Published in Nucleic Acids Res on May 05, 2010
Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data. Bioinformatics (2011) 4.31
Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format. Bioinformatics (2011) 1.61
Genome Maps, a new generation genome browser. Nucleic Acids Res (2013) 1.33
Targeted exome sequencing identified novel USH2A mutations in Usher syndrome families. PLoS One (2013) 1.28
BamView: visualizing and interpretation of next-generation sequencing read alignments. Brief Bioinform (2012) 1.08
SICTIN: Rapid footprinting of massively parallel sequencing data. BioData Min (2010) 0.92
Discovery of Single Nucleotide Polymorphisms in Complex Genomes Using SGSautoSNP. Biology (Basel) (2012) 0.90
PileLineGUI: a desktop environment for handling genome position files in next-generation sequencing studies. Nucleic Acids Res (2011) 0.88
Unraveling genomic variation from next generation sequencing data. BioData Min (2013) 0.86
Comprehensive molecular diagnosis of Bardet-Biedl syndrome by high-throughput targeted exome sequencing. PLoS One (2014) 0.86
Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and future. Gigascience (2015) 0.85
LayerCake: a tool for the visual comparison of viral deep sequencing data. Bioinformatics (2015) 0.85
Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection. Microarrays (Basel) (2015) 0.83
Use of targeted exome sequencing in genetic diagnosis of Chinese familial hypercholesterolemia. PLoS One (2014) 0.83
Investigation of Pathogenic Genes in Chinese sporadic Hypertrophic Cardiomyopathy Patients by Whole Exome Sequencing. Sci Rep (2015) 0.82
Trends in IT Innovation to Build a Next Generation Bioinformatics Solution to Manage and Analyse Biological Big Data Produced by NGS Technologies. Biomed Res Int (2015) 0.80
STAR: an integrated solution to management and visualization of sequencing data. Bioinformatics (2013) 0.78
GenomeGems: evaluation of genetic variability from deep sequencing data. BMC Res Notes (2012) 0.75
Identification of a novel DMD duplication identified by a combination of MLPA and targeted exome sequencing. Mol Cytogenet (2017) 0.75
A novel deleterious mutation in the COMP gene that causes pseudoachondroplasia. Hum Genome Var (2016) 0.75
ARYANA: Aligning Reads by Yet Another Approach. BMC Bioinformatics (2014) 0.75
Use of high-throughput targeted exome sequencing in genetic diagnosis of Chinese family with congenital cataract. Int J Ophthalmol (2016) 0.75
The Sequence Alignment/Map format and SAMtools. Bioinformatics (2009) 232.39
Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res (2008) 157.44
Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08
Next-generation DNA sequencing. Nat Biotechnol (2008) 34.95
Tablet--next generation sequence assembly visualization. Bioinformatics (2009) 11.75
EagleView: a genome assembly viewer for next-generation sequencing technologies. Genome Res (2008) 7.50
Computational methods for discovering structural variation with next-generation sequencing. Nat Methods (2009) 7.20
MapView: visualization of short reads alignment on a desktop computer. Bioinformatics (2009) 6.77
Next-generation DNA sequencing techniques. N Biotechnol (2009) 6.02
BamView: viewing mapped read alignment data in the context of the reference sequence. Bioinformatics (2010) 3.24
LookSeq: a browser-based viewer for deep sequencing data. Genome Res (2009) 2.70
inGAP: an integrated next-generation genome analysis pipeline. Bioinformatics (2009) 2.06
Next-generation gap. Nat Methods (2009) 2.01
Bioinformatics approaches for genomics and post genomics applications of next-generation sequencing. Brief Bioinform (2009) 1.72
NGSView: an extensible open source editor for next-generation sequencing data. Bioinformatics (2009) 1.20
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Complete Khoisan and Bantu genomes from southern Africa. Nature (2010) 9.06
Sequencing the nuclear genome of the extinct woolly mammoth. Nature (2008) 4.31
Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice. Cell Metab (2013) 2.49
The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus). Genome Res (2009) 2.30
Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy. J Am Coll Cardiol (2006) 2.21
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen. Nucleic Acids Res (2005) 2.21
Evaluation and discovery of novel synthetic chalcone derivatives as anti-inflammatory agents. J Med Chem (2011) 2.18
