Published in Med Microbiol Immunol on May 08, 2010
Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91
Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures. EMBO J (2013) 1.61
The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biol Open (2012) 0.95
Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens. Nat Rev Microbiol (2013) 0.95
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic. J Biol Chem (2012) 0.90
Modulation of translation and induction of autophagy by bacterial exoproducts. Med Microbiol Immunol (2012) 0.90
BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins. Am J Physiol Cell Physiol (2015) 0.88
Serratia marcescens ShlA pore-forming toxin is responsible for early induction of autophagy in host cells and is transcriptionally regulated by RcsB. Infect Immun (2014) 0.85
Phobalysin, a Small β-Pore-Forming Toxin of Photobacterium damselae subsp. damselae. Infect Immun (2015) 0.83
Methicillin-resistant Staphylococcus aureus adaptation to human keratinocytes. MBio (2015) 0.82
Recent publications in medical microbiology and immunology: a retrospective. Med Microbiol Immunol (2011) 0.81
Statin-Conferred Enhanced Cellular Resistance against Bacterial Pore-Forming Toxins in Airway Epithelial Cells. Am J Respir Cell Mol Biol (2015) 0.79
The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases. Oncotarget (2016) 0.78
Listeriolysin O: from bazooka to Swiss army knife. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
Interactions between Autophagy and Bacterial Toxins: Targets for Therapy? Toxins (Basel) (2015) 0.77
Signaling beyond Punching Holes: Modulation of Cellular Responses by Vibrio cholerae Cytolysin. Toxins (Basel) (2015) 0.77
The role of autophagy in microbial infection and immunity. Immunotargets Ther (2015) 0.76
AMP-activated Protein Kinase As a Target For Pathogens: Friends Or Foes? Curr Drug Targets (2016) 0.75
eIF2α Confers Cellular Tolerance to S. aureus α-Toxin. Front Immunol (2015) 0.75
A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death. Front Cell Infect Microbiol (2017) 0.75
The ever-emerging complexity of α-toxin's interaction with host cells. Proc Natl Acad Sci U S A (2015) 0.75
Methods in mammalian autophagy research. Cell (2010) 20.08
Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell (2000) 17.44
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol (1988) 16.82
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell (2003) 15.12
Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet (2009) 14.06
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J Cell Biol (2001) 7.82
Coping with stress: eIF2 kinases and translational control. Biochem Soc Trans (2006) 7.69
Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci U S A (2001) 5.59
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell (2006) 4.63
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity (2005) 4.53
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell (2007) 3.46
Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun (2004) 3.39
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity (2000) 3.07
Amino acid regulation of TOR complex 1. Am J Physiol Endocrinol Metab (2008) 3.03
Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Proc Natl Acad Sci U S A (2004) 2.93
The TOR pathway comes of age. Biochim Biophys Acta (2009) 2.83
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2. Nature (2005) 2.67
Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis. J Cell Biol (2008) 2.66
Activation of the integrated stress response during T helper cell differentiation. Nat Immunol (2006) 2.62
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation. J Cell Biol (2010) 2.58
Unconventional secretion of Acb1 is mediated by autophagosomes. J Cell Biol (2010) 2.58
Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe (2009) 2.52
Novel path to apoptosis: small transmembrane pores created by staphylococcal alpha-toxin in T lymphocytes evoke internucleosomal DNA degradation. Infect Immun (1994) 2.47
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae. Proc Natl Acad Sci U S A (2007) 2.27
Bacterial pore-forming toxins: the (w)hole story? Cell Mol Life Sci (2008) 2.16
Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog (2008) 2.16
Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins. Arch Microbiol (1996) 2.11
Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells. Traffic (2007) 2.10
Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions. Infect Immun (1993) 2.09
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin. EMBO J (2000) 1.98
Staphylococcus aureus: new evidence for intracellular persistence. Trends Microbiol (2009) 1.92
