Published in JAMA on November 14, 2012
Vitamin D-binding protein and vitamin D status of black Americans and white Americans. N Engl J Med (2013) 9.87
Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ (2014) 5.88
Racial differences in the association of serum 25-hydroxyvitamin D concentration with coronary heart disease events. JAMA (2013) 2.98
Genetically low vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts. BMJ (2014) 1.83
Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis. Am J Nephrol (2015) 1.46
Genetic Variations in the Vitamin D Receptor Predict Type 2 Diabetes and Myocardial Infarction in a Community-Based Population: The Tromsø Study. PLoS One (2015) 1.39
Vitamin D and inflammatory diseases. J Inflamm Res (2014) 1.07
Genetic variants modifying the influence of vitamin D. JAMA (2013) 1.06
Vitamin D Binding Protein Impact on 25-Hydroxyvitamin D Levels under Different Physiologic and Pathologic Conditions. Int J Endocrinol (2014) 1.05
Association of 25-hydroxyvitamin D and parathyroid hormone with incident hypertension: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol (2014) 1.01
Vitamin D deficiency--prognostic marker or mortality risk factor in end stage renal disease patients with diabetes mellitus treated with hemodialysis--a prospective multicenter study. PLoS One (2015) 0.97
Links between Vitamin D Deficiency and Cardiovascular Diseases. Biomed Res Int (2015) 0.96
Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial. J Clin Endocrinol Metab (2014) 0.95
Genetic risk factors for hypertrophic scar development. J Burn Care Res (2013) 0.94
Optimal Vitamin D Supplementation Doses that Minimize the Risk for Both Low and High Serum 25-Hydroxyvitamin D Concentrations in the General Population. Nutrients (2015) 0.92
Vitamin d and its relationship with obesity and muscle. Int J Endocrinol (2014) 0.92
An integrated approach to defining genetic and environmental determinants for major clinical outcomes involving vitamin D. Mol Diagn Ther (2014) 0.91
What is the role of vitamin D in autism? Dermatoendocrinol (2013) 0.89
Vitamin D and cardiovascular disease prevention. Nat Rev Cardiol (2016) 0.88
The renin-angiotensin-aldosterone system and calcium-regulatory hormones. J Hum Hypertens (2015) 0.85
Correlates of 25-hydroxyvitamin D among Chinese breast cancer patients. PLoS One (2014) 0.82
Prevalence and prognostic implications of vitamin D deficiency in chronic kidney disease. Dis Markers (2015) 0.82
Correction of Low Vitamin D Improves Fatigue: Effect of Correction of Low Vitamin D in Fatigue Study (EViDiF Study). N Am J Med Sci (2014) 0.82
Fibroblast growth factor 23 and 25-hydroxyvitamin D levels are associated with estimated glomerular filtration rate decline. Kidney Int Suppl (2011) (2013) 0.82
Association of Maternal Vitamin D Status with Glucose Tolerance and Caesarean Section in a Multi-Ethnic Asian Cohort: The Growing Up in Singapore Towards Healthy Outcomes Study. PLoS One (2015) 0.81
A GC polymorphism associated with serum 25-hydroxyvitamin D level is a risk factor for hip fracture in Japanese patients with rheumatoid arthritis: 10-year follow-up of the Institute of Rheumatology, Rheumatoid Arthritis cohort study. Arthritis Res Ther (2014) 0.81
Evaluating hormonal mechanisms of vitamin D receptor agonist therapy in diabetic kidney disease: the VALIDATE-D study. BMC Endocr Disord (2013) 0.79
Vitamin D deficiency and mortality in patients receiving dialysis: the Comprehensive Dialysis Study. J Ren Nutr (2013) 0.79
Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants. PLoS One (2016) 0.79
Genetic associations with 25-hydroxyvitamin D deficiency in HIV-1-infected youth: fine-mapping for the GC/DBP gene that encodes the vitamin D-binding protein. Front Genet (2013) 0.78
Vitamin D receptor genetics on extracellular matrix biomarkers and hemodynamics in systolic heart failure. J Cardiovasc Pharmacol Ther (2014) 0.78
Vitamin D and cardio-metabolic disease. Metabolism (2013) 0.78
Impact of vitamin D deficiency on maternal and birth outcomes in the Saudi population: a cross-sectional study. BMC Pregnancy Childbirth (2016) 0.77
Vitamin D deficiency: consequence or cause of CKD? Clin J Am Soc Nephrol (2013) 0.76
Insights into genetic and epigenetic determinants with impact on vitamin d signaling and cancer association studies: the case of thyroid cancer. Front Oncol (2014) 0.76
Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study. PLoS One (2016) 0.75
Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people. Genes Nutr (2016) 0.75