inGAP: an integrated next-generation genome analysis pipeline. Bioinformatics (2009) 2.06
Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents. Bioorg Med Chem (2008) 2.03
Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil). Proc Natl Acad Sci U S A (2011) 1.99
Polar and brown bear genomes reveal ancient admixture and demographic footprints of past climate change. Proc Natl Acad Sci U S A (2012) 1.98
Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart. J Am Coll Cardiol (2008) 1.95
Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo. Diabetes (2011) 1.84
Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages. Bioorg Med Chem (2010) 1.73
mirTools: microRNA profiling and discovery based on high-throughput sequencing. Nucleic Acids Res (2010) 1.70
Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Nat Commun (2013) 1.65
HTQC: a fast quality control toolkit for Illumina sequencing data. BMC Bioinformatics (2013) 1.58
Attenuation of diabetes-induced renal dysfunction by multiple exposures to low-dose radiation is associated with the suppression of systemic and renal inflammation. Am J Physiol Endocrinol Metab (2009) 1.51
Serum levels of FGF-21 are increased in coronary heart disease patients and are independently associated with adverse lipid profile. PLoS One (2010) 1.50
Complete genome sequence of bacteriophage T5. Virology (2005) 1.48
Metagenomic profile of the bacterial communities associated with Ixodes ricinus ticks. PLoS One (2011) 1.43
Dysbiosis signature of fecal microbiota in colorectal cancer patients. Microb Ecol (2013) 1.37
inGAP-sv: a novel scheme to identify and visualize structural variation from paired end mapping data. Nucleic Acids Res (2011) 1.31
Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB. PLoS One (2012) 1.30
Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease. Sci Rep (2013) 1.30
Enhanced wound-healing quality with bone marrow mesenchymal stem cells autografting after skin injury. Wound Repair Regen (2006) 1.28
Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing. PLoS One (2010) 1.21
Synthesis and anti-bacterial properties of mono-carbonyl analogues of curcumin. Chem Pharm Bull (Tokyo) (2008) 1.21
Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages. Eur J Med Chem (2010) 1.20
Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy. Am J Physiol Renal Physiol (2009) 1.19
Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane. PLoS Negl Trop Dis (2010) 1.16
Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage. Bioorg Med Chem (2009) 1.16
Adipose tissue extract enhances skin wound healing. Wound Repair Regen (2007) 1.16
Composition-based classification of short metagenomic sequences elucidates the landscapes of taxonomic and functional enrichment of microorganisms. Nucleic Acids Res (2012) 1.16
Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin. Bioorg Med Chem Lett (2008) 1.16
Oxidative stress, diabetes, and diabetic complications. Hemoglobin (2009) 1.15
PGA4genomics for comparative genome assembly based on genetic algorithm optimization. Genomics (2009) 1.13
1-Phenyl-3-(2,4,6-trimethoxy-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2009) 1.13
Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. Gut (2012) 1.10
Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin. J Cell Mol Med (2009) 1.10
Sequencing and genetic variation of multidrug resistance plasmids in Klebsiella pneumoniae. PLoS One (2010) 1.10
Anticancer molecules targeting fibroblast growth factor receptors. Trends Pharmacol Sci (2012) 1.10
Characterization of the stress associated microRNAs in Glycine max by deep sequencing. BMC Plant Biol (2011) 1.08
Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues. Eur J Med Chem (2008) 1.08
Exome sequencing reveals CCDC111 mutation associated with high myopia. Hum Genet (2013) 1.07
Circulating FGF21 levels are progressively increased from the early to end stages of chronic kidney diseases and are associated with renal function in Chinese. PLoS One (2011) 1.05
HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages. Biochem Pharmacol (2009) 1.04
Mutations of ANK3 identified by exome sequencing are associated with autism susceptibility. Hum Mutat (2012) 1.04
bFGF inhibits ER stress induced by ischemic oxidative injury via activation of the PI3K/Akt and ERK1/2 pathways. Toxicol Lett (2012) 1.03