Nutrient-dependent regulation of autophagy through the target of rapamycin pathway. Biochem Soc Trans (2009) 1.91
Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation. Proc Natl Acad Sci U S A (1998) 1.91
Amino acid transporters: roles in amino acid sensing and signalling in animal cells. Biochem J (2003) 1.84
Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses. EMBO J (2006) 1.79
Staphylococcus aureus subvert autophagy for induction of caspase-independent host cell death. J Biol Chem (2006) 1.73
Key residues for membrane binding, oligomerization, and pore forming activity of staphylococcal alpha-hemolysin identified by cysteine scanning mutagenesis and targeted chemical modification. J Biol Chem (1995) 1.73
Subcytocidal attack by staphylococcal alpha-toxin activates NF-kappaB and induces interleukin-8 production. Infect Immun (2001) 1.71
Mechanism of complement cytolysis and the concept of channel-forming proteins. Philos Trans R Soc Lond B Biol Sci (1984) 1.57
Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis. FEBS Lett (2008) 1.44
N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways. J Biol Chem (2006) 1.42
Pore-forming toxins and cellular non-immune defenses (CNIDs). Curr Opin Microbiol (2007) 1.40
Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans. PLoS Pathog (2009) 1.35
Differential role of p38 mitogen activated protein kinase for cellular recovery from attack by pore-forming S. aureus alpha-toxin or streptolysin O. Biochem Biophys Res Commun (2006) 1.34
Resealing of large transmembrane pores produced by streptolysin O in nucleated cells is accompanied by NF-kappaB activation and downstream events. FASEB J (2001) 1.28
Staphylococcus aureus host cell invasion and post-invasion events. Int J Med Microbiol (2009) 1.28
Recovery of human fibroblasts from attack by the pore-forming alpha-toxin of Staphylococcus aureus. Microb Pathog (1994) 1.27
Alpha-hemolysin is required for the activation of the autophagic pathway in Staphylococcus aureus-infected cells. Autophagy (2010) 1.25
Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction. J Biol Chem (1995) 1.24
Pore-forming Staphylococcus aureus alpha-toxin triggers epidermal growth factor receptor-dependent proliferation. Cell Microbiol (2006) 1.23
The expression of alpha-haemolysin is required for Staphylococcus aureus phagosomal escape after internalization in CFT-1 cells. Cell Microbiol (2008) 1.22
The protein kinase Gcn2p mediates sodium toxicity in yeast. J Biol Chem (2001) 1.21
Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions. J Biol Chem (2004) 1.20
Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium. Biochem Biophys Res Commun (2009) 1.15
Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection. PLoS One (2010) 1.14
Histidine residues near the N terminus of staphylococcal alpha-toxin as reporters of regions that are critical for oligomerization and pore formation. Infect Immun (1994) 1.12
Expression of active streptolysin O in Escherichia coli as a maltose-binding-protein--streptolysin-O fusion protein. The N-terminal 70 amino acids are not required for hemolytic activity. Eur J Biochem (1996) 1.11
WWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans. PLoS One (2010) 1.11
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. J Virol (2005) 0.94
Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells. Cell Calcium (2008) 0.92
GCN2 whets the appetite for amino acids. Mol Cell (2005) 0.89
The autophagic pathway: a cell survival strategy against the bacterial pore-forming toxin Vibrio cholerae cytolysin. Autophagy (2007) 0.87
Membrane damage by channel-forming proteins: staphylococcal alpha-toxin, streptolysin-O and the C5b-9 complement complex. Biochem Soc Symp (1985) 0.87
Streptolysin O: inhibition of the conformational change during membrane binding of the monomer prevents oligomerization and pore formation. Biochemistry (1999) 0.87
A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin. J Biol Chem (2004) 0.85
Signal transduction: Linking nutrients to growth. Nature (2008) 0.84
Fatty acids liberated from low-density lipoprotein trigger endothelial apoptosis via mitogen-activated protein kinases. Cell Death Differ (2005) 0.79
A bacterial pore-forming toxin forms aggregates in cells that resemble those associated with neurodegenerative diseases. Cell Microbiol (2007) 0.78
Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. J Infect Dis (2006) 2.82
Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer? Arterioscler Thromb Vasc Biol (2005) 1.66
Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs). PLoS One (2008) 1.63
Global functional analyses of cellular responses to pore-forming toxins. PLoS Pathog (2011) 1.52
Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis. FEBS Lett (2008) 1.44
Differential role of p38 mitogen activated protein kinase for cellular recovery from attack by pore-forming S. aureus alpha-toxin or streptolysin O. Biochem Biophys Res Commun (2006) 1.34
Resealing of large transmembrane pores produced by streptolysin O in nucleated cells is accompanied by NF-kappaB activation and downstream events. FASEB J (2001) 1.28
Highly focused T cell responses in latent human pulmonary Mycobacterium tuberculosis infection. J Immunol (2005) 1.28
Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequence. Circulation (2004) 1.26
Pore-forming Staphylococcus aureus alpha-toxin triggers epidermal growth factor receptor-dependent proliferation. Cell Microbiol (2006) 1.23
Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium. Biochem Biophys Res Commun (2009) 1.15
Human papillomavirus type 16 E7 peptide-directed CD8+ T cells from patients with cervical cancer are cross-reactive with the coronavirus NS2 protein. J Virol (2003) 1.09
Human papillomavirus types 16, 18, and 31 share similar endocytic requirements for entry. J Virol (2013) 1.01
Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis. EMBO J (2012) 1.01
Peptide-specific CD8+ T-cell evolution in vivo: response to peptide vaccination with Melan-A/MART-1. Int J Cancer (2002) 1.00
Longitudinal analysis of Mycobacterium tuberculosis 19-kDa antigen-specific T cells in patients with pulmonary tuberculosis: association with disease activity and cross-reactivity to a peptide from HIVenv gp120. Eur J Immunol (2003) 0.95
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. J Virol (2005) 0.94
Beyond cholesterol: the enigma of atherosclerosis revisited. Thromb Haemost (2004) 0.94
Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis. Arterioscler Thromb Vasc Biol (2004) 0.93
Characterization of the human endogenous retrovirus K Gag protein: identification of protease cleavage sites. Retrovirology (2011) 0.93
Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesicles. PLoS One (2009) 0.91
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic. J Biol Chem (2012) 0.90
Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicity. Thromb Haemost (2008) 0.90
Modulation of translation and induction of autophagy by bacterial exoproducts. Med Microbiol Immunol (2012) 0.90
Thrombin-induced interleukin 1beta synthesis in platelet suspensions: impact of contaminating leukocytes. Platelets (2007) 0.90
2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice. J Neurochem (2014) 0.85
Naturally processed and HLA-B8-presented HPV16 E7 epitope recognized by T cells from patients with cervical cancer. Int J Cancer (2005) 0.85
Interferons increase cell resistance to Staphylococcal alpha-toxin. Infect Immun (2007) 0.84
Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity. J Biol Chem (2011) 0.84
Genetic engineering of onco/lentivirus hybrids results in formation of infectious but not of replication-competent viruses. J Gen Virol (2004) 0.83
The receptor attachment function of measles virus hemagglutinin can be replaced with an autonomous protein that binds Her2/neu while maintaining its fusion-helper function. J Virol (2013) 0.82
Molecular basis of early epithelial response to streptococcal exotoxin: role of STIM1 and Orai1 proteins. Cell Microbiol (2011) 0.81
Differential MHC class II component expression in HPV-positive cervical cancer cells: implication for immune surveillance. Int J Cancer (2005) 0.81
Characterization of the early steps of human parvovirus B19 infection. J Virol (2012) 0.81
Enzymatically modified LDL induces cathepsin H in human monocytes: potential relevance in early atherogenesis. Arterioscler Thromb Vasc Biol (2003) 0.81
Improved detection of melanoma antigen-specific T cells expressing low or high levels of CD8 by HLA-A2 tetramers presenting a Melan-A/Mart-1 peptide analogue. Int J Cancer (2002) 0.79
Enzymatically modified nonoxidized low-density lipoprotein induces interleukin-8 in human endothelial cells: role of free fatty acids. Circulation (2002) 0.79
Isolation and characterization of an infectious replication-competent molecular clone of ecotropic porcine endogenous retrovirus class C. J Virol (2006) 0.78
Correction: The νSaα Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells. PLoS Pathog (2015) 0.75
Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein. Atherosclerosis (2009) 0.75
Enzymatically hydrolyzed low-density lipoprotein modulates inflammatory responses in endothelial cells. Thromb Haemost (2008) 0.75
Wavefront correction in the extreme ultraviolet wavelength range using piezoelectric thin films. Opt Express (2014) 0.75