Is Vitamin D an Independent Risk Factor of Nonalcoholic Fatty Liver Disease?: a Cross-Sectional Study of the Healthy Population. J Korean Med Sci (2017) 0.75
Genetic variants modifying the influence of vitamin D--reply. JAMA (2013) 0.75
Vitamin D in Chronic Kidney Disease and Dialysis Patients. Nutrients (2017) 0.75
The Association of Serum 25-Hydroxyvitamin D Status in Patients with Osteoarthritis in the Primary Care Office. N Am J Med Sci (2016) 0.75
Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska. J Nutr (2015) 0.75
Efficacy and safety of early supplementation with 800 IU of vitamin D in very preterm infants followed by underlying levels of vitamin D at birth. Ital J Pediatr (2017) 0.75
Impact of Childhood Malnutrition on Host Defense and Infection. Clin Microbiol Rev (2017) 0.75
Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial. JAMA Oncol (2016) 0.75
Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug Responses. Genomics Proteomics Bioinformatics (2017) 0.75
Vitamin D deficiency. N Engl J Med (2007) 59.34
The Cardiovascular Health Study: design and rationale. Ann Epidemiol (1991) 27.24
On estimating the relation between blood group and disease. Ann Hum Genet (1955) 26.39
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics (2008) 15.77
Vitamin D deficiency and risk of cardiovascular disease. Circulation (2008) 13.39
Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study. Ann Epidemiol (1995) 10.26
Subsystems contributing to the decline in ability to walk: bridging the gap between epidemiology and geriatric practice in the InCHIANTI study. J Am Geriatr Soc (2000) 10.19
25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med (2008) 9.50
1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest (2002) 9.50
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med (2008) 8.03
Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality. Arch Intern Med (2008) 7.21
Clinical practice. Vitamin D insufficiency. N Engl J Med (2011) 6.84
Measuring higher level physical function in well-functioning older adults: expanding familiar approaches in the Health ABC study. J Gerontol A Biol Sci Med Sci (2001) 4.01
Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems. Am J Physiol Endocrinol Metab (2004) 3.75
Quantitative trait Loci analysis using the false discovery rate. Genetics (2005) 3.69
Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol (2005) 3.44
25-hydroxyvitamin D levels inversely associate with risk for developing coronary artery calcification. J Am Soc Nephrol (2009) 2.87
Tracking of serum 25-hydroxyvitamin D levels during 14 years in a population-based study and during 12 months in an intervention study. Am J Epidemiol (2010) 2.66
The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease. Contemp Clin Trials (2011) 2.59
Vitamin D, parathyroid hormone, and cardiovascular events among older adults. J Am Coll Cardiol (2011) 2.56
Serum 25-hydroxyvitamin D concentrations and risk for hip fractures. Ann Intern Med (2008) 2.44
Vitamin D status and related parameters in a healthy population: the effects of age, sex, and season. J Clin Endocrinol Metab (1990) 2.05
Quantifying and correcting for the winner's curse in genetic association studies. Genet Epidemiol (2009) 2.02
Comparing methods for accounting for seasonal variability in a biomarker when only a single sample is available: insights from simulations based on serum 25-hydroxyvitamin d. Am J Epidemiol (2009) 1.89
The effects of seasonal variation of 25-hydroxyvitamin D and fat mass on a diagnosis of vitamin D sufficiency. Am J Clin Nutr (2007) 1.83
Review and meta-analysis on vitamin D receptor polymorphisms and cancer risk. Carcinogenesis (2009) 1.75
Measuring 25-hydroxyvitamin D in a clinical environment: challenges and needs. Am J Clin Nutr (2008) 1.60
Ligand modulates the conversion of DNA-bound vitamin D3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers. Mol Cell Biol (1994) 1.58
Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study. Am J Epidemiol (2011) 1.55
Serum 25-hydroxyvitamin D concentration and risk for major clinical disease events in a community-based population of older adults: a cohort study. Ann Intern Med (2012) 1.49
Plasma 25-hydroxyvitamin D levels and fracture risk in a community-based cohort of elderly men in Sweden. J Clin Endocrinol Metab (2010) 1.43
Meta-analysis of molecular association studies: vitamin D receptor gene polymorphisms and BMD as a case study. J Bone Miner Res (2003) 1.42
The association of bone mineral density with vitamin D receptor gene polymorphisms. Osteoporos Int (1999) 1.38