Small molecule inhibition of fibroblast growth factor receptors in cancer. Cytokine Growth Factor Rev (2013) 1.02
Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats. Br J Pharmacol (2012) 1.02
Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury. J Transl Med (2014) 1.01
Engineered growth factors and cutaneous wound healing: success and possible questions in the past 10 years. Wound Repair Regen (2005) 1.01
De novo transcriptome of safflower and the identification of putative genes for oleosin and the biosynthesis of flavonoids. PLoS One (2012) 1.01
Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse. Schizophr Res (2008) 1.01
Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice. J Mol Med (Berl) (2009) 1.01
Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development. Mol Microbiol (2013) 1.00
Molecular characterization and antimicrobial susceptibility of nasal Staphylococcus aureus isolates from a Chinese medical college campus. PLoS One (2011) 1.00
Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner. J Am Coll Cardiol (2012) 1.00
A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway. J Med Chem (2011) 0.99
Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. Toxicol Lett (2013) 0.99
Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage. Am J Physiol Endocrinol Metab (2011) 0.99
Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress-induced decrease in cell proliferation and BDNF expression in rat hippocampus. Hippocampus (2006) 0.98
Acceleration of diabetic wound healing with chitosan-crosslinked collagen sponge containing recombinant human acidic fibroblast growth factor in healing-impaired STZ diabetic rats. Life Sci (2007) 0.98
ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. Antimicrob Agents Chemother (2010) 0.97
Insights into the evolution of gene organization and multidrug resistance from Klebsiella pneumoniae plasmid pKF3-140. Gene (2013) 0.97
A close phylogenetic relationship between Sipuncula and Annelida evidenced from the complete mitochondrial genome sequence of Phascolosoma esculenta. BMC Genomics (2009) 0.96
Chemoprotective effects of Curcuma aromatica on esophageal carcinogenesis. Ann Surg Oncol (2008) 0.96
bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway. J Cell Mol Med (2014) 0.95
Attenuation of high-glucose-induced inflammatory response by a novel curcumin derivative B06 contributes to its protection from diabetic pathogenic changes in rat kidney and heart. J Nutr Biochem (2012) 0.94
Carotenoid biosynthesis in cyanobacteria: structural and evolutionary scenarios based on comparative genomics. Int J Biol Sci (2006) 0.94
The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation. Learn Mem (2009) 0.94
Genome-wide analysis of restriction-modification system in unicellular and filamentous cyanobacteria. Physiol Genomics (2005) 0.94
Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic mice. PLoS One (2013) 0.93
The effects of chronic administration of quetiapine on the methamphetamine-induced recognition memory impairment and dopaminergic terminal deficit in rats. Behav Brain Res (2006) 0.93
A novel CXCR4 antagonist derived from human SDF-1beta enhances angiogenesis in ischaemic mice. Cardiovasc Res (2009) 0.93
Cracking the molecular origin of intrinsic tyrosine kinase activity through analysis of pathogenic gain-of-function mutations. Cell Rep (2013) 0.93
Nodeomics: pathogen detection in vertebrate lymph nodes using meta-transcriptomics. PLoS One (2010) 0.92
Diabetes-induced hepatic pathogenic damage, inflammation, oxidative stress, and insulin resistance was exacerbated in zinc deficient mouse model. PLoS One (2012) 0.92
Role of contrast-enhanced ultrasonography in percutaneous radiofrequency ablation of liver metastases and efficacy evaluation. Chin J Cancer Res (2013) 0.91
ArchaeaTF: an integrated database of putative transcription factors in Archaea. Genomics (2007) 0.91
Evaluation of a curcumin analog as an anti-cancer agent inducing ER stress-mediated apoptosis in non-small cell lung cancer cells. BMC Cancer (2013) 0.90
Detection, annotation and visualization of alternative splicing from RNA-Seq data with SplicingViewer. Genomics (2011) 0.90
Cardiac protection by basic fibroblast growth factor from ischemia/reperfusion-induced injury in diabetic rats. Biol Pharm Bull (2010) 0.90
Preparation and characterisation of bFGF-encapsulated liposomes and evaluation of wound-healing activities in the rat. Burns (2011) 0.90