 LDL receptor-related proteins in neurodevelopment. Traffic 2003 0.92
87 LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. PLoS One 2009 0.92
88 LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins. Proc Natl Acad Sci U S A 2014 0.91
89 Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein. J Biol Chem 2003 0.90
90 Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo. PLoS One 2010 0.90
91 Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol. Blood 2004 0.90
92 The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain. J Neurosci 2013 0.90
93 Phosphoinositide binding by the disabled-1 PTB domain is necessary for membrane localization and Reelin signal transduction. J Biol Chem 2005 0.90
94 APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife 2013 0.90
95 Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1. J Cell Biochem 2006 0.87
96 ApoER2 function in the establishment and maintenance of retinal synaptic connectivity. J Neurosci 2011 0.87
97 Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes. J Biol Chem 2013 0.85
98 Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor. J Biol Chem 2011 0.85
99 Differential functions of the Apoer2 intracellular domain in selenium uptake and cell signaling. Biol Chem 2009 0.85
100 TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration. Biol Chem 2012 0.85
101 A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition. Proc Natl Acad Sci U S A 2009 0.84
102 Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates. Nat Commun 2012 0.84
103 Integration of endocytosis and signal transduction by lipoprotein receptors. Sci STKE 2003 0.84
104 Lrp4: A novel modulator of extracellular signaling in craniofacial organogenesis. Am J Med Genet A 2010 0.84
105 Identification of alternatively spliced Dab1 and Fyn isoforms in pig. BMC Neurosci 2011 0.83
106 Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Dev Biol 2005 0.83
107 Contribution of the Reelin signaling pathways to nociceptive processing. Eur J Neurosci 2008 0.83
108 Extracting β-amyloid from Alzheimer's disease. Proc Natl Acad Sci U S A 2012 0.82
109 Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia 2013 0.81
110 Wnt signaling in the murine diastema. Eur J Orthod 2011 0.80
111 Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). J Biol Chem 2013 0.80
112 Mouse models as tools for dissecting disorders of lipoprotein metabolism. Semin Cell Dev Biol 2003 0.80
113 The apoE receptor apoER2 is involved in the maintenance of efficient synaptic plasticity. Neurobiol Aging 2005 0.80
114 Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice. J Comp Neurol 2002 0.79
115 News on the molecular regulation and function of hepatic low-density lipoprotein receptor and LDLR-related protein 1. Curr Opin Lipidol 2017 0.75
116 Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo. Curr Alzheimer Res 2014 0.75