Serum 25-hydroxyvitamin D and hip fracture risk in older U.S. white adults. J Bone Miner Res (2008) 1.37
Vitamin D receptor gene polymorphisms and epithelial ovarian cancer risk. Cancer Epidemiol Biomarkers Prev (2007) 1.26
Mineral metabolism markers and the long-term risk of hip fracture: the cardiovascular health study. J Clin Endocrinol Metab (2011) 1.12
Functional analysis of novel SNPs and mutations in human and mouse genomes. BMC Bioinformatics (2008) 1.06
Vitamin D receptor genotypes influence the success of calcitriol therapy for recurrent vertebral fracture in osteoporosis. Pharmacogenet Genomics (2005) 1.05
Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk. PLoS One (2009) 1.03
BsmI, TaqI, ApaI and FokI polymorphisms in the vitamin D receptor (VDR) gene and risk of fracture in Caucasians: a meta-analysis. Bone (2010) 1.01
Vitamin D receptor polymorphisms in differentiated thyroid carcinoma. Thyroid (2009) 0.94
Association of genetic polymorphisms in vitamin D receptor gene and susceptibility to sporadic prostate cancer. Exp Biol Med (Maywood) (2008) 0.90
Discovering novel risk factors for venous thrombosis: a candidate-gene approach. Thromb Res (2009) 0.81
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation (2010) 19.30
Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med (2007) 18.27
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Gait speed and survival in older adults. JAMA (2011) 15.01
Vitamin D deficiency and risk of cardiovascular disease. Circulation (2008) 13.39
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA (2006) 12.47
Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci (2004) 12.46
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Opioid prescriptions for chronic pain and overdose: a cohort study. Ann Intern Med (2010) 11.99
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med (2008) 9.19
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci (2006) 8.00
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes. N Engl J Med (2011) 7.42
Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med (2013) 7.30
FGF23 induces left ventricular hypertrophy. J Clin Invest (2011) 7.22
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
A pooled analysis of vitamin D dose requirements for fracture prevention. N Engl J Med (2012) 6.85
Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc (2006) 6.81
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61
Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54
Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med (2011) 6.44
Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci (2005) 6.42
Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy. N Engl J Med (2003) 6.41
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci (2006) 6.08
Detection of life-threatening prostate cancer with prostate-specific antigen velocity during a window of curability. J Natl Cancer Inst (2006) 6.02
Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood (2004) 5.86
Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA (2011) 5.86
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Bone-density testing interval and transition to osteoporosis in older women. N Engl J Med (2012) 5.81
Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol (2005) 5.76
Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol (1985) (2003) 5.73
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47
Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. JAMA (2005) 5.46
Dynamic modularity in protein interaction networks predicts breast cancer outcome. Nat Biotechnol (2009) 5.41
Glycemic effects of postmenopausal hormone therapy: the Heart and Estrogen/progestin Replacement Study. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (2003) 5.38
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am J Epidemiol (2006) 5.28
Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med (2007) 5.26
High-throughput mapping of a dynamic signaling network in mammalian cells. Science (2005) 5.21
Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med (2010) 5.20
Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet (2009) 5.20
Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med (2008) 5.14
High-trauma fractures and low bone mineral density in older women and men. JAMA (2007) 5.00
Frailty: an emerging research and clinical paradigm--issues and controversies. J Gerontol A Biol Sci Med Sci (2007) 4.98
Inflammation as a risk factor for atrial fibrillation. Circulation (2003) 4.95
Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. Circulation (2009) 4.87